BDBM50329826 2-Chloro-5-[(2-isopropyl-1H-benzimidazol-1-yl)acetyl]benzenesulfonamide::CHEMBL1271477::N-alkylated benzimidazole derivative, 4h

SMILES CC(C)c1nc2ccccc2n1CC(=O)c1ccc(Cl)c(c1)S(N)(=O)=O

InChI Key InChIKey=WUUDGCDESQAUGH-UHFFFAOYSA-N

Data  9 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50329826   

TargetCarbonic anhydrase 13(Human)
Vilnius University

LigandPNGBDBM50329826(2-Chloro-5-[(2-isopropyl-1H-benzimidazol-1-yl)acet...)
Affinity DataKd:  370nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Human)
Vilnius University

LigandPNGBDBM50329826(2-Chloro-5-[(2-isopropyl-1H-benzimidazol-1-yl)acet...)
Affinity DataKd:  400nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 13 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Vilnius University

LigandPNGBDBM50329826(2-Chloro-5-[(2-isopropyl-1H-benzimidazol-1-yl)acet...)
Affinity DataKd:  588nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM50329826(2-Chloro-5-[(2-isopropyl-1H-benzimidazol-1-yl)acet...)
Affinity DataKd:  667nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM50329826(2-Chloro-5-[(2-isopropyl-1H-benzimidazol-1-yl)acet...)
Affinity DataKd:  700nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50329826(2-Chloro-5-[(2-isopropyl-1H-benzimidazol-1-yl)acet...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50329826(2-Chloro-5-[(2-isopropyl-1H-benzimidazol-1-yl)acet...)
Affinity DataKd:  2.00E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50329826(2-Chloro-5-[(2-isopropyl-1H-benzimidazol-1-yl)acet...)
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50329826(2-Chloro-5-[(2-isopropyl-1H-benzimidazol-1-yl)acet...)
Affinity DataKd:  4.54E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed