BDBM12130 3-(Indol-2-yl)indazole 20::6-phenyl-3-[5-(piperidin-1-ylmethyl)-1H-indol-2-yl]-1H-indazole

SMILES C(N1CCCCC1)c1ccc2[nH]c(cc2c1)-c1n[nH]c2cc(ccc12)-c1ccccc1

InChI Key InChIKey=PRNXBLOZTIGXJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12130   

TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

LigandPNGBDBM12130(6-phenyl-3-[5-(piperidin-1-ylmethyl)-1H-indol-2-yl...)
Affinity DataIC50: 45nMpH: 7.5 T: 2°CAssay Description:Kinase activity was measured in a homogeneous assay in a 96-well format. Detection was performed by HTRF using an EuK-labelled anti-phospho(S21)-GSK3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Merck Research Laboratories

LigandPNGBDBM12130(6-phenyl-3-[5-(piperidin-1-ylmethyl)-1H-indol-2-yl...)
Affinity DataIC50: 7.00E+3nMAssay Description:Kinase activity was measured in a homogeneous assay in a 96-well format. Detection was performed by HTRF using an EuK-labelled anti-phospho(S21)-GSK3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed