BDBM18929 2-{3,5-dichloro-4-[4-hydroxy-3-(2-hydroxyphenyl)phenoxy]phenyl}acetic acid::4-hydroxy thyromimetic, 9k

SMILES OC(=O)Cc1cc(Cl)c(Oc2ccc(O)c(c2)-c2ccccc2O)c(Cl)c1

InChI Key InChIKey=SUVVBULKISMRAD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18929   

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18929(2-{3,5-dichloro-4-[4-hydroxy-3-(2-hydroxyphenyl)ph...)
Affinity DataIC50: 50nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18929(2-{3,5-dichloro-4-[4-hydroxy-3-(2-hydroxyphenyl)ph...)
Affinity DataIC50: 50.1nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18929(2-{3,5-dichloro-4-[4-hydroxy-3-(2-hydroxyphenyl)ph...)
Affinity DataIC50: 50.1nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM18929(2-{3,5-dichloro-4-[4-hydroxy-3-(2-hydroxyphenyl)ph...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM18929(2-{3,5-dichloro-4-[4-hydroxy-3-(2-hydroxyphenyl)ph...)
Affinity DataIC50: 1.05E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2007
Entry Details Article
PubMed