BDBM13453 N-[(3S)-2-[3-(4-methoxyphenyl)propanoyl]-3-(methylcarbamoyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]sulfamic acid::Tetrahydroisoquinoline (TIQ) deriv. 10a

SMILES CNC(=O)[C@@H]1Cc2ccc(NS(O)(=O)=O)cc2CN1C(=O)CCc1ccc(OC)cc1

InChI Key InChIKey=HIFLGNOXUZTUCD-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13453   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13453(N-[(3S)-2-[3-(4-methoxyphenyl)propanoyl]-3-(methyl...)
Affinity DataIC50: 2.42E+5nMAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed