BDBM18934 2-{3,5-dichloro-4-[4-hydroxy-3-(pyridin-4-yl)phenoxy]phenyl}acetic acid::4-hydroxy thyromimetic, 9p

SMILES OC(=O)Cc1cc(Cl)c(Oc2ccc(O)c(c2)-c2ccncc2)c(Cl)c1

InChI Key InChIKey=PUUWWSIUTRYHMF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18934   

TargetThyroid hormone receptor beta(Human)
University of Insubria

Curated by ChEMBL
LigandPNGBDBM18934(2-{3,5-dichloro-4-[4-hydroxy-3-(pyridin-4-yl)pheno...)
Affinity DataIC50: 123nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of Insubria

Curated by ChEMBL
LigandPNGBDBM18934(2-{3,5-dichloro-4-[4-hydroxy-3-(pyridin-4-yl)pheno...)
Affinity DataIC50: 123nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of Insubria

Curated by ChEMBL
LigandPNGBDBM18934(2-{3,5-dichloro-4-[4-hydroxy-3-(pyridin-4-yl)pheno...)
Affinity DataIC50: 124nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM18934(2-{3,5-dichloro-4-[4-hydroxy-3-(pyridin-4-yl)pheno...)
Affinity DataIC50: 145nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM18934(2-{3,5-dichloro-4-[4-hydroxy-3-(pyridin-4-yl)pheno...)
Affinity DataIC50: 145nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2007
Entry Details Article
PubMed