BDBM11052 CHEMBL418037::N-(4-sulfamoylphenyl)-2-({2-[(4-sulfamoylphenyl)carbamoyl]phenyl}disulfanyl)benzamide::disulfide-containing sulfonamide 5a

SMILES NS(=O)(=O)c1ccc(NC(=O)c2ccccc2SSc2ccccc2C(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1

InChI Key InChIKey=FVGJPHFQQMQGFQ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 11052   

TargetCarbonic anhydrase 9(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11052(CHEMBL418037 | N-(4-sulfamoylphenyl)-2-({2-[(4-sul...)
Affinity DataKi:  653nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped flow techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11052(CHEMBL418037 | N-(4-sulfamoylphenyl)-2-({2-[(4-sul...)
Affinity DataKi:  653nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11052(CHEMBL418037 | N-(4-sulfamoylphenyl)-2-({2-[(4-sul...)
Affinity DataKi:  4.35E+3nM ΔG°:  -7.24kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11052(CHEMBL418037 | N-(4-sulfamoylphenyl)-2-({2-[(4-sul...)
Affinity DataKi:  4.35E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped flow techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11052(CHEMBL418037 | N-(4-sulfamoylphenyl)-2-({2-[(4-sul...)
Affinity DataKi:  4.98E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped flow techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11052(CHEMBL418037 | N-(4-sulfamoylphenyl)-2-({2-[(4-sul...)
Affinity DataKi:  4.98E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed