BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 714987 CC(C)COc1ccc(CN2Cc3cc(F)ccc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H34FN3O2/c1-19(2)18-32-25-8-4-20(5-9-25)15-29-16-22-14-23(27)7-6-21(22)17-30(26(29)31)24-10-12-28(3)13-11-24/h4-9,14,19,24H,10-13,15-18H2,1-3H3 XHEQIDLUDZOIOC-UHFFFAOYSA-N 793410 7-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19001 5-hydroxytryptamine receptor 2A Homo sapiens 0.028 US Patent 10.7270/Q2RB79KW aid1797849 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793410 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793410&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166492611 528824873 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 714988 CC(C)COc1ccc(CN2Cc3cc(F)ccc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H34FN3O2/c1-19(2)18-32-25-8-4-20(5-9-25)15-29-16-22-14-23(27)7-6-21(22)17-30(26(29)31)24-10-12-28(3)13-11-24/h4-9,14,19,24H,10-13,15-18H2,1-3H3 XHEQIDLUDZOIOC-UHFFFAOYSA-N 793410 7-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19001 5-hydroxytryptamine receptor 2C Homo sapiens 2.40 US Patent 10.7270/Q2RB79KW aid1797849 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793410 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793410&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 166492611 528824873 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 714989 CC(C)COc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H34FN3O2/c1-19(2)18-32-25-8-4-20(5-9-25)15-29-16-21-6-7-23(27)14-22(21)17-30(26(29)31)24-10-12-28(3)13-11-24/h4-9,14,19,24H,10-13,15-18H2,1-3H3 QVQBVAYWVGDTIT-UHFFFAOYSA-N 793414 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19005 5-hydroxytryptamine receptor 2A Homo sapiens 0.429 US Patent 10.7270/Q2RB79KW aid1797849 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793414 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793414&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166492602 528824877 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 714990 CC(C)COc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H34FN3O2/c1-19(2)18-32-25-8-4-20(5-9-25)15-29-16-21-6-7-23(27)14-22(21)17-30(26(29)31)24-10-12-28(3)13-11-24/h4-9,14,19,24H,10-13,15-18H2,1-3H3 QVQBVAYWVGDTIT-UHFFFAOYSA-N 793414 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19005 5-hydroxytryptamine receptor 2C Homo sapiens 3.39 US Patent 10.7270/Q2RB79KW aid1797849 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793414 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793414&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 166492602 528824877 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 714991 CN1CCC(N2Cc3cc(F)ccc3CN(Cc3ccc(OC4CC4)cc3)C2=O)CC1 InChI=1S/C25H30FN3O2/c1-27-12-10-22(11-13-27)29-17-20-14-21(26)5-4-19(20)16-28(25(29)30)15-18-2-6-23(7-3-18)31-24-8-9-24/h2-7,14,22,24H,8-13,15-17H2,1H3 RLRGMVVGFGEOEC-UHFFFAOYSA-N 793450 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(cyclopropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19006 5-hydroxytryptamine receptor 2A Homo sapiens 0.277 US Patent 10.7270/Q2RB79KW aid1797849 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793450 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793450&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166492598 528824913 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 714992 CN1CCC(N2Cc3cc(F)ccc3CN(Cc3ccc(OC4CC4)cc3)C2=O)CC1 InChI=1S/C25H30FN3O2/c1-27-12-10-22(11-13-27)29-17-20-14-21(26)5-4-19(20)16-28(25(29)30)15-18-2-6-23(7-3-18)31-24-8-9-24/h2-7,14,22,24H,8-13,15-17H2,1H3 RLRGMVVGFGEOEC-UHFFFAOYSA-N 793450 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(cyclopropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19006 5-hydroxytryptamine receptor 2C Homo sapiens 1.62 US Patent 10.7270/Q2RB79KW aid1797849 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793450 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793450&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 166492598 528824913 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 714993 CC(C)CNc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H35FN4O/c1-19(2)15-28-24-8-4-20(5-9-24)16-30-17-21-6-7-23(27)14-22(21)18-31(26(30)32)25-10-12-29(3)13-11-25/h4-9,14,19,25,28H,10-13,15-18H2,1-3H3 XVXBMKWJMYQWPV-UHFFFAOYSA-N 793451 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropylamino)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19007 5-hydroxytryptamine receptor 2A Homo sapiens 2.72 US Patent 10.7270/Q2RB79KW aid1797849 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793451 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793451&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166492619 528824914 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 714994 CC(C)CNc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H35FN4O/c1-19(2)15-28-24-8-4-20(5-9-24)16-30-17-21-6-7-23(27)14-22(21)18-31(26(30)32)25-10-12-29(3)13-11-25/h4-9,14,19,25,28H,10-13,15-18H2,1-3H3 XVXBMKWJMYQWPV-UHFFFAOYSA-N 793451 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropylamino)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19007 5-hydroxytryptamine receptor 2C Homo sapiens 27.3 US Patent 10.7270/Q2RB79KW aid1797849 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793451 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793451&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 166492619 528824914 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 714995 CC(C)Cc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H34FN3O/c1-19(2)14-20-4-6-21(7-5-20)16-29-17-22-8-9-24(27)15-23(22)18-30(26(29)31)25-10-12-28(3)13-11-25/h4-9,15,19,25H,10-14,16-18H2,1-3H3 XZNSRFVAYANENW-UHFFFAOYSA-N 793452 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropyl)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19008 5-hydroxytryptamine receptor 2A Homo sapiens 5.29 US Patent 10.7270/Q2RB79KW aid1797849 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793452 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793452&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166492592 528824915 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 714996 CC(C)Cc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H34FN3O/c1-19(2)14-20-4-6-21(7-5-20)16-29-17-22-8-9-24(27)15-23(22)18-30(26(29)31)25-10-12-28(3)13-11-25/h4-9,15,19,25H,10-14,16-18H2,1-3H3 XZNSRFVAYANENW-UHFFFAOYSA-N 793452 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropyl)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19008 5-hydroxytryptamine receptor 2C Homo sapiens 42.4 US Patent 10.7270/Q2RB79KW aid1797849 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793452 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793452&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 166492592 528824915 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 714997 COc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C23H28FN3O2/c1-25-11-9-21(10-12-25)27-16-19-13-20(24)6-5-18(19)15-26(23(27)28)14-17-3-7-22(29-2)8-4-17/h3-8,13,21H,9-12,14-16H2,1-2H3 RTKODVSVKDFIFK-UHFFFAOYSA-N 793453 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[(4-methoxyphenyl)methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19009 5-hydroxytryptamine receptor 2A Homo sapiens 2.99 US Patent 10.7270/Q2RB79KW aid1797849 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793453 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793453&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166492594 528824916 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715342 COc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C23H28FN3O2/c1-25-11-9-21(10-12-25)27-16-19-13-20(24)6-5-18(19)15-26(23(27)28)14-17-3-7-22(29-2)8-4-17/h3-8,13,21H,9-12,14-16H2,1-2H3 RTKODVSVKDFIFK-UHFFFAOYSA-N 793453 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[(4-methoxyphenyl)methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19009 5-hydroxytryptamine receptor 2C Homo sapiens 2.03 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793453 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793453&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 166492594 528824916 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 715344 CC(C)Oc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)c(F)c1 InChI=1S/C25H31F2N3O2/c1-17(2)32-23-7-5-19(24(27)13-23)15-29-14-18-4-6-21(26)12-20(18)16-30(25(29)31)22-8-10-28(3)11-9-22/h4-7,12-13,17,22H,8-11,14-16H2,1-3H3 SOPZAOYUAXFBRY-UHFFFAOYSA-N 793454 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[2-fluoro-4-(isopropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19011 5-hydroxytryptamine receptor 2A Homo sapiens 12.7 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793454 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793454&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166818564 528824917 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715346 CC(C)Oc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)cc1F InChI=1S/C25H31F2N3O2/c1-17(2)32-24-7-4-18(12-23(24)27)14-29-15-19-5-6-21(26)13-20(19)16-30(25(29)31)22-8-10-28(3)11-9-22/h4-7,12-13,17,22H,8-11,14-16H2,1-3H3 AGYLXKIAIUYRIL-UHFFFAOYSA-N 793455 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[3-fluoro-4-(isopropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19012 5-hydroxytryptamine receptor 2A Homo sapiens 0.947 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793455 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793455&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166819367 528824918 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715348 CC(C)Oc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)cc1F InChI=1S/C25H31F2N3O2/c1-17(2)32-24-7-4-18(12-23(24)27)14-29-15-19-5-6-21(26)13-20(19)16-30(25(29)31)22-8-10-28(3)11-9-22/h4-7,12-13,17,22H,8-11,14-16H2,1-3H3 AGYLXKIAIUYRIL-UHFFFAOYSA-N 793455 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[3-fluoro-4-(isopropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19012 5-hydroxytryptamine receptor 2C Homo sapiens 9.36 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793455 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793455&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 166819367 528824918 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 715350 CC(C)Oc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)cn1 InChI=1S/C24H31FN4O2/c1-17(2)31-23-7-4-18(13-26-23)14-28-15-19-5-6-21(25)12-20(19)16-29(24(28)30)22-8-10-27(3)11-9-22/h4-7,12-13,17,22H,8-11,14-16H2,1-3H3 JUFDZMNGOYOFGF-UHFFFAOYSA-N 793456 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[(6-isopropoxy)pyridin-3-yl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19013 5-hydroxytryptamine receptor 2A Homo sapiens 9.78 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793456 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793456&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166819103 528824919 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715352 CC(C)COc1ccc(CN2Cc3ccc(F)cc3CN([C@H]3CCN(C)C[C@H]3F)C2=O)cc1 InChI=1S/C26H33F2N3O2/c1-18(2)17-33-23-8-4-19(5-9-23)13-30-14-20-6-7-22(27)12-21(20)15-31(26(30)32)25-10-11-29(3)16-24(25)28/h4-9,12,18,24-25H,10-11,13-17H2,1-3H3 DRQGYNRFTLZHNE-UHFFFAOYSA-N 793457 (3R,4S)-8-fluoro-2-(1-methyl-3-fluoropiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19014-0 5-hydroxytryptamine receptor 2A Homo sapiens 4.19 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793457 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793457&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 168144861 528824920 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715354 CC(C)COc1ccc(CN2Cc3ccc(F)cc3CN([C@H]3CCN(C)C[C@H]3F)C2=O)cc1 InChI=1S/C26H33F2N3O2/c1-18(2)17-33-23-8-4-19(5-9-23)13-30-14-20-6-7-22(27)12-21(20)15-31(26(30)32)25-10-11-29(3)16-24(25)28/h4-9,12,18,24-25H,10-11,13-17H2,1-3H3 DRQGYNRFTLZHNE-UHFFFAOYSA-N 793457 (3R,4S)-8-fluoro-2-(1-methyl-3-fluoropiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19014-0 5-hydroxytryptamine receptor 2C Homo sapiens 0.200 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793457 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793457&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 168144861 528824920 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 715356 CC(C)COc1ccc(CN2Cc3ccc(F)cc3CN(c3ccn(C)c3)C2=O)cc1 InChI=1S/C25H28FN3O2/c1-18(2)17-31-24-8-4-19(5-9-24)13-28-14-20-6-7-22(26)12-21(20)15-29(25(28)30)23-10-11-27(3)16-23/h4-12,16,18H,13-15,17H2,1-3H3 RKQRSGVVERKQNR-UHFFFAOYSA-N 793458 8-fluoro-2-(1-methylpyrrol-3-yl)-4-[[(4-isobutoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19015 5-hydroxytryptamine receptor 2A Homo sapiens 1.69 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793458 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793458&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 168144862 528824921 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715358 CC(C)COc1ccc(CN2Cc3ccc(F)cc3CN(c3ccn(C)c3)C2=O)cc1 InChI=1S/C25H28FN3O2/c1-18(2)17-31-24-8-4-19(5-9-24)13-28-14-20-6-7-22(26)12-21(20)15-29(25(28)30)23-10-11-27(3)16-23/h4-12,16,18H,13-15,17H2,1-3H3 RKQRSGVVERKQNR-UHFFFAOYSA-N 793458 8-fluoro-2-(1-methylpyrrol-3-yl)-4-[[(4-isobutoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19015 5-hydroxytryptamine receptor 2C Homo sapiens 0.410 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793458 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793458&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 168144862 528824921 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 715360 CC(C)COc1ccc(CN2Cc3cc(Cl)ccc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H34ClN3O2/c1-19(2)18-32-25-8-4-20(5-9-25)15-29-16-22-14-23(27)7-6-21(22)17-30(26(29)31)24-10-12-28(3)13-11-24/h4-9,14,19,24H,10-13,15-18H2,1-3H3 FCLXFDGJWAZTIX-UHFFFAOYSA-N 793459 7-chloro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A190017 5-hydroxytryptamine receptor 2A Homo sapiens 1.63 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793459 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793459&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166492618 528824922 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715362 CC(C)COc1ccc(CN2Cc3cc(Cl)ccc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H34ClN3O2/c1-19(2)18-32-25-8-4-20(5-9-25)15-29-16-22-14-23(27)7-6-21(22)17-30(26(29)31)24-10-12-28(3)13-11-24/h4-9,14,19,24H,10-13,15-18H2,1-3H3 FCLXFDGJWAZTIX-UHFFFAOYSA-N 793459 7-chloro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A190017 5-hydroxytryptamine receptor 2C Homo sapiens 486 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793459 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793459&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 166492618 528824922 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 715364 CC(C)COc1ccc(CN2Cc3ccc(F)cc3CC3(CCN(C)CC3)C2=O)cc1 InChI=1S/C26H33FN2O2/c1-19(2)18-31-24-8-4-20(5-9-24)16-29-17-21-6-7-23(27)14-22(21)15-26(25(29)30)10-12-28(3)13-11-26/h4-9,14,19H,10-13,15-18H2,1-3H3 KDQHITNPXVYQGQ-UHFFFAOYSA-N 793460 7-fluoro-1'-methyl-2-[[4-(2-methylpropoxy)phenyl]methyl]-1,2-dihydrospiro[benzo[c]azepine-4,4'-piperidine]-3(5H)-one::US12559471, Compound NH-K-A19019 5-hydroxytryptamine receptor 2A Homo sapiens 53.3 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793460 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793460&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 163704232 528824923 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715366 CC(C)COc1ccc(CN2Cc3ccccc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H35N3O2/c1-20(2)19-31-25-10-8-21(9-11-25)16-28-17-22-6-4-5-7-23(22)18-29(26(28)30)24-12-14-27(3)15-13-24/h4-11,20,24H,12-19H2,1-3H3 FTZVALJDQRHTBF-UHFFFAOYSA-N 793461 2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19020 5-hydroxytryptamine receptor 2A Homo sapiens 1.74 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793461 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793461&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166492609 528824924 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715368 CC(C)COc1ccc(CN2Cc3ccc(F)cc3CN([C@H]3CCN(C)C[C@@H]3F)C2=O)cc1 InChI=1S/C26H33F2N3O2/c1-18(2)17-33-23-8-4-19(5-9-23)13-30-14-20-6-7-22(27)12-21(20)15-31(26(30)32)25-10-11-29(3)16-24(25)28/h4-9,12,18,24-25H,10-11,13-17H2,1-3H3 DRQGYNRFTLZHNE-UHFFFAOYSA-N 793462 (3S,4S)-8-fluoro-2-(1-methyl-3-fluoropiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19014-0A 5-hydroxytryptamine receptor 2A Homo sapiens 0.002 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793462 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793462&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 176887409 528824925 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715370 CC(C)COc1ccc(CN2Cc3ccc(F)cc3CN([C@H]3CCN(C)C[C@@H]3F)C2=O)cc1 InChI=1S/C26H33F2N3O2/c1-18(2)17-33-23-8-4-19(5-9-23)13-30-14-20-6-7-22(27)12-21(20)15-31(26(30)32)25-10-11-29(3)16-24(25)28/h4-9,12,18,24-25H,10-11,13-17H2,1-3H3 DRQGYNRFTLZHNE-UHFFFAOYSA-N 793462 (3S,4S)-8-fluoro-2-(1-methyl-3-fluoropiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19014-0A 5-hydroxytryptamine receptor 2C Homo sapiens 26.1 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793462 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793462&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 176887409 528824925 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 715372 CC(C)COc1ccc(CN2Cc3cc(F)c(F)cc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H33F2N3O2/c1-18(2)17-33-23-6-4-19(5-7-23)14-30-15-20-12-24(27)25(28)13-21(20)16-31(26(30)32)22-8-10-29(3)11-9-22/h4-7,12-13,18,22H,8-11,14-17H2,1-3H3 YQAOECWKGJVRRM-UHFFFAOYSA-N 793463 7,8-difluoro-2-(4-isobutoxybenzyl)-4-(1-methylpiperidin-4-yl)-1,2,4,5-tetrahydro-3H-benzo[e][1,3]diazepin-3-one::US12559471, Compound NH-K-A20001 5-hydroxytryptamine receptor 2A Homo sapiens 5.98 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793463 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793463&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166492603 528824926 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715374 CN1CCC(N2Cc3cc(F)ccc3CN(Cc3ccc(CC(C)(C)O)cc3)C2=O)CC1 InChI=1S/C26H34FN3O2/c1-26(2,32)15-19-4-6-20(7-5-19)16-29-17-21-8-9-23(27)14-22(21)18-30(25(29)31)24-10-12-28(3)13-11-24/h4-9,14,24,32H,10-13,15-18H2,1-3H3 RGLDCXGLHXDYRP-UHFFFAOYSA-N 793464 7-fluoro-2-[[4-(2-hydroxy-2-methylpropyl)phenyl]methyl]-4-(1-methylpiperidin-4-yl)-1,5-dihydro-2,4-benzodiazepin-3-one::US12559471, Compound NH-K-A19010 5-hydroxytryptamine receptor 2A Homo sapiens 20.1 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793464 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793464&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166492613 528824927 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715376 CN1CCC(N2Cc3cc(F)ccc3CN(Cc3ccc(CC(C)(C)O)cc3)C2=O)CC1 InChI=1S/C26H34FN3O2/c1-26(2,32)15-19-4-6-20(7-5-19)16-29-17-21-8-9-23(27)14-22(21)18-30(25(29)31)24-10-12-28(3)13-11-24/h4-9,14,24,32H,10-13,15-18H2,1-3H3 RGLDCXGLHXDYRP-UHFFFAOYSA-N 793464 7-fluoro-2-[[4-(2-hydroxy-2-methylpropyl)phenyl]methyl]-4-(1-methylpiperidin-4-yl)-1,5-dihydro-2,4-benzodiazepin-3-one::US12559471, Compound NH-K-A19010 5-hydroxytryptamine receptor 2C Homo sapiens 18.2 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793464 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793464&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 166492613 528824927 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 715378 CN1CCC(N2Cc3ccc(F)cc3CN(Cc3ccc(OC4CC4)cc3)C2=O)CC1 InChI=1S/C25H30FN3O2/c1-27-12-10-22(11-13-27)29-17-19-4-5-21(26)14-20(19)16-28(25(29)30)15-18-2-6-23(7-3-18)31-24-8-9-24/h2-7,14,22,24H,8-13,15-17H2,1H3 MJMJVUKFAWIZJI-UHFFFAOYSA-N 793465 4-[(4-cyclopropoxyphenyl)methyl]-7-fluoro-2-(1-methylpiperidin-4-yl)-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19022 5-hydroxytryptamine receptor 2A Homo sapiens 0.150 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793465 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793465&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search 166492600 528824928 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715380 CN1CCC(N2Cc3ccc(F)cc3CN(Cc3ccc(OC4CC4)cc3)C2=O)CC1 InChI=1S/C25H30FN3O2/c1-27-12-10-22(11-13-27)29-17-19-4-5-21(26)14-20(19)16-28(25(29)30)15-18-2-6-23(7-3-18)31-24-8-9-24/h2-7,14,22,24H,8-13,15-17H2,1H3 MJMJVUKFAWIZJI-UHFFFAOYSA-N 793465 4-[(4-cyclopropoxyphenyl)methyl]-7-fluoro-2-(1-methylpiperidin-4-yl)-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19022 5-hydroxytryptamine receptor 2C Homo sapiens 1.33 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793465 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793465&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search 166492600 528824928 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 715382 CC(C)COc1ccc(cc1)CNC(=O)N(Cc2ccc(cc2)F)C3CCN(CC3)C InChI=1S/C25H34FN3O2/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21/h4-11,19,23H,12-18H2,1-3H3,(H,27,30) RKEWSXXUOLRFBX-UHFFFAOYSA-N 139370 ACP-103::Pimavanserin::Pimavanserin hydrochloride::Nuplazid::Pimavanserin tartrate::bis(1-(4-fluorobenzyl)-1-(1-methylpiperidin-4-yl)-3-(4-(2-methylpropoxy)benzyl)urea) (2R,3R)-2,3-dihydroxybutanedioate::WO2023288027, Cmpd PIMA::US20230348421, Compound Pimavanserin::US12559471, Compound Pimavanserin 5-hydroxytryptamine receptor 2A Homo sapiens 0.036 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139370 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=687&target=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139370&enzyme=5-hydroxytryptamine+receptor+2A&column=ki&startPg=0&Increment=50&submit=Search A1L11 8ZMG,9UJM 10071196 249870692 DB05316 1 MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV 9LLB,9LLA,9LL9,9LL8,9LL7,9ASA,9AS9,9AS8,9AS7,9AS6,9AS5,9AS4,9AS3,9AS2,9AS1,9AS0,9ARZ,9ARY,9ARX,6WHA,8V6U,8UWL,7RAN 5-hydroxytryptamine receptor 2A 5HT2A_HUMAN P28223 B2RAC5 B4DZ79 F5GWE8 Q5T8C0 715384 CC(C)COc1ccc(cc1)CNC(=O)N(Cc2ccc(cc2)F)C3CCN(CC3)C InChI=1S/C25H34FN3O2/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21/h4-11,19,23H,12-18H2,1-3H3,(H,27,30) RKEWSXXUOLRFBX-UHFFFAOYSA-N 139370 ACP-103::Pimavanserin::Pimavanserin hydrochloride::Nuplazid::Pimavanserin tartrate::bis(1-(4-fluorobenzyl)-1-(1-methylpiperidin-4-yl)-3-(4-(2-methylpropoxy)benzyl)urea) (2R,3R)-2,3-dihydroxybutanedioate::WO2023288027, Cmpd PIMA::US20230348421, Compound Pimavanserin::US12559471, Compound Pimavanserin 5-hydroxytryptamine receptor 2C Homo sapiens 2.94 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139370 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3430&target=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139370&enzyme=5-hydroxytryptamine+receptor+2C&column=ki&startPg=0&Increment=50&submit=Search A1L11 8ZMG,9UJM 10071196 249870692 DB05316 1 MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 8DPI,8DPH,9UGL 5-hydroxytryptamine receptor 2C 5HT2C_HUMAN P28335 B1AMW4 Q5VUF8 Q9NP28 715386 CC(C)COc1ccc(CN2Cc3cc(F)ccc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H34FN3O2/c1-19(2)18-32-25-8-4-20(5-9-25)15-29-16-22-14-23(27)7-6-21(22)17-30(26(29)31)24-10-12-28(3)13-11-24/h4-9,14,19,24H,10-13,15-18H2,1-3H3 XHEQIDLUDZOIOC-UHFFFAOYSA-N 793410 7-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19001 Potassium voltage-gated channel subfamily H member 2 Homo sapiens 260 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793410 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793410&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search 166492611 528824873 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS 8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G Voltage-gated inwardly rectifying potassium channel KCNH2 KCNH2_HUMAN Q12809 A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0 N/A A0A090N8Q0 715388 CC(C)COc1ccc(CN2Cc3ccc(F)cc3CN(C3CCN(C)CC3)C2=O)cc1 InChI=1S/C26H34FN3O2/c1-19(2)18-32-25-8-4-20(5-9-25)15-29-16-21-6-7-23(27)14-22(21)17-30(26(29)31)24-10-12-28(3)13-11-24/h4-9,14,19,24H,10-13,15-18H2,1-3H3 QVQBVAYWVGDTIT-UHFFFAOYSA-N 793414 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19005 Potassium voltage-gated channel subfamily H member 2 Homo sapiens 3173 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793414 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793414&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search 166492602 528824877 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS 8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G Voltage-gated inwardly rectifying potassium channel KCNH2 KCNH2_HUMAN Q12809 A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0 N/A A0A090N8Q0 715390 CN1CCC(N2Cc3cc(F)ccc3CN(Cc3ccc(OC4CC4)cc3)C2=O)CC1 InChI=1S/C25H30FN3O2/c1-27-12-10-22(11-13-27)29-17-20-14-21(26)5-4-19(20)16-28(25(29)30)15-18-2-6-23(7-3-18)31-24-8-9-24/h2-7,14,22,24H,8-13,15-17H2,1H3 RLRGMVVGFGEOEC-UHFFFAOYSA-N 793450 8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(cyclopropoxy)phenyl]methyl]-1,5-dihydro-2,4-benzodiazepine-3-one::US12559471, Compound NH-K-A19006 Potassium voltage-gated channel subfamily H member 2 Homo sapiens 1194 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793450 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793450&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search 166492598 528824913 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS 8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G Voltage-gated inwardly rectifying potassium channel KCNH2 KCNH2_HUMAN Q12809 A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0 N/A A0A090N8Q0 715392 CC(C)COc1ccc(cc1)CNC(=O)N(Cc2ccc(cc2)F)C3CCN(CC3)C InChI=1S/C25H34FN3O2/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21/h4-11,19,23H,12-18H2,1-3H3,(H,27,30) RKEWSXXUOLRFBX-UHFFFAOYSA-N 139370 ACP-103::Pimavanserin::Pimavanserin hydrochloride::Nuplazid::Pimavanserin tartrate::bis(1-(4-fluorobenzyl)-1-(1-methylpiperidin-4-yl)-3-(4-(2-methylpropoxy)benzyl)urea) (2R,3R)-2,3-dihydroxybutanedioate::WO2023288027, Cmpd PIMA::US20230348421, Compound Pimavanserin::US12559471, Compound Pimavanserin Potassium voltage-gated channel subfamily H member 2 Homo sapiens 208 US Patent 10.7270/Q2RB79KW aid1797861 US12559471 Xu, X; Qiu, Y; Guo, Q; Yu, M; Zhao, S; Li, Q; Jing, P; Hou, Y; Dong, Y; Wu, G; Zhang, S; Lu, A 2/24/2026 7/6/2026 Jiangsu Nhwa Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139370 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139370&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search A1L11 8ZMG,9UJM 10071196 249870692 DB05316 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS 8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G Voltage-gated inwardly rectifying potassium channel KCNH2 KCNH2_HUMAN Q12809 A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0 N/A A0A090N8Q0