BDBM50245248 (S)-N4-hydroxy-2-isobutyl-N1-((S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl)succinamide::CHEMBL452083

SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CC(C)C)CC(=O)NO

InChI Key InChIKey=MOPRTFSMCQNUCT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50245248   

TargetNeutrophil collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50245248((S)-N4-hydroxy-2-isobutyl-N1-((S)-1-(methylamino)-...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50245248((S)-N4-hydroxy-2-isobutyl-N1-((S)-1-(methylamino)-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50245248((S)-N4-hydroxy-2-isobutyl-N1-((S)-1-(methylamino)-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50245248((S)-N4-hydroxy-2-isobutyl-N1-((S)-1-(methylamino)-...)
Affinity DataIC50: 640nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50245248((S)-N4-hydroxy-2-isobutyl-N1-((S)-1-(methylamino)-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50245248((S)-N4-hydroxy-2-isobutyl-N1-((S)-1-(methylamino)-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed