BDBM13423 CHEMBL167368::STX 118::[3-(2-cyclohexylethyl)-4-methyl-2-oxo-2H-chromen-7-yl] sulfamate

SMILES Cc1c(CCC2CCCCC2)c(=O)oc2cc(OS(N)(=O)=O)ccc12

InChI Key InChIKey=FCGPWKCJPCLCKH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13423   

TargetCarbonic anhydrase 2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM13423([3-(2-cyclohexylethyl)-4-methyl-2-oxo-2H-chromen-7...)
Affinity DataIC50: 15nMAssay Description:Compound was tested for inhibition of human carbonic anhydrase (hCA II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
St. Mary'S Hospital

LigandPNGBDBM13423([3-(2-cyclohexylethyl)-4-methyl-2-oxo-2H-chromen-7...)
Affinity DataIC50: 46nMAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM13423([3-(2-cyclohexylethyl)-4-methyl-2-oxo-2H-chromen-7...)
Affinity DataIC50: 59nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed