BDBM50339598 2-(3-chloro-4-hydroxyphenyl)-N-phenethylacetamide::CHEMBL601464

SMILES Oc1ccc(CC(=O)NCCc2ccccc2)cc1Cl

InChI Key InChIKey=RKDFOLFWZFYJCY-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50339598   

TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339598(2-(3-chloro-4-hydroxyphenyl)-N-phenethylacetamide ...)
Affinity DataKi:  800nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase(Cryptococcus neoformans var. grubii (Filobasidiell...)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339598(2-(3-chloro-4-hydroxyphenyl)-N-phenethylacetamide ...)
Affinity DataKi:  810nMAssay Description:Inhibition of Cryptococcus neoformans recombinant Can2 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase(Yeast)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339598(2-(3-chloro-4-hydroxyphenyl)-N-phenethylacetamide ...)
Affinity DataKi:  930nMAssay Description:Inhibition of Candida albicans recombinant Nce103 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339598(2-(3-chloro-4-hydroxyphenyl)-N-phenethylacetamide ...)
Affinity DataKi:  970nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant Rv3273 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50339598(2-(3-chloro-4-hydroxyphenyl)-N-phenethylacetamide ...)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of human 17beta-HSD2 expressed in HEK293 cell lysates incubated for 10 mins using [2,4,6,7-3H]-estradiol and NAD+ by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339598(2-(3-chloro-4-hydroxyphenyl)-N-phenethylacetamide ...)
Affinity DataKi:  9.60E+3nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339598(2-(3-chloro-4-hydroxyphenyl)-N-phenethylacetamide ...)
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed