BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 77674 CCN(CC)c1ccc2c(Cl)c(Br)c(=O)oc2c1 InChI=1S/C13H13BrClNO2/c1-3-16(4-2)8-5-6-9-10(7-8)18-13(17)11(14)12(9)15/h5-7H,3-4H2,1-2H3 QYVHPITUKBNDGT-UHFFFAOYSA-N 31041 3-Bromo-4-chloro-7-diethylamino-chromen-2-one::3-bromanyl-4-chloranyl-7-(diethylamino)chromen-2-one::3-bromo-4-chloro-7-(diethylamino)-1-benzopyran-2-one::3-bromo-4-chloro-7-(diethylamino)chromen-2-one::3-bromo-4-chloro-7-(diethylamino)coumarin::MLS000029629::SMR000001240::cid_648878 Sphingosine 1-phosphate receptor 2 Homo sapiens 2530 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31041&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 648878 252615293 ZINC00362973 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77675 CCN(C(=O)c1ccc(cc1)C(C)(C)C)c1nnc(Cn2nnc3ccccc23)s1 InChI=1S/C22H24N6OS/c1-5-27(20(29)15-10-12-16(13-11-15)22(2,3)4)21-25-24-19(30-21)14-28-18-9-7-6-8-17(18)23-26-28/h6-13H,5,14H2,1-4H3 NEVNMBCJTHZTBS-UHFFFAOYSA-N 36851 MLS000072751::N-(5-Benzotriazol-1-ylmethyl-[1,3,4]thiadiazol-2-yl)-4-tert-butyl-N-ethyl-benzamide::N-[5-(1-benzotriazolylmethyl)-1,3,4-thiadiazol-2-yl]-4-tert-butyl-N-ethylbenzamide::N-[5-(benzotriazol-1-ylmethyl)-1,3,4-thiadiazol-2-yl]-4-tert-butyl-N-ethyl-benzamide::N-[5-(benzotriazol-1-ylmethyl)-1,3,4-thiadiazol-2-yl]-4-tert-butyl-N-ethylbenzamide::SMR000004710::cid_649706 Sphingosine 1-phosphate receptor 2 Homo sapiens 83760 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=36851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=36851&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 649706 252617824 ZINC01340301 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77676 CC(=O)Nc1cc(OC(C)=O)c2nonc2c1OC(C)=O InChI=1S/C12H11N3O6/c1-5(16)13-8-4-9(19-6(2)17)10-11(15-21-14-10)12(8)20-7(3)18/h4H,1-3H3,(H,13,16) AABQOSHDRSWHSN-UHFFFAOYSA-N 31042 (5-acetamido-4-acetyloxy-2,1,3-benzoxadiazol-7-yl) acetate::(5-acetamido-4-acetyloxy-2,1,3-benzoxadiazol-7-yl) ethanoate::Acetic acid 7-acetoxy-5-acetylamino-benzo[1,2,5]oxadiazol-4-yl ester::MLS000077136::SMR000008576::acetic acid (5-acetamido-4-acetyloxy-2,1,3-benzoxadiazol-7-yl) ester::acetic acid (6-acetamido-7-acetoxy-benzofurazan-4-yl) ester::cid_597363 Sphingosine 1-phosphate receptor 2 Homo sapiens 6211 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31042&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 597363 252615294 ZINC00368832 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77677 CCn1c2ccccc2c(O)c(C(=O)Nc2nc3ccccc3[nH]2)c1=O InChI=1S/C19H16N4O3/c1-2-23-14-10-6-3-7-11(14)16(24)15(18(23)26)17(25)22-19-20-12-8-4-5-9-13(12)21-19/h3-10,24H,2H2,1H3,(H2,20,21,22,25) MSIIQGRNGMMSTR-UHFFFAOYSA-N 31045 1-Ethyl-4-hydroxy-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid (1H-benzoimidazol-2-yl)-amide::MLS000027148::N-(1H-benzimidazol-2-yl)-1-ethyl-2-hydroxy-4-keto-quinoline-3-carboxamide::N-(1H-benzimidazol-2-yl)-1-ethyl-2-hydroxy-4-oxo-3-quinolinecarboxamide::N-(1H-benzimidazol-2-yl)-1-ethyl-2-hydroxy-4-oxoquinoline-3-carboxamide::N-(1H-benzimidazol-2-yl)-1-ethyl-2-oxidanyl-4-oxidanylidene-quinoline-3-carboxamide::N-(1H-benzimidazol-2-yl)-1-ethyl-4-hydroxy-2-keto-quinoline-3-carboxamide::SMR000012636::cid_654742 Sphingosine 1-phosphate receptor 2 Homo sapiens >50000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31045&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 54692915 252615297 ZINC04102870 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77678 Cc1ccc2[nH]c3c(ncnc3c2c1)N1CCCCCC1 InChI=1S/C17H20N4/c1-12-6-7-14-13(10-12)15-16(20-14)17(19-11-18-15)21-8-4-2-3-5-9-21/h6-7,10-11,20H,2-5,8-9H2,1H3 OOCYOQPXYLFKIH-UHFFFAOYSA-N 36887 4-(1-azepanyl)-8-methyl-5H-pyrimido[5,4-b]indole::4-(azepan-1-yl)-8-methyl-5H-pyrimid[5,4-b]indole::4-(azepan-1-yl)-8-methyl-5H-pyrimido[5,4-b]indole::MLS000078395::SMR000039718::cid_658731 Sphingosine 1-phosphate receptor 2 Homo sapiens 3445 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=36887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=36887&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 658731 252617860 ZINC00501513 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77679 Fc1ccc2[nH]c3c(ncnc3c2c1)N1CCN(Cc2ccc3OCOc3c2)CC1 InChI=1S/C22H20FN5O2/c23-15-2-3-17-16(10-15)20-21(26-17)22(25-12-24-20)28-7-5-27(6-8-28)11-14-1-4-18-19(9-14)30-13-29-18/h1-4,9-10,12,26H,5-8,11,13H2 HBVIUQRSDMYKQV-UHFFFAOYSA-N 36900 4-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-8-fluoro-5H-pyrimido[5,4-b]indole::4-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-8-fluoranyl-5H-pyrimido[5,4-b]indole::4-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-8-fluoro-5H-pyrimido[5,4-b]indole::8-fluoro-4-(4-piperonylpiperazino)-5H-pyrimid[5,4-b]indole::MLS000078398::SMR000040683::cid_659623 Sphingosine 1-phosphate receptor 2 Homo sapiens 3905 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=36900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=36900&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 659623 252617873 ZINC02262469 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77680 CCC(NC(=O)Nc1nnc(s1)C(F)(F)F)(C(F)(F)F)C(F)(F)F InChI=1S/C9H7F9N4OS/c1-2-6(8(13,14)15,9(16,17)18)20-4(23)19-5-22-21-3(24-5)7(10,11)12/h2H2,1H3,(H2,19,20,22,23) QFLKFRPNISNYBS-UHFFFAOYSA-N 31052 1-[1,1-bis(trifluoromethyl)propyl]-3-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]urea::1-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-3-[1,1,1-trifluoro-2-(trifluoromethyl)butan-2-yl]urea::1-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-3-[1,1,1-tris(fluoranyl)-2-(trifluoromethyl)butan-2-yl]urea::MLS000038681::SMR000040781::cid_659822 Sphingosine 1-phosphate receptor 2 Homo sapiens 4770 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31052&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 659822 252615303 ZINC02301774 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77681 CCOC(=O)c1cnc(nc1NC1CCCCC1)-n1nc(C)cc1C InChI=1S/C18H25N5O2/c1-4-25-17(24)15-11-19-18(23-13(3)10-12(2)22-23)21-16(15)20-14-8-6-5-7-9-14/h10-11,14H,4-9H2,1-3H3,(H,19,20,21) CHDHJASAMSWOTG-UHFFFAOYSA-N 36917 4-(cyclohexylamino)-2-(3,5-dimethyl-1-pyrazolyl)-5-pyrimidinecarboxylic acid ethyl ester::4-(cyclohexylamino)-2-(3,5-dimethylpyrazol-1-yl)pyrimidine-5-carboxylic acid ethyl ester::MLS000040640::SMR000042884::cid_662276::ethyl 4-(cyclohexylamino)-2-(3,5-dimethylpyrazol-1-yl)pyrimidine-5-carboxylate Sphingosine 1-phosphate receptor 2 Homo sapiens 4393 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=36917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=36917&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 662276 252617889 ZINC08762731 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77682 OC\C=C(\CS(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1 InChI=1S/C16H16O5S2/c17-12-11-16(23(20,21)15-9-5-2-6-10-15)13-22(18,19)14-7-3-1-4-8-14/h1-11,17H,12-13H2/b16-11- AIAKDUWZCKEZRU-WJDWOHSUSA-N 36923 (Z)-3,4-bis(benzenesulfonyl)-2-buten-1-ol::(Z)-3,4-bis(benzenesulfonyl)but-2-en-1-ol::(Z)-3,4-bis(phenylsulfonyl)but-2-en-1-ol::(Z)-3,4-dibesylbut-2-en-1-ol::MLS000080860::SMR000043655::cid_5389617 Sphingosine 1-phosphate receptor 2 Homo sapiens 3072 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=36923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=36923&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 5389617 252617895 ZINC04312968 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77683 COc1ccc2c(c1)[nH]c1c(ncnc21)N1CCN(Cc2ccc3OCOc3c2)CC1 InChI=1S/C23H23N5O3/c1-29-16-3-4-17-18(11-16)26-22-21(17)24-13-25-23(22)28-8-6-27(7-9-28)12-15-2-5-19-20(10-15)31-14-30-19/h2-5,10-11,13,26H,6-9,12,14H2,1H3 PJNRSCIWBIDJJA-UHFFFAOYSA-N 38908 4-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-7-methoxy-5H-pyrimido[5,4-b]indole::4-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-7-methoxy-5H-pyrimido[5,4-b]indole::7-methoxy-4-(4-piperonylpiperazino)-5H-pyrimid[5,4-b]indole::MLS000081139::SMR000043796::cid_663146 Sphingosine 1-phosphate receptor 2 Homo sapiens 4014 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38908&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 663146 252619809 ZINC02379141 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77684 COc1cccc(c1)-c1nnc2SCC(=Nn12)C(C)(C)C InChI=1S/C15H18N4OS/c1-15(2,3)12-9-21-14-17-16-13(19(14)18-12)10-6-5-7-11(8-10)20-4/h5-8H,9H2,1-4H3 WJHCCSRZEBRIMU-UHFFFAOYSA-N 39093 6-tert-butyl-3-(3-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine::MLS000081450::SMR000043797::cid_663168 Sphingosine 1-phosphate receptor 2 Homo sapiens 3308 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39093&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 663168 252619992 ZINC00531741 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77685 Cn1c(nc2ccccc12)-c1c(N)n(C2CCCC2)c2nc3ccccc3nc12 InChI=1S/C23H22N6/c1-28-18-13-7-6-12-17(18)27-22(28)19-20-23(26-16-11-5-4-10-15(16)25-20)29(21(19)24)14-8-2-3-9-14/h4-7,10-14H,2-3,8-9,24H2,1H3 NCHCGISPCBKUDS-UHFFFAOYSA-N 31060 1-cyclopentyl-3-(1-methyl-2-benzimidazolyl)-2-pyrrolo[3,2-b]quinoxalinamine::1-cyclopentyl-3-(1-methylbenzimidazol-2-yl)pyrrolo[3,2-b]quinoxalin-2-amine::MLS000083448::SMR000047968::[1-cyclopentyl-3-(1-methylbenzimidazol-2-yl)pyrrolo[3,2-b]quinoxalin-2-yl]amine::cid_666746 Sphingosine 1-phosphate receptor 2 Homo sapiens 5088 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31060&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 666746 252615311 ZINC37868707 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77686 Clc1ccc2oc(SC3=CS(=O)(=O)c4ccccc34)nc2c1 InChI=1S/C15H8ClNO3S2/c16-9-5-6-12-11(7-9)17-15(20-12)21-13-8-22(18,19)14-4-2-1-3-10(13)14/h1-8H AFYRYLBMABOAHJ-UHFFFAOYSA-N 37054 3-[(5-chloranyl-1,3-benzoxazol-2-yl)sulfanyl]-1-benzothiophene 1,1-dioxide::3-[(5-chloro-1,3-benzoxazol-2-yl)sulfanyl]-1-benzothiophene 1,1-dioxide::3-[(5-chloro-1,3-benzoxazol-2-yl)thio]-1-benzothiophene 1,1-dioxide::3-[(5-chloro-1,3-benzoxazol-2-yl)thio]benzothiophene 1,1-dioxide::5-chloro-2-[(1,1-dioxido-1-benzothien-3-yl)thio]-1,3-benzoxazole::MLS000043085::SMR000019512::cid_2928973 Sphingosine 1-phosphate receptor 2 Homo sapiens 3471 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37054&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 2928973 252618025 ZINC00089995 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77687 CCCCS(=O)(=O)\C=C/C=C\S(=O)(=O)CCCC InChI=1S/C12H22O4S2/c1-3-5-9-17(13,14)11-7-8-12-18(15,16)10-6-4-2/h7-8,11-12H,3-6,9-10H2,1-2H3/b11-7-,12-8- AWAPBXGSDGWNHK-OXAWKVHCSA-N 38993 (1Z,3Z)-1,4-bis(butylsulfonyl)buta-1,3-diene::MLS000085704::SMR000020833::cid_5286934 Sphingosine 1-phosphate receptor 2 Homo sapiens 4499 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38993&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 5286934 252619893 ZINC32219910 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77688 Fc1ccc(cc1)C(=C/c1ccc(o1)N1CCCCCC1)\C#N InChI=1S/C19H19FN2O/c20-17-7-5-15(6-8-17)16(14-21)13-18-9-10-19(23-18)22-11-3-1-2-4-12-22/h5-10,13H,1-4,11-12H2/b16-13- WHLNMNIEBYREDM-SSZFMOIBSA-N 31071 (E)-3-[5-(1-azepanyl)-2-furanyl]-2-(4-fluorophenyl)-2-propenenitrile::(E)-3-[5-(azepan-1-yl)-2-furyl]-2-(4-fluorophenyl)acrylonitrile::(E)-3-[5-(azepan-1-yl)furan-2-yl]-2-(4-fluorophenyl)prop-2-enenitrile::3-[5-(1-azepanyl)-2-furyl]-2-(4-fluorophenyl)acrylonitrile::MLS000051438::SMR000079763::cid_5740802 Sphingosine 1-phosphate receptor 2 Homo sapiens 11450 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31071&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 5740802 252615322 ZINC05051194 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77689 CCCC(=O)N1CCN(CC1)c1ccc(NC(=O)c2cc3ccccc3o2)cc1Cl InChI=1S/C23H24ClN3O3/c1-2-5-22(28)27-12-10-26(11-13-27)19-9-8-17(15-18(19)24)25-23(29)21-14-16-6-3-4-7-20(16)30-21/h3-4,6-9,14-15H,2,5,10-13H2,1H3,(H,25,29) FCYKNDPIGKYKIO-UHFFFAOYSA-N 37140 MLS000096729::N-[3-chloro-4-[4-(1-oxobutyl)-1-piperazinyl]phenyl]-2-benzofurancarboxamide::N-[4-(4-butanoylpiperazin-1-yl)-3-chloranyl-phenyl]-1-benzofuran-2-carboxamide::N-[4-(4-butanoylpiperazin-1-yl)-3-chlorophenyl]-1-benzofuran-2-carboxamide::N-[4-(4-butyryl-1-piperazinyl)-3-chlorophenyl]-1-benzofuran-2-carboxamide::N-[4-(4-butyrylpiperazino)-3-chloro-phenyl]coumarilamide::SMR000074009::cid_2944643 Sphingosine 1-phosphate receptor 2 Homo sapiens 4674 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37140&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 2944643 252618111 ZINC04058388 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77690 CCCCCCCCCn1c2CCCc2c(=N)c2CCCc12 InChI=1S/C20H32N2/c1-2-3-4-5-6-7-8-15-22-18-13-9-11-16(18)20(21)17-12-10-14-19(17)22/h21H,2-15H2,1H3 YPKABIIMSHKAFS-UHFFFAOYSA-N 41580 (4-nonyl-1,2,3,5,6,7-hexahydrodicyclopenta[1,2-c:1',2'-g]pyridin-8-ylidene)amine;hydrobromide::4-nonyl-1,2,3,5,6,7-hexahydrodicyclopenta[1,2-c:1',2'-g]pyridin-8-imine;hydrobromide::4-nonyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine::MLS000550618::SMR000114363::cid_9549110 Sphingosine 1-phosphate receptor 2 Homo sapiens 9032 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41580&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1720828 252622305 ZINC02056004 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77691 COc1ccccc1C(=O)Nc1nc(cs1)-c1ccc(cc1)S(=O)(=O)N1CCOCC1 InChI=1S/C21H21N3O5S2/c1-28-19-5-3-2-4-17(19)20(25)23-21-22-18(14-30-21)15-6-8-16(9-7-15)31(26,27)24-10-12-29-13-11-24/h2-9,14H,10-13H2,1H3,(H,22,23,25) OEWBVHQZAIHBFE-UHFFFAOYSA-N 41581 2-Methoxy-N-{4-[4-(morpholine-4-sulfonyl)-phenyl]-thiazol-2-yl}-benzamide::2-methoxy-N-[4-(4-morpholin-4-ylsulfonylphenyl)-1,3-thiazol-2-yl]benzamide::2-methoxy-N-[4-(4-morpholinosulfonylphenyl)thiazol-2-yl]benzamide::2-methoxy-N-[4-[4-(4-morpholinylsulfonyl)phenyl]-2-thiazolyl]benzamide::MLS000068567::SMR000122991::cid_979629 Sphingosine 1-phosphate receptor 2 Homo sapiens 3808 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41581&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 979629 252622306 ZINC08914346 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77692 CCOC(=O)C1C(C(C(=O)OCC)C(C)(O)CC1=O)c1ccccc1 InChI=1S/C19H24O6/c1-4-24-17(21)15-13(20)11-19(3,23)16(18(22)25-5-2)14(15)12-9-7-6-8-10-12/h6-10,14-16,23H,4-5,11H2,1-3H3 VDLSNXQRYWSHGB-UHFFFAOYSA-N 41582 4-Hydroxy-4-methyl-6-oxo-2-phenyl-cyclohexane-1,3-dicarboxylic acid diethyl ester::4-hydroxy-4-methyl-6-oxo-2-phenylcyclohexane-1,3-dicarboxylic acid diethyl ester::4-hydroxy-6-keto-4-methyl-2-phenyl-cyclohexane-1,3-dicarboxylic acid diethyl ester::MLS000120845::SMR000118258::cid_98466::diethyl 4-hydroxy-4-methyl-6-oxo-2-phenylcyclohexane-1,3-dicarboxylate::diethyl 4-methyl-4-oxidanyl-6-oxidanylidene-2-phenyl-cyclohexane-1,3-dicarboxylate Sphingosine 1-phosphate receptor 2 Homo sapiens >50000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41582&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 98466 252622307 ZINC04024292 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77693 CC1=CC(C=CC1=O)=NOS(=O)(=O)c1ccccc1 InChI=1S/C13H11NO4S/c1-10-9-11(7-8-13(10)15)14-18-19(16,17)12-5-3-2-4-6-12/h2-9H,1H3 XTGPABZHVNQSCA-UHFFFAOYSA-N 34657 MLS000121202::SMR000118624::[(3-methyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)amino] benzenesulfonate::[(3-methyl-4-oxocyclohexa-2,5-dien-1-ylidene)amino] benzenesulfonate::benzenesulfonic acid [(3-methyl-4-oxo-1-cyclohexa-2,5-dienylidene)amino] ester::benzenesulfonic acid [(4-keto-3-methyl-cyclohexa-2,5-dien-1-ylidene)amino] ester::cid_2246289 Sphingosine 1-phosphate receptor 2 Homo sapiens 5975 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34657&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 5339712 252617307 ZINC12730644 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77694 COc1ccc(OC)c(NC(=O)CSc2ncnc3n(ncc23)-c2ccccc2Cl)c1 InChI=1S/C21H18ClN5O3S/c1-29-13-7-8-18(30-2)16(9-13)26-19(28)11-31-21-14-10-25-27(20(14)23-12-24-21)17-6-4-3-5-15(17)22/h3-10,12H,11H2,1-2H3,(H,26,28) XAXFJJBRNBRHBO-UHFFFAOYSA-N 41583 2-[1-(2-Chloro-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylsulfanyl]-N-(2,5-dimethoxy-phenyl)-acetamide::2-[1-(2-chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-yl]sulfanyl-N-(2,5-dimethoxyphenyl)acetamide::2-[1-(2-chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-yl]sulfanyl-N-(2,5-dimethoxyphenyl)ethanamide::2-[[1-(2-chlorophenyl)-4-pyrazolo[3,4-d]pyrimidinyl]thio]-N-(2,5-dimethoxyphenyl)acetamide::2-[[1-(2-chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-yl]thio]-N-(2,5-dimethoxyphenyl)acetamide::MLS000121713::SMR000119135::cid_1445420 Sphingosine 1-phosphate receptor 2 Homo sapiens 3674 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41583&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1445420 252622308 ZINC01346506 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77695 Cn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccc(Cl)cc1 InChI=1S/C13H10ClN5O2/c1-18-12(20)9-11(16-13(18)21)19(2)17-10(15-9)7-3-5-8(14)6-4-7/h3-6H,1-2H3 UCEGDYDPOSBUTP-UHFFFAOYSA-N 40314 3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione::3-(4-chlorophenyl)-1,6-dimethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione::3-(4-chlorophenyl)-1,6-dimethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-quinone::3-(4-chlorophenyl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione::MLS000523518::SMR000122591::US9073941, 603::cid_460749 Sphingosine 1-phosphate receptor 2 Homo sapiens 996 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40314&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 460749 252621140 ZINC00267651 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77696 CCCCCCCCCCn1c2CCCc2c(=N)c2CCCc12 InChI=1S/C21H34N2/c1-2-3-4-5-6-7-8-9-16-23-19-14-10-12-17(19)21(22)18-13-11-15-20(18)23/h22H,2-16H2,1H3 SISXVANWPRUSHF-UHFFFAOYSA-N 41584 (4-decyl-1,2,3,5,6,7-hexahydrodicyclopenta[1,2-c:1',2'-g]pyridin-8-ylidene)amine;hydrobromide::4-Decyl-2,3,4,5,6,7-hexahydro-1H-4-aza-s-indacen-8-ylideneamine::4-decyl-1,2,3,5,6,7-hexahydrodicyclopenta[1,2-c:1',2'-g]pyridin-8-imine;hydrobromide::MLS000525289::SMR000122163::cid_9549474 Sphingosine 1-phosphate receptor 2 Homo sapiens 2943 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41584&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1568843 252622309 ZINC01778185 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77697 CC(C)(C)C(=O)C(=C/c1cccc(c1)[N+]([O-])=O)\n1cncn1 InChI=1S/C15H16N4O3/c1-15(2,3)14(20)13(18-10-16-9-17-18)8-11-5-4-6-12(7-11)19(21)22/h4-10H,1-3H3/b13-8+ VKSOIYNNOFGGES-MDWZMJQESA-N 41585 (E)-4,4-dimethyl-1-(3-nitrophenyl)-2-(1,2,4-triazol-1-yl)-1-penten-3-one::(E)-4,4-dimethyl-1-(3-nitrophenyl)-2-(1,2,4-triazol-1-yl)pent-1-en-3-one::4,4-Dimethyl-1-(3-nitro-phenyl)-2-[1,2,4]triazol-1-yl-pent-1-en-3-one::MLS000527232::SMR000117706::cid_5759185 Sphingosine 1-phosphate receptor 2 Homo sapiens 3798 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41585&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 5759185 252622310 ZINC04832804 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77698 Cc1n[nH]c(C)c1N1C(=O)c2cccc3c(Br)ccc(C1=O)c23 InChI=1S/C17H12BrN3O2/c1-8-15(9(2)20-19-8)21-16(22)11-5-3-4-10-13(18)7-6-12(14(10)11)17(21)23/h3-7H,1-2H3,(H,19,20) UKRUVKDTLCRXNL-UHFFFAOYSA-N 41586 6-Bromo-2-(3,5-dimethyl-1H-pyrazol-4-yl)-benzo[de]isoquinoline-1,3-dione::6-bromanyl-2-(3,5-dimethyl-1H-pyrazol-4-yl)benzo[de]isoquinoline-1,3-dione::6-bromo-2-(3,5-dimethyl-1H-pyrazol-4-yl)benzo[de]isoquinoline-1,3-dione::6-bromo-2-(3,5-dimethyl-1H-pyrazol-4-yl)benzo[de]isoquinoline-1,3-quinone::MLS000527154::SMR000117628::cid_1108211 Sphingosine 1-phosphate receptor 2 Homo sapiens >75530 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41586&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1108211 252622311 ZINC00840950 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77699 Cc1nn(C)c2nc(=O)n(C)c(=O)c2n1 InChI=1S/C8H9N5O2/c1-4-9-5-6(13(3)11-4)10-8(15)12(2)7(5)14/h1-3H3 CPXHNWKHOFNPDO-UHFFFAOYSA-N 34671 1,3,6-Trimethyl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione::1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione::1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-quinone::MLS000528498::SMR000121073::US9073941, 611::cid_460747 Sphingosine 1-phosphate receptor 2 Homo sapiens 1402 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34671&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 460747 252617321 ZINC00490878 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77700 COC(=O)C1CN(C#N)N(c2ccc(Cl)cc2)C11c2ccccc2-c2ccccc12 InChI=1S/C24H18ClN3O2/c1-30-23(29)22-14-27(15-26)28(17-12-10-16(25)11-13-17)24(22)20-8-4-2-6-18(20)19-7-3-5-9-21(19)24/h2-13,22H,14H2,1H3 FYASEYBMRPOWCR-UHFFFAOYSA-N 41587 2'-(4-chlorophenyl)-1'-cyano-4'-spiro[fluorene-9,3'-pyrazolidine]carboxylic acid methyl ester::2'-(4-chlorophenyl)-1'-cyano-spiro[fluorene-9,3'-pyrazolidine]-4'-carboxylic acid methyl ester::MLS000549147::SMR000113935::cid_3609942::methyl 1-(4-chlorophenyl)-2-cyanospiro[pyrazolidine-5,9'-(9'H)-fluorene]-4-carboxylate::methyl 2'-(4-chlorophenyl)-1'-cyano-spiro[fluorene-9,3'-pyrazolidine]-4'-carboxylate::methyl 2'-(4-chlorophenyl)-1'-cyanospiro[fluorene-9,3'-pyrazolidine]-4'-carboxylate Sphingosine 1-phosphate receptor 2 Homo sapiens 2789 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41587&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 3609942 252622312 ZINC00970168 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77701 O=C(Nc1cc(NC(=O)C23CC4CC(CC(C4)C2)C3)cc(c1)C(=O)N1CCCCC1)C12CC3CC(CC(C3)C1)C2 InChI=1S/C34H45N3O3/c38-30(37-4-2-1-3-5-37)27-12-28(35-31(39)33-15-21-6-22(16-33)8-23(7-21)17-33)14-29(13-27)36-32(40)34-18-24-9-25(19-34)11-26(10-24)20-34/h12-14,21-26H,1-11,15-20H2,(H,35,39)(H,36,40) CZWKWMBVBQSYHN-UHFFFAOYSA-N 41588 MLS000549502::N-[3-(1-adamantylcarbonylamino)-5-piperidin-1-ylcarbonyl-phenyl]adamantane-1-carboxamide::N-[3-(adamantane-1-carbonylamino)-5-(piperidine-1-carbonyl)phenyl]adamantane-1-carboxamide::N-[3-[(1-adamantylcarbonyl)amino]-5-(1-piperidinylcarbonyl)phenyl]-1-adamantanecarboxamide::N-[3-[[1-adamantyl(oxo)methyl]amino]-5-[oxo(1-piperidinyl)methyl]phenyl]-1-adamantanecarboxamide::SMR000114790::cid_4287683 Sphingosine 1-phosphate receptor 2 Homo sapiens 977 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41588&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 4287683 252622313 ZINC08432758 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77702 COc1ccc(NC(=O)C(\Cl)=C(\Cl)S(=O)(=O)Cc2ccc(C)cc2)cn1 InChI=1S/C17H16Cl2N2O4S/c1-11-3-5-12(6-4-11)10-26(23,24)16(19)15(18)17(22)21-13-7-8-14(25-2)20-9-13/h3-9H,10H2,1-2H3,(H,21,22)/b16-15+ WYMDXXSMQXLDSI-FOCLMDBBSA-N 41589 (Z)-2,3-bis(chloranyl)-N-(6-methoxypyridin-3-yl)-3-[(4-methylphenyl)methylsulfonyl]prop-2-enamide::(Z)-2,3-dichloro-N-(6-methoxy-3-pyridinyl)-3-[(4-methylphenyl)methylsulfonyl]-2-propenamide::(Z)-2,3-dichloro-N-(6-methoxy-3-pyridyl)-3-(4-methylbenzyl)sulfonyl-acrylamide::(Z)-2,3-dichloro-N-(6-methoxypyridin-3-yl)-3-[(4-methylphenyl)methylsulfonyl]prop-2-enamide::2,3-dichloro-N-(6-methoxy-3-pyridinyl)-3-[(4-methylbenzyl)sulfonyl]acrylamide::MLS000540306::SMR000125564::cid_1475337 Sphingosine 1-phosphate receptor 2 Homo sapiens 1484 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41589&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1475337 252622314 51689 ZINC01387414 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77703 COc1ccc(cc1)-c1c(Sc2cccc(c2)C(F)(F)F)c2ccc(OC)cc2s1=O InChI=1S/C23H17F3O3S2/c1-28-16-8-6-14(7-9-16)22-21(19-11-10-17(29-2)13-20(19)31(22)27)30-18-5-3-4-15(12-18)23(24,25)26/h3-13H,1-2H3 KDMSACVVPBXINL-UHFFFAOYSA-N 41590 6-methoxy-2-(4-methoxyphenyl)-3-[3-(trifluoromethyl)phenyl]sulfanyl-1-benzothiophene 1-oxide::6-methoxy-2-(4-methoxyphenyl)-3-[[3-(trifluoromethyl)phenyl]thio]-1-benzothiophene 1-oxide::6-methoxy-2-(4-methoxyphenyl)-3-[[3-(trifluoromethyl)phenyl]thio]benzothiophene 1-oxide::6-methoxy-2-(4-methoxyphenyl)-3-{[3-(trifluoromethyl)phenyl]sulfanyl}-1H-1-benzothiophen-1-one::MLS000540587::SMR000125845::cid_5863319 Sphingosine 1-phosphate receptor 2 Homo sapiens 7108 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41590&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 5863319 252622315 ZINC08681066 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77704 COc1ccc(NC(=O)C(Cl)=C(Cl)S(=O)Cc2ccc(C)cc2)cn1 InChI=1S/C17H16Cl2N2O3S/c1-11-3-5-12(6-4-11)10-25(23)16(19)15(18)17(22)21-13-7-8-14(24-2)20-9-13/h3-9H,10H2,1-2H3,(H,21,22) UKBGNIASULYWLD-UHFFFAOYSA-N 41591 (Z)-2,3-bis(chloranyl)-N-(6-methoxypyridin-3-yl)-3-[(4-methylphenyl)methylsulfinyl]prop-2-enamide::(Z)-2,3-dichloro-N-(6-methoxy-3-pyridinyl)-3-[(4-methylphenyl)methylsulfinyl]-2-propenamide::(Z)-2,3-dichloro-N-(6-methoxy-3-pyridyl)-3-(4-methylbenzyl)sulfinyl-acrylamide::(Z)-2,3-dichloro-N-(6-methoxypyridin-3-yl)-3-[(4-methylphenyl)methylsulfinyl]prop-2-enamide::2,3-dichloro-N-(6-methoxy-3-pyridinyl)-3-[(4-methylbenzyl)sulfinyl]acrylamide::MLS000540304::SMR000125562::cid_1472225 Sphingosine 1-phosphate receptor 2 Homo sapiens 967 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41591&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1472225 252622316 51689 ZINC12954776 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77705 COc1ccc(NC(=O)C(\Cl)=C(\Cl)S(=O)(=O)Cc2ccccc2)cn1 InChI=1S/C16H14Cl2N2O4S/c1-24-13-8-7-12(9-19-13)20-16(21)14(17)15(18)25(22,23)10-11-5-3-2-4-6-11/h2-9H,10H2,1H3,(H,20,21)/b15-14+ RSCMVRBCGVUKGX-CCEZHUSRSA-N 41592 (Z)-2,3-bis(chloranyl)-N-(6-methoxypyridin-3-yl)-3-(phenylmethyl)sulfonyl-prop-2-enamide::(Z)-2,3-dichloro-N-(6-methoxy-3-pyridinyl)-3-(phenylmethyl)sulfonyl-2-propenamide::(Z)-3-benzylsulfonyl-2,3-dichloro-N-(6-methoxy-3-pyridyl)acrylamide::(Z)-3-benzylsulfonyl-2,3-dichloro-N-(6-methoxypyridin-3-yl)prop-2-enamide::3-(benzylsulfonyl)-2,3-dichloro-N-(6-methoxy-3-pyridinyl)acrylamide::MLS000540303::SMR000125561::cid_1472218 Sphingosine 1-phosphate receptor 2 Homo sapiens 1759 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41592&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1472218 252622317 51689 ZINC01383601 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77706 COc1ccc(NC(=O)C(Cl)=C(Cl)S(=O)Cc2ccccc2)cn1 InChI=1S/C16H14Cl2N2O3S/c1-23-13-8-7-12(9-19-13)20-16(21)14(17)15(18)24(22)10-11-5-3-2-4-6-11/h2-9H,10H2,1H3,(H,20,21) XNTUIWIKFGPDFS-UHFFFAOYSA-N 41593 (Z)-2,3-bis(chloranyl)-N-(6-methoxypyridin-3-yl)-3-(phenylmethyl)sulfinyl-prop-2-enamide::(Z)-2,3-dichloro-N-(6-methoxy-3-pyridinyl)-3-(phenylmethyl)sulfinyl-2-propenamide::(Z)-3-benzylsulfinyl-2,3-dichloro-N-(6-methoxy-3-pyridyl)acrylamide::(Z)-3-benzylsulfinyl-2,3-dichloro-N-(6-methoxypyridin-3-yl)prop-2-enamide::3-(benzylsulfinyl)-2,3-dichloro-N-(6-methoxy-3-pyridinyl)acrylamide::MLS000540302::SMR000125560::cid_1472216 Sphingosine 1-phosphate receptor 2 Homo sapiens 942 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41593&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1472216 252622318 51689 ZINC12952756 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77707 COc1ccc(CS(=O)(=O)C(\Cl)=C(\Cl)C(=O)Nc2ccc(OC)nc2)cc1 InChI=1S/C17H16Cl2N2O5S/c1-25-13-6-3-11(4-7-13)10-27(23,24)16(19)15(18)17(22)21-12-5-8-14(26-2)20-9-12/h3-9H,10H2,1-2H3,(H,21,22)/b16-15+ ZXUIHBQNPSDKNZ-FOCLMDBBSA-N 41594 (Z)-2,3-bis(chloranyl)-3-[(4-methoxyphenyl)methylsulfonyl]-N-(6-methoxypyridin-3-yl)prop-2-enamide::(Z)-2,3-dichloro-3-[(4-methoxyphenyl)methylsulfonyl]-N-(6-methoxy-3-pyridinyl)-2-propenamide::(Z)-2,3-dichloro-3-[(4-methoxyphenyl)methylsulfonyl]-N-(6-methoxypyridin-3-yl)prop-2-enamide::(Z)-2,3-dichloro-N-(6-methoxy-3-pyridyl)-3-p-anisylsulfonyl-acrylamide::2,3-dichloro-3-[(4-methoxybenzyl)sulfonyl]-N-(6-methoxy-3-pyridinyl)acrylamide::MLS000540307::SMR000125565::cid_1475343 Sphingosine 1-phosphate receptor 2 Homo sapiens 1675 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41594&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1475343 252622319 51689 ZINC06181882 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77708 Fc1ccc(NC(=O)c2sc3cc(cnc3c2-c2cccs2)C(F)(F)F)cc1 InChI=1S/C19H10F4N2OS2/c20-11-3-5-12(6-4-11)25-18(26)17-15(13-2-1-7-27-13)16-14(28-17)8-10(9-24-16)19(21,22)23/h1-9H,(H,25,26) OILXMQDCLHYXBN-UHFFFAOYSA-N 41595 MLS000540468::N-(4-fluorophenyl)-3-(2-thienyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide::N-(4-fluorophenyl)-3-thiophen-2-yl-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxamide::N-(4-fluorophenyl)-3-thiophen-2-yl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide::SMR000125726::cid_2765371 Sphingosine 1-phosphate receptor 2 Homo sapiens 2730 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41595&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 2765371 252622320 ZINC08671981 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77709 FC(F)(F)c1cc(c2ccc(nc2n1)C(C#N)c1cccc(Cl)c1)C(F)(F)F InChI=1S/C18H8ClF6N3/c19-10-3-1-2-9(6-10)12(8-26)14-5-4-11-13(17(20,21)22)7-15(18(23,24)25)28-16(11)27-14/h1-7,12H QPWWAOMXYPIDOY-UHFFFAOYSA-N 41596 2-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-(3-chlorophenyl)acetonitrile::2-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-(3-chlorophenyl)ethanenitrile::2-[5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-yl]-2-(3-chlorophenyl)acetonitrile::MLS000540886::SMR000125944::cid_3803930 Sphingosine 1-phosphate receptor 2 Homo sapiens 922 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41596&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 3803930 252622321 ZINC08665033 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77710 CC1=C(C)C(C=CC1=O)=NOS(=O)(=O)c1ccccc1 InChI=1S/C14H13NO4S/c1-10-11(2)14(16)9-8-13(10)15-19-20(17,18)12-6-4-3-5-7-12/h3-9H,1-2H3 HBNYMWXXUGEESV-UHFFFAOYSA-N 41597 2,3-dimethyl-4-{[(phenylsulfonyl)oxy]imino}-2,5-cyclohexadien-1-one::MLS000535052::SMR000142489::[(2,3-dimethyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)amino] benzenesulfonate::[(2,3-dimethyl-4-oxocyclohexa-2,5-dien-1-ylidene)amino] benzenesulfonate::benzenesulfonic acid [(2,3-dimethyl-4-oxo-1-cyclohexa-2,5-dienylidene)amino] ester::benzenesulfonic acid [(4-keto-2,3-dimethyl-cyclohexa-2,5-dien-1-ylidene)amino] ester::cid_1587413 Sphingosine 1-phosphate receptor 2 Homo sapiens 4326 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41597&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 5736620 252622322 ZINC13468720 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77711 CCN1\C(=C\c2ccc3ccccc3[n+]2CC)C=Cc2ccccc12 InChI=1S/C23H23N2/c1-3-24-20(15-13-18-9-5-7-11-22(18)24)17-21-16-14-19-10-6-8-12-23(19)25(21)4-2/h5-17H,3-4H2,1-2H3/q+1 AGJZCWVTGOVGBS-UHFFFAOYSA-N 39687 (2E)-1-ethyl-2-[(1-ethyl-2-quinolin-1-iumyl)methylidene]quinoline;chloride::(2E)-1-ethyl-2-[(1-ethylquinolin-1-ium-2-yl)methylene]quinoline;chloride::(2E)-1-ethyl-2-[(1-ethylquinolin-1-ium-2-yl)methylidene]quinoline;chloride::1-ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]quinolinium chloride::CHEMBL1197556::MLS000532635::SMR000137574::cid_5717105 Sphingosine 1-phosphate receptor 2 Homo sapiens 3104 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39687&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 5484463 252620573 38004 CHEMBL1197556 ZINC03877501 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77712 CCCCCCCCNc1ncnc2ccccc12 InChI=1S/C16H23N3/c1-2-3-4-5-6-9-12-17-16-14-10-7-8-11-15(14)18-13-19-16/h7-8,10-11,13H,2-6,9,12H2,1H3,(H,17,18,19) SUSULHXCDDVZDI-UHFFFAOYSA-N 39698 MLS000519095::N-octyl-4-quinazolinamine::N-octylquinazolin-4-amine::SMR000129514::cid_9550933::octyl(quinazolin-4-yl)amine Sphingosine 1-phosphate receptor 2 Homo sapiens 1230 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39698&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 9550933 252620584 ZINC08801913 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77713 CCOC(=O)N1CCN(CC1)C(=O)CSCC(=O)Nc1nc(cs1)-c1ccc(cc1)-c1ccccc1 InChI=1S/C26H28N4O4S2/c1-2-34-26(33)30-14-12-29(13-15-30)24(32)18-35-17-23(31)28-25-27-22(16-36-25)21-10-8-20(9-11-21)19-6-4-3-5-7-19/h3-11,16H,2,12-15,17-18H2,1H3,(H,27,28,31) APVKJTYNBUKNKK-UHFFFAOYSA-N 41598 4-[1-oxo-2-[[2-oxo-2-[[4-(4-phenylphenyl)-2-thiazolyl]amino]ethyl]thio]ethyl]-1-piperazinecarboxylic acid ethyl ester::4-[2-[[2-keto-2-[[4-(4-phenylphenyl)thiazol-2-yl]amino]ethyl]thio]acetyl]piperazine-1-carboxylic acid ethyl ester::MLS000529745::SMR000126825::cid_5235407::ethyl 4-[2-[2-oxidanylidene-2-[[4-(4-phenylphenyl)-1,3-thiazol-2-yl]amino]ethyl]sulfanylethanoyl]piperazine-1-carboxylate::ethyl 4-[2-[2-oxo-2-[[4-(4-phenylphenyl)-1,3-thiazol-2-yl]amino]ethyl]sulfanylacetyl]piperazine-1-carboxylate Sphingosine 1-phosphate receptor 2 Homo sapiens 2467 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41598&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 5235407 252622323 ZINC08653919 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77714 Cc1cc(C=Nn2cnnc2)c(C)n1-c1ccc(OCc2ccc(Cl)cc2)cc1 InChI=1S/C22H20ClN5O/c1-16-11-19(12-26-27-14-24-25-15-27)17(2)28(16)21-7-9-22(10-8-21)29-13-18-3-5-20(23)6-4-18/h3-12,14-15H,13H2,1-2H3 JAMPQIXPGFUGOH-UHFFFAOYSA-N 41599 (E)-[1-[4-(4-chlorobenzyl)oxyphenyl]-2,5-dimethyl-pyrrol-3-yl]methylene-(1,2,4-triazol-4-yl)amine::1-[1-[4-[(4-chlorophenyl)methoxy]phenyl]-2,5-dimethyl-3-pyrrolyl]-N-(1,2,4-triazol-4-yl)methanimine::1-[1-[4-[(4-chlorophenyl)methoxy]phenyl]-2,5-dimethyl-pyrrol-3-yl]-N-(1,2,4-triazol-4-yl)methanimine::1-[1-[4-[(4-chlorophenyl)methoxy]phenyl]-2,5-dimethylpyrrol-3-yl]-N-(1,2,4-triazol-4-yl)methanimine::MLS000534371::N-[(1-{4-[(4-chlorobenzyl)oxy]phenyl}-2,5-dimethyl-1H-pyrrol-3-yl)methylene]-4H-1,2,4-triazol-4-amine::SMR000141803::[1-[4-(4-chlorobenzyl)oxyphenyl]-2,5-dimethyl-pyrrol-3-yl]methylene-(1,2,4-triazol-4-yl)amine::cid_1282232 Sphingosine 1-phosphate receptor 2 Homo sapiens 49350 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41599&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 6859942 252622324 ZINC01101517 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77715 [O-][N+](=O)c1cccc(c1)C#CC(=O)c1ccccc1 InChI=1S/C15H9NO3/c17-15(13-6-2-1-3-7-13)10-9-12-5-4-8-14(11-12)16(18)19/h1-8,11H PPFBVVKWYQVYKJ-UHFFFAOYSA-N 41600 3-(3-nitrophenyl)-1-phenyl-2-propyn-1-one::3-(3-nitrophenyl)-1-phenyl-prop-2-yn-1-one::3-(3-nitrophenyl)-1-phenylprop-2-yn-1-one::MLS000532224::SMR000137164::cid_1211724 Sphingosine 1-phosphate receptor 2 Homo sapiens 3688 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41600&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1211724 252622325 51723 ZINC00984397 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77716 Cc1nn(c2N=C3N(C(c12)c1ccc(O)c(O)c1)c1ccccc1N=C3Nc1cccc(C)c1)-c1ccccc1 InChI=1S/C32H26N6O2/c1-19-9-8-10-22(17-19)33-30-32-35-31-28(20(2)36-38(31)23-11-4-3-5-12-23)29(21-15-16-26(39)27(40)18-21)37(32)25-14-7-6-13-24(25)34-30/h3-18,29,39-40H,1-2H3,(H,33,34) VDXQGNUWBUFDMK-UHFFFAOYSA-N 41601 4-(10-Methyl-8-phenyl-6-m-tolylamino-8,11-dihydro-5,7,8,9,11a-pentaaza-cyclopenta[b]phenanthren-11 -yl)-benzene-1,2-diol::MLS000551459::SMR000145384::cid_3449225 Sphingosine 1-phosphate receptor 2 Homo sapiens 4374 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41601&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 3449225 242053004 ZINC02220737 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77717 Cc1ccc2[nH]c3c(ncnc3c2c1)N1CCc2ccccc2C1 InChI=1S/C20H18N4/c1-13-6-7-17-16(10-13)18-19(23-17)20(22-12-21-18)24-9-8-14-4-2-3-5-15(14)11-24/h2-7,10,12,23H,8-9,11H2,1H3 XYPQUWRVEBRFOQ-UHFFFAOYSA-N 41602 4-(3,4-dihydro-1H-isoquinolin-2-yl)-8-methyl-5H-pyrimid[5,4-b]indole::4-(3,4-dihydro-1H-isoquinolin-2-yl)-8-methyl-5H-pyrimido[5,4-b]indole::MLS000555908::SMR000147425::cid_917237 Sphingosine 1-phosphate receptor 2 Homo sapiens 3627 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41602&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 917237 252622326 ZINC00503740 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77718 Cc1nn(c2N=C3N(C(c12)c1ccc(O)c(O)c1)c1ccccc1N=C3Nc1ccc(C)cc1)-c1ccccc1 InChI=1S/C32H26N6O2/c1-19-12-15-22(16-13-19)33-30-32-35-31-28(20(2)36-38(31)23-8-4-3-5-9-23)29(21-14-17-26(39)27(40)18-21)37(32)25-11-7-6-10-24(25)34-30/h3-18,29,39-40H,1-2H3,(H,33,34) OBDULIDEUMLMLL-UHFFFAOYSA-N 41603 4-(10-Methyl-8-phenyl-6-p-tolylamino-8,11-dihydro-5,7,8,9,11a-pentaaza-cyclopenta[b]phenanthren-11 -yl)-benzene-1,2-diol::MLS000551449::SMR000145374::cid_4269692 Sphingosine 1-phosphate receptor 2 Homo sapiens 4503 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41603&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 4269692 242053005 ZINC02368886 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77719 Cc1nn(c2N=C3N(C(c12)c1ccc(O)c(O)c1)c1ccccc1N=C3Nc1ccccc1)-c1ccccc1 InChI=1S/C31H24N6O2/c1-19-27-28(20-16-17-25(38)26(39)18-20)36-24-15-9-8-14-23(24)33-29(32-21-10-4-2-5-11-21)31(36)34-30(27)37(35-19)22-12-6-3-7-13-22/h2-18,28,38-39H,1H3,(H,32,33) NWCSVPLYCSMGDA-UHFFFAOYSA-N 41604 4-(10-Methyl-8-phenyl-6-phenylamino-8,11-dihydro-5,7,8,9,11a-pentaaza-cyclopenta[b]phenanthren-11 -yl)-benzene-1,2-diol::MLS000551460::SMR000145385::cid_4325987 Sphingosine 1-phosphate receptor 2 Homo sapiens 4684 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41604&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 4325987 242053006 ZINC02212558 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77720 Cn1c(nc2ccccc12)-c1c(N)n(CCCc2ccccc2)c2nc3ccccc3nc12 InChI=1S/C27H24N6/c1-32-22-16-8-7-15-21(22)31-26(32)23-24-27(30-20-14-6-5-13-19(20)29-24)33(25(23)28)17-9-12-18-10-3-2-4-11-18/h2-8,10-11,13-16H,9,12,17,28H2,1H3 BQQWMXUYUQDOGR-UHFFFAOYSA-N 41605 3-(1-Methyl-1H-benzoimidazol-2-yl)-1-(3-phenyl-propyl)-1H-pyrrolo[2,3-b]quinoxalin-2-ylamine::3-(1-methyl-2-benzimidazolyl)-1-(3-phenylpropyl)-2-pyrrolo[3,2-b]quinoxalinamine::3-(1-methylbenzimidazol-2-yl)-1-(3-phenylpropyl)pyrrolo[3,2-b]quinoxalin-2-amine::MLS000559002::SMR000149318::[3-(1-methylbenzimidazol-2-yl)-1-(3-phenylpropyl)pyrrolo[3,2-b]quinoxalin-2-yl]amine::cid_4971561 Sphingosine 1-phosphate receptor 2 Homo sapiens 8004 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41605&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 4971561 252622327 ZINC08666037 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77721 CCN1\C(=C/C=C/C2=[N+](CC)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 InChI=1S/C27H33N2/c1-7-28-22-16-11-9-14-20(22)26(3,4)24(28)18-13-19-25-27(5,6)21-15-10-12-17-23(21)29(25)8-2/h9-19H,7-8H2,1-6H3/q+1 PUIDNHIQNRMZGS-UHFFFAOYSA-N 39718 (2Z)-1-ethyl-2-[(E)-3-(1-ethyl-3,3-dimethyl-2-indol-1-iumyl)prop-2-enylidene]-3,3-dimethylindole;perchlorate::(2Z)-1-ethyl-2-[(E)-3-(1-ethyl-3,3-dimethyl-indol-1-ium-2-yl)prop-2-enylidene]-3,3-dimethyl-indole;perchlorate::(2Z)-1-ethyl-2-[(E)-3-(1-ethyl-3,3-dimethylindol-1-ium-2-yl)prop-2-enylidene]-3,3-dimethylindole;perchlorate::1-ethyl-2-[(E,3E)-3-(1-ethyl-3,3-dimethyl-indolin-2-ylidene)prop-1-enyl]-3,3-dimethyl-indol-1-ium;perchlorate::1-ethyl-2-[(E,3Z)-3-(1-ethyl-3,3-dimethyl-indolin-2-ylidene)prop-1-enyl]-3,3-dimethyl-indol-1-ium;perchlorate::MLS000536778::SMR000155663::cid_9551964 Sphingosine 1-phosphate receptor 2 Homo sapiens 587 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39718&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 6914143 252620604 ZINC04521388 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77722 Cc1ccc(cc1)-n1c(c[n+]-2c1CCc1ccc3cccnc3c-21)-c1ccc(Br)cc1 InChI=1S/C27H21BrN3/c1-18-4-13-23(14-5-18)31-24(19-8-11-22(28)12-9-19)17-30-25(31)15-10-21-7-6-20-3-2-16-29-26(20)27(21)30/h2-9,11-14,16-17H,10,15H2,1H3/q+1 XZGBHFABTFSDLU-UHFFFAOYSA-N 40695 10-(4-bromophenyl)-9-(4-methylphenyl)-7,8-dihydroimidazo[1,2-a][1,10]phenanthrolin-12-ium;bromide::10-(4-bromophenyl)-9-(p-tolyl)-7,8-dihydroimidazo[1,2-a][1,10]phenanthrolin-12-ium;bromide::MLS000565339::SMR000152588::cid_9551998 Sphingosine 1-phosphate receptor 2 Homo sapiens 4278 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40695&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 2319091 252621513 ZINC13110677 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77723 Oc1cc(=C)c(NOS(=O)(=O)c2ccccc2)cc1=C InChI=1S/C14H13NO4S/c1-10-9-14(16)11(2)8-13(10)15-19-20(17,18)12-6-4-3-5-7-12/h3-9,15-16H,1-2H2 JNZLKQWCDQPZFY-UHFFFAOYSA-N 34707 MLS000571067::SMR000150695::[(2,5-dimethyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)amino] benzenesulfonate::[(2,5-dimethyl-4-oxocyclohexa-2,5-dien-1-ylidene)amino] benzenesulfonate::benzenesulfonic acid [(2,5-dimethyl-4-oxo-1-cyclohexa-2,5-dienylidene)amino] ester::benzenesulfonic acid [(4-keto-2,5-dimethyl-cyclohexa-2,5-dien-1-ylidene)amino] ester::cid_2303313 Sphingosine 1-phosphate receptor 2 Homo sapiens 3710 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34707&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 91896214 252617356 ZINC12658763 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77724 [O-][N+](=O)c1ccc2nc(NC(NC(=O)c3ccccc3)(C(F)(F)F)C(F)(F)F)sc2c1 InChI=1S/C17H10F6N4O3S/c18-16(19,20)15(17(21,22)23,25-13(28)9-4-2-1-3-5-9)26-14-24-11-7-6-10(27(29)30)8-12(11)31-14/h1-8H,(H,24,26)(H,25,28) RVALRXZLYFQZGR-UHFFFAOYSA-N 41606 MLS000324745::N-[1,1,1,3,3,3-hexafluoro-2-[(6-nitro-1,3-benzothiazol-2-yl)amino]propan-2-yl]benzamide::N-[1,1,1,3,3,3-hexakis(fluoranyl)-2-[(6-nitro-1,3-benzothiazol-2-yl)amino]propan-2-yl]benzamide::N-[2,2,2-trifluoro-1-({6-nitro-1,3-benzothiazol-2-yl}amino)-1-(trifluoromethyl)ethyl]benzamide::N-[2,2,2-trifluoro-1-[(6-nitro-1,3-benzothiazol-2-yl)amino]-1-(trifluoromethyl)ethyl]benzamide::SMR000163420::cid_570353 Sphingosine 1-phosphate receptor 2 Homo sapiens 682 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41606&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 570353 252622328 ZINC02050344 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77725 Clc1ccccc1C(=O)OCn1ncc(Cl)c(Cl)c1=O InChI=1S/C12H7Cl3N2O3/c13-8-4-2-1-3-7(8)12(19)20-6-17-11(18)10(15)9(14)5-16-17/h1-5H,6H2 XUUFIOHTEHAJQL-UHFFFAOYSA-N 41607 (4,5-dichloro-6-oxopyridazin-1-yl)methyl 2-chlorobenzoate::2-chlorobenzoic acid (4,5-dichloro-6-keto-pyridazin-1-yl)methyl ester::2-chlorobenzoic acid (4,5-dichloro-6-oxo-1-pyridazinyl)methyl ester::MLS000546962::SMR000180160::[4,5-bis(chloranyl)-6-oxidanylidene-pyridazin-1-yl]methyl 2-chloranylbenzoate::[4,5-dichloro-6-oxo-1(6H)-pyridazinyl]methyl 2-chlorobenzenecarboxylate::cid_1474461 Sphingosine 1-phosphate receptor 2 Homo sapiens 3153 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41607 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41607&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1474461 252622329 ZINC01386230 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77726 Fc1ccc(cc1)C(=O)OCn1ncc(Cl)c(Cl)c1=O InChI=1S/C12H7Cl2FN2O3/c13-9-5-16-17(11(18)10(9)14)6-20-12(19)7-1-3-8(15)4-2-7/h1-5H,6H2 YIGYFDAHCNYMIX-UHFFFAOYSA-N 41608 (4,5-dichloro-6-oxopyridazin-1-yl)methyl 4-fluorobenzoate::4-fluorobenzoic acid (4,5-dichloro-6-keto-pyridazin-1-yl)methyl ester::4-fluorobenzoic acid (4,5-dichloro-6-oxo-1-pyridazinyl)methyl ester::MLS000546963::SMR000180161::[4,5-bis(chloranyl)-6-oxidanylidene-pyridazin-1-yl]methyl 4-fluoranylbenzoate::[4,5-dichloro-6-oxo-1(6H)-pyridazinyl]methyl 4-fluorobenzenecarboxylate::cid_1474462 Sphingosine 1-phosphate receptor 2 Homo sapiens 3765 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41608&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1474462 252622330 ZINC01386231 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77727 Cc1ccc(cc1)C(=O)OCn1ncc(Cl)c(Cl)c1=O InChI=1S/C13H10Cl2N2O3/c1-8-2-4-9(5-3-8)13(19)20-7-17-12(18)11(15)10(14)6-16-17/h2-6H,7H2,1H3 FLFFUOCCWRXKSU-UHFFFAOYSA-N 41609 (4,5-dichloro-6-oxopyridazin-1-yl)methyl 4-methylbenzoate::4-methylbenzoic acid (4,5-dichloro-6-keto-pyridazin-1-yl)methyl ester::4-methylbenzoic acid (4,5-dichloro-6-oxo-1-pyridazinyl)methyl ester::MLS000546966::SMR000180164::[4,5-bis(chloranyl)-6-oxidanylidene-pyridazin-1-yl]methyl 4-methylbenzoate::[4,5-dichloro-6-oxo-1(6H)-pyridazinyl]methyl 4-methylbenzenecarboxylate::cid_1474465 Sphingosine 1-phosphate receptor 2 Homo sapiens 2652 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41609&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1474465 252622331 ZINC01386234 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77728 Fc1ccc(cc1)-n1nnnc1-c1cnc(nc1C(F)(F)F)-c1cccs1 InChI=1S/C16H8F4N6S/c17-9-3-5-10(6-4-9)26-15(23-24-25-26)11-8-21-14(12-2-1-7-27-12)22-13(11)16(18,19)20/h1-8H MVHXEQFYJFVGQN-UHFFFAOYSA-N 41610 5-[1-(4-fluorophenyl)-1,2,3,4-tetrazol-5-yl]-2-thiophen-2-yl-4-(trifluoromethyl)pyrimidine::5-[1-(4-fluorophenyl)-1H-tetraazol-5-yl]-2-(2-thienyl)-4-(trifluoromethyl)pyrimidine::5-[1-(4-fluorophenyl)-5-tetrazolyl]-2-thiophen-2-yl-4-(trifluoromethyl)pyrimidine::5-[1-(4-fluorophenyl)tetrazol-5-yl]-2-(2-thienyl)-4-(trifluoromethyl)pyrimidine::5-[1-(4-fluorophenyl)tetrazol-5-yl]-2-thiophen-2-yl-4-(trifluoromethyl)pyrimidine::MLS000546030::SMR000163469::cid_4112227 Sphingosine 1-phosphate receptor 2 Homo sapiens 5199 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41610&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 4112227 252622332 ZINC04568133 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77729 CCN1\C(Sc2ccccc12)=C\c1ccc2cccc(C)c2[n+]1CC InChI=1S/C22H23N2S/c1-4-23-18(14-13-17-10-8-9-16(3)22(17)23)15-21-24(5-2)19-11-6-7-12-20(19)25-21/h6-15H,4-5H2,1-3H3/q+1 WNDBSXDDIYRNJG-UHFFFAOYSA-N 39773 (2Z)-3-ethyl-2-[(1-ethyl-8-methyl-2-quinolin-1-iumyl)methylidene]-1,3-benzothiazole;iodide::(2Z)-3-ethyl-2-[(1-ethyl-8-methyl-quinolin-1-ium-2-yl)methylene]-1,3-benzothiazole;iodide::(2Z)-3-ethyl-2-[(1-ethyl-8-methyl-quinolin-1-ium-2-yl)methylidene]-1,3-benzothiazole;iodide::(2Z)-3-ethyl-2-[(1-ethyl-8-methylquinolin-1-ium-2-yl)methylidene]-1,3-benzothiazole;iodide::1-Ethyl-2-(3-ethyl-3H-benzothiazol-2-ylidenemethyl)-8-methyl-quinolinium::MLS000556089::SMR000177972::cid_11958727 Sphingosine 1-phosphate receptor 2 Homo sapiens 2939 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39773&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 5767645 252620659 ZINC33933311 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77730 Nc1nc(Cl)cc(n1)N1CCC(CC1)c1cc(n[nH]1)-c1ccc(Cl)cc1 InChI=1S/C18H18Cl2N6/c19-13-3-1-11(2-4-13)14-9-15(25-24-14)12-5-7-26(8-6-12)17-10-16(20)22-18(21)23-17/h1-4,9-10,12H,5-8H2,(H,24,25)(H2,21,22,23) INVJQALBOFMPJQ-UHFFFAOYSA-N 41611 4-chloranyl-6-[4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-1-yl]pyrimidin-2-amine::4-chloro-6-[4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-1-piperidinyl]-2-pyrimidinamine::4-chloro-6-[4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-1-yl]pyrimidin-2-amine::4-chloro-6-{4-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]piperidino}-2-pyrimidinamine::MLS000327676::SMR000180723::[4-chloro-6-[4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidino]pyrimidin-2-yl]amine::cid_11958855 Sphingosine 1-phosphate receptor 2 Homo sapiens 7011 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41611&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 11958855 252622333 ZINC15974430 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77731 O=C(Nc1ccc(cc1)S(=O)(=O)N1CCOCC1)c1ccc(CN2CCc3ccccc3C2)cc1 InChI=1S/C27H29N3O4S/c31-27(28-25-9-11-26(12-10-25)35(32,33)30-15-17-34-18-16-30)23-7-5-21(6-8-23)19-29-14-13-22-3-1-2-4-24(22)20-29/h1-12H,13-20H2,(H,28,31) WGQPJPGVHXXIAT-UHFFFAOYSA-N 41612 4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-morpholin-4-ylsulfonylphenyl)benzamide::4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-morpholinosulfonylphenyl)benzamide::4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide::4-(3,4-dihydro-2(1H)-isoquinolinylmethyl)-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide::MLS000580544::SMR000199432::cid_1288978 Sphingosine 1-phosphate receptor 2 Homo sapiens 3769 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41612&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1288978 252622334 ZINC19921226 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77732 Cc1ccc(cc1)-c1nn(cc1C=NNC(=O)c1ccc(Br)o1)-c1ccccc1 InChI=1S/C22H17BrN4O2/c1-15-7-9-16(10-8-15)21-17(14-27(26-21)18-5-3-2-4-6-18)13-24-25-22(28)19-11-12-20(23)29-19/h2-14H,1H3,(H,25,28) LZSQIAUJZAMIJA-UHFFFAOYSA-N 41613 5-bromanyl-N-[[3-(4-methylphenyl)-1-phenyl-pyrazol-4-yl]methylideneamino]furan-2-carboxamide::5-bromo-N'-{[3-(4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-2-furohydrazide::5-bromo-N-[[1-phenyl-3-(p-tolyl)pyrazol-4-yl]methyleneamino]-2-furamide::5-bromo-N-[[3-(4-methylphenyl)-1-phenyl-4-pyrazolyl]methylideneamino]-2-furancarboxamide::5-bromo-N-[[3-(4-methylphenyl)-1-phenylpyrazol-4-yl]methylideneamino]furan-2-carboxamide::MLS000570981::SMR000187045::cid_1365339 Sphingosine 1-phosphate receptor 2 Homo sapiens 3357 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41613&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 6897238 252622335 ZINC15987870 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77733 Cn1c2NC(=NC(c2c(=O)n(C)c1=O)(C(F)(F)F)C(F)(F)F)c1ccc(Cl)cc1 InChI=1S/C16H11ClF6N4O2/c1-26-11-9(12(28)27(2)13(26)29)14(15(18,19)20,16(21,22)23)25-10(24-11)7-3-5-8(17)6-4-7/h3-6H,1-2H3,(H,24,25) MFEIZMHODFOWAT-UHFFFAOYSA-N 41614 7-(4-chlorophenyl)-1,3-dimethyl-5,5-bis(trifluoromethyl)-5,8-dihydropyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione::7-(4-chlorophenyl)-1,3-dimethyl-5,5-bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidine-2,4-dione::7-(4-chlorophenyl)-1,3-dimethyl-5,5-bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidine-2,4-quinone::MLS000581848::SMR000200452::cid_1941609 Sphingosine 1-phosphate receptor 2 Homo sapiens 3792 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41614&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1941609 252622336 ZINC02326817 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77734 NC(=O)c1sc2cc(cnc2c1-c1cccs1)C(F)(F)F InChI=1S/C13H7F3N2OS2/c14-13(15,16)6-4-8-10(18-5-6)9(7-2-1-3-20-7)11(21-8)12(17)19/h1-5H,(H2,17,19) ZUFCVIFIFYOWBE-UHFFFAOYSA-N 41615 3-(2-thienyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide::3-thiophen-2-yl-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxamide::3-thiophen-2-yl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide::SR-01000666476-2::cid_1486484 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41615&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1486484 252622337 ZINC01400638 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77735 OC(=O)c1sc2cc(cnc2c1-c1cccs1)C(F)(F)F InChI=1S/C13H6F3NO2S2/c14-13(15,16)6-4-8-10(17-5-6)9(7-2-1-3-20-7)11(21-8)12(18)19/h1-5H,(H,18,19) DATGNBAKWXHSMN-UHFFFAOYSA-N 41616 3-(2-thienyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid::3-thiophen-2-yl-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxylic acid::3-thiophen-2-yl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid::SR-01000742639-2::cid_1486483 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41616&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1486483 252622338 ZINC01400637 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77736 CN(C)\C=N\C(=O)c1sc2cc(cnc2c1-c1cccs1)C(F)(F)F InChI=1S/C16H12F3N3OS2/c1-22(2)8-21-15(23)14-12(10-4-3-5-24-10)13-11(25-14)6-9(7-20-13)16(17,18)19/h3-8H,1-2H3/b21-8+ XLRQAVRXBRIRBU-ODCIPOBUSA-N 41617 N-(dimethylaminomethylene)-3-(2-thienyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide::N-(dimethylaminomethylidene)-3-thiophen-2-yl-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxamide::N-(dimethylaminomethylidene)-3-thiophen-2-yl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide::SR-01000759125-1::cid_2765372 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41617&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 2765372 252622339 ZINC04002204 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77737 FC(F)(F)c1cnc2c(-c3cccs3)c(sc2c1)-c1nnc[nH]1 InChI=1S/C14H7F3N4S2/c15-14(16,17)7-4-9-11(18-5-7)10(8-2-1-3-22-8)12(23-9)13-19-6-20-21-13/h1-6H,(H,19,20,21) QASVFDRZPXOVAN-UHFFFAOYSA-N 41618 3-(2-thienyl)-2-(1H-1,2,4-triazol-5-yl)-6-(trifluoromethyl)thieno[3,2-b]pyridine::3-thiophen-2-yl-2-(1H-1,2,4-triazol-5-yl)-6-(trifluoromethyl)thieno[3,2-b]pyridine::SR-01000759126-1::cid_1472003 Sphingosine 1-phosphate receptor 2 Homo sapiens 13920 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41618&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1472003 252622340 ZINC05757174 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77738 OC(=O)c1sc2cc(cnc2c1-c1ccco1)C(F)(F)F InChI=1S/C13H6F3NO3S/c14-13(15,16)6-4-8-10(17-5-6)9(7-2-1-3-20-7)11(21-8)12(18)19/h1-5H,(H,18,19) KZEPTKFBJWYCJD-UHFFFAOYSA-N 41619 3-(2-furanyl)-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxylic acid::3-(2-furyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid::3-(furan-2-yl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid::SR-01000759127-1::cid_1490062 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41619&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1490062 252622341 ZINC01405123 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77739 COC(=O)c1sc2cc(cnc2c1-c1cccs1)C(F)(F)F InChI=1S/C14H8F3NO2S2/c1-20-13(19)12-10(8-3-2-4-21-8)11-9(22-12)5-7(6-18-11)14(15,16)17/h2-6H,1H3 RCIRVWNMADHUIF-UHFFFAOYSA-N 41620 3-(2-thienyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid methyl ester::3-thiophen-2-yl-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxylic acid methyl ester::SR-01000759129-1::cid_1478927::methyl 3-thiophen-2-yl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylate Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41620&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1478927 252622342 ZINC01391624 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77740 FC(F)(F)c1cnc2c(csc2c1)-c1cccs1 InChI=1S/C12H6F3NS2/c13-12(14,15)7-4-10-11(16-5-7)8(6-18-10)9-2-1-3-17-9/h1-6H CHXUVLIATZSHGQ-UHFFFAOYSA-N 41621 3-(2-thienyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine::3-thiophen-2-yl-6-(trifluoromethyl)thieno[3,2-b]pyridine::SR-01000759131-1::cid_1486485 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41621&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1486485 252622343 ZINC01400639 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77741 Fc1ccc(NC(=O)c2cc(nc3ccccc23)-c2cccs2)cc1 InChI=1S/C20H13FN2OS/c21-13-7-9-14(10-8-13)22-20(24)16-12-18(19-6-3-11-25-19)23-17-5-2-1-4-15(16)17/h1-12H,(H,22,24) QSOYDLNLYHOQPB-UHFFFAOYSA-N 41622 N-(4-fluorophenyl)-2-(2-thienyl)cinchoninamide::N-(4-fluorophenyl)-2-thiophen-2-yl-4-quinolinecarboxamide::N-(4-fluorophenyl)-2-thiophen-2-yl-quinoline-4-carboxamide::N-(4-fluorophenyl)-2-thiophen-2-ylquinoline-4-carboxamide::SR-01000412716-2::cid_673633 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41622&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 673633 252622344 ZINC00035714 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77742 Fc1ccc(NC(=O)c2sc3cc(cnc3c2-c2cccs2)C(F)(F)F)cc1 InChI=1S/C19H10F4N2OS2/c20-11-3-5-12(6-4-11)25-18(26)17-15(13-2-1-7-27-13)16-14(28-17)8-10(9-24-16)19(21,22)23/h1-9H,(H,25,26) OILXMQDCLHYXBN-UHFFFAOYSA-N 41595 MLS000540468::N-(4-fluorophenyl)-3-(2-thienyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide::N-(4-fluorophenyl)-3-thiophen-2-yl-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxamide::N-(4-fluorophenyl)-3-thiophen-2-yl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide::SMR000125726::cid_2765371 Sphingosine 1-phosphate receptor 2 Homo sapiens 2063 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41595&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 2765371 252622320 ZINC08671981 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77743 COC(=O)c1sc2cc(cnc2c1-c1ccccc1)C(F)(F)F InChI=1S/C16H10F3NO2S/c1-22-15(21)14-12(9-5-3-2-4-6-9)13-11(23-14)7-10(8-20-13)16(17,18)19/h2-8H,1H3 YHAZXAGTJFKXOG-UHFFFAOYSA-N 41624 3-phenyl-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxylic acid methyl ester::3-phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid methyl ester::SR-01000678493-2::cid_1480204::methyl 3-phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylate Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41624&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1480204 252622345 ZINC01393122 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77744 COC(=O)c1sc2cc(cnc2c1-c1ccccn1)C(F)(F)F InChI=1S/C15H9F3N2O2S/c1-22-14(21)13-11(9-4-2-3-5-19-9)12-10(23-13)6-8(7-20-12)15(16,17)18/h2-7H,1H3 DEQDEIDIVREGPF-UHFFFAOYSA-N 41625 3-(2-pyridinyl)-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxylic acid methyl ester::3-(2-pyridyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid methyl ester::SR-01000755162-2::cid_1486478::methyl 3-pyridin-2-yl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylate Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41625&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1486478 252622346 ZINC01400632 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77745 Fc1ccc(NC(=O)c2sccc2S(=O)(=O)Cc2cccc(c2)C(F)(F)F)cc1 InChI=1S/C19H13F4NO3S2/c20-14-4-6-15(7-5-14)24-18(25)17-16(8-9-28-17)29(26,27)11-12-2-1-3-13(10-12)19(21,22)23/h1-10H,11H2,(H,24,25) RBCLFKLYLYJDDS-UHFFFAOYSA-N 41626 N-(4-fluorophenyl)-3-[3-(trifluoromethyl)benzyl]sulfonyl-thiophene-2-carboxamide::N-(4-fluorophenyl)-3-[[3-(trifluoromethyl)phenyl]methylsulfonyl]-2-thiophenecarboxamide::N-(4-fluorophenyl)-3-[[3-(trifluoromethyl)phenyl]methylsulfonyl]thiophene-2-carboxamide::SR-01000759124-1::cid_1480237 Sphingosine 1-phosphate receptor 2 Homo sapiens 18390 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41626&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1480237 252622347 ZINC01393162 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77746 OC(=O)c1sc2cc(cnc2c1-c1ccccn1)C(F)(F)F InChI=1S/C14H7F3N2O2S/c15-14(16,17)7-5-9-11(19-6-7)10(12(22-9)13(20)21)8-3-1-2-4-18-8/h1-6H,(H,20,21) KJEHNVDRRPVEOU-UHFFFAOYSA-N 41627 3-(2-pyridinyl)-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxylic acid::3-(2-pyridyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid::3-pyridin-2-yl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid::SR-01000726490-2::cid_1486480 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41627&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1486480 252622348 ZINC01400634 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77747 Cc1nc(sc1C(=O)Nc1ccc(F)cc1)-c1cccs1 InChI=1S/C15H11FN2OS2/c1-9-13(21-15(17-9)12-3-2-8-20-12)14(19)18-11-6-4-10(16)5-7-11/h2-8H,1H3,(H,18,19) LBVGOZDJTLSJCJ-UHFFFAOYSA-N 41628 N-(4-fluorophenyl)-4-methyl-2-(2-thienyl)thiazole-5-carboxamide::N-(4-fluorophenyl)-4-methyl-2-thiophen-2-yl-1,3-thiazole-5-carboxamide::N-(4-fluorophenyl)-4-methyl-2-thiophen-2-yl-5-thiazolecarboxamide::SR-01000759134-1::cid_7667820 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41628&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 7667820 252622349 ZINC05403565 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77748 Fc1ccc(NC(=O)c2cccs2)cc1 InChI=1S/C11H8FNOS/c12-8-3-5-9(6-4-8)13-11(14)10-2-1-7-15-10/h1-7H,(H,13,14) GCPZKOCHNSMRNY-UHFFFAOYSA-N 41629 N-(4-fluorophenyl)-2-thiophenecarboxamide::N-(4-fluorophenyl)thiophene-2-carboxamide::SR-01000392624-3::cid_531923 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41629&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 531923 252622350 ZINC00485164 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77749 OC(=O)c1sc2cc(cnc2c1-c1ccccc1)C(F)(F)F InChI=1S/C15H8F3NO2S/c16-15(17,18)9-6-10-12(19-7-9)11(13(22-10)14(20)21)8-4-2-1-3-5-8/h1-7H,(H,20,21) YTMOGPGAAGFVCE-UHFFFAOYSA-N 41630 3-phenyl-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxylic acid::3-phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid::SR-01000678935-2::cid_3751878 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41630&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 3751878 252622351 ZINC12960520 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77750 COC(=O)c1sc2cc(cnc2c1-c1cccnc1)C(F)(F)F InChI=1S/C15H9F3N2O2S/c1-22-14(21)13-11(8-3-2-4-19-6-8)12-10(23-13)5-9(7-20-12)15(16,17)18/h2-7H,1H3 QOOCDPCPQKGZOH-UHFFFAOYSA-N 41631 3-(3-pyridinyl)-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxylic acid methyl ester::3-(3-pyridyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid methyl ester::SR-01000688108-2::cid_5238869::methyl 3-pyridin-3-yl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylate Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41631&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 5238869 252622352 ZINC04052945 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77751 Fc1ccc(NC(=O)c2sc(nc2C(F)(F)F)-c2ccccc2)cc1 InChI=1S/C17H10F4N2OS/c18-11-6-8-12(9-7-11)22-15(24)13-14(17(19,20)21)23-16(25-13)10-4-2-1-3-5-10/h1-9H,(H,22,24) ULCUTEFVOFVXHD-UHFFFAOYSA-N 41632 N-(4-fluorophenyl)-2-phenyl-4-(trifluoromethyl)-1,3-thiazole-5-carboxamide::N-(4-fluorophenyl)-2-phenyl-4-(trifluoromethyl)-5-thiazolecarboxamide::N-(4-fluorophenyl)-2-phenyl-4-(trifluoromethyl)thiazole-5-carboxamide::SR-01000759128-1::cid_1473856 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41632&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1473856 252622353 ZINC01385575 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77752 OC(=O)c1sc2cc(cnc2c1-c1cccnc1)C(F)(F)F InChI=1S/C14H7F3N2O2S/c15-14(16,17)8-4-9-11(19-6-8)10(12(22-9)13(20)21)7-2-1-3-18-5-7/h1-6H,(H,20,21) UZOPBERKDRZFLE-UHFFFAOYSA-N 41633 3-(3-pyridinyl)-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxylic acid::3-(3-pyridyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid::3-pyridin-3-yl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid::SR-01000759130-1::cid_1486466 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41633&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 1486466 252622354 ZINC01400616 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77753 FC(F)(F)c1cnc2c(c(sc2c1)C(=O)N1CCOCC1)-c1ccccc1 InChI=1S/C19H15F3N2O2S/c20-19(21,22)13-10-14-16(23-11-13)15(12-4-2-1-3-5-12)17(27-14)18(25)24-6-8-26-9-7-24/h1-5,10-11H,6-9H2 KDGXQHFCILYIAG-UHFFFAOYSA-N 41634 4-morpholinyl-[3-phenyl-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinyl]methanone::SR-01000759132-1::cid_3613860::morpholin-4-yl-[3-phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl]methanone::morpholino-[3-phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl]methanone Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41634&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 3613860 252622355 ZINC04053996 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77754 CN(C)\C=N\C(=O)c1sc2cc(cnc2c1-c1ccccc1)C(F)(F)F InChI=1S/C18H14F3N3OS/c1-24(2)10-23-17(25)16-14(11-6-4-3-5-7-11)15-13(26-16)8-12(9-22-15)18(19,20)21/h3-10H,1-2H3/b23-10+ OCQVAMHRNGYEFE-AUEPDCJTSA-N 41635 N-(dimethylaminomethylene)-3-phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide::N-(dimethylaminomethylidene)-3-phenyl-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinecarboxamide::N-(dimethylaminomethylidene)-3-phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide::SR-01000759133-1::cid_3545772 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41635&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 3545772 252622356 ZINC04053999 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8 77755 Cc1ccsc1C(=O)Nc1ccc(F)cc1 InChI=1S/C12H10FNOS/c1-8-6-7-16-11(8)12(15)14-10-4-2-9(13)3-5-10/h2-7H,1H3,(H,14,15) JXQXEJDGWFKAMN-UHFFFAOYSA-N 41636 N-(4-fluorophenyl)-3-methyl-2-thiophenecarboxamide::N-(4-fluorophenyl)-3-methyl-thiophene-2-carboxamide::N-(4-fluorophenyl)-3-methylthiophene-2-carboxamide::SR-01000759135-1::cid_7947427 Sphingosine 1-phosphate receptor 2 Homo sapiens >30000 PubChem 10.7270/Q2B56H4Q aid851 PubChem, PC 12/19/2007 5/12/2011 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2333&target=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41636&enzyme=Sphingosine+1-phosphate+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 7947427 252622357 ZINC06340649 1 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV 7T6B Sphingosine 1-phosphate receptor 2 S1PR2_HUMAN O95136 Q86UN8