BDBM68253 Microlactone, 25

SMILES COc1cc(OC)c2c(CC(=O)CCCC\C=C\CC(C)OC2=O)c1Cl

InChI Key InChIKey=AOEJIUXBZKJWKW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 68253   

TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68253(Microlactone, 25)
Affinity DataIC50: 2.40E+4nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68253(Microlactone, 25)
Affinity DataIC50: 3.82E+4nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68253(Microlactone, 25)
Affinity DataIC50: 1.00E+5nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMed