BDBM5552 4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-N-methylbenzamide::4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}-N-methylbenzamide::O6-Cyclohexylmethylguanine deriv. 36

SMILES CNC(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1

InChI Key InChIKey=YAVWDSSODXPSHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5552   

TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Human)
University of Newcastle

LigandPNGBDBM5552(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}-N-m...)
Affinity DataIC50: 200nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
University of Newcastle

LigandPNGBDBM5552(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}-N-m...)
Affinity DataIC50: 400nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed