BDBM50332176 (S)-1-(3-(3-aminoazepane-1-carbonyl)-5-(4-chlorophenyl)thiophen-2-yl)urea::CHEMBL1288161

SMILES N[C@H]1CCCCN(C1)C(=O)c1cc(sc1NC(N)=O)-c1ccc(Cl)cc1

InChI Key InChIKey=MNBNRGSPKFNOBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332176   

TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332176((S)-1-(3-(3-aminoazepane-1-carbonyl)-5-(4-chloroph...)
Affinity DataIC50: 746nMAssay Description:Inhibition of His-tagged CHK1 after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed