BDBM50220963 1-[3-((3R,3aR)-2-acetyl-8-fluoro-3-phenyl-3a,4-dihydro-3H-5-oxa-1,9b-diaza-cyclopenta[a]naphthalen-3-yl)-propyl]-[1,4]diazepan-5-one::CHEMBL438876

SMILES CC(=O)C1=NN2[C@@H](COc3ccc(F)cc23)[C@@]1(CCCN1CCNC(=O)CC1)c1ccccc1

InChI Key InChIKey=SWZQJGBKFZAFAX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220963   

TargetKinesin-like protein KIF11(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220963(1-[3-((3R,3aR)-2-acetyl-8-fluoro-3-phenyl-3a,4-dih...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220963(1-[3-((3R,3aR)-2-acetyl-8-fluoro-3-phenyl-3a,4-dih...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed