BDBM50308986 2,4-Dichloro-5-sulphamoylbenzoate (2)::CHEMBL590825::pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoylbenzoate

SMILES NS(=O)(=O)c1cc(C([O-])=O)c(Cl)cc1Cl

InChI Key InChIKey=ZSHHRBYVHTVRFK-UHFFFAOYSA-M

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50308986   

TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 60nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 75nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; B lb l et al., J. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 100nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 130nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 137nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; B lb l et al., J. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 140nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 150nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 150nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 157nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; B lb l et al., J. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human erythrocytes CA2 by Lineweaver-Burke analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 250nMAssay Description:Inhibition of CA1 from human erythrocytes by Lineweaver-Burke analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 260nMAssay Description:Inhibition of hydratase-activity of CA1 from human erythrocytes by CO2-hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 290nMAssay Description:Inhibition of esterase-activity of human erythrocytes CA2 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 300nMAssay Description:Inhibition of hydratase-activity of human erythrocytes CA2 by CO2-hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 320nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 320nMAssay Description:Inhibition of esterase-activity of CA1 from human erythrocytes by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 800nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 990nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; B lb l et al., J. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed