BDBM50212492 4'-{7-[(2-dimethylamino-ethylamino)-methyl]-1,4-dihydro-indeno[1,2-c]pyrazol-3-yl}-biphenyl-4-ol::CHEMBL234867

SMILES CN(C)CCNCc1ccc2Cc3c(n[nH]c3-c2c1)-c1ccc(cc1)-c1ccc(O)cc1

InChI Key InChIKey=CRJUDBADHREOSS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212492   

TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212492(4'-{7-[(2-dimethylamino-ethylamino)-methyl]-1,4-di...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed