BDBM50169639 2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-5-ethyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one::CHEMBL414842

SMILES CCCc1nc(CC)c2n1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1

InChI Key InChIKey=ZLOXKBYVNBOBAO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169639   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50169639(2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 8nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50169639(2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed