BDBM68254 Microlactone, 26

SMILES COc1cc(OC)c2c(CC(=O)CCCC[C@H]3O[C@@H]3CC(C)OC2=O)c1Cl

InChI Key InChIKey=UJRRGZSMTQZVHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 68254   

TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68254(Microlactone, 26)
Affinity DataIC50: 5.84E+4nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68254(Microlactone, 26)
Affinity DataIC50: 1.00E+5nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMed