BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 76292 CCn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccccc1 InChI=1S/C14H13N5O2/c1-3-19-12-10(13(20)18(2)14(21)16-12)15-11(17-19)9-7-5-4-6-8-9/h4-8H,3H2,1-2H3 HJXOIRIPJDWFBS-UHFFFAOYSA-N 31040 1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione::1-ethyl-6-methyl-3-phenyl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione::1-ethyl-6-methyl-3-phenyl-pyrimido[5,4-e][1,2,4]triazine-5,7-quinone::1-ethyl-6-methyl-3-phenylpyrimido[5,4-e][1,2,4]triazine-5,7-dione::MLS000027832::SMR000008919::US9073941, 602::cid_647501 Heat shock protein HSP 90-alpha Homo sapiens 2728.8 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31040&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 647501 252615292 ZINC00487873 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76293 CCn1nc(nc2c1nc(=O)n(C)c2=O)-c1cccs1 InChI=1S/C12H11N5O2S/c1-3-17-10-8(11(18)16(2)12(19)14-10)13-9(15-17)7-5-4-6-20-7/h4-6H,3H2,1-2H3 DMDNERFCUCYCGM-UHFFFAOYSA-N 31044 1-Ethyl-6-methyl-3-thiophen-2-yl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione::1-ethyl-6-methyl-3-(2-thienyl)pyrimido[5,4-e][1,2,4]triazine-5,7-quinone::1-ethyl-6-methyl-3-thiophen-2-yl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione::1-ethyl-6-methyl-3-thiophen-2-ylpyrimido[5,4-e][1,2,4]triazine-5,7-dione::MLS000033110::SMR000008918::US9073941, 610::cid_653297 Heat shock protein HSP 90-alpha Homo sapiens <1875 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31044&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 653297 252615296 ZINC00487462 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76294 COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O InChI=1S/C27H29NO10/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3/t10-,14-,16-,17-,22+,27-/m0/s1 STQGQHZAVUOBTE-VGBVRHCVSA-N 32017 (7S,9S)-7-[(2R,4S,5S,6S)-4-azanyl-6-methyl-5-oxidanyl-oxan-2-yl]oxy-9-ethanoyl-4-methoxy-6,9,11-tris(oxidanyl)-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride::(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-quinone;hydrochloride::(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride::(7S,9S)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride::DAUNORUBICIN HYDROCHLORIDE::Daunorubicin::MLS000069508::SMR000058559::cid_62770 Heat shock protein HSP 90-alpha Homo sapiens 29270.1 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32017&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search DM1 3F8F,4KR8,308D,152D,1D33,7QZ6,7QZ7,7QZ8,427D,1VTI,1VTH,1D10,1D11,3TVB,1JO2,2D34,110D,1O0K,1DA0 30323 252615476 DB00694 C01907 ZINC03917708 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76295 C[C@H]1CCCC(=O)CCCCCc2cc(O)cc(O)c2C(=O)O1 InChI=1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,20-21H,2-9H2,1H3/t12-/m0/s1 APJDQUGPCJRQRJ-LBPRGKRZSA-N 32019 (11S)-11-methyl-15,17-bis(oxidanyl)-12-oxabicyclo[12.4.0]octadeca-1(18),14,16-triene-7,13-dione::(11S)-15,17-dihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(18),14,16-triene-7,13-dione::(11S)-15,17-dihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(18),14,16-triene-7,13-quinone::2,4-DIHYDROXY-6-[10-HYDROXY-6-OXO-UNDECYL]BENZOIC ACID MICRO-LACTONE::CHEMBL491499::MLS000069626::SMR000058193::cid_108003 Heat shock protein HSP 90-alpha Homo sapiens >30000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32019&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 108003 252615478 CHEMBL491499 C14754 ZINC03957079 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76296 CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3 HCZKYJDFEPMADG-UHFFFAOYSA-N 32020 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol::4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol::4-[4-[3,4-bis(oxidanyl)phenyl]-2,3-dimethyl-butyl]benzene-1,2-diol::BDBM166684::CHEMBL52::LOX inhibitor, N/A::MLS000069451::NORDIHYDROGUAIARETIC ACID::Nordihydroguaiaretic acid (NDGA)::SMR000059049::US10857082, Compound 2.18::cid_4534 Heat shock protein HSP 90-alpha Homo sapiens >30000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32020&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 30Z 6N2W,3ZQT,4PWJ 4534 252615479 7625 CHEMBL52 4265 ZINC00056474 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76297 COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 32022 (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-9-glycoloyl-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-quinone;hydrochloride::(7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride::(7S,9S)-7-[(2R,4S,5S,6S)-4-azanyl-6-methyl-5-oxidanyl-oxan-2-yl]oxy-4-methoxy-6,9,11-tris(oxidanyl)-9-(2-oxidanylethanoyl)-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride::(7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride::DOXORUBICIN HYDROCHLORIDE::MLS000028393::SMR000058570::cid_443939 Heat shock protein HSP 90-alpha Homo sapiens >30000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32022&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search DM2 5OM7,5MRA,6FTP,6KN4,1P20,1D12,1I1E,4DX7,2DR6,4ZVM,7CSK,151D,1DA9 31703 252615481 28748 DB00997 C01661 ZINC03918087 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76298 O=C1c2ccccc2-c2onc3ccc(NCCCn4ccnc4)c1c23 InChI=1S/C20H16N4O2/c25-19-13-4-1-2-5-14(13)20-18-16(23-26-20)7-6-15(17(18)19)22-8-3-10-24-11-9-21-12-24/h1-2,4-7,9,11-12,22H,3,8,10H2 SIJFRVCYVJSYJY-UHFFFAOYSA-N 32050 MLS000080844::SMR000044769::cid_663844 Heat shock protein HSP 90-alpha Homo sapiens >30000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32050&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 663844 242052851 ZINC02417895 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76299 Nc1nc(cc2c(C#N)c(nc(N)c12)N1CCCC1)N1CCCC1 InChI=1S/C17H21N7/c18-10-12-11-9-13(23-5-1-2-6-23)21-15(19)14(11)16(20)22-17(12)24-7-3-4-8-24/h9H,1-8H2,(H2,19,21)(H2,20,22) SSWVPYMSHHEYAB-UHFFFAOYSA-N 32061 1,8-bis(azanyl)-3,6-dipyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile::1,8-diamino-3,6-bis(1-pyrrolidinyl)-2,7-naphthyridine-4-carbonitrile::1,8-diamino-3,6-dipyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile::1,8-diamino-3,6-dipyrrolidino-2,7-naphthyridine-4-carbonitrile::MLS000054131::SMR000061605::cid_2997948 Heat shock protein HSP 90-alpha Homo sapiens >30000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32061&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 2997948 252615513 ZINC25386462 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76300 Cc1c(oc2ccc(F)cc2c1=O)-c1nn(C)c(=O)c2ccccc12 InChI=1S/C19H13FN2O3/c1-10-17(23)14-9-11(20)7-8-15(14)25-18(10)16-12-5-3-4-6-13(12)19(24)22(2)21-16/h3-9H,1-2H3 OJGFIJSOTGXACX-UHFFFAOYSA-N 32064 4-(6-fluoranyl-3-methyl-4-oxidanylidene-chromen-2-yl)-2-methyl-phthalazin-1-one::4-(6-fluoro-3-methyl-4-oxo-1-benzopyran-2-yl)-2-methyl-1-phthalazinone::4-(6-fluoro-3-methyl-4-oxochromen-2-yl)-2-methylphthalazin-1-one::4-(6-fluoro-4-keto-3-methyl-chromen-2-yl)-2-methyl-phthalazin-1-one::MLS000053550::SMR000066427::cid_2098006 Heat shock protein HSP 90-alpha Homo sapiens >30000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32064&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 2098006 252615516 ZINC02635384 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76301 CCn1c(CSc2nnc(-c3cccnc3)n2-c2ccccc2C)nc2cc(ccc12)C(O)=O InChI=1S/C25H22N6O2S/c1-3-30-21-11-10-17(24(32)33)13-19(21)27-22(30)15-34-25-29-28-23(18-8-6-12-26-14-18)31(25)20-9-5-4-7-16(20)2/h4-14H,3,15H2,1-2H3,(H,32,33) ILFXWPFVLVLRCY-UHFFFAOYSA-N 32068 1-ethyl-2-[[4-(2-methylphenyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanylmethyl]benzimidazole-5-carboxylic acid;hydrochloride::1-ethyl-2-[[[4-(2-methylphenyl)-5-(3-pyridinyl)-1,2,4-triazol-3-yl]thio]methyl]-5-benzimidazolecarboxylic acid;hydrochloride::1-ethyl-2-[[[4-(o-tolyl)-5-(3-pyridyl)-1,2,4-triazol-3-yl]thio]methyl]benzimidazole-5-carboxylic acid;hydrochloride::MLS000056095::SMR000067019::cid_6602956 Heat shock protein HSP 90-alpha Homo sapiens 3144.1 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32068&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 2123260 252615520 ZINC37868122 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76302 C[C@H]1CCC[C@H](O)CCCCCc2cc(O)cc(O)c2C(=O)O1 InChI=1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14+/m0/s1 DWTTZBARDOXEAM-GXTWGEPZSA-N 32073 (7R,11S)-11-methyl-7,15,17-tris(oxidanyl)-12-oxabicyclo[12.4.0]octadeca-1(14),15,17-trien-13-one::(7R,11S)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),15,17-trien-13-one::CHEMBL450613::MLS000081744::SMR000060050::Taleranol::Zearalanol::cid_2999413 Heat shock protein HSP 90-alpha Homo sapiens 27927.1 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32073&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 27J 4MG8,7AXH 2999413 252615525 CHEMBL450613 C14752 ZINC03831615 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76303 CCn1c(CSc2nnc3ccccn23)nc2cc(ccc12)C(O)=O InChI=1S/C17H15N5O2S/c1-2-21-13-7-6-11(16(23)24)9-12(13)18-15(21)10-25-17-20-19-14-5-3-4-8-22(14)17/h3-9H,2,10H2,1H3,(H,23,24) IMYAUPGHULTHRI-UHFFFAOYSA-N 32074 1-ethyl-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylsulfanylmethyl)benzimidazole-5-carboxylic acid::1-ethyl-2-[([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)methyl]-5-benzimidazolecarboxylic acid::1-ethyl-2-[([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)methyl]benzimidazole-5-carboxylic acid::MLS000058049::SMR000067059::cid_2123860 Heat shock protein HSP 90-alpha Homo sapiens >30000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32074&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 2123860 252615526 ZINC37868093 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76304 CCc1cc(-c2n[nH]cc2-c2ccc3OCOc3c2)c(O)cc1O InChI=1S/C18H16N2O4/c1-2-10-5-12(15(22)7-14(10)21)18-13(8-19-20-18)11-3-4-16-17(6-11)24-9-23-16/h3-8,21-22H,2,9H2,1H3,(H,19,20) JHMXKGMRRKUZPH-UHFFFAOYSA-N 32079 (6E)-6-[4-(1,3-benzodioxol-5-yl)-1,2-dihydropyrazol-3-ylidene]-4-ethyl-3-hydroxy-1-cyclohexa-2,4-dienone::(6E)-6-[4-(1,3-benzodioxol-5-yl)-1,2-dihydropyrazol-3-ylidene]-4-ethyl-3-hydroxycyclohexa-2,4-dien-1-one::(6E)-6-[4-(1,3-benzodioxol-5-yl)-1,2-dihydropyrazol-3-ylidene]-4-ethyl-3-oxidanyl-cyclohexa-2,4-dien-1-one::(6E)-6-[4-(1,3-benzodioxol-5-yl)-3-pyrazolin-3-ylidene]-4-ethyl-3-hydroxy-cyclohexa-2,4-dien-1-one::MLS000055606::SMR000060132::cid_5742573 Heat shock protein HSP 90-alpha Homo sapiens >30000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32079&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 5742573 252615531 ZINC18130036 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76305 Cn1ncnc2c1nc(=O)n(C)c2=O InChI=1S/C7H7N5O2/c1-11-6(13)4-5(10-7(11)14)12(2)9-3-8-4/h3H,1-2H3 SLGRAIAQIAUZAQ-UHFFFAOYSA-N 32102 1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione::1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione::1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-quinone::MLS000087831::SMR000024051::US9284299, PKF118-310::US9738628, Compound PKF118-310::cid_66541 Heat shock protein HSP 90-alpha Homo sapiens <1875 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32102&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search TOF 3PKX,3OUM,5JDY,5JE1 66541 252615554 C16789 ZINC00342245 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76306 Oc1ccc(cc1)-c1nc(cs1)-c1ccc(O)c(O)c1 InChI=1S/C15H11NO3S/c17-11-4-1-9(2-5-11)15-16-12(8-20-15)10-3-6-13(18)14(19)7-10/h1-8,17-19H FSQMZTBSNBWMOW-UHFFFAOYSA-N 32135 4-[4-(3,4-dihydroxyphenyl)-3H-1,3-thiazol-2-ylidene]cyclohexa-2,5-dien-1-one::4-[4-(3,4-dihydroxyphenyl)-3H-thiazol-2-ylidene]-1-cyclohexa-2,5-dienone::4-[4-(3,4-dihydroxyphenyl)-4-thiazolin-2-ylidene]cyclohexa-2,5-dien-1-one::4-[4-[3,4-bis(oxidanyl)phenyl]-3H-1,3-thiazol-2-ylidene]cyclohexa-2,5-dien-1-one::MLS000111214::SMR000107140::cid_5406370 Heat shock protein HSP 90-alpha Homo sapiens >30000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32135&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 5406370 252615587 ZINC13126612 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76307 COc1cc(NS(=O)(=O)c2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)c2ncccc2c1 InChI=1S/C16H12N4O7S/c1-27-12-7-10-3-2-6-17-16(10)13(9-12)18-28(25,26)15-5-4-11(19(21)22)8-14(15)20(23)24/h2-9,18H,1H3 QPQAKYTXPYXDJZ-UHFFFAOYSA-N 40733 N-(6-methoxy-8-quinolinyl)-2,4-dinitrobenzenesulfonamide::N-(6-methoxy-8-quinolyl)-2,4-dinitro-benzenesulfonamide::N-(6-methoxyquinolin-8-yl)-2,4-dinitro-benzenesulfonamide::N-(6-methoxyquinolin-8-yl)-2,4-dinitrobenzenesulfonamide::TG1-298-3::cid_16072224 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40733&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072224 252621550 ZINC35000856 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76308 COc1cc(N)c2ncccc2c1 InChI=1S/C10H10N2O/c1-13-8-5-7-3-2-4-12-10(7)9(11)6-8/h2-6H,11H2,1H3 YGGTVPCTAKYCSQ-UHFFFAOYSA-N 40734 (6-methoxy-8-quinolyl)amine::6-methoxy-8-quinolinamine::6-methoxyquinolin-8-amine::TG1-293-1::cid_7023 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40734&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 7023 252621551 ZINC00403451 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76309 COc1cc(NC(C)CCC[NH3+])c2ncccc2c1 InChI=1S/C15H21N3O/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14/h4,6,8-11,18H,3,5,7,16H2,1-2H3/p+1 INDBQLZJXZLFIT-UHFFFAOYSA-O 50149893 4-(6-Methoxy-quinolin-8-ylamino)-pentyl-ammonium::CHEMBL506::PRIMAQUINE Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149893&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 24848224 104037968 8405 CHEMBL506 C07627 ZINC01530863 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76310 COc1cc(NC(C)CCC[NH3+])c2ncccc2c1 InChI=1S/C15H21N3O/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14/h4,6,8-11,18H,3,5,7,16H2,1-2H3/p+1 INDBQLZJXZLFIT-UHFFFAOYSA-O 50149893 4-(6-Methoxy-quinolin-8-ylamino)-pentyl-ammonium::CHEMBL506::PRIMAQUINE Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149893&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 24848224 104037968 8405 CHEMBL506 C07627 ZINC01530863 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76311 Nc1ccc(O)c2ncccc12 InChI=1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2 YDEUKNRKEYICTH-UHFFFAOYSA-N 32142 5-amino-8-quinolinol::5-aminoquinolin-8-ol::5-azanylquinolin-8-ol::AS-0308-225::cid_416002 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32142&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 416002 252615593 ZINC00120515 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76312 Oc1cc(NS(=O)(=O)c2ccc(F)cc2)c2ncccc2c1 InChI=1S/C15H11FN2O3S/c16-11-3-5-13(6-4-11)22(20,21)18-14-9-12(19)8-10-2-1-7-17-15(10)14/h1-9,18-19H VIILSDIQZZYZGM-UHFFFAOYSA-N 32149 4-fluoranyl-N-(6-oxidanylquinolin-8-yl)benzenesulfonamide::4-fluoro-N-(6-hydroxy-8-quinolinyl)benzenesulfonamide::4-fluoro-N-(6-hydroxy-8-quinolyl)benzenesulfonamide::4-fluoro-N-(6-hydroxyquinolin-8-yl)benzenesulfonamide::TG2-97-3-2::cid_16072243 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32149&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072243 252615600 ZINC35000888 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76313 Oc1cc(NS(=O)(=O)c2ccc(F)c(c2)C#N)c2ncccc2c1 InChI=1S/C16H10FN3O3S/c17-14-4-3-13(7-11(14)9-18)24(22,23)20-15-8-12(21)6-10-2-1-5-19-16(10)15/h1-8,20-21H UNJIEMDMXPMENR-UHFFFAOYSA-N 32150 3-cyano-4-fluoranyl-N-(6-oxidanylquinolin-8-yl)benzenesulfonamide::3-cyano-4-fluoro-N-(6-hydroxy-8-quinolinyl)benzenesulfonamide::3-cyano-4-fluoro-N-(6-hydroxy-8-quinolyl)benzenesulfonamide::3-cyano-4-fluoro-N-(6-hydroxyquinolin-8-yl)benzenesulfonamide::TG2-97-3-1::cid_16072244 Heat shock protein HSP 90-alpha Homo sapiens 33845.8 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32150&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072244 252615601 ZINC35000890 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76314 Cc1ccc(cc1)S(=O)(=O)Nc1ccc(F)c(c1)-c1c2OCOc2ccc1O InChI=1S/C20H16FNO5S/c1-12-2-5-14(6-3-12)28(24,25)22-13-4-7-16(21)15(10-13)19-17(23)8-9-18-20(19)27-11-26-18/h2-10,22-23H,11H2,1H3 NSYWWSFCQSTAPB-UHFFFAOYSA-N 32151 N-[4-fluoranyl-3-(5-oxidanyl-1,3-benzodioxol-4-yl)phenyl]-4-methyl-benzenesulfonamide::N-[4-fluoro-3-(5-hydroxy-1,3-benzodioxol-4-yl)phenyl]-4-methyl-benzenesulfonamide::N-[4-fluoro-3-(5-hydroxy-1,3-benzodioxol-4-yl)phenyl]-4-methylbenzenesulfonamide::TG1-218-1::cid_16072245 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32151&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072245 252615602 ZINC35000892 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76315 CC(C)(C)OC(=O)Nc1cccc(NS(=O)(=O)c2cc(Cl)ccc2Cl)c1-c1ccccc1O InChI=1S/C23H22Cl2N2O5S/c1-23(2,3)32-22(29)26-17-8-6-9-18(21(17)15-7-4-5-10-19(15)28)27-33(30,31)20-13-14(24)11-12-16(20)25/h4-13,27-28H,1-3H3,(H,26,29) OYNDRFGHUYRMME-UHFFFAOYSA-N 32159 N-[3-[(2,5-dichlorophenyl)sulfonylamino]-2-(2-hydroxyphenyl)phenyl]carbamic acid tert-butyl ester::TG2-71-1::cid_16667754::tert-butyl N-[3-[(2,5-dichlorophenyl)sulfonylamino]-2-(2-hydroxyphenyl)phenyl]carbamate::tert-butyl N-[3-[[2,5-bis(chloranyl)phenyl]sulfonylamino]-2-(2-hydroxyphenyl)phenyl]carbamate Heat shock protein HSP 90-alpha Homo sapiens 48248.5 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32159&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16667754 252615610 ZINC37246100 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76316 Nc1ccc(NS(=O)(=O)c2cc(Cl)ccc2Cl)cc1-c1ccccc1O InChI=1S/C18H14Cl2N2O3S/c19-11-5-7-15(20)18(9-11)26(24,25)22-12-6-8-16(21)14(10-12)13-3-1-2-4-17(13)23/h1-10,22-23H,21H2 KDHXYGSAGGQFCL-UHFFFAOYSA-N 32160 N-[4-amino-3-(2-hydroxyphenyl)phenyl]-2,5-dichloro-benzenesulfonamide::N-[4-amino-3-(2-hydroxyphenyl)phenyl]-2,5-dichlorobenzenesulfonamide::N-[4-azanyl-3-(2-hydroxyphenyl)phenyl]-2,5-bis(chloranyl)benzenesulfonamide::TG2-71-2::cid_16072254 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32160&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072254 252615611 ZINC35000905 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76317 COc1ccc2OCOc2c1-c1cc(NS(=O)(=O)c2cc(Cl)ccc2Cl)ccc1N InChI=1S/C20H16Cl2N2O5S/c1-27-16-6-7-17-20(29-10-28-17)19(16)13-9-12(3-5-15(13)23)24-30(25,26)18-8-11(21)2-4-14(18)22/h2-9,24H,10,23H2,1H3 ANOZYKGBQODWDK-UHFFFAOYSA-N 32161 N-[4-amino-3-(5-methoxy-1,3-benzodioxol-4-yl)phenyl]-2,5-dichloro-benzenesulfonamide::N-[4-amino-3-(5-methoxy-1,3-benzodioxol-4-yl)phenyl]-2,5-dichlorobenzenesulfonamide::N-[4-azanyl-3-(5-methoxy-1,3-benzodioxol-4-yl)phenyl]-2,5-bis(chloranyl)benzenesulfonamide::TG2-77::cid_16072255 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32161&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072255 252615612 ZINC35000907 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76318 Nc1ccc(NS(=O)(=O)c2ccccc2[N+]([O-])=O)cc1-c1ccccc1O InChI=1S/C18H15N3O5S/c19-15-10-9-12(11-14(15)13-5-1-3-7-17(13)22)20-27(25,26)18-8-4-2-6-16(18)21(23)24/h1-11,20,22H,19H2 HTYNNBCSSJADSK-UHFFFAOYSA-N 32162 N-[4-amino-3-(2-hydroxyphenyl)phenyl]-2-nitro-benzenesulfonamide::N-[4-amino-3-(2-hydroxyphenyl)phenyl]-2-nitrobenzenesulfonamide::N-[4-azanyl-3-(2-hydroxyphenyl)phenyl]-2-nitro-benzenesulfonamide::TG2-80-1::cid_16072256 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32162&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072256 252615613 ZINC35000908 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76319 Nc1ccc(NS(=O)(=O)c2cccc(c2)[N+]([O-])=O)cc1-c1ccccc1O InChI=1S/C18H15N3O5S/c19-17-9-8-12(10-16(17)15-6-1-2-7-18(15)22)20-27(25,26)14-5-3-4-13(11-14)21(23)24/h1-11,20,22H,19H2 LYRIMUKQWZNDHJ-UHFFFAOYSA-N 32163 N-[4-amino-3-(2-hydroxyphenyl)phenyl]-3-nitro-benzenesulfonamide::N-[4-amino-3-(2-hydroxyphenyl)phenyl]-3-nitrobenzenesulfonamide::N-[4-azanyl-3-(2-hydroxyphenyl)phenyl]-3-nitro-benzenesulfonamide::TG2-80-2::cid_16072257 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32163&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072257 252615614 ZINC35000910 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76320 Nc1ccc(NS(=O)(=O)c2ccccc2N)cc1-c1ccccc1O InChI=1S/C18H17N3O3S/c19-15-10-9-12(11-14(15)13-5-1-3-7-17(13)22)21-25(23,24)18-8-4-2-6-16(18)20/h1-11,21-22H,19-20H2 JCCZRYLWESFGSU-UHFFFAOYSA-N 32164 2-amino-N-[4-amino-3-(2-hydroxyphenyl)phenyl]benzenesulfonamide::2-azanyl-N-[4-azanyl-3-(2-hydroxyphenyl)phenyl]benzenesulfonamide::TG2-84-1::cid_16072258 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32164&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072258 252615615 ZINC35000912 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76321 Nc1cccc(c1)S(=O)(=O)Nc1ccc(N)c(c1)-c1ccccc1O InChI=1S/C18H17N3O3S/c19-12-4-3-5-14(10-12)25(23,24)21-13-8-9-17(20)16(11-13)15-6-1-2-7-18(15)22/h1-11,21-22H,19-20H2 WJKGWHKLHMNZRK-UHFFFAOYSA-N 32165 3-amino-N-[4-amino-3-(2-hydroxyphenyl)phenyl]benzenesulfonamide::3-azanyl-N-[4-azanyl-3-(2-hydroxyphenyl)phenyl]benzenesulfonamide::TG2-84-2::cid_16072259 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32165&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072259 252615616 ZINC35000913 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76322 COc1ccc2OCOc2c1-c1cc(NS(=O)(=O)c2cccc(c2)[N+]([O-])=O)ccc1N InChI=1S/C20H17N3O7S/c1-28-17-7-8-18-20(30-11-29-18)19(17)15-9-12(5-6-16(15)21)22-31(26,27)14-4-2-3-13(10-14)23(24)25/h2-10,22H,11,21H2,1H3 AVVYRTOLEBREDE-UHFFFAOYSA-N 32166 N-[4-amino-3-(5-methoxy-1,3-benzodioxol-4-yl)phenyl]-3-nitro-benzenesulfonamide::N-[4-amino-3-(5-methoxy-1,3-benzodioxol-4-yl)phenyl]-3-nitrobenzenesulfonamide::N-[4-azanyl-3-(5-methoxy-1,3-benzodioxol-4-yl)phenyl]-3-nitro-benzenesulfonamide::TG2-86-1::cid_16072260 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32166&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072260 252615617 ZINC35000915 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76323 COc1ccc2OCOc2c1-c1cc(NS(=O)(=O)c2ccc(C)cc2)ccc1N InChI=1S/C21H20N2O5S/c1-13-3-6-15(7-4-13)29(24,25)23-14-5-8-17(22)16(11-14)20-18(26-2)9-10-19-21(20)28-12-27-19/h3-11,23H,12,22H2,1-2H3 GMEKNNJZOGMAFC-UHFFFAOYSA-N 32167 N-[4-amino-3-(5-methoxy-1,3-benzodioxol-4-yl)phenyl]-4-methyl-benzenesulfonamide::N-[4-amino-3-(5-methoxy-1,3-benzodioxol-4-yl)phenyl]-4-methylbenzenesulfonamide::N-[4-azanyl-3-(5-methoxy-1,3-benzodioxol-4-yl)phenyl]-4-methyl-benzenesulfonamide::TG2-86-2::cid_16072261 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32167&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072261 252615618 ZINC35000916 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76324 Oc1ccccc1-c1cc(NS(=O)(=O)c2cc(Cl)ccc2Cl)ccc1O InChI=1S/C18H13Cl2NO4S/c19-11-5-7-15(20)18(9-11)26(24,25)21-12-6-8-17(23)14(10-12)13-3-1-2-4-16(13)22/h1-10,21-23H GLGODKFZFFZDDG-UHFFFAOYSA-N 32168 2,5-bis(chloranyl)-N-[3-(2-hydroxyphenyl)-4-oxidanyl-phenyl]benzenesulfonamide::2,5-dichloro-N-[4-hydroxy-3-(2-hydroxyphenyl)phenyl]benzenesulfonamide::TG2-90-1::cid_16072262 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32168&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072262 252615619 ZINC35000918 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76325 Cc1ccc(cc1)S(=O)(=O)Nc1ccc(O)c(c1)-c1ccccc1O InChI=1S/C19H17NO4S/c1-13-6-9-15(10-7-13)25(23,24)20-14-8-11-19(22)17(12-14)16-4-2-3-5-18(16)21/h2-12,20-22H,1H3 UOVMGPDKURISLV-UHFFFAOYSA-N 32169 N-[3-(2-hydroxyphenyl)-4-oxidanyl-phenyl]-4-methyl-benzenesulfonamide::N-[4-hydroxy-3-(2-hydroxyphenyl)phenyl]-4-methyl-benzenesulfonamide::N-[4-hydroxy-3-(2-hydroxyphenyl)phenyl]-4-methylbenzenesulfonamide::TG2-90-2::cid_16072263 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32169&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072263 252615620 ZINC35000920 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76326 COc1ccc(cc1OC)S(=O)(=O)Nc1ccc(O)c(c1)-c1ccccc1O InChI=1S/C20H19NO6S/c1-26-19-10-8-14(12-20(19)27-2)28(24,25)21-13-7-9-18(23)16(11-13)15-5-3-4-6-17(15)22/h3-12,21-23H,1-2H3 DFXRQICUKIMCRB-UHFFFAOYSA-N 32170 N-[3-(2-hydroxyphenyl)-4-oxidanyl-phenyl]-3,4-dimethoxy-benzenesulfonamide::N-[4-hydroxy-3-(2-hydroxyphenyl)phenyl]-3,4-dimethoxy-benzenesulfonamide::N-[4-hydroxy-3-(2-hydroxyphenyl)phenyl]-3,4-dimethoxybenzenesulfonamide::TG2-91-1::cid_16072264 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32170&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072264 252615621 ZINC35000921 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76327 Oc1ccccc1-c1cc(NS(=O)(=O)c2cccc(c2)[N+]([O-])=O)ccc1O InChI=1S/C18H14N2O6S/c21-17-7-2-1-6-15(17)16-10-12(8-9-18(16)22)19-27(25,26)14-5-3-4-13(11-14)20(23)24/h1-11,19,21-22H NJZLTPHJBPAOKP-UHFFFAOYSA-N 32171 N-[3-(2-hydroxyphenyl)-4-oxidanyl-phenyl]-3-nitro-benzenesulfonamide::N-[4-hydroxy-3-(2-hydroxyphenyl)phenyl]-3-nitro-benzenesulfonamide::N-[4-hydroxy-3-(2-hydroxyphenyl)phenyl]-3-nitrobenzenesulfonamide::TG2-91-2::cid_16072265 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32171&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072265 252615622 ZINC35000923 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76328 COc1ccc2OCOc2c1-c1cc(NS(=O)(=O)c2cccc(N)c2)ccc1N InChI=1S/C20H19N3O5S/c1-26-17-7-8-18-20(28-11-27-18)19(17)15-10-13(5-6-16(15)22)23-29(24,25)14-4-2-3-12(21)9-14/h2-10,23H,11,21-22H2,1H3 IRGORDWDXJELJQ-UHFFFAOYSA-N 32172 3-amino-N-[4-amino-3-(5-methoxy-1,3-benzodioxol-4-yl)phenyl]benzenesulfonamide::3-azanyl-N-[4-azanyl-3-(5-methoxy-1,3-benzodioxol-4-yl)phenyl]benzenesulfonamide::TG2-92::cid_16072266 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32172&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072266 252615623 ZINC35000925 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76329 Cc1ccc(cc1)S(=O)(=O)Nc1ccc(N)c(c1)-c1ccccc1O InChI=1S/C19H18N2O3S/c1-13-6-9-15(10-7-13)25(23,24)21-14-8-11-18(20)17(12-14)16-4-2-3-5-19(16)22/h2-12,21-22H,20H2,1H3 ZYYOQSXLANGODL-UHFFFAOYSA-N 32173 N-[4-amino-3-(2-hydroxyphenyl)phenyl]-4-methyl-benzenesulfonamide::N-[4-amino-3-(2-hydroxyphenyl)phenyl]-4-methylbenzenesulfonamide::N-[4-azanyl-3-(2-hydroxyphenyl)phenyl]-4-methyl-benzenesulfonamide::TG2-95-1::cid_16072267 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32173&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072267 252615624 ZINC35000927 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76330 COc1ccc(cc1OC)S(=O)(=O)Nc1ccc(N)c(c1)-c1ccccc1O InChI=1S/C20H20N2O5S/c1-26-19-10-8-14(12-20(19)27-2)28(24,25)22-13-7-9-17(21)16(11-13)15-5-3-4-6-18(15)23/h3-12,22-23H,21H2,1-2H3 AUCSWTZGPVKSAM-UHFFFAOYSA-N 32174 N-[4-amino-3-(2-hydroxyphenyl)phenyl]-3,4-dimethoxy-benzenesulfonamide::N-[4-amino-3-(2-hydroxyphenyl)phenyl]-3,4-dimethoxybenzenesulfonamide::N-[4-azanyl-3-(2-hydroxyphenyl)phenyl]-3,4-dimethoxy-benzenesulfonamide::TG2-95-2::cid_16072268 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32174&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072268 252615625 ZINC35000928 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76331 CCOc1ccc2ccccc2c1-c1cc(NS(=O)(=O)c2cc(Cl)ccc2Cl)ccc1NC(=O)OC(C)(C)C InChI=1S/C29H28Cl2N2O5S/c1-5-37-25-15-10-18-8-6-7-9-21(18)27(25)22-17-20(12-14-24(22)32-28(34)38-29(2,3)4)33-39(35,36)26-16-19(30)11-13-23(26)31/h6-17,33H,5H2,1-4H3,(H,32,34) MPWSTMOVEPBKOE-UHFFFAOYSA-N 32175 N-[4-[(2,5-dichlorophenyl)sulfonylamino]-2-(2-ethoxy-1-naphthalenyl)phenyl]carbamic acid tert-butyl ester::N-[4-[(2,5-dichlorophenyl)sulfonylamino]-2-(2-ethoxy-1-naphthyl)phenyl]carbamic acid tert-butyl ester::TG2-98-1-1::cid_16072269::tert-butyl N-[4-[(2,5-dichlorophenyl)sulfonylamino]-2-(2-ethoxynaphthalen-1-yl)phenyl]carbamate::tert-butyl N-[4-[[2,5-bis(chloranyl)phenyl]sulfonylamino]-2-(2-ethoxynaphthalen-1-yl)phenyl]carbamate Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32175&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072269 252615626 ZINC37246101 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76332 CCOc1ccc2ccccc2c1-c1cc(NS(=O)(=O)c2cc(Cl)ccc2Cl)ccc1N InChI=1S/C24H20Cl2N2O3S/c1-2-31-22-12-7-15-5-3-4-6-18(15)24(22)19-14-17(9-11-21(19)27)28-32(29,30)23-13-16(25)8-10-20(23)26/h3-14,28H,2,27H2,1H3 FANRGJYMFODVQJ-UHFFFAOYSA-N 32176 N-[4-amino-3-(2-ethoxy-1-naphthalenyl)phenyl]-2,5-dichlorobenzenesulfonamide::N-[4-amino-3-(2-ethoxy-1-naphthyl)phenyl]-2,5-dichloro-benzenesulfonamide::N-[4-amino-3-(2-ethoxynaphthalen-1-yl)phenyl]-2,5-dichlorobenzenesulfonamide::N-[4-azanyl-3-(2-ethoxynaphthalen-1-yl)phenyl]-2,5-bis(chloranyl)benzenesulfonamide::TG2-98-1-2::cid_16072270 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32176&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072270 252615627 ZINC35000930 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76333 CCOc1ccc2ccccc2c1-c1cc(NS(=O)(=O)c2ccc(C)cc2)ccc1N InChI=1S/C25H24N2O3S/c1-3-30-24-15-10-18-6-4-5-7-21(18)25(24)22-16-19(11-14-23(22)26)27-31(28,29)20-12-8-17(2)9-13-20/h4-16,27H,3,26H2,1-2H3 XICMXLLBEAWGAU-UHFFFAOYSA-N 32177 N-[4-amino-3-(2-ethoxy-1-naphthalenyl)phenyl]-4-methylbenzenesulfonamide::N-[4-amino-3-(2-ethoxy-1-naphthyl)phenyl]-4-methyl-benzenesulfonamide::N-[4-amino-3-(2-ethoxynaphthalen-1-yl)phenyl]-4-methylbenzenesulfonamide::N-[4-azanyl-3-(2-ethoxynaphthalen-1-yl)phenyl]-4-methyl-benzenesulfonamide::TG2-98-2::cid_16072271 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32177&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072271 252615628 ZINC35000932 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76334 CCOc1ccc2ccccc2c1-c1cc(NS(=O)(=O)c2ccc(OC)c(OC)c2)ccc1N InChI=1S/C26H26N2O5S/c1-4-33-24-13-9-17-7-5-6-8-20(17)26(24)21-15-18(10-12-22(21)27)28-34(29,30)19-11-14-23(31-2)25(16-19)32-3/h5-16,28H,4,27H2,1-3H3 ZWPMBTDYZXOEAV-UHFFFAOYSA-N 32178 N-[4-amino-3-(2-ethoxy-1-naphthalenyl)phenyl]-3,4-dimethoxybenzenesulfonamide::N-[4-amino-3-(2-ethoxy-1-naphthyl)phenyl]-3,4-dimethoxy-benzenesulfonamide::N-[4-amino-3-(2-ethoxynaphthalen-1-yl)phenyl]-3,4-dimethoxybenzenesulfonamide::N-[4-azanyl-3-(2-ethoxynaphthalen-1-yl)phenyl]-3,4-dimethoxy-benzenesulfonamide::TG2-98-3::cid_16072272 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32178&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072272 252615629 ZINC35000934 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76335 Nc1cccc(c1)S(=O)(=O)Nc1ccc(O)c(c1)-c1ccccc1O InChI=1S/C18H16N2O4S/c19-12-4-3-5-14(10-12)25(23,24)20-13-8-9-18(22)16(11-13)15-6-1-2-7-17(15)21/h1-11,20-22H,19H2 NPANFVHAWOBQEB-UHFFFAOYSA-N 32179 3-amino-N-[4-hydroxy-3-(2-hydroxyphenyl)phenyl]benzenesulfonamide::3-azanyl-N-[3-(2-hydroxyphenyl)-4-oxidanyl-phenyl]benzenesulfonamide::TG2-99::cid_16072273 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32179&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072273 252615630 ZINC35000936 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76336 NCc1cc(ccc1F)S(=O)(=O)Nc1cc(O)cc2cccnc12 InChI=1S/C16H14FN3O3S/c17-14-4-3-13(7-11(14)9-18)24(22,23)20-15-8-12(21)6-10-2-1-5-19-16(10)15/h1-8,20-21H,9,18H2 PSNMYYQOTDSGQG-UHFFFAOYSA-N 32180 3-(aminomethyl)-4-fluoranyl-N-(6-oxidanylquinolin-8-yl)benzenesulfonamide::3-(aminomethyl)-4-fluoro-N-(6-hydroxy-8-quinolinyl)benzenesulfonamide::3-(aminomethyl)-4-fluoro-N-(6-hydroxy-8-quinolyl)benzenesulfonamide::3-(aminomethyl)-4-fluoro-N-(6-hydroxyquinolin-8-yl)benzenesulfonamide::TG2-56-1::cid_16072274 Heat shock protein HSP 90-alpha Homo sapiens 16099.8 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32180&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072274 252615631 ZINC35000938 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76337 COc1ccc(NS(=O)(=O)c2ccccc2)c(OC)c1 InChI=1S/C14H15NO4S/c1-18-11-8-9-13(14(10-11)19-2)15-20(16,17)12-6-4-3-5-7-12/h3-10,15H,1-2H3 HNHXWPQVOKUAMD-UHFFFAOYSA-N 32181 N-(2,4-dimethoxyphenyl)benzenesulfonamide::TG2-100-1::cid_711185 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32181&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 711185 252615632 ZINC00102657 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76338 Nc1ccc(NS(=O)(=O)c2ccccc2)c(O)c1 InChI=1S/C12H12N2O3S/c13-9-6-7-11(12(15)8-9)14-18(16,17)10-4-2-1-3-5-10/h1-8,14-15H,13H2 WGARESHTVLAADK-UHFFFAOYSA-N 32182 N-(4-amino-2-hydroxy-phenyl)benzenesulfonamide::N-(4-amino-2-hydroxyphenyl)benzenesulfonamide::N-(4-azanyl-2-oxidanyl-phenyl)benzenesulfonamide::TG2-100-2::cid_3608856 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32182&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 3608856 252615633 ZINC00396613 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76339 Oc1cc(ccc1NS(=O)(=O)c1ccccc1)[N+]([O-])=O InChI=1S/C12H10N2O5S/c15-12-8-9(14(16)17)6-7-11(12)13-20(18,19)10-4-2-1-3-5-10/h1-8,13,15H NJLNHUHLXNVVBG-UHFFFAOYSA-N 32183 N-(2-hydroxy-4-nitro-phenyl)benzenesulfonamide::N-(2-hydroxy-4-nitrophenyl)benzenesulfonamide::N-(4-nitro-2-oxidanyl-phenyl)benzenesulfonamide::TG2-100-3::cid_5225749 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32183&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 5225749 252615634 ZINC05279582 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76340 Oc1cc(Cl)ccc1NS(=O)(=O)c1ccccc1 InChI=1S/C12H10ClNO3S/c13-9-6-7-11(12(15)8-9)14-18(16,17)10-4-2-1-3-5-10/h1-8,14-15H RONKFMHPAFRXHH-UHFFFAOYSA-N 32184 CHEMBL209511::N-(4-chloranyl-2-oxidanyl-phenyl)benzenesulfonamide::N-(4-chloro-2-hydroxy-phenyl)benzenesulfonamide::N-(4-chloro-2-hydroxyphenyl)benzenesulfonamide::TG2-101-1::cid_800888 Heat shock protein HSP 90-alpha Homo sapiens >60000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32184&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 800888 252615635 CHEMBL209511 ZINC00307742 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76341 COc1cc(ccc1O)C1CC(N=N1)c1ccccc1O InChI=1S/C16H16N2O3/c1-21-16-8-10(6-7-15(16)20)12-9-13(18-17-12)11-4-2-3-5-14(11)19/h2-8,12-13,19-20H,9H2,1H3 KHERWPKMPPANRP-UHFFFAOYSA-N 32185 6-[5-(3-methoxy-4-oxidanyl-phenyl)pyrazolidin-3-ylidene]cyclohexa-2,4-dien-1-one::6-[5-(4-hydroxy-3-methoxy-phenyl)pyrazolidin-3-ylidene]cyclohexa-2,4-dien-1-one::6-[5-(4-hydroxy-3-methoxyphenyl)-3-pyrazolidinylidene]-1-cyclohexa-2,4-dienone::6-[5-(4-hydroxy-3-methoxyphenyl)pyrazolidin-3-ylidene]cyclohexa-2,4-dien-1-one::CHEMBL210638::TG2-101-2::cid_6790395 Heat shock protein HSP 90-alpha Homo sapiens 50970.5 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32185&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 91896143 252615636 CHEMBL210638 ZINC22242027 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76342 COc1ccc(cc1OC)C1CC(N=N1)c1ccccc1O InChI=1S/C17H18N2O3/c1-21-16-8-7-11(9-17(16)22-2)13-10-14(19-18-13)12-5-3-4-6-15(12)20/h3-9,13-14,20H,10H2,1-2H3 ISBPSOSFHZEDOT-UHFFFAOYSA-N 32186 6-[5-(3,4-dimethoxyphenyl)-3-pyrazolidinylidene]-1-cyclohexa-2,4-dienone::6-[5-(3,4-dimethoxyphenyl)pyrazolidin-3-ylidene]cyclohexa-2,4-dien-1-one::TG2-101-3::cid_6807103 Heat shock protein HSP 90-alpha Homo sapiens 52349.4 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32186&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 91896144 252615637 ZINC00378872 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76343 COc1cc(NCCCC(C)N)c2nccc(Cl)c2c1 InChI=1S/C15H20ClN3O/c1-10(17)4-3-6-18-14-9-11(20-2)8-12-13(16)5-7-19-15(12)14/h5,7-10,18H,3-4,6,17H2,1-2H3 YJSWGARIHPHYKC-UHFFFAOYSA-N 32193 1-N-(4-chloro-6-methoxyquinolin-8-yl)pentane-1,4-diamine::4-aminopentyl-(4-chloro-6-methoxy-8-quinolyl)amine::N1-(4-chloranyl-6-methoxy-quinolin-8-yl)pentane-1,4-diamine::N1-(4-chloro-6-methoxy-8-quinolinyl)pentane-1,4-diamine::TG2-26-2::cid_16072277 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32193&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072277 252615643 ZINC35000944 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76344 Oc1ccc2OCOc2c1-c1cc(NS(=O)(=O)c2ccc(F)c(c2)C#N)ccc1F InChI=1S/C20H12F2N2O5S/c21-15-4-2-13(7-11(15)9-23)30(26,27)24-12-1-3-16(22)14(8-12)19-17(25)5-6-18-20(19)29-10-28-18/h1-8,24-25H,10H2 WXAGWZYGCQDYDM-UHFFFAOYSA-N 32194 3-cyano-4-fluoranyl-N-[4-fluoranyl-3-(5-oxidanyl-1,3-benzodioxol-4-yl)phenyl]benzenesulfonamide::3-cyano-4-fluoro-N-[4-fluoro-3-(5-hydroxy-1,3-benzodioxol-4-yl)phenyl]benzenesulfonamide::TG1-268-1::cid_16072278 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32194&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072278 252615644 ZINC35000946 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76345 Oc1ccc2OCOc2c1-c1cc(NS(=O)(=O)c2ccc(Cl)c(c2)[N+]([O-])=O)ccc1F InChI=1S/C19H12ClFN2O7S/c20-13-3-2-11(8-15(13)23(25)26)31(27,28)22-10-1-4-14(21)12(7-10)18-16(24)5-6-17-19(18)30-9-29-17/h1-8,22,24H,9H2 LRPKMIVRODZTOZ-UHFFFAOYSA-N 32195 4-chloranyl-N-[4-fluoranyl-3-(5-oxidanyl-1,3-benzodioxol-4-yl)phenyl]-3-nitro-benzenesulfonamide::4-chloro-N-[4-fluoro-3-(5-hydroxy-1,3-benzodioxol-4-yl)phenyl]-3-nitro-benzenesulfonamide::4-chloro-N-[4-fluoro-3-(5-hydroxy-1,3-benzodioxol-4-yl)phenyl]-3-nitrobenzenesulfonamide::TG1-218-2::cid_16072279 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32195&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 16072279 252615645 ZINC35000948 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76346 Nc1cccc2cc(O)ccc12 InChI=1S/C10H9NO/c11-10-3-1-2-7-6-8(12)4-5-9(7)10/h1-6,12H,11H2 FSBRKZMSECKELY-UHFFFAOYSA-N 32199 5-amino-2-naphthalenol::5-amino-2-naphthol::5-aminonaphthalen-2-ol::5-azanylnaphthalen-2-ol::cid_6865 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32199&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 6865 252615649 ZINC01672948 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76347 CC(C)NCCCC(C)Nc1cc(O)cc2cccnc12 InChI=1S/C17H25N3O/c1-12(2)18-8-4-6-13(3)20-16-11-15(21)10-14-7-5-9-19-17(14)16/h5,7,9-13,18,20-21H,4,6,8H2,1-3H3 BQXVFZVEBYAYEJ-UHFFFAOYSA-N 32201 8-[5-(propan-2-ylamino)pentan-2-ylamino]-6-quinolinol::8-[5-(propan-2-ylamino)pentan-2-ylamino]quinolin-6-ol::8-[[4-(isopropylamino)-1-methyl-butyl]amino]quinolin-6-ol::cid_245089 Heat shock protein HSP 90-alpha Homo sapiens >10000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32201&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 245089 252615651 ZINC40953977 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76348 CC(CCN(C)C)Nc1cc(O)cc2cccnc12 InChI=1S/C15H21N3O/c1-11(6-8-18(2)3)17-14-10-13(19)9-12-5-4-7-16-15(12)14/h4-5,7,9-11,17,19H,6,8H2,1-3H3 BSFODEXXVBBYOC-UHFFFAOYSA-N 32202 8-[4-(dimethylamino)butan-2-ylamino]-6-quinolinol::8-[4-(dimethylamino)butan-2-ylamino]quinolin-6-ol::8-[[3-(dimethylamino)-1-methyl-propyl]amino]quinolin-6-ol::cid_101745 Heat shock protein HSP 90-alpha Homo sapiens >10000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32202&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 101745 252615652 ZINC02041666 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76349 CCN(CC)CC(O)c1ccnc2c(O)cccc12 InChI=1S/C15H20N2O2/c1-3-17(4-2)10-14(19)11-8-9-16-15-12(11)6-5-7-13(15)18/h5-9,14,18-19H,3-4,10H2,1-2H3 MTNZAVIBHKMWPO-UHFFFAOYSA-N 32204 4-[2-(diethylamino)-1-hydroxy-ethyl]quinolin-8-ol::4-[2-(diethylamino)-1-hydroxyethyl]-8-quinolinol::4-[2-(diethylamino)-1-hydroxyethyl]quinolin-8-ol::4-[2-(diethylamino)-1-oxidanyl-ethyl]quinolin-8-ol::cid_274252 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32204&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 274252 252615654 ZINC13283287 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76350 Oc1cc([N+]([O-])=O)c2ncccc2c1 InChI=1S/C9H6N2O3/c12-7-4-6-2-1-3-10-9(6)8(5-7)11(13)14/h1-5,12H AZDVQVFOHUFHOP-UHFFFAOYSA-N 32207 8-nitro-6-quinolinol::8-nitroquinolin-6-ol::cid_226259 Heat shock protein HSP 90-alpha Homo sapiens >10000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32207&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 226259 252615656 ZINC01747022 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76351 Cc1[nH]c2c(N)cccc2c1C InChI=1S/C10H12N2/c1-6-7(2)12-10-8(6)4-3-5-9(10)11/h3-5,12H,11H2,1-2H3 SRBIHKSWFZJZFZ-UHFFFAOYSA-N 32209 (2,3-dimethyl-1H-indol-7-yl)amine::2,3-dimethyl-1H-indol-7-amine::cid_59003 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32209&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 59003 252615657 73398 ZINC01574107 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76352 Nc1cc2C(=O)c3ccccc3C(=O)c2c(O)c1O InChI=1S/C14H9NO4/c15-9-5-8-10(14(19)13(9)18)12(17)7-4-2-1-3-6(7)11(8)16/h1-5,18-19H,15H2 YLFWHISGXDKCIT-UHFFFAOYSA-N 32214 3-amino-1,2-dihydroxy-9,10-anthraquinone::3-amino-1,2-dihydroxyanthracene-9,10-dione::3-azanyl-1,2-bis(oxidanyl)anthracene-9,10-dione::cid_95861 Heat shock protein HSP 90-alpha Homo sapiens >10000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32214&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 95861 252615662 ZINC04522753 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76353 Nc1ccc(Nc2nc3ccccc3s2)c(O)c1 InChI=1S/C13H11N3OS/c14-8-5-6-9(11(17)7-8)15-13-16-10-3-1-2-4-12(10)18-13/h1-7,17H,14H2,(H,15,16) XFJMZTVKNAGMBR-UHFFFAOYSA-N 32217 5-amino-2-(1,3-benzothiazol-2-ylamino)phenol::5-azanyl-2-(1,3-benzothiazol-2-ylamino)phenol::cid_274134 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32217&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 274134 252615665 ZINC01709585 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76354 NCCCCCNc1cc(O)cc2cccnc12 InChI=1S/C14H19N3O/c15-6-2-1-3-7-16-13-10-12(18)9-11-5-4-8-17-14(11)13/h4-5,8-10,16,18H,1-3,6-7,15H2 WNRGIRYGYJNKOE-UHFFFAOYSA-N 32219 8-(5-aminopentylamino)-6-quinolinol::8-(5-aminopentylamino)quinolin-6-ol::8-(5-azanylpentylamino)quinolin-6-ol::cid_245091 Heat shock protein HSP 90-alpha Homo sapiens >10000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32219&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 245091 252615667 ZINC01687529 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76355 CC(C)NCCCCCNc1cc(O)cc2cccnc12 InChI=1S/C17H25N3O/c1-13(2)18-8-4-3-5-9-19-16-12-15(21)11-14-7-6-10-20-17(14)16/h6-7,10-13,18-19,21H,3-5,8-9H2,1-2H3 FCQZEZCNARMPGO-UHFFFAOYSA-N 32220 8-[5-(isopropylamino)pentylamino]quinolin-6-ol::8-[5-(propan-2-ylamino)pentylamino]-6-quinolinol::8-[5-(propan-2-ylamino)pentylamino]quinolin-6-ol::cid_408620 Heat shock protein HSP 90-alpha Homo sapiens >10000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32220&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 408620 252615668 ZINC01653205 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76356 Nc1cc(N)c2cccnc2c1O InChI=1S/C9H9N3O/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H,10-11H2 LZKZQHIHBPJQIL-UHFFFAOYSA-N 32221 5,7-bis(azanyl)quinolin-8-ol::5,7-diamino-8-quinolinol::5,7-diaminoquinolin-8-ol::cid_416003 Heat shock protein HSP 90-alpha Homo sapiens >10000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32221&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 416003 252615669 ZINC13283990 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76357 Nc1ccc(O)c2ncccc12 InChI=1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2 YDEUKNRKEYICTH-UHFFFAOYSA-N 32142 5-amino-8-quinolinol::5-aminoquinolin-8-ol::5-azanylquinolin-8-ol::AS-0308-225::cid_416002 Heat shock protein HSP 90-alpha Homo sapiens >10000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32142&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 416002 252615593 ZINC00120515 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76358 Nc1cc2ccccc2c(O)c1O InChI=1S/C10H9NO2/c11-8-5-6-3-1-2-4-7(6)9(12)10(8)13/h1-5,12-13H,11H2 AWYGNCJFNAYWMV-UHFFFAOYSA-N 32223 3-aminonaphthalene-1,2-diol::3-azanylnaphthalene-1,2-diol::cid_437034 Heat shock protein HSP 90-alpha Homo sapiens >10000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32223&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 437034 252615670 ZINC01599710 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76359 CCN(CC)CCCNc1cc(OC)c(Nc2ccccc2)c2cccnc12 InChI=1S/C23H30N4O/c1-4-27(5-2)16-10-15-24-20-17-21(28-3)23(19-13-9-14-25-22(19)20)26-18-11-7-6-8-12-18/h6-9,11-14,17,24,26H,4-5,10,15-16H2,1-3H3 FXMYAFICWADZRR-UHFFFAOYSA-N 40735 3-[(5-anilino-6-methoxy-8-quinolyl)amino]propyl-diethyl-amine::8-N-[3-(diethylamino)propyl]-6-methoxy-5-N-phenylquinoline-5,8-diamine::N8-[3-(diethylamino)propyl]-6-methoxy-N5-phenyl-quinoline-5,8-diamine::N8-[3-(diethylamino)propyl]-6-methoxy-N5-phenylquinoline-5,8-diamine::cid_220612 Heat shock protein HSP 90-alpha Homo sapiens >10000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40735&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 220612 252621552 ZINC01666870 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76360 COc1cc(NCCN(CC(C)C)CC(C)C)c2ncccc2c1 InChI=1S/C20H31N3O/c1-15(2)13-23(14-16(3)4)10-9-21-19-12-18(24-5)11-17-7-6-8-22-20(17)19/h6-8,11-12,15-16,21H,9-10,13-14H2,1-5H3 GUYTUSFKHTZPST-UHFFFAOYSA-N 32255 N-(6-methoxy-8-quinolinyl)-N',N'-bis(2-methylpropyl)ethane-1,2-diamine::N-(6-methoxyquinolin-8-yl)-N',N'-bis(2-methylpropyl)ethane-1,2-diamine::cid_407561::diisobutyl-[2-[(6-methoxy-8-quinolyl)amino]ethyl]amine Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32255&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 407561 252615701 ZINC01683572 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76361 COc1cc(NC(C)CCCNC(C)C)c2ncccc2c1OC InChI=1S/C19H29N3O2/c1-13(2)20-10-6-8-14(3)22-16-12-17(23-4)19(24-5)15-9-7-11-21-18(15)16/h7,9,11-14,20,22H,6,8,10H2,1-5H3 KSJAKLHPKINFJD-UHFFFAOYSA-N 40736 (5,6-dimethoxy-8-quinolyl)-[4-(isopropylamino)-1-methyl-butyl]amine;oxalic acid::4-N-(5,6-dimethoxyquinolin-8-yl)-1-N-propan-2-ylpentane-1,4-diamine;oxalic acid::N4-(5,6-dimethoxy-8-quinolinyl)-N1-propan-2-ylpentane-1,4-diamine;oxalic acid::N4-(5,6-dimethoxyquinolin-8-yl)-N1-propan-2-yl-pentane-1,4-diamine;ethanedioic acid::cid_224641 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40736&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 224642 252621553 ZINC40935582 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76362 COc1cc(NCCCN(CC(C)C)CC(C)C)c2ncccc2c1Cl InChI=1S/C21H32ClN3O/c1-15(2)13-25(14-16(3)4)11-7-10-23-18-12-19(26-5)20(22)17-8-6-9-24-21(17)18/h6,8-9,12,15-16,23H,7,10-11,13-14H2,1-5H3 FCGCFISCWZEHHG-UHFFFAOYSA-N 40737 3-[(5-chloro-6-methoxy-8-quinolyl)amino]propyl-diisobutyl-amine::N-(5-chloranyl-6-methoxy-quinolin-8-yl)-N',N'-bis(2-methylpropyl)propane-1,3-diamine::N-(5-chloro-6-methoxy-8-quinolinyl)-N',N'-bis(2-methylpropyl)propane-1,3-diamine::N-(5-chloro-6-methoxyquinolin-8-yl)-N',N'-bis(2-methylpropyl)propane-1,3-diamine::cid_408492 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40737&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 408492 252621554 ZINC01591923 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76363 COc1cc(NCCCCN)c2ncccc2c1 InChI=1S/C14H19N3O/c1-18-12-9-11-5-4-8-17-14(11)13(10-12)16-7-3-2-6-15/h4-5,8-10,16H,2-3,6-7,15H2,1H3 JVMFTXBPCRUPLQ-UHFFFAOYSA-N 40738 4-aminobutyl-(6-methoxy-8-quinolyl)amine::N'-(6-methoxy-8-quinolinyl)butane-1,4-diamine::N'-(6-methoxyquinolin-8-yl)butane-1,4-diamine::cid_231916 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40738&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 231916 252621555 ZINC01646656 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76364 CCN(CC)CCCC(C)Nc1cc(O)cc2cccnc12 InChI=1S/C18H27N3O/c1-4-21(5-2)11-7-8-14(3)20-17-13-16(22)12-15-9-6-10-19-18(15)17/h6,9-10,12-14,20,22H,4-5,7-8,11H2,1-3H3 XVRGMUYTMLBHEJ-UHFFFAOYSA-N 40739 8-[5-(diethylamino)pentan-2-ylamino]-6-quinolinol::8-[5-(diethylamino)pentan-2-ylamino]quinolin-6-ol::8-[[4-(diethylamino)-1-methyl-butyl]amino]quinolin-6-ol::cid_414096 Heat shock protein HSP 90-alpha Homo sapiens >10000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40739&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 414096 252621556 ZINC05839654 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76365 CCC(C)NCCNc1cc(OC)cc2cccnc12 InChI=1S/C16H23N3O/c1-4-12(2)17-8-9-18-15-11-14(20-3)10-13-6-5-7-19-16(13)15/h5-7,10-12,17-18H,4,8-9H2,1-3H3 VAQXHINHDXOSSE-UHFFFAOYSA-N 32256 (6-methoxy-8-quinolyl)-[2-(sec-butylamino)ethyl]amine::N'-butan-2-yl-N-(6-methoxy-8-quinolinyl)ethane-1,2-diamine::N'-butan-2-yl-N-(6-methoxyquinolin-8-yl)ethane-1,2-diamine::cid_410584 Heat shock protein HSP 90-alpha Homo sapiens >10000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32256&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 410584 252615702 ZINC05846395 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76366 CCN(CC)CCCNc1cc(OC)cc2ccc(OC)nc12 InChI=1S/C18H27N3O2/c1-5-21(6-2)11-7-10-19-16-13-15(22-3)12-14-8-9-17(23-4)20-18(14)16/h8-9,12-13,19H,5-7,10-11H2,1-4H3 LZPCPSXNCLLWIZ-UHFFFAOYSA-N 40740 3-[(2,6-dimethoxy-8-quinolyl)amino]propyl-diethyl-amine::N-(2,6-dimethoxy-8-quinolinyl)-N',N'-diethylpropane-1,3-diamine::N-(2,6-dimethoxyquinolin-8-yl)-N',N'-diethyl-propane-1,3-diamine::N-(2,6-dimethoxyquinolin-8-yl)-N',N'-diethylpropane-1,3-diamine::cid_408413 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40740&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 408413 252621557 ZINC01873652 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76367 COc1cc(NCC(O)CN(CC(C)C)CC(C)C)c2nc(C)ccc2c1 InChI=1S/C22H35N3O2/c1-15(2)12-25(13-16(3)4)14-19(26)11-23-21-10-20(27-6)9-18-8-7-17(5)24-22(18)21/h7-10,15-16,19,23,26H,11-14H2,1-6H3 VPPTWHKMIRXDDL-UHFFFAOYSA-N 32257 1-(diisobutylamino)-3-[(6-methoxy-2-methyl-8-quinolyl)amino]propan-2-ol::1-[bis(2-methylpropyl)amino]-3-[(6-methoxy-2-methyl-8-quinolinyl)amino]-2-propanol::1-[bis(2-methylpropyl)amino]-3-[(6-methoxy-2-methyl-quinolin-8-yl)amino]propan-2-ol::1-[bis(2-methylpropyl)amino]-3-[(6-methoxy-2-methylquinolin-8-yl)amino]propan-2-ol::cid_410560 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32257&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 410560 252615703 ZINC05931180 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76368 Nc1cc(O)cc2cccnc12 InChI=1S/C9H8N2O/c10-8-5-7(12)4-6-2-1-3-11-9(6)8/h1-5,12H,10H2 XSAFKWKVRFZBMP-UHFFFAOYSA-N 40741 8-amino-6-quinolinol::8-aminoquinolin-6-ol::8-azanylquinolin-6-ol::cid_244284 Heat shock protein HSP 90-alpha Homo sapiens <625 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40741&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 244284 252621558 ZINC13286715 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76369 CCC(CC)NCCCNc1cc(OC)cc2cccnc12 InChI=1S/C18H27N3O/c1-4-15(5-2)19-10-7-11-20-17-13-16(22-3)12-14-8-6-9-21-18(14)17/h6,8-9,12-13,15,19-20H,4-5,7,10-11H2,1-3H3 QMRJGRKVDMHYJG-UHFFFAOYSA-N 40742 1-ethylpropyl-[3-[(6-methoxy-8-quinolyl)amino]propyl]amine::N-(6-methoxy-8-quinolinyl)-N'-pentan-3-ylpropane-1,3-diamine::N-(6-methoxyquinolin-8-yl)-N'-pentan-3-yl-propane-1,3-diamine::N-(6-methoxyquinolin-8-yl)-N'-pentan-3-ylpropane-1,3-diamine::cid_414229 Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40742&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 414229 252621559 ZINC01687524 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76370 COc1cc(NC(C)CCCNC(C)C)c2ncccc2c1 InChI=1S/C18H27N3O/c1-13(2)19-9-5-7-14(3)21-17-12-16(22-4)11-15-8-6-10-20-18(15)17/h6,8,10-14,19,21H,5,7,9H2,1-4H3 FXVNYPZBTGPKQO-UHFFFAOYSA-N 40743 4-N-(6-methoxyquinolin-8-yl)-1-N-propan-2-ylpentane-1,4-diamine::N4-(6-methoxy-8-quinolinyl)-N1-propan-2-ylpentane-1,4-diamine::N4-(6-methoxyquinolin-8-yl)-N1-propan-2-yl-pentane-1,4-diamine::cid_98196::isopropyl-[4-[(6-methoxy-8-quinolyl)amino]pentyl]amine Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40743&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 98196 252621560 ZINC40933449 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76371 COc1ccc(Oc2c(OC)cc(NCCCCCNC(C)C)c3ncccc23)cc1 InChI=1S/C25H33N3O3/c1-18(2)26-14-6-5-7-15-27-22-17-23(30-4)25(21-9-8-16-28-24(21)22)31-20-12-10-19(29-3)11-13-20/h8-13,16-18,26-27H,5-7,14-15H2,1-4H3 QWKGZWUCKIOVBG-UHFFFAOYSA-N 40744 N-[6-methoxy-5-(4-methoxyphenoxy)-8-quinolinyl]-N'-propan-2-ylpentane-1,5-diamine::N-[6-methoxy-5-(4-methoxyphenoxy)quinolin-8-yl]-N'-propan-2-yl-pentane-1,5-diamine::N-[6-methoxy-5-(4-methoxyphenoxy)quinolin-8-yl]-N'-propan-2-ylpentane-1,5-diamine::cid_436997::isopropyl-[5-[[6-methoxy-5-(4-methoxyphenoxy)-8-quinolyl]amino]pentyl]amine Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40744&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 436997 252621561 ZINC01599092 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5 76372 CCCC(C)N(CC)CCNc1cc(OC)cc2cccnc12 InChI=1S/C19H29N3O/c1-5-8-15(3)22(6-2)12-11-20-18-14-17(23-4)13-16-9-7-10-21-19(16)18/h7,9-10,13-15,20H,5-6,8,11-12H2,1-4H3 OFRCZWKTAGPGSE-UHFFFAOYSA-N 32258 N'-ethyl-N-(6-methoxy-8-quinolinyl)-N'-pentan-2-ylethane-1,2-diamine::N'-ethyl-N-(6-methoxyquinolin-8-yl)-N'-pentan-2-yl-ethane-1,2-diamine::N'-ethyl-N-(6-methoxyquinolin-8-yl)-N'-pentan-2-ylethane-1,2-diamine::cid_410589::ethyl-[2-[(6-methoxy-8-quinolyl)amino]ethyl]-(1-methylbutyl)amine Heat shock protein HSP 90-alpha Homo sapiens >50000 PubChem 10.7270/Q25M643N aid754 PubChem, PC 8/6/2007 5/6/2011 Emory University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2092&target=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32258&enzyme=Heat+shock+protein+HSP+90-alpha&column=ki&startPg=0&Increment=50&submit=Search 410589 252615704 ZINC05839073 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 1OSF,1UY6,1UY7,1UY8,1UY9,1UYC,1UYD,1UYE,1UYF,1UYG,1UYH,1UYK,1UYL,2BSM,2BT0,2BYH,2BYI,2BZ5,2FWY,2FWZ,2H55,2QFO,2QG0,2UWD,2VCI,2VCJ,2WI1,2WI2,2WI3,2WI4,2WI5,2WI6,2WI7,2XAB,2XDK,2XDL,2XDS,2XDX,2XHR,2XHT,2XJX,2XK2,2YE2,2YE3,2YE4,2YE5,2YE6,2YE9,2YEA,2YEB,2YEC,2YED,2YEF,2YEG,2YEH,2YI0,2YI5,2YI6,2YI7,3B24,3B25,3B26,3B27,3B28,3D0B,3EKO,3EKR,3FT5,3FT8,3HEK,3HHU,3HYY,3HYZ,3HZ1,3HZ5,3INW,3INX,3K98,3K99,3MNR,3O0I,3PRY,3Q6M,3Q6N,3QDD,3R4M,3R4N,3R4O,3R4P,3RLP,3RLQ,3RLR,3T0H,3T0Z,3T10,3T1K,3T2S,3TUH,3VHA,3VHC,3VHD,3WHA,3WQ9,4AWO,4AWP,4AWQ,4B7P,4BQG,4BQJ,4CWF,4CWN,4CWO,4CWP,4CWQ,4CWR,4CWS,4CWT,4EEH,4EFT,4EFU,4EGH,4EGI,4EGK,4FCP,4FCQ,4FCR,4HY6,4JQL,4L8Z,4L90,4L91,4L93,4L94,4LWE,4LWF,4LWG,4LWH,4LWI,4NH7,4NH8,4O04,4O05,4O07,4O09,4O0B,4R3M,4U93,4W7T,4XIP,4XIQ,4XIR,4XIT,4YKQ,4YKR,4YKT,4YKU,4YKW,4YKX,4YKY,4YKZ,5CF0,5FNC,5FND,5FNF,5J20,5J27,5J2V,5J2X,5J64,5J82,5J86,5J9X,5LNY,5LNZ,5LO0,5LO1,5LO5,5LO6,5M4E,5M4H,5NYH,5OCI,5OD7,5ODX,5VYY,5XQD,5XQE,5XR5,5XR9,5XRB,5XRD,5XRE,5ZR3,6B99,6B9A,6CEO,6CYG,6CYH,6EI5,6EL5,6ELN,6ELO,6ELP,6EY8,6EY9,6EYA,6EYB,6F1N,6FCJ,6GPR,6GPT,6GPW,6GPY,6GQ6,6GQR,6HHR,6LR9,6LSZ,6LT8,6LTI,6LTK,6N8X,6N8Y,6U99,6U9B,7DMC,7KRJ,7KW7,7L7I,7L7J,7LSZ,7LT0,7RXZ,7RY1,7S8Y,7S8Z,7S90,7S95,7S98,7S99,7S9F,7S9G,7S9H,7S9I,7UR3,7Y04,8AGI,8H77 Heat shock protein HSP 90-alpha HS90A_HUMAN P07900 A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5