BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
728844	N#Cc1ccc(N2CCN(C(=O)c3cccc(Cc4n[nH]c(=O)c5ccc(O)cc45)c3)CC2)nc1	InChI=1S/C26H22N6O3/c27-15-18-4-7-24(28-16-18)31-8-10-32(11-9-31)26(35)19-3-1-2-17(12-19)13-23-22-14-20(33)5-6-21(22)25(34)30-29-23/h1-7,12,14,16,33H,8-11,13H2,(H,30,34)	RKPRVCUSTLBVIP-UHFFFAOYSA-N	793493	US20260055079, Example 1	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793493	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793493&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220118	528824956							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728845	N#Cc1ccc(N2CCN(C(=O)c3cccc(Cc4n[nH]c(=O)c5ccc(O)cc45)c3)CC2)nc1	InChI=1S/C26H22N6O3/c27-15-18-4-7-24(28-16-18)31-8-10-32(11-9-31)26(35)19-3-1-2-17(12-19)13-23-22-14-20(33)5-6-21(22)25(34)30-29-23/h1-7,12,14,16,33H,8-11,13H2,(H,30,34)	RKPRVCUSTLBVIP-UHFFFAOYSA-N	793493	US20260055079, Example 1	Poly [ADP-ribose] polymerase 2	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793493	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793493&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220118	528824956							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728846	N#Cc1ccc(N2CCN(C(=O)c3cccc(Cc4n[nH]c(=O)c5ccc(Oc6ccccc6)cc45)c3)CC2)nc1	InChI=1S/C32H26N6O3/c33-20-23-9-12-30(34-21-23)37-13-15-38(16-14-37)32(40)24-6-4-5-22(17-24)18-29-28-19-26(41-25-7-2-1-3-8-25)10-11-27(28)31(39)36-35-29/h1-12,17,19,21H,13-16,18H2,(H,36,39)	CYYHMHUCESFFGU-UHFFFAOYSA-N	793496	US20260055079, Example 2	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793496	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793496&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220140	528824959							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728847	C#CCOc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C29H23FN6O3/c1-2-13-39-21-5-6-22-23(16-21)26(33-34-28(22)37)15-19-3-7-25(30)24(14-19)29(38)36-11-9-35(10-12-36)27-8-4-20(17-31)18-32-27/h1,3-8,14,16,18H,9-13,15H2,(H,34,37)	LDBQEJVSPQEQFS-UHFFFAOYSA-N	793497	US20260055079, Example 3	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793497	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793497&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219800	528824960							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728848	C#CCOc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C29H23FN6O3/c1-2-13-39-21-5-6-22-23(16-21)26(33-34-28(22)37)15-19-3-7-25(30)24(14-19)29(38)36-11-9-35(10-12-36)27-8-4-20(17-31)18-32-27/h1,3-8,14,16,18H,9-13,15H2,(H,34,37)	LDBQEJVSPQEQFS-UHFFFAOYSA-N	793497	US20260055079, Example 3	Poly [ADP-ribose] polymerase 2	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793497	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793497&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219800	528824960							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728849	COc1ccc2c(=O)[nH]nc(Cc3cccc(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C27H24N6O3/c1-36-21-6-7-22-23(15-21)24(30-31-26(22)34)14-18-3-2-4-20(13-18)27(35)33-11-9-32(10-12-33)25-8-5-19(16-28)17-29-25/h2-8,13,15,17H,9-12,14H2,1H3,(H,31,34)	DLRSYPKNUOLQHH-UHFFFAOYSA-N	793498	US20260055079, Example 4	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793498	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793498&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219863	528824961							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728850	N#Cc1ccc(N2CCN(C(=O)c3cccc(Cc4n[nH]c(=O)c5ccc(Cl)cc45)c3)CC2)nc1	InChI=1S/C26H21ClN6O2/c27-20-5-6-21-22(14-20)23(30-31-25(21)34)13-17-2-1-3-19(12-17)26(35)33-10-8-32(9-11-33)24-7-4-18(15-28)16-29-24/h1-7,12,14,16H,8-11,13H2,(H,31,34)	RHKUWKHBYWQCCY-UHFFFAOYSA-N	793499	US20260055079, Example 5	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793499	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793499&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219953	528824962							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728851	N#Cc1ccc(N2CCN(C(=O)c3cccc(Cc4n[nH]c(=O)c5ccc(F)cc45)c3)CC2)nc1	InChI=1S/C26H21FN6O2/c27-20-5-6-21-22(14-20)23(30-31-25(21)34)13-17-2-1-3-19(12-17)26(35)33-10-8-32(9-11-33)24-7-4-18(15-28)16-29-24/h1-7,12,14,16H,8-11,13H2,(H,31,34)	LVKCORULWCFTDV-UHFFFAOYSA-N	793500	US20260055079, Example 6	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793500	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793500&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220103	528824963							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728852	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OCC6CC6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H27FN6O3/c31-26-7-3-20(14-27-24-15-22(40-18-19-1-2-19)5-6-23(24)29(38)35-34-27)13-25(26)30(39)37-11-9-36(10-12-37)28-8-4-21(16-32)17-33-28/h3-8,13,15,17,19H,1-2,9-12,14,18H2,(H,35,38)	QIRGLLRUIDCSAB-UHFFFAOYSA-N	793501	US20260055079, Example 7	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793501	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793501&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220398	528824964							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728853	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OCC6CC6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H27FN6O3/c31-26-7-3-20(14-27-24-15-22(40-18-19-1-2-19)5-6-23(24)29(38)35-34-27)13-25(26)30(39)37-11-9-36(10-12-37)28-8-4-21(16-32)17-33-28/h3-8,13,15,17,19H,1-2,9-12,14,18H2,(H,35,38)	QIRGLLRUIDCSAB-UHFFFAOYSA-N	793501	US20260055079, Example 7	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793501	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793501&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220398	528824964							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728854	C#CC(C)Oc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C30H25FN6O3/c1-3-19(2)40-22-6-7-23-24(16-22)27(34-35-29(23)38)15-20-4-8-26(31)25(14-20)30(39)37-12-10-36(11-13-37)28-9-5-21(17-32)18-33-28/h1,4-9,14,16,18-19H,10-13,15H2,2H3,(H,35,38)	UNTGUEUITCLRIX-UHFFFAOYSA-N	793502	US20260055079, Example 8	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793502	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793502&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220276	528824965							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728855	C#CC(C)Oc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C30H25FN6O3/c1-3-19(2)40-22-6-7-23-24(16-22)27(34-35-29(23)38)15-20-4-8-26(31)25(14-20)30(39)37-12-10-36(11-13-37)28-9-5-21(17-32)18-33-28/h1,4-9,14,16,18-19H,10-13,15H2,2H3,(H,35,38)	UNTGUEUITCLRIX-UHFFFAOYSA-N	793502	US20260055079, Example 8	Poly [ADP-ribose] polymerase 1	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793502	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=232&target=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793502&enzyme=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search			169220276	528824965							1	MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW	9MJA,9MI8,4OQB,4OQA,4OPX,4DQY,8G0H,7S6M,7S6H,5A00,4ZZZ,4XHU,6XVW,5HA9,4PJT,2RCW,1WOK,1UK1,1UK0,6I8T,6I8M,7S81,7S68,6M3I,9DMC,9BPY,8FZ1,8FYZ,8FYY,6NTU,6NRJ,6NRI,6NRH,6NRG,6NRF,6BHV,5DS3,8U4W,2N8A,2RIQ,2JVN,2CR9,2CS2,2L31,2L30,3ODE,3ODC,7SCZ,7SCY,3ODA,3OD8,2DMJ,9UMC,9UMF	Poly [ADP-ribose] polymerase 1	PARP1_HUMAN	P09874	B1ANJ4 Q8IUZ9			N/A	A0A024R3T8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
728856	C#CC(C)Oc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C30H25FN6O3/c1-3-19(2)40-22-6-7-23-24(16-22)27(34-35-29(23)38)15-20-4-8-26(31)25(14-20)30(39)37-12-10-36(11-13-37)28-9-5-21(17-32)18-33-28/h1,4-9,14,16,18-19H,10-13,15H2,2H3,(H,35,38)	UNTGUEUITCLRIX-UHFFFAOYSA-N	793502	US20260055079, Example 8	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793502	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793502&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220276	528824965							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728857	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OCC(F)(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C28H22F4N6O3/c29-23-5-1-17(12-24-21-13-19(41-16-28(30,31)32)3-4-20(21)26(39)36-35-24)11-22(23)27(40)38-9-7-37(8-10-38)25-6-2-18(14-33)15-34-25/h1-6,11,13,15H,7-10,12,16H2,(H,36,39)	YEDMQRZYPKZQTK-UHFFFAOYSA-N	793503	US20260055079, Example 9	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793503&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220283	528824966							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728858	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C29H23FN6O2/c1-2-3-19-4-7-22-23(14-19)26(33-34-28(22)37)16-20-5-8-25(30)24(15-20)29(38)36-12-10-35(11-13-36)27-9-6-21(17-31)18-32-27/h4-9,14-15,18H,10-13,16H2,1H3,(H,34,37)	DOQGBJFQXSVRPN-UHFFFAOYSA-N	793504	US20260055079, Example 10	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793504	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793504&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220352	528824967							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728859	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C29H23FN6O2/c1-2-3-19-4-7-22-23(14-19)26(33-34-28(22)37)16-20-5-8-25(30)24(15-20)29(38)36-12-10-35(11-13-36)27-9-6-21(17-31)18-32-27/h4-9,14-15,18H,10-13,16H2,1H3,(H,34,37)	DOQGBJFQXSVRPN-UHFFFAOYSA-N	793504	US20260055079, Example 10	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793504	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793504&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220352	528824967							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728860	COC1CN(c2ccc3c(=O)[nH]nc(Cc4ccc(F)c(C(=O)N5CCN(c6ccc(C#N)cn6)CC5)c4)c3c2)C1	InChI=1S/C30H28FN7O3/c1-41-22-17-38(18-22)21-4-5-23-24(14-21)27(34-35-29(23)39)13-19-2-6-26(31)25(12-19)30(40)37-10-8-36(9-11-37)28-7-3-20(15-32)16-33-28/h2-7,12,14,16,22H,8-11,13,17-18H2,1H3,(H,35,39)	ZRVJTCUQNCXVRB-UHFFFAOYSA-N	793505	US20260055079, Example 11	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793505	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793505&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220165	528824968							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728861	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(NC6CC6)cc45)ccc3F)CC2)nc1	InChI=1S/C29H26FN7O2/c30-25-7-1-18(14-26-23-15-21(33-20-3-4-20)5-6-22(23)28(38)35-34-26)13-24(25)29(39)37-11-9-36(10-12-37)27-8-2-19(16-31)17-32-27/h1-2,5-8,13,15,17,20,33H,3-4,9-12,14H2,(H,35,38)	IEVNEYPFTJPSOC-UHFFFAOYSA-N	793506	US20260055079, Example 12	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793506	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793506&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220189	528824969							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728862	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CC6)cc45)ccc3F)CC2)nc1	InChI=1S/C29H25FN6O3/c30-25-7-1-18(14-26-23-15-21(39-20-3-4-20)5-6-22(23)28(37)34-33-26)13-24(25)29(38)36-11-9-35(10-12-36)27-8-2-19(16-31)17-32-27/h1-2,5-8,13,15,17,20H,3-4,9-12,14H2,(H,34,37)	ISWUUFRLLQVUHA-UHFFFAOYSA-N	793507	US20260055079, Example 13	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793507	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793507&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219809	528824970							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728863	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CC6)cc45)ccc3F)CC2)nc1	InChI=1S/C29H25FN6O3/c30-25-7-1-18(14-26-23-15-21(39-20-3-4-20)5-6-22(23)28(37)34-33-26)13-24(25)29(38)36-11-9-35(10-12-36)27-8-2-19(16-31)17-32-27/h1-2,5-8,13,15,17,20H,3-4,9-12,14H2,(H,34,37)	ISWUUFRLLQVUHA-UHFFFAOYSA-N	793507	US20260055079, Example 13	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793507	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793507&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219809	528824970							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728864	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H27FN6O3/c31-26-8-4-19(15-27-24-16-22(40-21-2-1-3-21)6-7-23(24)29(38)35-34-27)14-25(26)30(39)37-12-10-36(11-13-37)28-9-5-20(17-32)18-33-28/h4-9,14,16,18,21H,1-3,10-13,15H2,(H,35,38)	KUIRHPOTFYLAQE-UHFFFAOYSA-N	793508	US20260055079, Example 14	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793508	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793508&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220417	528824971							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728865	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H27FN6O3/c31-26-8-4-19(15-27-24-16-22(40-21-2-1-3-21)6-7-23(24)29(38)35-34-27)14-25(26)30(39)37-12-10-36(11-13-37)28-9-5-20(17-32)18-33-28/h4-9,14,16,18,21H,1-3,10-13,15H2,(H,35,38)	KUIRHPOTFYLAQE-UHFFFAOYSA-N	793508	US20260055079, Example 14	Poly [ADP-ribose] polymerase 2	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793508	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793508&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220417	528824971							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728866	C#CCNc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C29H24FN7O2/c1-2-9-32-21-5-6-22-23(16-21)26(34-35-28(22)38)15-19-3-7-25(30)24(14-19)29(39)37-12-10-36(11-13-37)27-8-4-20(17-31)18-33-27/h1,3-8,14,16,18,32H,9-13,15H2,(H,35,38)	YZVHMXLGPXLFMK-UHFFFAOYSA-N	793509	US20260055079, Example 15	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793509	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793509&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219663	528824972							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728867	CNc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C27H24FN7O2/c1-30-19-4-5-20-21(14-19)24(32-33-26(20)36)13-17-2-6-23(28)22(12-17)27(37)35-10-8-34(9-11-35)25-7-3-18(15-29)16-31-25/h2-7,12,14,16,30H,8-11,13H2,1H3,(H,33,36)	XPHGBIKLPHFOAT-UHFFFAOYSA-N	793510	US20260055079, Example 16	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793510	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793510&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220225	528824973							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728868	CNc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C27H24FN7O2/c1-30-19-4-5-20-21(14-19)24(32-33-26(20)36)13-17-2-6-23(28)22(12-17)27(37)35-10-8-34(9-11-35)25-7-3-18(15-29)16-31-25/h2-7,12,14,16,30H,8-11,13H2,1H3,(H,33,36)	XPHGBIKLPHFOAT-UHFFFAOYSA-N	793510	US20260055079, Example 16	Poly [ADP-ribose] polymerase 2	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793510	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793510&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220225	528824973							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728869	C#CCN(C)c1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C30H26FN7O2/c1-3-10-36(2)22-6-7-23-24(17-22)27(34-35-29(23)39)16-20-4-8-26(31)25(15-20)30(40)38-13-11-37(12-14-38)28-9-5-21(18-32)19-33-28/h1,4-9,15,17,19H,10-14,16H2,2H3,(H,35,39)	XJPKZFDRZBAPDX-UHFFFAOYSA-N	793511	US20260055079, Example 17	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793511	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793511&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220100	528824974							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728870	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(N6CC(F)(F)C6)cc45)ccc3F)CC2)nc1	InChI=1S/C29H24F3N7O2/c30-24-5-1-18(11-23(24)28(41)38-9-7-37(8-10-38)26-6-2-19(14-33)15-34-26)12-25-22-13-20(39-16-29(31,32)17-39)3-4-21(22)27(40)36-35-25/h1-6,11,13,15H,7-10,12,16-17H2,(H,36,40)	TZYRCOBLKXCSRX-UHFFFAOYSA-N	793512	US20260055079, Example 18	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793512	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793512&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220347	528824975							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728871	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(N6CC(F)(F)C6)cc45)ccc3F)CC2)nc1	InChI=1S/C29H24F3N7O2/c30-24-5-1-18(11-23(24)28(41)38-9-7-37(8-10-38)26-6-2-19(14-33)15-34-26)12-25-22-13-20(39-16-29(31,32)17-39)3-4-21(22)27(40)36-35-25/h1-6,11,13,15H,7-10,12,16-17H2,(H,36,40)	TZYRCOBLKXCSRX-UHFFFAOYSA-N	793512	US20260055079, Example 18	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793512	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793512&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220347	528824975							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728872	CC#CCOc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C30H25FN6O3/c1-2-3-14-40-22-6-7-23-24(17-22)27(34-35-29(23)38)16-20-4-8-26(31)25(15-20)30(39)37-12-10-36(11-13-37)28-9-5-21(18-32)19-33-28/h4-9,15,17,19H,10-14,16H2,1H3,(H,35,38)	MKFAXVTVZSYBII-UHFFFAOYSA-N	793513	US20260055079, Example 19	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793513	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793513&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220323	528824976							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728873	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(NCC6CC6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H28FN7O2/c31-26-7-3-20(14-27-24-15-22(33-17-19-1-2-19)5-6-23(24)29(39)36-35-27)13-25(26)30(40)38-11-9-37(10-12-38)28-8-4-21(16-32)18-34-28/h3-8,13,15,18-19,33H,1-2,9-12,14,17H2,(H,36,39)	PVTYPFICFYQUDB-UHFFFAOYSA-N	793514	US20260055079, Example 20	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793514&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219692	528824977							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728874	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(NCC6CC6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H28FN7O2/c31-26-7-3-20(14-27-24-15-22(33-17-19-1-2-19)5-6-23(24)29(39)36-35-27)13-25(26)30(40)38-11-9-37(10-12-38)28-8-4-21(16-32)18-34-28/h3-8,13,15,18-19,33H,1-2,9-12,14,17H2,(H,36,39)	PVTYPFICFYQUDB-UHFFFAOYSA-N	793514	US20260055079, Example 20	Poly [ADP-ribose] polymerase 2	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793514&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219692	528824977							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728875	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C27H21F3N6O3/c28-22-5-1-16(12-23-20-13-18(39-27(29)30)3-4-19(20)25(37)34-33-23)11-21(22)26(38)36-9-7-35(8-10-36)24-6-2-17(14-31)15-32-24/h1-6,11,13,15,27H,7-10,12H2,(H,34,37)	VBXQVKUJFJRGFN-UHFFFAOYSA-N	793515	US20260055079, Example 21	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793515	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793515&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219657	528824978							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728876	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(NCC(F)(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C28H23F4N7O2/c29-23-5-1-17(12-24-21-13-19(35-16-28(30,31)32)3-4-20(21)26(40)37-36-24)11-22(23)27(41)39-9-7-38(8-10-39)25-6-2-18(14-33)15-34-25/h1-6,11,13,15,35H,7-10,12,16H2,(H,37,40)	OCIDFSBXKCWRES-UHFFFAOYSA-N	793516	US20260055079, Example 22	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793516&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219492	528824979							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728877	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(N6CC7(CC(O)C7)C6)cc45)ccc3F)CC2)nc1	InChI=1S/C32H30FN7O3/c33-27-5-1-20(11-26(27)31(43)39-9-7-38(8-10-39)29-6-2-21(16-34)17-35-29)12-28-25-13-22(3-4-24(25)30(42)37-36-28)40-18-32(19-40)14-23(41)15-32/h1-6,11,13,17,23,41H,7-10,12,14-15,18-19H2,(H,37,42)	OKKOKGOBLWLQFR-UHFFFAOYSA-N	793517	US20260055079, Example 23	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793517	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793517&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219546	528824980							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728878	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(N6CC7(CC(O)C7)C6)cc45)ccc3F)CC2)nc1	InChI=1S/C32H30FN7O3/c33-27-5-1-20(11-26(27)31(43)39-9-7-38(8-10-39)29-6-2-21(16-34)17-35-29)12-28-25-13-22(3-4-24(25)30(42)37-36-28)40-18-32(19-40)14-23(41)15-32/h1-6,11,13,17,23,41H,7-10,12,14-15,18-19H2,(H,37,42)	OKKOKGOBLWLQFR-UHFFFAOYSA-N	793517	US20260055079, Example 23	Poly [ADP-ribose] polymerase 2	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793517	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793517&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219546	528824980							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728879	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(C#CC(F)(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C29H20F4N6O2/c30-24-5-2-19(15-25-22-13-18(7-8-29(31,32)33)1-4-21(22)27(40)37-36-25)14-23(24)28(41)39-11-9-38(10-12-39)26-6-3-20(16-34)17-35-26/h1-6,13-14,17H,9-12,15H2,(H,37,40)	FQBZGOZQSULASL-UHFFFAOYSA-N	793518	US20260055079, Example 24	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793518&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219890	528824981							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728880	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(C#CC(F)(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C29H20F4N6O2/c30-24-5-2-19(15-25-22-13-18(7-8-29(31,32)33)1-4-21(22)27(40)37-36-25)14-23(24)28(41)39-11-9-38(10-12-39)26-6-3-20(16-34)17-35-26/h1-6,13-14,17H,9-12,15H2,(H,37,40)	FQBZGOZQSULASL-UHFFFAOYSA-N	793518	US20260055079, Example 24	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793518&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219890	528824981							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728881	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(CCC(F)(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C29H24F4N6O2/c30-24-5-2-19(15-25-22-13-18(7-8-29(31,32)33)1-4-21(22)27(40)37-36-25)14-23(24)28(41)39-11-9-38(10-12-39)26-6-3-20(16-34)17-35-26/h1-6,13-14,17H,7-12,15H2,(H,37,40)	GCHQBCIDGDTGTB-UHFFFAOYSA-N	793519	US20260055079, Example 25	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793519	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793519&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220335	528824982							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728882	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(CCC(F)(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C29H24F4N6O2/c30-24-5-2-19(15-25-22-13-18(7-8-29(31,32)33)1-4-21(22)27(40)37-36-25)14-23(24)28(41)39-11-9-38(10-12-39)26-6-3-20(16-34)17-35-26/h1-6,13-14,17H,7-12,15H2,(H,37,40)	GCHQBCIDGDTGTB-UHFFFAOYSA-N	793519	US20260055079, Example 25	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793519	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793519&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220335	528824982							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728883	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(N6CC(F)(F)C6)cc45)ccc3F)CC2)nc1	InChI=1S/C29H24F3N7O2/c30-24-5-1-18(11-23(24)28(41)38-9-7-37(8-10-38)26-6-2-19(14-33)15-34-26)12-25-22-13-20(39-16-29(31,32)17-39)3-4-21(22)27(40)36-35-25/h1-6,11,13,15H,7-10,12,16-17H2,(H,36,40)	TZYRCOBLKXCSRX-UHFFFAOYSA-N	793520	US20260055079, Example 26	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793520&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220347	528824983							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728884	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(N6CC(F)(F)C6)cc45)ccc3F)CC2)nc1	InChI=1S/C29H24F3N7O2/c30-24-5-1-18(11-23(24)28(41)38-9-7-37(8-10-38)26-6-2-19(14-33)15-34-26)12-25-22-13-20(39-16-29(31,32)17-39)3-4-21(22)27(40)36-35-25/h1-6,11,13,15H,7-10,12,16-17H2,(H,36,40)	TZYRCOBLKXCSRX-UHFFFAOYSA-N	793520	US20260055079, Example 26	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793520&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220347	528824983							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728885	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(/C=C/C(F)(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C29H22F4N6O2/c30-24-5-2-19(15-25-22-13-18(7-8-29(31,32)33)1-4-21(22)27(40)37-36-25)14-23(24)28(41)39-11-9-38(10-12-39)26-6-3-20(16-34)17-35-26/h1-8,13-14,17H,9-12,15H2,(H,37,40)	CGBMHKQWXUXKNW-UHFFFAOYSA-N	793521	US20260055079, Example 27	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793521	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793521&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220314	528824984							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728886	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(/C=C/C(F)(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C29H22F4N6O2/c30-24-5-2-19(15-25-22-13-18(7-8-29(31,32)33)1-4-21(22)27(40)37-36-25)14-23(24)28(41)39-11-9-38(10-12-39)26-6-3-20(16-34)17-35-26/h1-8,13-14,17H,9-12,15H2,(H,37,40)	CGBMHKQWXUXKNW-UHFFFAOYSA-N	793521	US20260055079, Example 27	Poly [ADP-ribose] polymerase 2	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793521	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793521&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220314	528824984							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728887	CN(C)c1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C28H26FN7O2/c1-34(2)20-5-6-21-22(15-20)25(32-33-27(21)37)14-18-3-7-24(29)23(13-18)28(38)36-11-9-35(10-12-36)26-8-4-19(16-30)17-31-26/h3-8,13,15,17H,9-12,14H2,1-2H3,(H,33,37)	JMOGIZWAZLFYCN-UHFFFAOYSA-N	793522	US20260055079, Example 28	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793522&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219884	528824985							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728888	CN(C)c1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C28H26FN7O2/c1-34(2)20-5-6-21-22(15-20)25(32-33-27(21)37)14-18-3-7-24(29)23(13-18)28(38)36-11-9-35(10-12-36)26-8-4-19(16-30)17-31-26/h3-8,13,15,17H,9-12,14H2,1-2H3,(H,33,37)	JMOGIZWAZLFYCN-UHFFFAOYSA-N	793522	US20260055079, Example 28	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793522&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219884	528824985							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728889	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(NC6CCC6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H28FN7O2/c31-26-8-4-19(15-27-24-16-22(34-21-2-1-3-21)6-7-23(24)29(39)36-35-27)14-25(26)30(40)38-12-10-37(11-13-38)28-9-5-20(17-32)18-33-28/h4-9,14,16,18,21,34H,1-3,10-13,15H2,(H,36,39)	JKDPZCQQDGEFQD-UHFFFAOYSA-N	793523	US20260055079, Example 29	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793523	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793523&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219793	528824986							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728890	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC(F)(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C27H20F4N6O3/c28-22-5-1-16(12-23-20-13-18(40-27(29,30)31)3-4-19(20)25(38)35-34-23)11-21(22)26(39)37-9-7-36(8-10-37)24-6-2-17(14-32)15-33-24/h1-6,11,13,15H,7-10,12H2,(H,35,38)	ICSDDZXBIZJFJF-UHFFFAOYSA-N	793524	US20260055079, Example 30	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793524&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220310	528824987							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728891	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC(F)(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C27H20F4N6O3/c28-22-5-1-16(12-23-20-13-18(40-27(29,30)31)3-4-19(20)25(38)35-34-23)11-21(22)26(39)37-9-7-36(8-10-37)24-6-2-17(14-32)15-33-24/h1-6,11,13,15H,7-10,12H2,(H,35,38)	ICSDDZXBIZJFJF-UHFFFAOYSA-N	793524	US20260055079, Example 30	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793524&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220310	528824987							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728892	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(N6CC7(CCC7)C6)cc45)ccc3F)CC2)nc1	InChI=1S/C32H30FN7O2/c33-27-6-2-21(14-26(27)31(42)39-12-10-38(11-13-39)29-7-3-22(17-34)18-35-29)15-28-25-16-23(4-5-24(25)30(41)37-36-28)40-19-32(20-40)8-1-9-32/h2-7,14,16,18H,1,8-13,15,19-20H2,(H,37,41)	GRQUTBVMLFLYBY-UHFFFAOYSA-N	793525	US20260055079, Example 31	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793525&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220003	528824988							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728893	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(N6CC7(CCC7)C6)cc45)ccc3F)CC2)nc1	InChI=1S/C32H30FN7O2/c33-27-6-2-21(14-26(27)31(42)39-12-10-38(11-13-39)29-7-3-22(17-34)18-35-29)15-28-25-16-23(4-5-24(25)30(41)37-36-28)40-19-32(20-40)8-1-9-32/h2-7,14,16,18H,1,8-13,15,19-20H2,(H,37,41)	GRQUTBVMLFLYBY-UHFFFAOYSA-N	793525	US20260055079, Example 31	Poly [ADP-ribose] polymerase 2	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793525&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220003	528824988							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728894	C/C(=C\C(F)(F)F)c1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C30H24F4N6O2/c1-18(15-30(32,33)34)21-4-5-22-23(14-21)26(37-38-28(22)41)13-19-2-6-25(31)24(12-19)29(42)40-10-8-39(9-11-40)27-7-3-20(16-35)17-36-27/h2-7,12,14-15,17H,8-11,13H2,1H3,(H,38,41)	LCHMLHCZFBFTOE-UHFFFAOYSA-N	793526	US20260055079, Example 32	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793526	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793526&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219572	528824989							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728895	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(NCCC(F)(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C29H25F4N7O2/c30-24-5-1-18(13-23(24)28(42)40-11-9-39(10-12-40)26-6-2-19(16-34)17-36-26)14-25-22-15-20(35-8-7-29(31,32)33)3-4-21(22)27(41)38-37-25/h1-6,13,15,17,35H,7-12,14H2,(H,38,41)	XVTACNYCSBFTPG-UHFFFAOYSA-N	793527	US20260055079, Example 33	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793527	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793527&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220016	528824990							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728896	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(N6CC(C(F)(F)F)C6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H25F4N7O2/c31-25-5-1-18(11-24(25)29(43)40-9-7-39(8-10-40)27-6-2-19(14-35)15-36-27)12-26-23-13-21(3-4-22(23)28(42)38-37-26)41-16-20(17-41)30(32,33)34/h1-6,11,13,15,20H,7-10,12,16-17H2,(H,38,42)	VIASXFQUKGWAQM-UHFFFAOYSA-N	793528	US20260055079, Example 34	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793528	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793528&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219579	528824991							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728897	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(N6CC(C(F)(F)F)C6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H25F4N7O2/c31-25-5-1-18(11-24(25)29(43)40-9-7-39(8-10-40)27-6-2-19(14-35)15-36-27)12-26-23-13-21(3-4-22(23)28(42)38-37-26)41-16-20(17-41)30(32,33)34/h1-6,11,13,15,20H,7-10,12,16-17H2,(H,38,42)	VIASXFQUKGWAQM-UHFFFAOYSA-N	793528	US20260055079, Example 34	Poly [ADP-ribose] polymerase 2	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793528	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793528&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219579	528824991							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728898	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(N6CC7(C6)CC(F)(F)C7)cc45)ccc3F)CC2)nc1	InChI=1S/C32H28F3N7O2/c33-26-5-1-20(11-25(26)30(44)41-9-7-40(8-10-41)28-6-2-21(14-36)15-37-28)12-27-24-13-22(3-4-23(24)29(43)39-38-27)42-18-31(19-42)16-32(34,35)17-31/h1-6,11,13,15H,7-10,12,16-19H2,(H,39,43)	ZHMKSGNRDICGED-UHFFFAOYSA-N	793529	US20260055079, Example 35	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793529	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793529&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220327	528824992							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728899	CC(F)(F)c1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C28H23F3N6O2/c1-28(30,31)19-4-5-20-21(14-19)24(34-35-26(20)38)13-17-2-6-23(29)22(12-17)27(39)37-10-8-36(9-11-37)25-7-3-18(15-32)16-33-25/h2-7,12,14,16H,8-11,13H2,1H3,(H,35,38)	ZXTLRNZNJLAFLZ-UHFFFAOYSA-N	793530	US20260055079, Example 36	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793530	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793530&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219686	528824993							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728900	CC(F)(F)c1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C28H23F3N6O2/c1-28(30,31)19-4-5-20-21(14-19)24(34-35-26(20)38)13-17-2-6-23(29)22(12-17)27(39)37-10-8-36(9-11-37)25-7-3-18(15-32)16-33-25/h2-7,12,14,16H,8-11,13H2,1H3,(H,35,38)	ZXTLRNZNJLAFLZ-UHFFFAOYSA-N	793530	US20260055079, Example 36	Poly [ADP-ribose] polymerase 2	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793530	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793530&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219686	528824993							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728901	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(C#CC6CC6)cc45)ccc3F)CC2)nc1	InChI=1S/C31H25FN6O2/c32-27-9-6-22(17-28-25-15-21(4-3-20-1-2-20)5-8-24(25)30(39)36-35-28)16-26(27)31(40)38-13-11-37(12-14-38)29-10-7-23(18-33)19-34-29/h5-10,15-16,19-20H,1-2,11-14,17H2,(H,36,39)	UZMGQUQJVPLJIC-UHFFFAOYSA-N	793531	US20260055079, Example 37	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793531	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793531&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220009	528824994							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728902	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(C#CC6CC6)cc45)ccc3F)CC2)nc1	InChI=1S/C31H25FN6O2/c32-27-9-6-22(17-28-25-15-21(4-3-20-1-2-20)5-8-24(25)30(39)36-35-28)16-26(27)31(40)38-13-11-37(12-14-38)29-10-7-23(18-33)19-34-29/h5-10,15-16,19-20H,1-2,11-14,17H2,(H,36,39)	UZMGQUQJVPLJIC-UHFFFAOYSA-N	793531	US20260055079, Example 37	Poly [ADP-ribose] polymerase 2	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793531	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793531&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220009	528824994							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728903	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(Oc6ccccn6)cc45)ccc3F)CC2)nc1	InChI=1S/C31H24FN7O3/c32-26-8-4-20(15-25(26)31(41)39-13-11-38(12-14-39)28-9-5-21(18-33)19-35-28)16-27-24-17-22(42-29-3-1-2-10-34-29)6-7-23(24)30(40)37-36-27/h1-10,15,17,19H,11-14,16H2,(H,37,40)	IGXRNFRVCXNXDU-UHFFFAOYSA-N	793532	US20260055079, Example 38	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793532	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793532&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220275	528824995							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728904	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(Oc6ccc7ccccc7c6)cc45)ccc3F)CC2)nc1	InChI=1S/C36H27FN6O3/c37-32-11-5-23(17-31(32)36(45)43-15-13-42(14-16-43)34-12-6-24(21-38)22-39-34)18-33-30-20-28(9-10-29(30)35(44)41-40-33)46-27-8-7-25-3-1-2-4-26(25)19-27/h1-12,17,19-20,22H,13-16,18H2,(H,41,44)	WCQIPYIIRWWSDG-UHFFFAOYSA-N	793533	US20260055079, Example 39	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793533	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793533&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219778	528824996							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728905	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(C6CC6)cc45)ccc3F)CC2)nc1	InChI=1S/C29H25FN6O2/c30-25-7-1-18(14-26-23-15-21(20-3-4-20)5-6-22(23)28(37)34-33-26)13-24(25)29(38)36-11-9-35(10-12-36)27-8-2-19(16-31)17-32-27/h1-2,5-8,13,15,17,20H,3-4,9-12,14H2,(H,34,37)	WTGPEUMJMTWUBJ-UHFFFAOYSA-N	793534	US20260055079, Example 40	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793534	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793534&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220099	528824997							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728906	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(C6CC6)cc45)ccc3F)CC2)nc1	InChI=1S/C29H25FN6O2/c30-25-7-1-18(14-26-23-15-21(20-3-4-20)5-6-22(23)28(37)34-33-26)13-24(25)29(38)36-11-9-35(10-12-36)27-8-2-19(16-31)17-32-27/h1-2,5-8,13,15,17,20H,3-4,9-12,14H2,(H,34,37)	WTGPEUMJMTWUBJ-UHFFFAOYSA-N	793534	US20260055079, Example 40	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793534	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793534&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220099	528824997							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728907	CC(C)(C)Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C31H31FN6O2/c1-31(2,3)17-21-4-7-23-24(15-21)27(35-36-29(23)39)16-20-5-8-26(32)25(14-20)30(40)38-12-10-37(11-13-38)28-9-6-22(18-33)19-34-28/h4-9,14-15,19H,10-13,16-17H2,1-3H3,(H,36,39)	OBXIMILHRARFDP-UHFFFAOYSA-N	793535	US20260055079, Example 41	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793535	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793535&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219584	528824998							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728908	CC(C)(C)Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C31H31FN6O2/c1-31(2,3)17-21-4-7-23-24(15-21)27(35-36-29(23)39)16-20-5-8-26(32)25(14-20)30(40)38-12-10-37(11-13-38)28-9-6-22(18-33)19-34-28/h4-9,14-15,19H,10-13,16-17H2,1-3H3,(H,36,39)	OBXIMILHRARFDP-UHFFFAOYSA-N	793535	US20260055079, Example 41	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793535	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793535&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219584	528824998							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728909	CC(C)(C)C#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ncc(C(F)(F)F)cn5)CC4)c3)c2c1	InChI=1S/C31H28F4N6O2/c1-30(2,3)9-8-19-4-6-22-23(14-19)26(38-39-27(22)42)16-20-5-7-25(32)24(15-20)28(43)40-10-12-41(13-11-40)29-36-17-21(18-37-29)31(33,34)35/h4-7,14-15,17-18H,10-13,16H2,1-3H3,(H,39,42)	WLTUIZSIOJMHJC-UHFFFAOYSA-N	793536	US20260055079, Example 42	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793536	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793536&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219646	528824999							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728910	CCc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ncc(C(F)(F)F)cn5)CC4)c3)c2c1	InChI=1S/C27H24F4N6O2/c1-2-16-3-5-19-20(11-16)23(34-35-24(19)38)13-17-4-6-22(28)21(12-17)25(39)36-7-9-37(10-8-36)26-32-14-18(15-33-26)27(29,30)31/h3-6,11-12,14-15H,2,7-10,13H2,1H3,(H,35,38)	ZFRDPNJMUWGXKO-UHFFFAOYSA-N	793537	US20260055079, Example 43	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793537	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793537&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219779	528825000							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728911	CCc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ncc(C(F)(F)F)cn5)CC4)c3)c2c1	InChI=1S/C27H24F4N6O2/c1-2-16-3-5-19-20(11-16)23(34-35-24(19)38)13-17-4-6-22(28)21(12-17)25(39)36-7-9-37(10-8-36)26-32-14-18(15-33-26)27(29,30)31/h3-6,11-12,14-15H,2,7-10,13H2,1H3,(H,35,38)	ZFRDPNJMUWGXKO-UHFFFAOYSA-N	793537	US20260055079, Example 43	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793537	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793537&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219779	528825000							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728912	CC(C)Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ncc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C29H28FN7O2/c1-18(2)11-19-3-5-22-23(12-19)26(34-35-27(22)38)14-20-4-6-25(30)24(13-20)28(39)36-7-9-37(10-8-36)29-32-16-21(15-31)17-33-29/h3-6,12-13,16-18H,7-11,14H2,1-2H3,(H,35,38)	PNJPNRABXORLNT-UHFFFAOYSA-N	793538	US20260055079, Example 44	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793538	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793538&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			178422886	528825001							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728913	CC(C)Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ncc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C29H28FN7O2/c1-18(2)11-19-3-5-22-23(12-19)26(34-35-27(22)38)14-20-4-6-25(30)24(13-20)28(39)36-7-9-37(10-8-36)29-32-16-21(15-31)17-33-29/h3-6,12-13,16-18H,7-11,14H2,1-2H3,(H,35,38)	PNJPNRABXORLNT-UHFFFAOYSA-N	793538	US20260055079, Example 44	Poly [ADP-ribose] polymerase 2	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793538	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793538&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			178422886	528825001							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728914	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(C4CC4)cc23)ccc1F)N1CCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C28H24F4N6O2/c29-23-6-1-16(12-24-21-13-18(17-2-3-17)4-5-20(21)25(39)36-35-24)11-22(23)26(40)37-7-9-38(10-8-37)27-33-14-19(15-34-27)28(30,31)32/h1,4-6,11,13-15,17H,2-3,7-10,12H2,(H,36,39)	IEGXGEZGOAYXMT-UHFFFAOYSA-N	793539	US20260055079, Example 45	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793539	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793539&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219698	528825002							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728915	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(C4CC4)cc23)ccc1F)N1CCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C28H24F4N6O2/c29-23-6-1-16(12-24-21-13-18(17-2-3-17)4-5-20(21)25(39)36-35-24)11-22(23)26(40)37-7-9-38(10-8-37)27-33-14-19(15-34-27)28(30,31)32/h1,4-6,11,13-15,17H,2-3,7-10,12H2,(H,36,39)	IEGXGEZGOAYXMT-UHFFFAOYSA-N	793539	US20260055079, Example 45	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793539	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793539&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219698	528825002							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728916	CN(C)CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ncc(C(F)(F)F)cn5)CC4)c3)c2c1	InChI=1S/C30H27F4N7O2/c1-39(2)9-3-4-19-5-7-22-23(14-19)26(37-38-27(22)42)16-20-6-8-25(31)24(15-20)28(43)40-10-12-41(13-11-40)29-35-17-21(18-36-29)30(32,33)34/h5-8,14-15,17-18H,9-13,16H2,1-2H3,(H,38,42)	LNZDCDMYWFLCEW-UHFFFAOYSA-N	793540	US20260055079, Example 46	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793540	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793540&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219490	528825003							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728917	CN(C)CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ncc(C(F)(F)F)cn5)CC4)c3)c2c1	InChI=1S/C30H27F4N7O2/c1-39(2)9-3-4-19-5-7-22-23(14-19)26(37-38-27(22)42)16-20-6-8-25(31)24(15-20)28(43)40-10-12-41(13-11-40)29-35-17-21(18-36-29)30(32,33)34/h5-8,14-15,17-18H,9-13,16H2,1-2H3,(H,38,42)	LNZDCDMYWFLCEW-UHFFFAOYSA-N	793540	US20260055079, Example 46	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793540	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793540&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219490	528825003							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728918	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(C#CC4CC4)cc23)ccc1F)N1CCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C30H24F4N6O2/c31-25-8-6-20(15-26-23-13-19(4-3-18-1-2-18)5-7-22(23)27(41)38-37-26)14-24(25)28(42)39-9-11-40(12-10-39)29-35-16-21(17-36-29)30(32,33)34/h5-8,13-14,16-18H,1-2,9-12,15H2,(H,38,41)	CJYMFHQPDYMZKK-UHFFFAOYSA-N	793541	US20260055079, Example 47	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793541	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793541&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220400	528825004							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728919	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(C#CC4CC4)cc23)ccc1F)N1CCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C30H24F4N6O2/c31-25-8-6-20(15-26-23-13-19(4-3-18-1-2-18)5-7-22(23)27(41)38-37-26)14-24(25)28(42)39-9-11-40(12-10-39)29-35-16-21(17-36-29)30(32,33)34/h5-8,13-14,16-18H,1-2,9-12,15H2,(H,38,41)	CJYMFHQPDYMZKK-UHFFFAOYSA-N	793541	US20260055079, Example 47	Poly [ADP-ribose] polymerase 2	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793541	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793541&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220400	528825004							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728920	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ncc(C(F)(F)F)cn5)CC4)c3)c2c1	InChI=1S/C28H22F4N6O2/c1-2-3-17-4-6-20-21(12-17)24(35-36-25(20)39)14-18-5-7-23(29)22(13-18)26(40)37-8-10-38(11-9-37)27-33-15-19(16-34-27)28(30,31)32/h4-7,12-13,15-16H,8-11,14H2,1H3,(H,36,39)	OMXTXRBPBZLVEQ-UHFFFAOYSA-N	793542	US20260055079, Example 48	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793542	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793542&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220185	528825005							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728921	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ncc(C(F)(F)F)cn5)CC4)c3)c2c1	InChI=1S/C28H22F4N6O2/c1-2-3-17-4-6-20-21(12-17)24(35-36-25(20)39)14-18-5-7-23(29)22(13-18)26(40)37-8-10-38(11-9-37)27-33-15-19(16-34-27)28(30,31)32/h4-7,12-13,15-16H,8-11,14H2,1H3,(H,36,39)	OMXTXRBPBZLVEQ-UHFFFAOYSA-N	793542	US20260055079, Example 48	Poly [ADP-ribose] polymerase 2	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793542	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793542&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220185	528825005							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728922	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(C#CC(F)(F)F)cc23)ccc1F)N1CCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C28H19F7N6O2/c29-22-4-2-17(13-23-20-11-16(5-6-27(30,31)32)1-3-19(20)24(42)39-38-23)12-21(22)25(43)40-7-9-41(10-8-40)26-36-14-18(15-37-26)28(33,34)35/h1-4,11-12,14-15H,7-10,13H2,(H,39,42)	HTHLXNJJNPGIIH-UHFFFAOYSA-N	793543	US20260055079, Example 49	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793543	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793543&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220155	528825006							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728923	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(C#CC(F)(F)F)cc23)ccc1F)N1CCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C28H19F7N6O2/c29-22-4-2-17(13-23-20-11-16(5-6-27(30,31)32)1-3-19(20)24(42)39-38-23)12-21(22)25(43)40-7-9-41(10-8-40)26-36-14-18(15-37-26)28(33,34)35/h1-4,11-12,14-15H,7-10,13H2,(H,39,42)	HTHLXNJJNPGIIH-UHFFFAOYSA-N	793543	US20260055079, Example 49	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793543	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793543&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220155	528825006							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728924	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CC(F)(F)C6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H25F3N6O3/c31-25-5-1-18(11-24(25)29(41)39-9-7-38(8-10-39)27-6-2-19(16-34)17-35-27)12-26-23-13-20(42-21-14-30(32,33)15-21)3-4-22(23)28(40)37-36-26/h1-6,11,13,17,21H,7-10,12,14-15H2,(H,37,40)	IYIOGBDJQIBRLN-UHFFFAOYSA-N	793544	US20260055079, Example 51	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793544	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793544&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220029	528825007							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728925	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(S(=O)(=O)C6CCC6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H27FN6O4S/c31-26-8-4-19(14-25(26)30(39)37-12-10-36(11-13-37)28-9-5-20(17-32)18-33-28)15-27-24-16-22(42(40,41)21-2-1-3-21)6-7-23(24)29(38)35-34-27/h4-9,14,16,18,21H,1-3,10-13,15H2,(H,35,38)	BZVHVUXUCCETBK-UHFFFAOYSA-N	793545	US20260055079, Example 53	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793545	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793545&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219672	528825008							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728926	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(S(=O)(=O)C6CC(F)(F)C6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H25F3N6O4S/c31-25-5-1-18(11-24(25)29(41)39-9-7-38(8-10-39)27-6-2-19(16-34)17-35-27)12-26-23-13-20(3-4-22(23)28(40)37-36-26)44(42,43)21-14-30(32,33)15-21/h1-6,11,13,17,21H,7-10,12,14-15H2,(H,37,40)	BRWYFPZLXFBCPR-UHFFFAOYSA-N	793546	US20260055079, Example 54	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793546	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793546&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219753	528825009							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728927	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5cncc(C#N)n5)CC4)c3)c2c1	InChI=1S/C28H22FN7O2/c1-2-3-18-4-6-21-22(12-18)25(33-34-27(21)37)14-19-5-7-24(29)23(13-19)28(38)36-10-8-35(9-11-36)26-17-31-16-20(15-30)32-26/h4-7,12-13,16-17H,8-11,14H2,1H3,(H,34,37)	AWHNZBPLEZOXPW-UHFFFAOYSA-N	793547	US20260055079, Example 55	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793547	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793547&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219845	528825010							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728928	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5cc(C(=O)NC)ccn5)CC4)c3)c2c1	InChI=1S/C30H27FN6O3/c1-3-4-19-5-7-22-23(15-19)26(34-35-29(22)39)17-20-6-8-25(31)24(16-20)30(40)37-13-11-36(12-14-37)27-18-21(9-10-33-27)28(38)32-2/h5-10,15-16,18H,11-14,17H2,1-2H3,(H,32,38)(H,35,39)	GUQVSBSIVOHFJP-UHFFFAOYSA-N	793548	US20260055079, Example 56	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793548	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793548&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219711	528825011							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728929	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(C(=O)CCC(F)(F)F)CC4)c3)c2c1	InChI=1S/C27H24F4N4O3/c1-2-3-17-4-6-19-20(14-17)23(32-33-25(19)37)16-18-5-7-22(28)21(15-18)26(38)35-12-10-34(11-13-35)24(36)8-9-27(29,30)31/h4-7,14-15H,8-13,16H2,1H3,(H,33,37)	PEFNQVOIJPAHEA-UHFFFAOYSA-N	793549	US20260055079, Example 57	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793549	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793549&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220205	528825012							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728930	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(C(=O)CC#N)CC4)c3)c2c1	InChI=1S/C26H22FN5O3/c1-2-3-17-4-6-19-20(14-17)23(29-30-25(19)34)16-18-5-7-22(27)21(15-18)26(35)32-12-10-31(11-13-32)24(33)8-9-28/h4-7,14-15H,8,10-13,16H2,1H3,(H,30,34)	QBPZANPCGSWDKW-UHFFFAOYSA-N	793550	US20260055079, Example 58	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793550	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793550&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219690	528825013							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728931	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCn5c(nnc5-c5ccccc5CC)C4)c3)c2c1	InChI=1S/C32H27FN6O2/c1-3-7-20-10-12-24-25(16-20)28(34-37-31(24)40)18-21-11-13-27(33)26(17-21)32(41)38-14-15-39-29(19-38)35-36-30(39)23-9-6-5-8-22(23)4-2/h5-6,8-13,16-17H,4,14-15,18-19H2,1-2H3,(H,37,40)	AQRQHXIYGNXKQC-UHFFFAOYSA-N	793551	US20260055079, Example 59	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793551	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793551&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219578	528825014							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728932	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CC5(C4)CN(c4ccc(C#N)cn4)C5)c3)c2c1	InChI=1S/C30H23FN6O2/c1-2-3-19-4-7-22-23(10-19)26(34-35-28(22)38)12-20-5-8-25(31)24(11-20)29(39)37-17-30(18-37)15-36(16-30)27-9-6-21(13-32)14-33-27/h4-11,14H,12,15-18H2,1H3,(H,35,38)	IBMFXNKLCGZRFC-UHFFFAOYSA-N	793552	US20260055079, Example 60	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793552	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793552&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220122	528825015							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728933	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4C)c3)c2c1	InChI=1S/C30H25FN6O2/c1-3-4-20-5-8-23-24(13-20)27(34-35-29(23)38)15-21-6-9-26(31)25(14-21)30(39)37-12-11-36(18-19(37)2)28-10-7-22(16-32)17-33-28/h5-10,13-14,17,19H,11-12,15,18H2,1-2H3,(H,35,38)	NDAPBVFELLFMAN-UHFFFAOYSA-N	793553	US20260055079, Example 61	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793553	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793553&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220183	528825016							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728934	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4C)c3)c2c1	InChI=1S/C30H25FN6O2/c1-3-4-20-5-8-23-24(13-20)27(34-35-29(23)38)15-21-6-9-26(31)25(14-21)30(39)37-12-11-36(18-19(37)2)28-10-7-22(16-32)17-33-28/h5-10,13-14,17,19H,11-12,15,18H2,1-2H3,(H,35,38)	NDAPBVFELLFMAN-UHFFFAOYSA-N	793553	US20260055079, Example 61	Poly [ADP-ribose] polymerase 2	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793553	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793553&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220183	528825016							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728935	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4C5CCC4CN(c4ccc(C#N)cn4)C5)c3)c2c1	InChI=1S/C31H25FN6O2/c1-2-3-19-4-9-24-25(12-19)28(35-36-30(24)39)14-20-5-10-27(32)26(13-20)31(40)38-22-7-8-23(38)18-37(17-22)29-11-6-21(15-33)16-34-29/h4-6,9-13,16,22-23H,7-8,14,17-18H2,1H3,(H,36,39)	SSHDMBGTGCNWGV-UHFFFAOYSA-N	793554	US20260055079, Example 62	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793554	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793554&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219755	528825017							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728936	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4C5CCC4CN(c4ccc(C#N)cn4)C5)c3)c2c1	InChI=1S/C31H25FN6O2/c1-2-3-19-4-9-24-25(12-19)28(35-36-30(24)39)14-20-5-10-27(32)26(13-20)31(40)38-22-7-8-23(38)18-37(17-22)29-11-6-21(15-33)16-34-29/h4-6,9-13,16,22-23H,7-8,14,17-18H2,1H3,(H,36,39)	SSHDMBGTGCNWGV-UHFFFAOYSA-N	793554	US20260055079, Example 62	Poly [ADP-ribose] polymerase 2	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793554	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793554&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219755	528825017							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728937	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCn5c(nnc5C5CC5)C4)c3)c2c1	InChI=1S/C27H23FN6O2/c1-2-3-16-4-8-19-20(12-16)23(29-32-26(19)35)14-17-5-9-22(28)21(13-17)27(36)33-10-11-34-24(15-33)30-31-25(34)18-6-7-18/h4-5,8-9,12-13,18H,6-7,10-11,14-15H2,1H3,(H,32,35)	GIMAGKDKXZWOJX-UHFFFAOYSA-N	793555	US20260055079, Example 63	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793555	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793555&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219991	528825018							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728938	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CC5CCC(C4)N5c4ccc(C#N)cn4)c3)c2c1	InChI=1S/C31H25FN6O2/c1-2-3-19-4-9-24-25(12-19)28(35-36-30(24)39)14-20-5-10-27(32)26(13-20)31(40)37-17-22-7-8-23(18-37)38(22)29-11-6-21(15-33)16-34-29/h4-6,9-13,16,22-23H,7-8,14,17-18H2,1H3,(H,36,39)	OPJKYAUGHIQWMJ-UHFFFAOYSA-N	793556	US20260055079, Example 64	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793556	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793556&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219567	528825019							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728939	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCn5c(nnc5C(F)(F)F)C4)c3)c2c1	InChI=1S/C25H18F4N6O2/c1-2-3-14-4-6-16-17(10-14)20(30-32-22(16)36)12-15-5-7-19(26)18(11-15)23(37)34-8-9-35-21(13-34)31-33-24(35)25(27,28)29/h4-7,10-11H,8-9,12-13H2,1H3,(H,32,36)	PRNHZFSZYKPPML-UHFFFAOYSA-N	793557	US20260055079, Example 65	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793557	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793557&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220127	528825020							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728940	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCn5c(nnc5C(F)(F)F)C4)c3)c2c1	InChI=1S/C25H18F4N6O2/c1-2-3-14-4-6-16-17(10-14)20(30-32-22(16)36)12-15-5-7-19(26)18(11-15)23(37)34-8-9-35-21(13-34)31-33-24(35)25(27,28)29/h4-7,10-11H,8-9,12-13H2,1H3,(H,32,36)	PRNHZFSZYKPPML-UHFFFAOYSA-N	793557	US20260055079, Example 65	Poly [ADP-ribose] polymerase 1	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793557	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=232&target=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793557&enzyme=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search			169220127	528825020							1	MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW	9MJA,9MI8,4OQB,4OQA,4OPX,4DQY,8G0H,7S6M,7S6H,5A00,4ZZZ,4XHU,6XVW,5HA9,4PJT,2RCW,1WOK,1UK1,1UK0,6I8T,6I8M,7S81,7S68,6M3I,9DMC,9BPY,8FZ1,8FYZ,8FYY,6NTU,6NRJ,6NRI,6NRH,6NRG,6NRF,6BHV,5DS3,8U4W,2N8A,2RIQ,2JVN,2CR9,2CS2,2L31,2L30,3ODE,3ODC,7SCZ,7SCY,3ODA,3OD8,2DMJ,9UMC,9UMF	Poly [ADP-ribose] polymerase 1	PARP1_HUMAN	P09874	B1ANJ4 Q8IUZ9			N/A	A0A024R3T8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
728941	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCn5c(nnc5C(F)(F)F)C4)c3)c2c1	InChI=1S/C25H18F4N6O2/c1-2-3-14-4-6-16-17(10-14)20(30-32-22(16)36)12-15-5-7-19(26)18(11-15)23(37)34-8-9-35-21(13-34)31-33-24(35)25(27,28)29/h4-7,10-11H,8-9,12-13H2,1H3,(H,32,36)	PRNHZFSZYKPPML-UHFFFAOYSA-N	793557	US20260055079, Example 65	Poly [ADP-ribose] polymerase 2	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793557	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793557&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220127	528825020							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728942	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4C[C@H]5C[C@@H]4CN5c4ccc(C#N)cn4)c3)c2c1	InChI=1S/C30H23FN6O2/c1-2-3-18-4-7-23-24(10-18)27(34-35-29(23)38)12-19-5-8-26(31)25(11-19)30(39)37-17-21-13-22(37)16-36(21)28-9-6-20(14-32)15-33-28/h4-11,15,21-22H,12-13,16-17H2,1H3,(H,35,38)	FIMZNRMHKOBNCM-UHFFFAOYSA-N	793558	US20260055079, Example 66	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793558	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793558&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219749	528825021							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728943	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCC(F)(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C30H23F2N5O2/c1-2-3-19-4-7-22-23(14-19)26(35-36-28(22)38)16-20-5-8-25(31)24(15-20)29(39)37-12-10-30(32,11-13-37)27-9-6-21(17-33)18-34-27/h4-9,14-15,18H,10-13,16H2,1H3,(H,36,38)	PDLCVWDLPWFKBL-UHFFFAOYSA-N	793559	US20260055079, Example 67	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793559	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793559&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220267	528825022							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728944	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4C[C@@H]5C[C@H]4CN5c4ccc(C#N)cn4)c3)c2c1	InChI=1S/C30H23FN6O2/c1-2-3-18-4-7-23-24(10-18)27(34-35-29(23)38)12-19-5-8-26(31)25(11-19)30(39)37-17-21-13-22(37)16-36(21)28-9-6-20(14-32)15-33-28/h4-11,15,21-22H,12-13,16-17H2,1H3,(H,35,38)	FIMZNRMHKOBNCM-UHFFFAOYSA-N	793560	US20260055079, Example 68	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793560	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793560&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220383	528825023							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728945	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CC(N(C)c5cc(C#N)ccn5)C4)c3)c2c1	InChI=1S/C29H23FN6O2/c1-3-4-18-5-7-22-23(11-18)26(33-34-28(22)37)13-19-6-8-25(30)24(12-19)29(38)36-16-21(17-36)35(2)27-14-20(15-31)9-10-32-27/h5-12,14,21H,13,16-17H2,1-2H3,(H,34,37)	WAOBSRFFQHOIPT-UHFFFAOYSA-N	793561	US20260055079, Example 69	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793561	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793561&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219504	528825024							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728946	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CC(N(C)c5ccc(C#N)cn5)C4)c3)c2c1	InChI=1S/C29H23FN6O2/c1-3-4-18-5-8-22-23(11-18)26(33-34-28(22)37)13-19-6-9-25(30)24(12-19)29(38)36-16-21(17-36)35(2)27-10-7-20(14-31)15-32-27/h5-12,15,21H,13,16-17H2,1-2H3,(H,34,37)	MYAKHRZYXIUXTC-UHFFFAOYSA-N	793562	US20260055079, Example 70	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793562	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793562&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219963	528825025							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728947	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)C(=O)C4(C)C)c3)c2c1	InChI=1S/C31H25FN6O3/c1-4-5-19-6-9-22-23(14-19)26(35-36-28(22)39)16-20-7-10-25(32)24(15-20)29(40)38-13-12-37(30(41)31(38,2)3)27-11-8-21(17-33)18-34-27/h6-11,14-15,18H,12-13,16H2,1-3H3,(H,36,39)	REHVOEQRJKEBOH-UHFFFAOYSA-N	793563	US20260055079, Example 71	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793563	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793563&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219925	528825026							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728948	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)C(C)C4)c3)c2c1	InChI=1S/C30H25FN6O2/c1-3-4-20-5-8-23-24(13-20)27(34-35-29(23)38)15-21-6-9-26(31)25(14-21)30(39)36-11-12-37(19(2)18-36)28-10-7-22(16-32)17-33-28/h5-10,13-14,17,19H,11-12,15,18H2,1-2H3,(H,35,38)	VXKWEXPOCXICGN-UHFFFAOYSA-N	793564	US20260055079, Example 72	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793564	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793564&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220102	528825027							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728949	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)C(C)C4)c3)c2c1	InChI=1S/C30H25FN6O2/c1-3-4-20-5-8-23-24(13-20)27(34-35-29(23)38)15-21-6-9-26(31)25(14-21)30(39)36-11-12-37(19(2)18-36)28-10-7-22(16-32)17-33-28/h5-10,13-14,17,19H,11-12,15,18H2,1-2H3,(H,35,38)	VXKWEXPOCXICGN-UHFFFAOYSA-N	793564	US20260055079, Example 72	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793564	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793564&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220102	528825027							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728950	[2H]C([2H])(c1ccc(F)c(C(=O)N2CCN(c3ccc(C#N)cn3)CC2)c1)c1n[nH]c(=O)c2ccc(C#CC)cc12	InChI=1S/C29H23FN6O2/c1-2-3-19-4-7-22-23(14-19)26(33-34-28(22)37)16-20-5-8-25(30)24(15-20)29(38)36-12-10-35(11-13-36)27-9-6-21(17-31)18-32-27/h4-9,14-15,18H,10-13,16H2,1H3,(H,34,37)/i16D2	DOQGBJFQXSVRPN-BPPAMHLBSA-N	793565	US20260055079, Example 73	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793565	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793565&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220369	528825028							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728951	CC#Cc1ccc2c(=O)[nH]nc(Cc3cc(F)c(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C29H22F2N6O2/c1-2-3-18-4-6-21-22(12-18)25(34-35-28(21)38)15-20-13-23(27(31)24(30)14-20)29(39)37-10-8-36(9-11-37)26-7-5-19(16-32)17-33-26/h4-7,12-14,17H,8-11,15H2,1H3,(H,35,38)	KQLQHFRHBYLUDF-UHFFFAOYSA-N	793566	US20260055079, Example 74	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793566	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793566&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219645	528825029							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728952	CC#Cc1ccc2c(=O)[nH]nc(Cc3cc(F)c(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C29H22F2N6O2/c1-2-3-18-4-6-21-22(12-18)25(34-35-28(21)38)15-20-13-23(27(31)24(30)14-20)29(39)37-10-8-36(9-11-37)26-7-5-19(16-32)17-33-26/h4-7,12-14,17H,8-11,15H2,1H3,(H,35,38)	KQLQHFRHBYLUDF-UHFFFAOYSA-N	793566	US20260055079, Example 74	Poly [ADP-ribose] polymerase 2	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793566	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793566&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219645	528825029							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728953	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc4c(c3)C(=O)N(CCN(CC)c3ccc(C#N)cn3)C4)c2c1	InChI=1S/C30H26N6O2/c1-3-5-20-7-10-24-26(14-20)27(33-34-29(24)37)16-21-6-9-23-19-36(30(38)25(23)15-21)13-12-35(4-2)28-11-8-22(17-31)18-32-28/h6-11,14-15,18H,4,12-13,16,19H2,1-2H3,(H,34,37)	BAQXILDAGZIBHU-UHFFFAOYSA-N	793567	US20260055079, Example 75	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793567	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793567&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219718	528825030							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728954	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C#N)c3)c2c1	InChI=1S/C19H12FN3O/c1-2-3-12-4-6-15-16(9-12)18(22-23-19(15)24)10-13-5-7-17(20)14(8-13)11-21/h4-9H,10H2,1H3,(H,23,24)	GGFXWUHLIHSUHW-UHFFFAOYSA-N	793568	US20260055079, Example 76	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793568	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793568&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219465	528825031							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728955	CC#Cc1ccc2c(=O)[nH]nc(Cc3cc(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c(F)cc3F)c2c1	InChI=1S/C29H22F2N6O2/c1-2-3-18-4-6-21-22(12-18)26(34-35-28(21)38)14-20-13-23(25(31)15-24(20)30)29(39)37-10-8-36(9-11-37)27-7-5-19(16-32)17-33-27/h4-7,12-13,15,17H,8-11,14H2,1H3,(H,35,38)	IBKFUYOBBDWNDP-UHFFFAOYSA-N	793569	US20260055079, Example 77	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793569	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793569&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220376	528825032							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728956	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(NCCN(CC)c4ccc(C#N)cn4)C(F)(F)F)c3)c2c1	InChI=1S/C30H26F4N6O/c1-3-5-19-6-9-22-23(14-19)26(38-39-29(22)41)16-20-7-10-25(31)24(15-20)28(30(32,33)34)36-12-13-40(4-2)27-11-8-21(17-35)18-37-27/h6-11,14-15,18,28,36H,4,12-13,16H2,1-2H3,(H,39,41)	RVFQJCKVOZYOTA-UHFFFAOYSA-N	793570	US20260055079, Example 78	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793570	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793570&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220356	528825033							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728957	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ncc(C)n5C)CC4)c3)c2c1	InChI=1S/C28H27FN6O2/c1-4-5-19-6-8-21-22(14-19)25(31-32-26(21)36)16-20-7-9-24(29)23(15-20)27(37)34-10-12-35(13-11-34)28-30-17-18(2)33(28)3/h6-9,14-15,17H,10-13,16H2,1-3H3,(H,32,36)	SVSDDWRLDAWRIK-UHFFFAOYSA-N	793571	US20260055079, Example 79	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793571	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793571&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220062	528825034							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728958	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC(F)(F)C4)c3)c2c1	InChI=1S/C30H23F3N6O2/c1-2-3-19-4-7-22-23(12-19)26(36-37-28(22)40)14-20-5-8-25(31)24(13-20)29(41)39-11-10-38(17-30(32,33)18-39)27-9-6-21(15-34)16-35-27/h4-9,12-13,16H,10-11,14,17-18H2,1H3,(H,37,40)	FEXCVVNYBBHBAV-UHFFFAOYSA-N	793572	US20260055079, Example 80	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793572	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793572&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219832	528825035							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728959	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1OC	InChI=1S/C30H25FN6O3/c1-3-4-21-7-8-22-27(28(21)40-2)25(34-35-29(22)38)16-19-5-9-24(31)23(15-19)30(39)37-13-11-36(12-14-37)26-10-6-20(17-32)18-33-26/h5-10,15,18H,11-14,16H2,1-2H3,(H,35,38)	PBCGFOFIYOSKQQ-UHFFFAOYSA-N	793573	(SP-PAR700076-NX-1)::US20260055079, Example 81	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793573	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793573&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220131	528825036							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728960	COc1cc2c(Cc3cccc(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)n[nH]c(=O)c2cc1F	InChI=1S/C27H23FN6O3/c1-37-24-14-20-21(13-22(24)28)26(35)32-31-23(20)12-17-3-2-4-19(11-17)27(36)34-9-7-33(8-10-34)25-6-5-18(15-29)16-30-25/h2-6,11,13-14,16H,7-10,12H2,1H3,(H,32,35)	QYNNQRPLYWTJSG-UHFFFAOYSA-N	793574	US20260055079, Example 82	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793574	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793574&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220111	528825037							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728961	COc1cc2c(Cc3cccc(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)n[nH]c(=O)c2cc1F	InChI=1S/C27H23FN6O3/c1-37-24-14-20-21(13-22(24)28)26(35)32-31-23(20)12-17-3-2-4-19(11-17)27(36)34-9-7-33(8-10-34)25-6-5-18(15-29)16-30-25/h2-6,11,13-14,16H,7-10,12H2,1H3,(H,32,35)	QYNNQRPLYWTJSG-UHFFFAOYSA-N	793574	US20260055079, Example 82	Poly [ADP-ribose] polymerase 1	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793574	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=232&target=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793574&enzyme=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search			169220111	528825037							1	MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW	9MJA,9MI8,4OQB,4OQA,4OPX,4DQY,8G0H,7S6M,7S6H,5A00,4ZZZ,4XHU,6XVW,5HA9,4PJT,2RCW,1WOK,1UK1,1UK0,6I8T,6I8M,7S81,7S68,6M3I,9DMC,9BPY,8FZ1,8FYZ,8FYY,6NTU,6NRJ,6NRI,6NRH,6NRG,6NRF,6BHV,5DS3,8U4W,2N8A,2RIQ,2JVN,2CR9,2CS2,2L31,2L30,3ODE,3ODC,7SCZ,7SCY,3ODA,3OD8,2DMJ,9UMC,9UMF	Poly [ADP-ribose] polymerase 1	PARP1_HUMAN	P09874	B1ANJ4 Q8IUZ9			N/A	A0A024R3T8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
728962	COc1cc2c(Cc3cccc(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)n[nH]c(=O)c2cc1F	InChI=1S/C27H23FN6O3/c1-37-24-14-20-21(13-22(24)28)26(35)32-31-23(20)12-17-3-2-4-19(11-17)27(36)34-9-7-33(8-10-34)25-6-5-18(15-29)16-30-25/h2-6,11,13-14,16H,7-10,12H2,1H3,(H,32,35)	QYNNQRPLYWTJSG-UHFFFAOYSA-N	793574	US20260055079, Example 82	Poly [ADP-ribose] polymerase 2	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793574	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793574&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220111	528825037							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728963	CC#Cc1cc2c(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)n[nH]c(=O)c2cc1C	InChI=1S/C30H25FN6O2/c1-3-4-22-16-23-24(13-19(22)2)29(38)35-34-27(23)15-20-5-7-26(31)25(14-20)30(39)37-11-9-36(10-12-37)28-8-6-21(17-32)18-33-28/h5-8,13-14,16,18H,9-12,15H2,1-2H3,(H,35,38)	JJMGHUZRMYOOKH-UHFFFAOYSA-N	793575	US20260055079, Example 83	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793575	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793575&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219882	528825038							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728964	CC#Cc1cc(C(F)(F)F)c2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C30H22F4N6O2/c1-2-3-18-13-22-25(37-38-28(41)27(22)23(14-18)30(32,33)34)15-19-4-6-24(31)21(12-19)29(42)40-10-8-39(9-11-40)26-7-5-20(16-35)17-36-26/h4-7,12-14,17H,8-11,15H2,1H3,(H,38,41)	PXRWAYRHLCJGHV-UHFFFAOYSA-N	793576	US20260055079, Example 84	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793576	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793576&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219548	528825039							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728965	CC#Cc1cc(C(F)(F)F)c2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C30H22F4N6O2/c1-2-3-18-13-22-25(37-38-28(41)27(22)23(14-18)30(32,33)34)15-19-4-6-24(31)21(12-19)29(42)40-10-8-39(9-11-40)26-7-5-20(16-35)17-36-26/h4-7,12-14,17H,8-11,15H2,1H3,(H,38,41)	PXRWAYRHLCJGHV-UHFFFAOYSA-N	793576	US20260055079, Example 84	Poly [ADP-ribose] polymerase 1	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793576	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=232&target=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793576&enzyme=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search			169219548	528825039							1	MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW	9MJA,9MI8,4OQB,4OQA,4OPX,4DQY,8G0H,7S6M,7S6H,5A00,4ZZZ,4XHU,6XVW,5HA9,4PJT,2RCW,1WOK,1UK1,1UK0,6I8T,6I8M,7S81,7S68,6M3I,9DMC,9BPY,8FZ1,8FYZ,8FYY,6NTU,6NRJ,6NRI,6NRH,6NRG,6NRF,6BHV,5DS3,8U4W,2N8A,2RIQ,2JVN,2CR9,2CS2,2L31,2L30,3ODE,3ODC,7SCZ,7SCY,3ODA,3OD8,2DMJ,9UMC,9UMF	Poly [ADP-ribose] polymerase 1	PARP1_HUMAN	P09874	B1ANJ4 Q8IUZ9			N/A	A0A024R3T8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
728966	CC#Cc1cc(C(F)(F)F)c2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C30H22F4N6O2/c1-2-3-18-13-22-25(37-38-28(41)27(22)23(14-18)30(32,33)34)15-19-4-6-24(31)21(12-19)29(42)40-10-8-39(9-11-40)26-7-5-20(16-35)17-36-26/h4-7,12-14,17H,8-11,15H2,1H3,(H,38,41)	PXRWAYRHLCJGHV-UHFFFAOYSA-N	793576	US20260055079, Example 84	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793576	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793576&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219548	528825039							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728967	CC#Cc1cc(Cl)c2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C29H22ClFN6O2/c1-2-3-18-13-22-25(34-35-28(38)27(22)23(30)14-18)15-19-4-6-24(31)21(12-19)29(39)37-10-8-36(9-11-37)26-7-5-20(16-32)17-33-26/h4-7,12-14,17H,8-11,15H2,1H3,(H,35,38)	YBJFFXQOBIITSP-UHFFFAOYSA-N	793577	US20260055079, Example 85	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793577	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793577&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220147	528825040							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728968	CC#Cc1cc(Cl)c2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C29H22ClFN6O2/c1-2-3-18-13-22-25(34-35-28(38)27(22)23(30)14-18)15-19-4-6-24(31)21(12-19)29(39)37-10-8-36(9-11-37)26-7-5-20(16-32)17-33-26/h4-7,12-14,17H,8-11,15H2,1H3,(H,35,38)	YBJFFXQOBIITSP-UHFFFAOYSA-N	793577	US20260055079, Example 85	Poly [ADP-ribose] polymerase 2	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793577	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793577&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220147	528825040							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728969	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1C	InChI=1S/C30H25FN6O2/c1-3-4-22-7-8-23-28(19(22)2)26(34-35-29(23)38)16-20-5-9-25(31)24(15-20)30(39)37-13-11-36(12-14-37)27-10-6-21(17-32)18-33-27/h5-10,15,18H,11-14,16H2,1-2H3,(H,35,38)	VEUCPPXTEZSICN-UHFFFAOYSA-N	793578	US20260055079, Example 86	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793578	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793578&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220431	528825041							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728970	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1C	InChI=1S/C30H25FN6O2/c1-3-4-22-7-8-23-28(19(22)2)26(34-35-29(23)38)16-20-5-9-25(31)24(15-20)30(39)37-13-11-36(12-14-37)27-10-6-21(17-32)18-33-27/h5-10,15,18H,11-14,16H2,1-2H3,(H,35,38)	VEUCPPXTEZSICN-UHFFFAOYSA-N	793578	US20260055079, Example 86	Poly [ADP-ribose] polymerase 1	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793578	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=232&target=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793578&enzyme=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search			169220431	528825041							1	MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW	9MJA,9MI8,4OQB,4OQA,4OPX,4DQY,8G0H,7S6M,7S6H,5A00,4ZZZ,4XHU,6XVW,5HA9,4PJT,2RCW,1WOK,1UK1,1UK0,6I8T,6I8M,7S81,7S68,6M3I,9DMC,9BPY,8FZ1,8FYZ,8FYY,6NTU,6NRJ,6NRI,6NRH,6NRG,6NRF,6BHV,5DS3,8U4W,2N8A,2RIQ,2JVN,2CR9,2CS2,2L31,2L30,3ODE,3ODC,7SCZ,7SCY,3ODA,3OD8,2DMJ,9UMC,9UMF	Poly [ADP-ribose] polymerase 1	PARP1_HUMAN	P09874	B1ANJ4 Q8IUZ9			N/A	A0A024R3T8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
728971	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1C	InChI=1S/C30H25FN6O2/c1-3-4-22-7-8-23-28(19(22)2)26(34-35-29(23)38)16-20-5-9-25(31)24(15-20)30(39)37-13-11-36(12-14-37)27-10-6-21(17-32)18-33-27/h5-10,15,18H,11-14,16H2,1-2H3,(H,35,38)	VEUCPPXTEZSICN-UHFFFAOYSA-N	793578	US20260055079, Example 86	Poly [ADP-ribose] polymerase 2	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793578	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793578&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220431	528825041							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728972	N#Cc1ccc(N2CCN(C(=O)c3cccc(Cc4n[nH]c(=O)c5c(F)c(F)ccc45)c3)CC2)nc1	InChI=1S/C26H20F2N6O2/c27-20-6-5-19-21(31-32-25(35)23(19)24(20)28)13-16-2-1-3-18(12-16)26(36)34-10-8-33(9-11-34)22-7-4-17(14-29)15-30-22/h1-7,12,15H,8-11,13H2,(H,32,35)	PHSVUMZVUPAWCV-UHFFFAOYSA-N	793579	US20260055079, Example 87	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793579	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793579&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219590	528825042							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728973	N#Cc1ccc(N2CCN(C(=O)c3cccc(Cc4n[nH]c(=O)c5c(F)c(F)ccc45)c3)CC2)nc1	InChI=1S/C26H20F2N6O2/c27-20-6-5-19-21(31-32-25(35)23(19)24(20)28)13-16-2-1-3-18(12-16)26(36)34-10-8-33(9-11-34)22-7-4-17(14-29)15-30-22/h1-7,12,15H,8-11,13H2,(H,32,35)	PHSVUMZVUPAWCV-UHFFFAOYSA-N	793579	US20260055079, Example 87	Poly [ADP-ribose] polymerase 1	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793579	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=232&target=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793579&enzyme=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search			169219590	528825042							1	MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW	9MJA,9MI8,4OQB,4OQA,4OPX,4DQY,8G0H,7S6M,7S6H,5A00,4ZZZ,4XHU,6XVW,5HA9,4PJT,2RCW,1WOK,1UK1,1UK0,6I8T,6I8M,7S81,7S68,6M3I,9DMC,9BPY,8FZ1,8FYZ,8FYY,6NTU,6NRJ,6NRI,6NRH,6NRG,6NRF,6BHV,5DS3,8U4W,2N8A,2RIQ,2JVN,2CR9,2CS2,2L31,2L30,3ODE,3ODC,7SCZ,7SCY,3ODA,3OD8,2DMJ,9UMC,9UMF	Poly [ADP-ribose] polymerase 1	PARP1_HUMAN	P09874	B1ANJ4 Q8IUZ9			N/A	A0A024R3T8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
728974	N#Cc1ccc(N2CCN(C(=O)c3cccc(Cc4n[nH]c(=O)c5c(F)c(F)ccc45)c3)CC2)nc1	InChI=1S/C26H20F2N6O2/c27-20-6-5-19-21(31-32-25(35)23(19)24(20)28)13-16-2-1-3-18(12-16)26(36)34-10-8-33(9-11-34)22-7-4-17(14-29)15-30-22/h1-7,12,15H,8-11,13H2,(H,32,35)	PHSVUMZVUPAWCV-UHFFFAOYSA-N	793579	US20260055079, Example 87	Poly [ADP-ribose] polymerase 2	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793579	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793579&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219590	528825042							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728975	N#Cc1ccc(N2CCN(C(=O)c3cccc(Cc4n[nH]c(=O)c5c(F)cccc45)c3)CC2)nc1	InChI=1S/C26H21FN6O2/c27-21-6-2-5-20-22(30-31-25(34)24(20)21)14-17-3-1-4-19(13-17)26(35)33-11-9-32(10-12-33)23-8-7-18(15-28)16-29-23/h1-8,13,16H,9-12,14H2,(H,31,34)	LNHWMFZNYVUDTL-UHFFFAOYSA-N	793580	US20260055079, Example 88	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793580	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793580&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219627	528825043							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728976	COc1c(Oc2ccccc2)ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c12	InChI=1S/C33H27FN6O4/c1-43-31-28(44-23-5-3-2-4-6-23)11-9-24-30(31)27(37-38-32(24)41)18-21-7-10-26(34)25(17-21)33(42)40-15-13-39(14-16-40)29-12-8-22(19-35)20-36-29/h2-12,17,20H,13-16,18H2,1H3,(H,38,41)	KYQWHHSFDHBOKD-UHFFFAOYSA-N	793581	US20260055079, Example 89	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793581	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793581&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220317	528825044							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728977	Cc1cccc(Oc2ccc3c(=O)[nH]nc(Cc4ccc(F)c(C(=O)N5CCN(c6ccc(C#N)cn6)CC5)c4)c3c2)c1	InChI=1S/C33H27FN6O3/c1-21-3-2-4-24(15-21)43-25-7-8-26-27(18-25)30(37-38-32(26)41)17-22-5-9-29(34)28(16-22)33(42)40-13-11-39(12-14-40)31-10-6-23(19-35)20-36-31/h2-10,15-16,18,20H,11-14,17H2,1H3,(H,38,41)	ZTPFGWDNSNXEAN-UHFFFAOYSA-N	793582	US20260055079, Example 90	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793582	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793582&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219648	528825045							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728978	COc1cc2c(Cc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)n[nH]c(=O)c2cn1	InChI=1S/C26H22FN7O3/c1-37-24-12-18-20(15-30-24)25(35)32-31-22(18)11-16-2-4-21(27)19(10-16)26(36)34-8-6-33(7-9-34)23-5-3-17(13-28)14-29-23/h2-5,10,12,14-15H,6-9,11H2,1H3,(H,32,35)	FTJSRHBJTXICLM-UHFFFAOYSA-N	793583	US20260055079, Example 91	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793583	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793583&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219573	528825046							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728979	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5cccnc45)ccc3F)CC2)nc1	InChI=1S/C25H20FN7O2/c26-20-5-3-16(13-21-23-18(2-1-7-28-23)24(34)31-30-21)12-19(20)25(35)33-10-8-32(9-11-33)22-6-4-17(14-27)15-29-22/h1-7,12,15H,8-11,13H2,(H,31,34)	ZIEGUVVUYJRROD-UHFFFAOYSA-N	793584	US20260055079, Example 92	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793584	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793584&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220032	528825047							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728980	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5c(C(F)(F)F)cc(OC6CCC6)cc45)ccc3F)CC2)nc1	InChI=1S/C31H26F4N6O3/c32-25-6-4-18(12-22(25)30(43)41-10-8-40(9-11-41)27-7-5-19(16-36)17-37-27)13-26-23-14-21(44-20-2-1-3-20)15-24(31(33,34)35)28(23)29(42)39-38-26/h4-7,12,14-15,17,20H,1-3,8-11,13H2,(H,39,42)	BRUYMSHJGIFTFA-UHFFFAOYSA-N	793585	US20260055079, Example 93	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793585	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793585&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220197	528825048							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728981	N#Cc1ccc(N2CCCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)nc1	InChI=1S/C31H29FN6O3/c32-27-9-5-20(16-28-25-17-23(41-22-3-1-4-22)7-8-24(25)30(39)36-35-28)15-26(27)31(40)38-12-2-11-37(13-14-38)29-10-6-21(18-33)19-34-29/h5-10,15,17,19,22H,1-4,11-14,16H2,(H,36,39)	HQCGASWIMKKMST-UHFFFAOYSA-N	793586	US20260055079, Example 94	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793586	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793586&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219978	528825049							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728982	N#Cc1ccnc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)c1	InChI=1S/C30H27FN6O3/c31-26-7-4-19(15-27-24-17-22(40-21-2-1-3-21)5-6-23(24)29(38)35-34-27)14-25(26)30(39)37-12-10-36(11-13-37)28-16-20(18-32)8-9-33-28/h4-9,14,16-17,21H,1-3,10-13,15H2,(H,35,38)	OPICBFPCDVMSNC-UHFFFAOYSA-N	793587	US20260055079, Example 95	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793587	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793587&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220315	528825050							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728983	N#Cc1ccc(N2C[C@H]3CC[C@@H](C2)N3C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)nc1	InChI=1S/C32H29FN6O3/c33-28-10-4-19(13-29-26-14-24(42-23-2-1-3-23)8-9-25(26)31(40)37-36-29)12-27(28)32(41)39-21-6-7-22(39)18-38(17-21)30-11-5-20(15-34)16-35-30/h4-5,8-12,14,16,21-23H,1-3,6-7,13,17-18H2,(H,37,40)	PUVVJPKUNBISEJ-UHFFFAOYSA-N	793588	US20260055079, Example 96	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793588	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793588&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219474	528825051							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728984	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1[C@@H]2CC[C@H]1CN(c1ncc(C(F)(F)F)cn1)C2	InChI=1S/C31H28F4N6O3/c32-26-9-4-17(11-27-24-12-22(44-21-2-1-3-21)7-8-23(24)28(42)39-38-27)10-25(26)29(43)41-19-5-6-20(41)16-40(15-19)30-36-13-18(14-37-30)31(33,34)35/h4,7-10,12-14,19-21H,1-3,5-6,11,15-16H2,(H,39,42)	GFFNKLCTHFWBGL-UHFFFAOYSA-N	793589	US20260055079, Example 97	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793589	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793589&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219988	528825052							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728985	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C30H28F4N6O3/c31-25-8-5-18(14-26-23-15-21(43-20-3-1-4-20)6-7-22(23)27(41)38-37-26)13-24(25)28(42)39-9-2-10-40(12-11-39)29-35-16-19(17-36-29)30(32,33)34/h5-8,13,15-17,20H,1-4,9-12,14H2,(H,38,41)	SOPSIIVASUXNEG-UHFFFAOYSA-N	793590	US20260055079, Example 98	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793590	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793590&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220311	528825053							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728986	N#Cc1cnc(N2[C@@H]3CC[C@H]2CN(C(=O)c2cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc2F)C3)nc1	InChI=1S/C31H28FN7O3/c32-27-9-4-18(11-28-25-12-23(42-22-2-1-3-22)7-8-24(25)29(40)37-36-28)10-26(27)30(41)38-16-20-5-6-21(17-38)39(20)31-34-14-19(13-33)15-35-31/h4,7-10,12,14-15,20-22H,1-3,5-6,11,16-17H2,(H,37,40)	YWLTXZZPKGRXFU-UHFFFAOYSA-N	793591	US20260055079, Example 99	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793591	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793591&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220380	528825054							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728987	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1C[C@H]2CC[C@@H](C1)N2c1ncc(C(F)(F)F)cn1	InChI=1S/C31H28F4N6O3/c32-26-9-4-17(11-27-24-12-22(44-21-2-1-3-21)7-8-23(24)28(42)39-38-27)10-25(26)29(43)40-15-19-5-6-20(16-40)41(19)30-36-13-18(14-37-30)31(33,34)35/h4,7-10,12-14,19-21H,1-3,5-6,11,15-16H2,(H,39,42)	DTYQCJZEMDXKFD-UHFFFAOYSA-N	793592	US20260055079, Example 100	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793592	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793592&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220095	528825055							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728988	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCCN(C(=O)C2CC2)CC1	InChI=1S/C29H31FN4O4/c30-25-10-5-18(15-24(25)29(37)34-12-2-11-33(13-14-34)28(36)19-6-7-19)16-26-23-17-21(38-20-3-1-4-20)8-9-22(23)27(35)32-31-26/h5,8-10,15,17,19-20H,1-4,6-7,11-14,16H2,(H,32,35)	UEVMMQGFGOUVSE-UHFFFAOYSA-N	793593	US20260055079, Example 101	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793593	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793593&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219906	528825056							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728989	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CC(Nc2ncc(C(F)(F)F)cn2)C1	InChI=1S/C28H24F4N6O3/c29-23-7-4-15(9-24-21-10-19(41-18-2-1-3-18)5-6-20(21)25(39)37-36-24)8-22(23)26(40)38-13-17(14-38)35-27-33-11-16(12-34-27)28(30,31)32/h4-8,10-12,17-18H,1-3,9,13-14H2,(H,37,39)(H,33,34,35)	XJDVSDLJLNGXOO-UHFFFAOYSA-N	793594	US20260055079, Example 102	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793594	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793594&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220357	528825057							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728990	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCC2C1CCN2c1ncc(C(F)(F)F)cn1	InChI=1S/C31H28F4N6O3/c32-24-7-4-17(13-25-22-14-20(44-19-2-1-3-19)5-6-21(22)28(42)39-38-25)12-23(24)29(43)40-10-8-27-26(40)9-11-41(27)30-36-15-18(16-37-30)31(33,34)35/h4-7,12,14-16,19,26-27H,1-3,8-11,13H2,(H,39,42)	YVVHKQIDJXODAG-UHFFFAOYSA-N	793595	US20260055079, Example 103	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793595	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793595&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219803	528825058							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728991	N#Cc1ccc(NC2CN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)C2)nc1	InChI=1S/C29H25FN6O3/c30-25-8-4-17(10-24(25)29(38)36-15-19(16-36)33-27-9-5-18(13-31)14-32-27)11-26-23-12-21(39-20-2-1-3-20)6-7-22(23)28(37)35-34-26/h4-10,12,14,19-20H,1-3,11,15-16H2,(H,32,33)(H,35,37)	OMSPVVRWHBWCIR-UHFFFAOYSA-N	793596	US20260055079, Example 104	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793596	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793596&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219899	528825059							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728992	CN(c1cc(C#N)ccn1)C1CN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)C1	InChI=1S/C30H27FN6O3/c1-36(28-13-19(15-32)9-10-33-28)20-16-37(17-20)30(39)25-11-18(5-8-26(25)31)12-27-24-14-22(40-21-3-2-4-21)6-7-23(24)29(38)35-34-27/h5-11,13-14,20-21H,2-4,12,16-17H2,1H3,(H,35,38)	DIHDVGFZOGFAJN-UHFFFAOYSA-N	793597	US20260055079, Example 105	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793597	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793597&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220390	528825060							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728993	N#Cc1ccnc(NC2CN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)C2)c1	InChI=1S/C29H25FN6O3/c30-25-7-4-17(10-24(25)29(38)36-15-19(16-36)33-27-12-18(14-31)8-9-32-27)11-26-23-13-21(39-20-2-1-3-20)5-6-22(23)28(37)35-34-26/h4-10,12-13,19-20H,1-3,11,15-16H2,(H,32,33)(H,35,37)	SEKZVWSRIYPPQZ-UHFFFAOYSA-N	793598	US20260055079, Example 106	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793598	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793598&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219971	528825061							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728994	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1C[C@H]2CC[C@@H](C1)N2C(=O)C1CC1	InChI=1S/C30H31FN4O4/c31-26-11-4-17(13-27-24-14-22(39-21-2-1-3-21)9-10-23(24)28(36)33-32-27)12-25(26)30(38)34-15-19-7-8-20(16-34)35(19)29(37)18-5-6-18/h4,9-12,14,18-21H,1-3,5-8,13,15-16H2,(H,33,36)	CGWQWCBRZIDYKE-UHFFFAOYSA-N	793599	US20260055079, Example 107	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793599	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793599&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219520	528825062							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728995	CNC(=O)c1ccnc(N(C)C2CN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)C2)n1	InChI=1S/C30H30FN7O4/c1-32-28(40)25-10-11-33-30(34-25)37(2)18-15-38(16-18)29(41)23-12-17(6-9-24(23)31)13-26-22-14-20(42-19-4-3-5-19)7-8-21(22)27(39)36-35-26/h6-12,14,18-19H,3-5,13,15-16H2,1-2H3,(H,32,40)(H,36,39)	XBAOOSGJHNGLCP-UHFFFAOYSA-N	793600	US20260055079, Example 108	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793600	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793600&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219662	528825063							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728996	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCC2C1CCN2C(=O)C1CC1	InChI=1S/C30H31FN4O4/c31-24-9-4-17(15-25-22-16-20(39-19-2-1-3-19)7-8-21(22)28(36)33-32-25)14-23(24)30(38)35-13-11-26-27(35)10-12-34(26)29(37)18-5-6-18/h4,7-9,14,16,18-19,26-27H,1-3,5-6,10-13,15H2,(H,33,36)	AAANCYIHVWFWGM-UHFFFAOYSA-N	793602	US20260055079, Example 109	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793602	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793602&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220362	528825065							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728997	Cc1cnc(N(C)C2CN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)C2)n1C	InChI=1S/C29H31FN6O3/c1-17-14-31-29(34(17)2)35(3)19-15-36(16-19)28(38)24-11-18(7-10-25(24)30)12-26-23-13-21(39-20-5-4-6-20)8-9-22(23)27(37)33-32-26/h7-11,13-14,19-20H,4-6,12,15-16H2,1-3H3,(H,33,37)	RIDGCUBNAKLUCT-UHFFFAOYSA-N	793603	US20260055079, Example 110	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793603	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793603&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220372	528825066							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728998	N#Cc1ccc(N2CCC3C2CCN3C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)nc1	InChI=1S/C32H29FN6O3/c33-26-8-4-19(15-27-24-16-22(42-21-2-1-3-21)6-7-23(24)31(40)37-36-27)14-25(26)32(41)39-13-11-28-29(39)10-12-38(28)30-9-5-20(17-34)18-35-30/h4-9,14,16,18,21,28-29H,1-3,10-13,15H2,(H,37,40)	HRQQWIUAFWNWSH-UHFFFAOYSA-N	793604	US20260055079, Example 111	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793604	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793604&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220056	528825067							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728999	O=C(C1CC1)N1C[C@H]2CC[C@@H](C1)N2C(=O)c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F	InChI=1S/C30H31FN4O4/c31-26-11-4-17(13-27-24-14-22(39-21-2-1-3-21)9-10-23(24)28(36)33-32-27)12-25(26)30(38)35-19-7-8-20(35)16-34(15-19)29(37)18-5-6-18/h4,9-12,14,18-21H,1-3,5-8,13,15-16H2,(H,33,36)	VZSWLTNSRWTPNX-UHFFFAOYSA-N	793605	US20260055079, Example 112	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793605	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793605&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220204	528825068							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729000	O=C(NC1CN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)C1)C1CC1	InChI=1S/C27H27FN4O4/c28-23-9-4-15(10-22(23)27(35)32-13-17(14-32)29-25(33)16-5-6-16)11-24-21-12-19(36-18-2-1-3-18)7-8-20(21)26(34)31-30-24/h4,7-10,12,16-18H,1-3,5-6,11,13-14H2,(H,29,33)(H,31,34)	SWPHJPNZGYPAQE-UHFFFAOYSA-N	793606	US20260055079, Example 113	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793606	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793606&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219747	528825069							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729001	CN(C(=O)CCC(F)(F)F)C1CN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)C1	InChI=1S/C28H28F4N4O4/c1-35(25(37)9-10-28(30,31)32)17-14-36(15-17)27(39)22-11-16(5-8-23(22)29)12-24-21-13-19(40-18-3-2-4-18)6-7-20(21)26(38)34-33-24/h5-8,11,13,17-18H,2-4,9-10,12,14-15H2,1H3,(H,34,38)	VZYDWKGHVDBIGT-UHFFFAOYSA-N	793607	US20260055079, Example 114	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793607	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793607&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220080	528825070							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729002	N#Cc1ccc(N2CC3CN(C(=O)c4cc(Cc5n[nH]c(=O)c6ccc(OC7CCC7)cc56)ccc4F)CC3C2)nc1	InChI=1S/C32H29FN6O3/c33-28-8-4-19(11-29-26-12-24(42-23-2-1-3-23)6-7-25(26)31(40)37-36-29)10-27(28)32(41)39-17-21-15-38(16-22(21)18-39)30-9-5-20(13-34)14-35-30/h4-10,12,14,21-23H,1-3,11,15-18H2,(H,37,40)	TZOSSHBSUNZYII-UHFFFAOYSA-N	793608	US20260055079, Example 115	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793608	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793608&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219666	528825071							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729003	CN(c1cncc(C#N)n1)C1CN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)C1	InChI=1S/C29H26FN7O3/c1-36(27-14-32-13-18(12-31)33-27)19-15-37(16-19)29(39)24-9-17(5-8-25(24)30)10-26-23-11-21(40-20-3-2-4-20)6-7-22(23)28(38)35-34-26/h5-9,11,13-14,19-20H,2-4,10,15-16H2,1H3,(H,35,38)	MHOOMWVOTCVOFO-UHFFFAOYSA-N	793609	US20260055079, Example 116	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793609	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793609&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220373	528825072							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729004	CN(C(=O)C1CCN1)C1CN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)C1	InChI=1S/C28H30FN5O4/c1-33(28(37)24-9-10-30-24)17-14-34(15-17)27(36)22-11-16(5-8-23(22)29)12-25-21-13-19(38-18-3-2-4-18)6-7-20(21)26(35)32-31-25/h5-8,11,13,17-18,24,30H,2-4,9-10,12,14-15H2,1H3,(H,32,35)	PPZMTKHTWIFZKT-UHFFFAOYSA-N	793610	US20260055079, Example 117	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793610	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793610&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219513	528825073							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729005	CN(C(=O)CC#N)C1CN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)C1	InChI=1S/C27H26FN5O4/c1-32(25(34)9-10-29)17-14-33(15-17)27(36)22-11-16(5-8-23(22)28)12-24-21-13-19(37-18-3-2-4-18)6-7-20(21)26(35)31-30-24/h5-8,11,13,17-18H,2-4,9,12,14-15H2,1H3,(H,31,35)	WLKNPFNVOWOSIX-UHFFFAOYSA-N	793611	US20260055079, Example 118	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793611	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793611&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219781	528825074							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729006	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CC2CN(C(=O)C3CC3)CC2C1	InChI=1S/C30H31FN4O4/c31-26-9-4-17(11-27-24-12-22(39-21-2-1-3-21)7-8-23(24)28(36)33-32-27)10-25(26)30(38)35-15-19-13-34(14-20(19)16-35)29(37)18-5-6-18/h4,7-10,12,18-21H,1-3,5-6,11,13-16H2,(H,33,36)	JETUTOVBUQOUCS-UHFFFAOYSA-N	793612	US20260055079, Example 119	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793612	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793612&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219900	528825075							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729007	CN(c1nccc(C(F)(F)F)n1)C1CN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)C1	InChI=1S/C29H26F4N6O3/c1-38(28-34-10-9-25(35-28)29(31,32)33)17-14-39(15-17)27(41)22-11-16(5-8-23(22)30)12-24-21-13-19(42-18-3-2-4-18)6-7-20(21)26(40)37-36-24/h5-11,13,17-18H,2-4,12,14-15H2,1H3,(H,37,40)	FYOKAMXTOWZXRA-UHFFFAOYSA-N	793613	US20260055079, Example 120	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793613	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793613&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219936	528825076							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729008	CN(C(=O)C1CC1)C1CN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)C1	InChI=1S/C28H29FN4O4/c1-32(27(35)17-6-7-17)18-14-33(15-18)28(36)23-11-16(5-10-24(23)29)12-25-22-13-20(37-19-3-2-4-19)8-9-21(22)26(34)31-30-25/h5,8-11,13,17-19H,2-4,6-7,12,14-15H2,1H3,(H,31,34)	DOZHGVQKIJUUPI-UHFFFAOYSA-N	793614	US20260055079, Example 121	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793614	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793614&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219999	528825077							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729009	CN(C(=O)C1CCO1)C1CN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)C1	InChI=1S/C28H29FN4O5/c1-32(28(36)25-9-10-37-25)17-14-33(15-17)27(35)22-11-16(5-8-23(22)29)12-24-21-13-19(38-18-3-2-4-18)6-7-20(21)26(34)31-30-24/h5-8,11,13,17-18,25H,2-4,9-10,12,14-15H2,1H3,(H,31,34)	MIVUOYIECOAVLK-UHFFFAOYSA-N	793615	US20260055079, Example 122	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793615	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793615&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220209	528825078							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729010	CNC(=O)c1ccnc(N(C)C2CN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)C2)c1	InChI=1S/C31H31FN6O4/c1-33-29(39)19-10-11-34-28(14-19)37(2)20-16-38(17-20)31(41)25-12-18(6-9-26(25)32)13-27-24-15-22(42-21-4-3-5-21)7-8-23(24)30(40)36-35-27/h6-12,14-15,20-21H,3-5,13,16-17H2,1-2H3,(H,33,39)(H,36,40)	DICYUIMPLAJZCY-UHFFFAOYSA-N	793616	US20260055079, Example 123	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793616	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793616&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219945	528825079							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729011	CN(c1cc(C#N)ccn1)C1CN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5COC5)cc34)ccc2F)C1	InChI=1S/C29H25FN6O4/c1-35(27-10-18(12-31)6-7-32-27)19-13-36(14-19)29(38)24-8-17(2-5-25(24)30)9-26-23-11-20(40-21-15-39-16-21)3-4-22(23)28(37)34-33-26/h2-8,10-11,19,21H,9,13-16H2,1H3,(H,34,37)	OCDATOIEMWVRIO-UHFFFAOYSA-N	793617	US20260055079, Example 124	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793617	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793617&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219463	528825080							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729012	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCN(c2ccc(C(F)(F)F)cn2)CC(F)(F)C1	InChI=1S/C31H27F6N5O3/c32-25-8-4-18(13-26-23-14-21(45-20-2-1-3-20)6-7-22(23)28(43)40-39-26)12-24(25)29(44)42-11-10-41(16-30(33,34)17-42)27-9-5-19(15-38-27)31(35,36)37/h4-9,12,14-15,20H,1-3,10-11,13,16-17H2,(H,40,43)	OXSWTELIRGVMCH-UHFFFAOYSA-N	793618	US20260055079, Example 125	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793618	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793618&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			178422887	528825081							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729013	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCN(c2ncc(C(F)(F)F)cn2)CC(F)(F)C1	InChI=1S/C30H26F6N6O3/c31-24-7-4-17(11-25-22-12-20(45-19-2-1-3-19)5-6-21(22)26(43)40-39-25)10-23(24)27(44)41-8-9-42(16-29(32,33)15-41)28-37-13-18(14-38-28)30(34,35)36/h4-7,10,12-14,19H,1-3,8-9,11,15-16H2,(H,40,43)	FQOQTWBWKSIBDC-UHFFFAOYSA-N	793619	US20260055079, Example 126	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793619	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793619&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220065	528825082							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729014	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCN(C(=O)C2CC2)CC(F)(F)C1	InChI=1S/C29H29F3N4O4/c30-24-9-4-17(13-25-22-14-20(40-19-2-1-3-19)7-8-21(22)26(37)34-33-25)12-23(24)28(39)36-11-10-35(15-29(31,32)16-36)27(38)18-5-6-18/h4,7-9,12,14,18-19H,1-3,5-6,10-11,13,15-16H2,(H,34,37)	GGYHZCYMDPABBA-UHFFFAOYSA-N	793620	US20260055079, Example 127	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793620	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793620&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220307	528825083							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729015	COc1ccnc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)c1	InChI=1S/C30H30FN5O4/c1-39-21-9-10-32-28(18-21)35-11-13-36(14-12-35)30(38)25-15-19(5-8-26(25)31)16-27-24-17-22(40-20-3-2-4-20)6-7-23(24)29(37)34-33-27/h5-10,15,17-18,20H,2-4,11-14,16H2,1H3,(H,34,37)	GOERRIJFVYKXTO-UHFFFAOYSA-N	793621	US20260055079, Example 128	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793621	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793621&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220109	528825084							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729016	N#Cc1cnc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)c(C(F)(F)F)c1	InChI=1S/C31H26F4N6O3/c32-26-7-4-18(14-27-23-15-21(44-20-2-1-3-20)5-6-22(23)29(42)39-38-27)12-24(26)30(43)41-10-8-40(9-11-41)28-25(31(33,34)35)13-19(16-36)17-37-28/h4-7,12-13,15,17,20H,1-3,8-11,14H2,(H,39,42)	GJJYFCNJHDUZDL-UHFFFAOYSA-N	793622	US20260055079, Example 129	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793622	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793622&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219530	528825085							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729017	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCN(c2ccc(CO)cn2)CC1	InChI=1S/C30H30FN5O4/c31-26-8-4-19(15-27-24-16-22(40-21-2-1-3-21)6-7-23(24)29(38)34-33-27)14-25(26)30(39)36-12-10-35(11-13-36)28-9-5-20(18-37)17-32-28/h4-9,14,16-17,21,37H,1-3,10-13,15,18H2,(H,34,38)	BRJOEJAJPSJMJM-UHFFFAOYSA-N	793623	US20260055079, Example 130	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793623	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793623&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219780	528825086							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729018	COc1cc(C#N)cnc1N1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)CC1	InChI=1S/C31H29FN6O4/c1-41-28-15-20(17-33)18-34-29(28)37-9-11-38(12-10-37)31(40)25-13-19(5-8-26(25)32)14-27-24-16-22(42-21-3-2-4-21)6-7-23(24)30(39)36-35-27/h5-8,13,15-16,18,21H,2-4,9-12,14H2,1H3,(H,36,39)	SSZKLFDCQILRMD-UHFFFAOYSA-N	793624	US20260055079, Example 131	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793624	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793624&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219634	528825087							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729019	N#Cc1cnc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)cc1C(F)(F)F	InChI=1S/C31H26F4N6O3/c32-26-7-4-18(13-27-23-14-21(44-20-2-1-3-20)5-6-22(23)29(42)39-38-27)12-24(26)30(43)41-10-8-40(9-11-41)28-15-25(31(33,34)35)19(16-36)17-37-28/h4-7,12,14-15,17,20H,1-3,8-11,13H2,(H,39,42)	JDONPPOPPXRORX-UHFFFAOYSA-N	793625	US20260055079, Example 132	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793625	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793625&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220284	528825088							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729020	N#Cc1cnc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)cc1C(F)(F)F	InChI=1S/C31H26F4N6O3/c32-26-7-4-18(13-27-23-14-21(44-20-2-1-3-20)5-6-22(23)29(42)39-38-27)12-24(26)30(43)41-10-8-40(9-11-41)28-15-25(31(33,34)35)19(16-36)17-37-28/h4-7,12,14-15,17,20H,1-3,8-11,13H2,(H,39,42)	JDONPPOPPXRORX-UHFFFAOYSA-N	793625	US20260055079, Example 132	Poly [ADP-ribose] polymerase 1	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793625	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=232&target=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793625&enzyme=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search			169220284	528825088							1	MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW	9MJA,9MI8,4OQB,4OQA,4OPX,4DQY,8G0H,7S6M,7S6H,5A00,4ZZZ,4XHU,6XVW,5HA9,4PJT,2RCW,1WOK,1UK1,1UK0,6I8T,6I8M,7S81,7S68,6M3I,9DMC,9BPY,8FZ1,8FYZ,8FYY,6NTU,6NRJ,6NRI,6NRH,6NRG,6NRF,6BHV,5DS3,8U4W,2N8A,2RIQ,2JVN,2CR9,2CS2,2L31,2L30,3ODE,3ODC,7SCZ,7SCY,3ODA,3OD8,2DMJ,9UMC,9UMF	Poly [ADP-ribose] polymerase 1	PARP1_HUMAN	P09874	B1ANJ4 Q8IUZ9			N/A	A0A024R3T8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729021	N#Cc1cnc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)cc1C(F)(F)F	InChI=1S/C31H26F4N6O3/c32-26-7-4-18(13-27-23-14-21(44-20-2-1-3-20)5-6-22(23)29(42)39-38-27)12-24(26)30(43)41-10-8-40(9-11-41)28-15-25(31(33,34)35)19(16-36)17-37-28/h4-7,12,14-15,17,20H,1-3,8-11,13H2,(H,39,42)	JDONPPOPPXRORX-UHFFFAOYSA-N	793625	US20260055079, Example 132	Poly [ADP-ribose] polymerase 2	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793625	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793625&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220284	528825088							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729022	Cc1nc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)ccc1C#N	InChI=1S/C31H29FN6O3/c1-19-21(18-33)6-10-29(34-19)37-11-13-38(14-12-37)31(40)26-15-20(5-9-27(26)32)16-28-25-17-23(41-22-3-2-4-22)7-8-24(25)30(39)36-35-28/h5-10,15,17,22H,2-4,11-14,16H2,1H3,(H,36,39)	JNOJALSESIXIPI-UHFFFAOYSA-N	793626	US20260055079, Example 133	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793626	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793626&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220404	528825089							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729023	Cc1cc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)ncc1C#N	InChI=1S/C31H29FN6O3/c1-19-13-29(34-18-21(19)17-33)37-9-11-38(12-10-37)31(40)26-14-20(5-8-27(26)32)15-28-25-16-23(41-22-3-2-4-22)6-7-24(25)30(39)36-35-28/h5-8,13-14,16,18,22H,2-4,9-12,15H2,1H3,(H,36,39)	NWEFDLWGEIFICU-UHFFFAOYSA-N	793627	US20260055079, Example 134	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793627	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793627&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220411	528825090							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729024	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)nc1C(F)(F)F	InChI=1S/C31H26F4N6O3/c32-25-8-4-18(15-26-23-16-21(44-20-2-1-3-20)6-7-22(23)29(42)39-38-26)14-24(25)30(43)41-12-10-40(11-13-41)27-9-5-19(17-36)28(37-27)31(33,34)35/h4-9,14,16,20H,1-3,10-13,15H2,(H,39,42)	CGIDWBWCAFWWIQ-UHFFFAOYSA-N	793628	US20260055079, Example 135	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793628	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793628&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219802	528825091							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729025	COc1nc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)ccc1C#N	InChI=1S/C31H29FN6O4/c1-41-30-20(18-33)6-10-28(34-30)37-11-13-38(14-12-37)31(40)25-15-19(5-9-26(25)32)16-27-24-17-22(42-21-3-2-4-21)7-8-23(24)29(39)36-35-27/h5-10,15,17,21H,2-4,11-14,16H2,1H3,(H,36,39)	GXBXZDRHBXRGLB-UHFFFAOYSA-N	793629	US20260055079, Example 136	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793629	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793629&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219861	528825092							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729026	Cc1cc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)ncc1C#N	InChI=1S/C31H29FN6O3/c1-19-13-29(34-18-21(19)17-33)37-9-11-38(12-10-37)31(40)26-14-20(5-8-27(26)32)15-28-25-16-23(41-22-3-2-4-22)6-7-24(25)30(39)36-35-28/h5-8,13-14,16,18,22H,2-4,9-12,15H2,1H3,(H,36,39)	NWEFDLWGEIFICU-UHFFFAOYSA-N	793630	US20260055079, Example 137	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793630	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793630&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220411	528825093							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729027	Cc1cc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)ncc1C#N	InChI=1S/C31H29FN6O3/c1-19-13-29(34-18-21(19)17-33)37-9-11-38(12-10-37)31(40)26-14-20(5-8-27(26)32)15-28-25-16-23(41-22-3-2-4-22)6-7-24(25)30(39)36-35-28/h5-8,13-14,16,18,22H,2-4,9-12,15H2,1H3,(H,36,39)	NWEFDLWGEIFICU-UHFFFAOYSA-N	793630	US20260055079, Example 137	Poly [ADP-ribose] polymerase 1	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793630	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=232&target=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793630&enzyme=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search			169220411	528825093							1	MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW	9MJA,9MI8,4OQB,4OQA,4OPX,4DQY,8G0H,7S6M,7S6H,5A00,4ZZZ,4XHU,6XVW,5HA9,4PJT,2RCW,1WOK,1UK1,1UK0,6I8T,6I8M,7S81,7S68,6M3I,9DMC,9BPY,8FZ1,8FYZ,8FYY,6NTU,6NRJ,6NRI,6NRH,6NRG,6NRF,6BHV,5DS3,8U4W,2N8A,2RIQ,2JVN,2CR9,2CS2,2L31,2L30,3ODE,3ODC,7SCZ,7SCY,3ODA,3OD8,2DMJ,9UMC,9UMF	Poly [ADP-ribose] polymerase 1	PARP1_HUMAN	P09874	B1ANJ4 Q8IUZ9			N/A	A0A024R3T8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729028	Cc1cc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)ncc1C#N	InChI=1S/C31H29FN6O3/c1-19-13-29(34-18-21(19)17-33)37-9-11-38(12-10-37)31(40)26-14-20(5-8-27(26)32)15-28-25-16-23(41-22-3-2-4-22)6-7-24(25)30(39)36-35-28/h5-8,13-14,16,18,22H,2-4,9-12,15H2,1H3,(H,36,39)	NWEFDLWGEIFICU-UHFFFAOYSA-N	793630	US20260055079, Example 137	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793630	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793630&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220411	528825093							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729029	Cc1cc(C#N)cnc1N1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)CC1	InChI=1S/C31H29FN6O3/c1-19-13-21(17-33)18-34-29(19)37-9-11-38(12-10-37)31(40)26-14-20(5-8-27(26)32)15-28-25-16-23(41-22-3-2-4-22)6-7-24(25)30(39)36-35-28/h5-8,13-14,16,18,22H,2-4,9-12,15H2,1H3,(H,36,39)	FXDTWBPNDSVIIH-UHFFFAOYSA-N	793631	US20260055079, Example 138	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793631	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793631&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220022	528825094							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729030	N#Cc1ccc(-c2nnc3n2CCN(C(=O)c2cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc2F)C3)nc1	InChI=1S/C31H25FN8O3/c32-25-8-4-18(13-27-23-14-21(43-20-2-1-3-20)6-7-22(23)30(41)38-35-27)12-24(25)31(42)39-10-11-40-28(17-39)36-37-29(40)26-9-5-19(15-33)16-34-26/h4-9,12,14,16,20H,1-3,10-11,13,17H2,(H,38,41)	ZFHHCSIAIQRPFE-UHFFFAOYSA-N	793632	US20260055079, Example 139	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793632	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793632&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219765	528825095							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729031	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCN(c2ccc(O)cn2)CC1	InChI=1S/C29H28FN5O4/c30-25-8-4-18(14-24(25)29(38)35-12-10-34(11-13-35)27-9-5-19(36)17-31-27)15-26-23-16-21(39-20-2-1-3-20)6-7-22(23)28(37)33-32-26/h4-9,14,16-17,20,36H,1-3,10-13,15H2,(H,33,37)	KPGQZAGHDRRKRH-UHFFFAOYSA-N	793633	US20260055079, Example 140	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793633	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793633&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219508	528825096							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729032	N#Cc1cncc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)c1	InChI=1S/C30H27FN6O3/c31-27-7-4-19(14-28-25-15-23(40-22-2-1-3-22)5-6-24(25)29(38)35-34-28)13-26(27)30(39)37-10-8-36(9-11-37)21-12-20(16-32)17-33-18-21/h4-7,12-13,15,17-18,22H,1-3,8-11,14H2,(H,35,38)	FDEQBONPTPVWOB-UHFFFAOYSA-N	793634	US20260055079, Example 141	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793634	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793634&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220349	528825097							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729033	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1C[C@@H]2CC[C@H]1CN2C(=O)C1CC1	InChI=1S/C30H31FN4O4/c31-26-11-4-17(13-27-24-14-22(39-21-2-1-3-21)9-10-23(24)28(36)33-32-27)12-25(26)30(38)35-16-19-7-8-20(35)15-34(19)29(37)18-5-6-18/h4,9-12,14,18-21H,1-3,5-8,13,15-16H2,(H,33,36)	IMDUZYDRTZFVOD-UHFFFAOYSA-N	793635	US20260055079, Example 142	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793635	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793635&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220175	528825098							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729034	N#Cc1ccc(N2C[C@@H]3CC[C@H]2CN3C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)nc1	InChI=1S/C32H29FN6O3/c33-28-10-4-19(13-29-26-14-24(42-23-2-1-3-23)8-9-25(26)31(40)37-36-29)12-27(28)32(41)39-18-21-6-7-22(39)17-38(21)30-11-5-20(15-34)16-35-30/h4-5,8-12,14,16,21-23H,1-3,6-7,13,17-18H2,(H,37,40)	AIVVNPKCZOQDNS-UHFFFAOYSA-N	793636	US20260055079, Example 143	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793636	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793636&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219668	528825099							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729035	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1C[C@@H]2CC[C@H]1CN2c1ncc(C(F)(F)F)cn1	InChI=1S/C31H28F4N6O3/c32-26-9-4-17(11-27-24-12-22(44-21-2-1-3-21)7-8-23(24)28(42)39-38-27)10-25(26)29(43)40-15-20-6-5-19(40)16-41(20)30-36-13-18(14-37-30)31(33,34)35/h4,7-10,12-14,19-21H,1-3,5-6,11,15-16H2,(H,39,42)	BVOHFFWFYSVTEJ-UHFFFAOYSA-N	793637	US20260055079, Example 144	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793637	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793637&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219592	528825100							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729036	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCn2c(nnc2C(F)(F)F)C1	InChI=1S/C26H22F4N6O3/c27-20-7-4-14(10-19(20)24(38)35-8-9-36-22(13-35)32-34-25(36)26(28,29)30)11-21-18-12-16(39-15-2-1-3-15)5-6-17(18)23(37)33-31-21/h4-7,10,12,15H,1-3,8-9,11,13H2,(H,33,37)	XWGJSPPBACNIPS-UHFFFAOYSA-N	793638	US20260055079, Example 145	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793638	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793638&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219489	528825101							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729037	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCn2c(nnc2C2CC2)C1	InChI=1S/C28H27FN6O3/c29-23-9-4-16(12-22(23)28(37)34-10-11-35-25(15-34)31-32-26(35)17-5-6-17)13-24-21-14-19(38-18-2-1-3-18)7-8-20(21)27(36)33-30-24/h4,7-9,12,14,17-18H,1-3,5-6,10-11,13,15H2,(H,33,36)	CLVAUOBZCCAZHQ-UHFFFAOYSA-N	793639	US20260055079, Example 146	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793639	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793639&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220043	528825102							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729038	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CC2CN(c3ncc(C(F)(F)F)cn3)CC2C1	InChI=1S/C31H28F4N6O3/c32-26-7-4-17(9-27-24-10-22(44-21-2-1-3-21)5-6-23(24)28(42)39-38-27)8-25(26)29(43)40-13-18-15-41(16-19(18)14-40)30-36-11-20(12-37-30)31(33,34)35/h4-8,10-12,18-19,21H,1-3,9,13-16H2,(H,39,42)	ROZCUTPMQCSMLD-UHFFFAOYSA-N	793640	US20260055079, Example 147	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793640	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793640&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220279	528825103							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729039	N#Cc1ccc(N2CC3(CN(C(=O)c4cc(Cc5n[nH]c(=O)c6ccc(OC7CCC7)cc56)ccc4F)C3)C2)nc1	InChI=1S/C31H27FN6O3/c32-26-8-4-19(11-27-24-12-22(41-21-2-1-3-21)6-7-23(24)29(39)36-35-27)10-25(26)30(40)38-17-31(18-38)15-37(16-31)28-9-5-20(13-33)14-34-28/h4-10,12,14,21H,1-3,11,15-18H2,(H,36,39)	WJANPUWCCNQGLL-UHFFFAOYSA-N	793641	US20260055079, Example 148	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793641	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793641&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220006	528825104							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729040	N#Cc1ccc(N2CCCC23CN(C(=O)c2cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc2F)C3)nc1	InChI=1S/C32H29FN6O3/c33-27-9-5-20(14-28-25-15-23(42-22-3-1-4-22)7-8-24(25)30(40)37-36-28)13-26(27)31(41)38-18-32(19-38)11-2-12-39(32)29-10-6-21(16-34)17-35-29/h5-10,13,15,17,22H,1-4,11-12,14,18-19H2,(H,37,40)	XASUUGPXCVJCCE-UHFFFAOYSA-N	793642	US20260055079, Example 149	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793642	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793642&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220297	528825105							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729041	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)[C@@H]3C[C@@H]32)nc1	InChI=1S/C31H27FN6O3/c32-25-8-4-18(13-26-23-14-21(41-20-2-1-3-20)6-7-22(23)30(39)36-35-26)12-24(25)31(40)38-11-10-37(27-15-28(27)38)29-9-5-19(16-33)17-34-29/h4-9,12,14,17,20,27-28H,1-3,10-11,13,15H2,(H,36,39)	CPGBPIXLGPMHSC-UHFFFAOYSA-N	793643	US20260055079, Example 150	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793643	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793643&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219756	528825106							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729042	N#Cc1cnc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)nc1	InChI=1S/C29H26FN7O3/c30-25-7-4-18(13-26-23-14-21(40-20-2-1-3-20)5-6-22(23)27(38)35-34-26)12-24(25)28(39)36-8-10-37(11-9-36)29-32-16-19(15-31)17-33-29/h4-7,12,14,16-17,20H,1-3,8-11,13H2,(H,35,38)	ZSHMPVAMMQXKJB-UHFFFAOYSA-N	793644	US20260055079, Example 154	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793644	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793644&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220060	528825107							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729043	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCN(c2ccc(C(F)(F)F)cn2)CC1	InChI=1S/C30H27F4N5O3/c31-25-8-4-18(15-26-23-16-21(42-20-2-1-3-20)6-7-22(23)28(40)37-36-26)14-24(25)29(41)39-12-10-38(11-13-39)27-9-5-19(17-35-27)30(32,33)34/h4-9,14,16-17,20H,1-3,10-13,15H2,(H,37,40)	AZBPSNXTFDKFRU-UHFFFAOYSA-N	793645	US20260055079, Example 155	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793645	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793645&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219804	528825108							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729044	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCN(c2cc(C(F)(F)F)ccn2)CC1	InChI=1S/C30H27F4N5O3/c31-25-7-4-18(15-26-23-17-21(42-20-2-1-3-20)5-6-22(23)28(40)37-36-26)14-24(25)29(41)39-12-10-38(11-13-39)27-16-19(8-9-35-27)30(32,33)34/h4-9,14,16-17,20H,1-3,10-13,15H2,(H,37,40)	JYWWRLAAXSRTNN-UHFFFAOYSA-N	793646	US20260055079, Example 156	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793646	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793646&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220251	528825109							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729045	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCN(c2ncc(C(F)F)cn2)CC1	InChI=1S/C29H27F3N6O3/c30-24-7-4-17(13-25-22-14-20(41-19-2-1-3-19)5-6-21(22)27(39)36-35-25)12-23(24)28(40)37-8-10-38(11-9-37)29-33-15-18(16-34-29)26(31)32/h4-7,12,14-16,19,26H,1-3,8-11,13H2,(H,36,39)	MVUPFDFGRUKUAB-UHFFFAOYSA-N	793647	US20260055079, Example 157	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793647	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793647&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219675	528825110							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729046	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCN(c2ccc(C(F)(F)F)nn2)CC1	InChI=1S/C29H26F4N6O3/c30-23-7-4-17(15-24-21-16-19(42-18-2-1-3-18)5-6-20(21)27(40)37-34-24)14-22(23)28(41)39-12-10-38(11-13-39)26-9-8-25(35-36-26)29(31,32)33/h4-9,14,16,18H,1-3,10-13,15H2,(H,37,40)	VXRXFPOEJWFSGO-UHFFFAOYSA-N	793648	US20260055079, Example 158	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793648	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793648&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219741	528825111							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729047	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCN(c2ccc(C(F)(F)F)nc2)CC1	InChI=1S/C30H27F4N5O3/c31-25-8-4-18(15-26-23-16-21(42-20-2-1-3-20)6-7-22(23)28(40)37-36-26)14-24(25)29(41)39-12-10-38(11-13-39)19-5-9-27(35-17-19)30(32,33)34/h4-9,14,16-17,20H,1-3,10-13,15H2,(H,37,40)	CXBAALHPAKIMNM-UHFFFAOYSA-N	793649	US20260055079, Example 159	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793649	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793649&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219673	528825112							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729048	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCN(c2cnc(C(F)(F)F)cn2)CC1	InChI=1S/C29H26F4N6O3/c30-23-7-4-17(13-24-21-14-19(42-18-2-1-3-18)5-6-20(21)27(40)37-36-24)12-22(23)28(41)39-10-8-38(9-11-39)26-16-34-25(15-35-26)29(31,32)33/h4-7,12,14-16,18H,1-3,8-11,13H2,(H,37,40)	MOSROXTXIWNVAB-UHFFFAOYSA-N	793650	US20260055079, Example 160	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793650	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793650&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220136	528825113							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729049	CC(F)(F)c1cnc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)CC2)nc1	InChI=1S/C30H29F3N6O3/c1-30(32,33)19-16-34-29(35-17-19)39-11-9-38(10-12-39)28(41)24-13-18(5-8-25(24)31)14-26-23-15-21(42-20-3-2-4-20)6-7-22(23)27(40)37-36-26/h5-8,13,15-17,20H,2-4,9-12,14H2,1H3,(H,37,40)	WEQAOSBMXPNGCZ-UHFFFAOYSA-N	793651	US20260055079, Example 161	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793651	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793651&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220244	528825114							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729050	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCN(c2ncc(C3CC3)cn2)CC1	InChI=1S/C31H31FN6O3/c32-27-9-4-19(15-28-25-16-23(41-22-2-1-3-22)7-8-24(25)29(39)36-35-28)14-26(27)30(40)37-10-12-38(13-11-37)31-33-17-21(18-34-31)20-5-6-20/h4,7-9,14,16-18,20,22H,1-3,5-6,10-13,15H2,(H,36,39)	DPSQKZISAGEPFK-UHFFFAOYSA-N	793652	US20260055079, Example 162	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793652	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793652&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220388	528825115							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729051	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCn2c(nnc2C(F)F)C1	InChI=1S/C26H23F3N6O3/c27-20-7-4-14(10-19(20)26(37)34-8-9-35-22(13-34)31-32-24(35)23(28)29)11-21-18-12-16(38-15-2-1-3-15)5-6-17(18)25(36)33-30-21/h4-7,10,12,15,23H,1-3,8-9,11,13H2,(H,33,36)	NHSSSWXXJPWESA-UHFFFAOYSA-N	793653	US20260055079, Example 163	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793653	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793653&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219939	528825116							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729052	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCn2c(CF)nnc2C1	InChI=1S/C26H24F2N6O3/c27-13-23-30-31-24-14-33(8-9-34(23)24)26(36)20-10-15(4-7-21(20)28)11-22-19-12-17(37-16-2-1-3-16)5-6-18(19)25(35)32-29-22/h4-7,10,12,16H,1-3,8-9,11,13-14H2,(H,32,35)	AMFOPJHWVOCJPM-UHFFFAOYSA-N	793654	US20260055079, Example 164	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793654	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793654&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220326	528825117							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729053	COc1nnc2n1CCN(C(=O)c1cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc1F)C2	InChI=1S/C26H25FN6O4/c1-36-26-31-29-23-14-32(9-10-33(23)26)25(35)20-11-15(5-8-21(20)27)12-22-19-13-17(37-16-3-2-4-16)6-7-18(19)24(34)30-28-22/h5-8,11,13,16H,2-4,9-10,12,14H2,1H3,(H,30,34)	FEKTYWOCTWSXTG-UHFFFAOYSA-N	793655	US20260055079, Example 165	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793655	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793655&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220302	528825118							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729054	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCn2c(CO)nnc2C1	InChI=1S/C26H25FN6O4/c27-21-7-4-15(10-20(21)26(36)32-8-9-33-23(13-32)29-30-24(33)14-34)11-22-19-12-17(37-16-2-1-3-16)5-6-18(19)25(35)31-28-22/h4-7,10,12,16,34H,1-3,8-9,11,13-14H2,(H,31,35)	QCZWECUJAFNENN-UHFFFAOYSA-N	793656	US20260055079, Example 166	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793656	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793656&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220353	528825119							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729055	COCc1nnc2n1CCN(C(=O)c1cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc1F)C2	InChI=1S/C27H27FN6O4/c1-37-15-25-31-30-24-14-33(9-10-34(24)25)27(36)21-11-16(5-8-22(21)28)12-23-20-13-18(38-17-3-2-4-17)6-7-19(20)26(35)32-29-23/h5-8,11,13,17H,2-4,9-10,12,14-15H2,1H3,(H,32,35)	CZKLYZRSBVSPJA-UHFFFAOYSA-N	793657	US20260055079, Example 167	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793657	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793657&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219544	528825120							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729056	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F)N1CCn2nc(C(F)(F)F)cc2C1	InChI=1S/C27H23F4N5O3/c28-22-7-4-15(10-21(22)26(38)35-8-9-36-16(14-35)12-24(34-36)27(29,30)31)11-23-20-13-18(39-17-2-1-3-17)5-6-19(20)25(37)33-32-23/h4-7,10,12-13,17H,1-3,8-9,11,14H2,(H,33,37)	FIWZHILHLNSHBO-UHFFFAOYSA-N	793658	US20260055079, Example 168	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793658	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793658&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220042	528825121							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729057	O=C(c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1Cl)N1CCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C29H26ClF3N6O3/c30-24-7-4-17(13-25-22-14-20(42-19-2-1-3-19)5-6-21(22)26(40)37-36-25)12-23(24)27(41)38-8-10-39(11-9-38)28-34-15-18(16-35-28)29(31,32)33/h4-7,12,14-16,19H,1-3,8-11,13H2,(H,37,40)	CYJGQCBJVAUQQP-UHFFFAOYSA-N	793659	US20260055079, Example 169	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793659	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793659&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219629	528825122							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729058	O=C(c1cccc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)c1)N1CCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C29H27F3N6O3/c30-29(31,32)20-16-33-28(34-17-20)38-11-9-37(10-12-38)27(40)19-4-1-3-18(13-19)14-25-24-15-22(41-21-5-2-6-21)7-8-23(24)26(39)36-35-25/h1,3-4,7-8,13,15-17,21H,2,5-6,9-12,14H2,(H,36,39)	DAHHGEZXVXWVAP-UHFFFAOYSA-N	793660	US20260055079, Example 170	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793660	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793660&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219771	528825123							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729059	O=C(c1cccc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)c1Cl)N1CCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C29H26ClF3N6O3/c30-25-17(13-24-23-14-20(42-19-4-2-5-19)7-8-21(23)26(40)37-36-24)3-1-6-22(25)27(41)38-9-11-39(12-10-38)28-34-15-18(16-35-28)29(31,32)33/h1,3,6-8,14-16,19H,2,4-5,9-13H2,(H,37,40)	HJANZVDNTSFGJM-UHFFFAOYSA-N	793661	US20260055079, Example 171	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793661	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793661&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220119	528825124							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729060	O=C(c1ccc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)cc1F)N1CCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C29H26F4N6O3/c30-24-12-17(13-25-23-14-20(42-19-2-1-3-19)5-7-21(23)26(40)37-36-25)4-6-22(24)27(41)38-8-10-39(11-9-38)28-34-15-18(16-35-28)29(31,32)33/h4-7,12,14-16,19H,1-3,8-11,13H2,(H,37,40)	BYMRWCMVDHPQFJ-UHFFFAOYSA-N	793662	US20260055079, Example 172	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793662	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793662&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219893	528825125							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729061	O=C(c1ccc(Cl)c(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)c1)N1CCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C29H26ClF3N6O3/c30-24-7-4-17(27(41)38-8-10-39(11-9-38)28-34-15-19(16-35-28)29(31,32)33)12-18(24)13-25-23-14-21(42-20-2-1-3-20)5-6-22(23)26(40)37-36-25/h4-7,12,14-16,20H,1-3,8-11,13H2,(H,37,40)	ZFYFZLBTMCKHEY-UHFFFAOYSA-N	793663	US20260055079, Example 173	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793663	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793663&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220015	528825126							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729062	O=C(c1cc(Cl)cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)c1)N1CCN(c2ncc(C(F)(F)F)cn2)CC1	InChI=1S/C29H26ClF3N6O3/c30-20-11-17(12-25-24-14-22(42-21-2-1-3-21)4-5-23(24)26(40)37-36-25)10-18(13-20)27(41)38-6-8-39(9-7-38)28-34-15-19(16-35-28)29(31,32)33/h4-5,10-11,13-16,21H,1-3,6-9,12H2,(H,37,40)	WVUOXKUIZNGPHP-UHFFFAOYSA-N	793664	US20260055079, Example 174	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793664	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793664&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			170167423	528825127							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729063	N#Cc1ccnc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)cc4c3OCC4)CC2)c1	InChI=1S/C32H30N6O4/c33-19-20-6-8-34-29(17-20)37-9-11-38(12-10-37)32(40)27-15-21(14-22-7-13-41-30(22)27)16-28-26-18-24(42-23-2-1-3-23)4-5-25(26)31(39)36-35-28/h4-6,8,14-15,17-18,23H,1-3,7,9-13,16H2,(H,36,39)	HSPPQZOSOMYKTH-UHFFFAOYSA-N	793665	US20260055079, Example 175	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793665	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793665&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219880	528825128							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729064	N#Cc1ccc(N2CCN(C(=O)c3cccc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)n3)CC2)nc1	InChI=1S/C29H27N7O3/c30-17-19-7-10-27(31-18-19)35-11-13-36(14-12-35)29(38)25-6-1-3-20(32-25)15-26-24-16-22(39-21-4-2-5-21)8-9-23(24)28(37)34-33-26/h1,3,6-10,16,18,21H,2,4-5,11-15H2,(H,34,37)	JOOKOPWHAYRZQA-UHFFFAOYSA-N	793666	US20260055079, Example 176	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793666	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793666&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220014	528825129							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729065	N#Cc1ccc(N2CCN(C(=O)c3cccc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)n3)CC2)nc1	InChI=1S/C29H27N7O3/c30-17-19-7-10-27(31-18-19)35-11-13-36(14-12-35)29(38)25-6-1-3-20(32-25)15-26-24-16-22(39-21-4-2-5-21)8-9-23(24)28(37)34-33-26/h1,3,6-10,16,18,21H,2,4-5,11-15H2,(H,34,37)	JOOKOPWHAYRZQA-UHFFFAOYSA-N	793666	US20260055079, Example 176	Poly [ADP-ribose] polymerase 1	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793666	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=232&target=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793666&enzyme=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search			169220014	528825129							1	MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW	9MJA,9MI8,4OQB,4OQA,4OPX,4DQY,8G0H,7S6M,7S6H,5A00,4ZZZ,4XHU,6XVW,5HA9,4PJT,2RCW,1WOK,1UK1,1UK0,6I8T,6I8M,7S81,7S68,6M3I,9DMC,9BPY,8FZ1,8FYZ,8FYY,6NTU,6NRJ,6NRI,6NRH,6NRG,6NRF,6BHV,5DS3,8U4W,2N8A,2RIQ,2JVN,2CR9,2CS2,2L31,2L30,3ODE,3ODC,7SCZ,7SCY,3ODA,3OD8,2DMJ,9UMC,9UMF	Poly [ADP-ribose] polymerase 1	PARP1_HUMAN	P09874	B1ANJ4 Q8IUZ9			N/A	A0A024R3T8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729066	N#Cc1ccc(N2CCN(C(=O)c3cccc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)n3)CC2)nc1	InChI=1S/C29H27N7O3/c30-17-19-7-10-27(31-18-19)35-11-13-36(14-12-35)29(38)25-6-1-3-20(32-25)15-26-24-16-22(39-21-4-2-5-21)8-9-23(24)28(37)34-33-26/h1,3,6-10,16,18,21H,2,4-5,11-15H2,(H,34,37)	JOOKOPWHAYRZQA-UHFFFAOYSA-N	793666	US20260055079, Example 176	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793666	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793666&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220014	528825129							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729067	N#Cc1ccc(N2CCN(C(=O)c3cncc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)c3)CC2)nc1	InChI=1S/C29H27N7O3/c30-15-19-4-7-27(32-17-19)35-8-10-36(11-9-35)29(38)21-12-20(16-31-18-21)13-26-25-14-23(39-22-2-1-3-22)5-6-24(25)28(37)34-33-26/h4-7,12,14,16-18,22H,1-3,8-11,13H2,(H,34,37)	XIYJBOKNMMBZQM-UHFFFAOYSA-N	793667	US20260055079, Example 177	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793667	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793667&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219932	528825130							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729068	N#Cc1ccc(N2CCN(C(=O)c3cncc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)c3)CC2)nc1	InChI=1S/C29H27N7O3/c30-15-19-4-7-27(32-17-19)35-8-10-36(11-9-35)29(38)21-12-20(16-31-18-21)13-26-25-14-23(39-22-2-1-3-22)5-6-24(25)28(37)34-33-26/h4-7,12,14,16-18,22H,1-3,8-11,13H2,(H,34,37)	XIYJBOKNMMBZQM-UHFFFAOYSA-N	793667	US20260055079, Example 177	Poly [ADP-ribose] polymerase 1	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793667	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=232&target=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793667&enzyme=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search			169219932	528825130							1	MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW	9MJA,9MI8,4OQB,4OQA,4OPX,4DQY,8G0H,7S6M,7S6H,5A00,4ZZZ,4XHU,6XVW,5HA9,4PJT,2RCW,1WOK,1UK1,1UK0,6I8T,6I8M,7S81,7S68,6M3I,9DMC,9BPY,8FZ1,8FYZ,8FYY,6NTU,6NRJ,6NRI,6NRH,6NRG,6NRF,6BHV,5DS3,8U4W,2N8A,2RIQ,2JVN,2CR9,2CS2,2L31,2L30,3ODE,3ODC,7SCZ,7SCY,3ODA,3OD8,2DMJ,9UMC,9UMF	Poly [ADP-ribose] polymerase 1	PARP1_HUMAN	P09874	B1ANJ4 Q8IUZ9			N/A	A0A024R3T8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729069	N#Cc1ccc(N2CCN(C(=O)c3cncc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)c3)CC2)nc1	InChI=1S/C29H27N7O3/c30-15-19-4-7-27(32-17-19)35-8-10-36(11-9-35)29(38)21-12-20(16-31-18-21)13-26-25-14-23(39-22-2-1-3-22)5-6-24(25)28(37)34-33-26/h4-7,12,14,16-18,22H,1-3,8-11,13H2,(H,34,37)	XIYJBOKNMMBZQM-UHFFFAOYSA-N	793667	US20260055079, Example 177	Poly [ADP-ribose] polymerase 2	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793667	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793667&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219932	528825130							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729070	N#Cc1ccc(N2CCN(C(=O)c3cc(Br)cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)c3)CC2)nc1	InChI=1S/C30H27BrN6O3/c31-22-13-20(14-27-26-16-24(40-23-2-1-3-23)5-6-25(26)29(38)35-34-27)12-21(15-22)30(39)37-10-8-36(9-11-37)28-7-4-19(17-32)18-33-28/h4-7,12-13,15-16,18,23H,1-3,8-11,14H2,(H,35,38)	HYTIBVGNGWWOOS-UHFFFAOYSA-N	793668	US20260055079, Example 178	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793668&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220296	528825131							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729071	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccn3)CC2)nc1	InChI=1S/C29H27N7O3/c30-17-20-4-7-27(32-18-20)35-10-12-36(13-11-35)29(38)26-15-19(8-9-31-26)14-25-24-16-22(39-21-2-1-3-21)5-6-23(24)28(37)34-33-25/h4-9,15-16,18,21H,1-3,10-14H2,(H,34,37)	UOYODYJMNZJJTQ-UHFFFAOYSA-N	793669	US20260055079, Example 179	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793669	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793669&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220378	528825132							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729072	N#Cc1ccc(N2CCN(C(=O)c3ccnc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)c3)CC2)nc1	InChI=1S/C29H27N7O3/c30-17-19-4-7-27(32-18-19)35-10-12-36(13-11-35)29(38)20-8-9-31-21(14-20)15-26-25-16-23(39-22-2-1-3-22)5-6-24(25)28(37)34-33-26/h4-9,14,16,18,22H,1-3,10-13,15H2,(H,34,37)	PHXLEOXQDYTRNC-UHFFFAOYSA-N	793670	US20260055079, Example 180	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793670	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793670&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219867	528825133							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729073	CN1CCN(C(=O)c2cccc(Cc3n[nH]c(=O)c4ccc(Oc5ccc(C(N)=O)cc5)cc34)c2)CC1	InChI=1S/C28H27N5O4/c1-32-11-13-33(14-12-32)28(36)20-4-2-3-18(15-20)16-25-24-17-22(9-10-23(24)27(35)31-30-25)37-21-7-5-19(6-8-21)26(29)34/h2-10,15,17H,11-14,16H2,1H3,(H2,29,34)(H,31,35)	OLXICCKXXJZFQH-UHFFFAOYSA-N	793671	US20260055079, Example 181	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793671	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793671&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219873	528825134							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729074	COc1ccc2c(=O)[nH]nc(Cc3ccc(S(C)(=O)=O)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C28H26N6O5S/c1-39-20-5-6-21-22(15-20)24(31-32-27(21)35)14-18-3-7-25(40(2,37)38)23(13-18)28(36)34-11-9-33(10-12-34)26-8-4-19(16-29)17-30-26/h3-8,13,15,17H,9-12,14H2,1-2H3,(H,32,35)	WBLPBNMFYGKYPT-UHFFFAOYSA-N	793672	US20260055079, Example 182	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793672	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793672&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219488	528825135							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729075	N#Cc1ccc(N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5ccc(CC(F)(F)F)cc45)ccc3F)CC2)nc1	InChI=1S/C28H22F4N6O2/c29-23-5-2-17(13-24-21-12-18(14-28(30,31)32)1-4-20(21)26(39)36-35-24)11-22(23)27(40)38-9-7-37(8-10-38)25-6-3-19(15-33)16-34-25/h1-6,11-12,16H,7-10,13-14H2,(H,36,39)	XJUYTBIJOHHYOH-UHFFFAOYSA-N	793673	US20260055079, Example 183	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793673	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793673&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219539	528825136							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729076	N#Cc1ccc(N2C[C@H]3C[C@@H]2CN3C(=O)c2cccc(Cc3n[nH]c(=O)c4ccc(-c5cccnc5)cc34)c2)nc1	InChI=1S/C32H25N7O2/c33-15-21-6-9-30(35-16-21)38-18-26-14-25(38)19-39(26)32(41)23-4-1-3-20(11-23)12-29-28-13-22(24-5-2-10-34-17-24)7-8-27(28)31(40)37-36-29/h1-11,13,16-17,25-26H,12,14,18-19H2,(H,37,40)	HRWKIJFFTGLRNK-UHFFFAOYSA-N	793674	US20260055079, Example 184	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793674	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793674&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219479	528825137							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729077	C#CCNc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCn5c(nnc5C(F)(F)F)C4)c3)c2c1	InChI=1S/C25H19F4N7O2/c1-2-7-30-15-4-5-16-17(12-15)20(31-33-22(16)37)11-14-3-6-19(26)18(10-14)23(38)35-8-9-36-21(13-35)32-34-24(36)25(27,28)29/h1,3-6,10,12,30H,7-9,11,13H2,(H,33,37)	LOMRQDVUYOIZRM-UHFFFAOYSA-N	793675	US20260055079, Example 185	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793675	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793675&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219702	528825138							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729078	CN1CCN(C(=O)c2ccc(Cc3n[nH]c(=O)c4c(F)cccc34)cc2)CC1	InChI=1S/C21H21FN4O2/c1-25-9-11-26(12-10-25)21(28)15-7-5-14(6-8-15)13-18-16-3-2-4-17(22)19(16)20(27)24-23-18/h2-8H,9-13H2,1H3,(H,24,27)	WARKOMZKMPSODU-UHFFFAOYSA-N	793676	US20260055079, Example 186	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793676	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793676&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219610	528825139							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729079	CC#Cc1ccc2c(=O)[nH]nc(Oc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)c2c1	InChI=1S/C28H21FN6O3/c1-2-3-18-4-7-21-22(14-18)27(33-32-26(21)36)38-20-6-8-24(29)23(15-20)28(37)35-12-10-34(11-13-35)25-9-5-19(16-30)17-31-25/h4-9,14-15,17H,10-13H2,1H3,(H,32,36)	BYVSPTXOAJJDAR-UHFFFAOYSA-N	793677	6-(4-(2-fluoro-5-(4-oxo-6-(prop-1-ynyl)-3,4-dihydrophthalazin-1-yloxy)benzoyl)piperazin-1-yl)nicotinonitrile and 6-(4-(2-fluoro-5-(4-oxo-7-(prop-1-ynyl)-3,4-dihydrophthalazin-1-yloxy)benzoyl)piperazin-1-yl)nicotinonitrile::US20260055079, Example 187	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793677	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793677&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220154	528825140							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729080	CC#Cc1ccc2c(Oc3ccc(F)c(C(=O)N4CCN(c5ccc(C#N)cn5)CC4)c3)n[nH]c(=O)c2c1	InChI=1S/C28H21FN6O3/c1-2-3-18-4-7-21-22(14-18)26(36)32-33-27(21)38-20-6-8-24(29)23(15-20)28(37)35-12-10-34(11-13-35)25-9-5-19(16-30)17-31-25/h4-9,14-15,17H,10-13H2,1H3,(H,32,36)	HMBJKMMYHHQTFU-UHFFFAOYSA-N	793678	6-(4-(2-fluoro-5-(4-oxo-6-(prop-1-ynyl)-3,4-dihydrophthalazin-1-yloxy)benzoyl)piperazin-1-yl)nicotinonitrile and 6-(4-(2-fluoro-5-(4-oxo-7-(prop-1-ynyl)-3,4-dihydrophthalazin-1-yloxy)benzoyl)piperazin-1-yl)nicotinonitrile::US20260055079, Example 188	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793678	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793678&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219519	528825141							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729081	CN(c1cc(C#N)ccn1)C1CN(S(=O)(=O)c2cc(Cc3n[nH]c(=O)c4ccc(OC5CCC5)cc34)ccc2F)C1	InChI=1S/C29H27FN6O4S/c1-35(28-13-19(15-31)9-10-32-28)20-16-36(17-20)41(38,39)27-12-18(5-8-25(27)30)11-26-24-14-22(40-21-3-2-4-21)6-7-23(24)29(37)34-33-26/h5-10,12-14,20-21H,2-4,11,16-17H2,1H3,(H,34,37)	NAVITRSSCLUIJW-UHFFFAOYSA-N	793679	US20260055079, Example 189	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793679	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793679&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219715	528825142							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729082	N#Cc1ccc(N2CCN(C(=O)c3cc(Oc4n[nH]c(=O)c5ccccc45)ccc3F)CC2)nc1	InChI=1S/C25H19FN6O3/c26-21-7-6-17(35-24-19-4-2-1-3-18(19)23(33)29-30-24)13-20(21)25(34)32-11-9-31(10-12-32)22-8-5-16(14-27)15-28-22/h1-8,13,15H,9-12H2,(H,29,33)	XOIUUPKFOJZJHH-UHFFFAOYSA-N	793680	US20260055079, Example 190	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793680	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793680&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219557	528825143							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729083	CC#Cc1ccc2c(=O)[nH]nc(CNC(C)CC(=O)N3CCN(c4ncc(C(F)(F)F)cn4)CC3)c2c1	InChI=1S/C25H26F3N7O2/c1-3-4-17-5-6-19-20(12-17)21(32-33-23(19)37)15-29-16(2)11-22(36)34-7-9-35(10-8-34)24-30-13-18(14-31-24)25(26,27)28/h5-6,12-14,16,29H,7-11,15H2,1-2H3,(H,33,37)	CVUCVZSNGRCRNU-UHFFFAOYSA-N	793681	US20260055079, Example 191	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793681	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793681&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220313	528825144							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729084	CC#Cc1ccc2c(=O)[nH]nc(CNC(C)CC(=O)N3CCN(c4ncc(C(F)(F)F)cn4)CC3)c2c1	InChI=1S/C25H26F3N7O2/c1-3-4-17-5-6-19-20(12-17)21(32-33-23(19)37)15-29-16(2)11-22(36)34-7-9-35(10-8-34)24-30-13-18(14-31-24)25(26,27)28/h5-6,12-14,16,29H,7-11,15H2,1-2H3,(H,33,37)	CVUCVZSNGRCRNU-UHFFFAOYSA-N	793681	US20260055079, Example 191	Poly [ADP-ribose] polymerase 1	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793681	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=232&target=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793681&enzyme=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search			169220313	528825144							1	MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW	9MJA,9MI8,4OQB,4OQA,4OPX,4DQY,8G0H,7S6M,7S6H,5A00,4ZZZ,4XHU,6XVW,5HA9,4PJT,2RCW,1WOK,1UK1,1UK0,6I8T,6I8M,7S81,7S68,6M3I,9DMC,9BPY,8FZ1,8FYZ,8FYY,6NTU,6NRJ,6NRI,6NRH,6NRG,6NRF,6BHV,5DS3,8U4W,2N8A,2RIQ,2JVN,2CR9,2CS2,2L31,2L30,3ODE,3ODC,7SCZ,7SCY,3ODA,3OD8,2DMJ,9UMC,9UMF	Poly [ADP-ribose] polymerase 1	PARP1_HUMAN	P09874	B1ANJ4 Q8IUZ9			N/A	A0A024R3T8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729085	CC#Cc1ccc2c(=O)[nH]nc(CNC(C)CC(=O)N3CCN(c4ncc(C(F)(F)F)cn4)CC3)c2c1	InChI=1S/C25H26F3N7O2/c1-3-4-17-5-6-19-20(12-17)21(32-33-23(19)37)15-29-16(2)11-22(36)34-7-9-35(10-8-34)24-30-13-18(14-31-24)25(26,27)28/h5-6,12-14,16,29H,7-11,15H2,1-2H3,(H,33,37)	CVUCVZSNGRCRNU-UHFFFAOYSA-N	793681	US20260055079, Example 191	Poly [ADP-ribose] polymerase 2	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793681	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793681&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220313	528825144							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729086	CC#Cc1ccc2c(=O)[nH]nc(C(C)OCCC(=O)N3CCN(c4ncc(C(F)(F)F)cn4)CC3)c2c1	InChI=1S/C25H25F3N6O3/c1-3-4-17-5-6-19-20(13-17)22(31-32-23(19)36)16(2)37-12-7-21(35)33-8-10-34(11-9-33)24-29-14-18(15-30-24)25(26,27)28/h5-6,13-16H,7-12H2,1-2H3,(H,32,36)	XSBFBUMKURKORI-UHFFFAOYSA-N	793682	US20260055079, Example 192	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793682	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793682&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220202	528825145							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729087	CC#Cc1ccc2c(=O)[nH]nc(C(C)N(C)CCC(=O)N3CCN(c4ncc(C(F)(F)F)cn4)CC3)c2c1	InChI=1S/C26H28F3N7O2/c1-4-5-18-6-7-20-21(14-18)23(32-33-24(20)38)17(2)34(3)9-8-22(37)35-10-12-36(13-11-35)25-30-15-19(16-31-25)26(27,28)29/h6-7,14-17H,8-13H2,1-3H3,(H,33,38)	JFGHUGYAMMZBLF-UHFFFAOYSA-N	793683	US20260055079, Example 193	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793683	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793683&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219759	528825146							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729088	CC#Cc1ccc2c(=O)[nH]nc(C(C)N(C)CCC(=O)N3CCN(c4ncc(C(F)(F)F)cn4)CC3)c2c1	InChI=1S/C26H28F3N7O2/c1-4-5-18-6-7-20-21(14-18)23(32-33-24(20)38)17(2)34(3)9-8-22(37)35-10-12-36(13-11-35)25-30-15-19(16-31-25)26(27,28)29/h6-7,14-17H,8-13H2,1-3H3,(H,33,38)	JFGHUGYAMMZBLF-UHFFFAOYSA-N	793683	US20260055079, Example 193	Poly [ADP-ribose] polymerase 2	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793683	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793683&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219759	528825146							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729089	CC#Cc1ccc2c(=O)[nH]nc(C(C)NC(C)CC(=O)N3CCN(c4ncc(C(F)(F)F)cn4)CC3)c2c1	InChI=1S/C26H28F3N7O2/c1-4-5-18-6-7-20-21(13-18)23(33-34-24(20)38)17(3)32-16(2)12-22(37)35-8-10-36(11-9-35)25-30-14-19(15-31-25)26(27,28)29/h6-7,13-17,32H,8-12H2,1-3H3,(H,34,38)	QLFPTGVAIRVIOH-UHFFFAOYSA-N	793684	US20260055079, Example 194	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 75							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793684	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793684&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219970	528825147							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729090	CC#Cc1ccc2c(=O)[nH]nc(C(C)CCCC(=O)N3CCN(c4ncc(C(F)(F)F)cn4)CC3)c2c1	InChI=1S/C26H27F3N6O2/c1-3-5-18-8-9-20-21(14-18)23(32-33-24(20)37)17(2)6-4-7-22(36)34-10-12-35(13-11-34)25-30-15-19(16-31-25)26(27,28)29/h8-9,14-17H,4,6-7,10-13H2,1-2H3,(H,33,37)	PGKVVOJAFHXKNI-UHFFFAOYSA-N	793685	US20260055079, Example 195	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793685	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793685&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220344	528825148							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729091	CC(CC(=O)N1CCN(c2ccc(C#N)cn2)CC1)NCc1n[nH]c(=O)c2ccc(OC3CC3)cc12	InChI=1S/C26H29N7O3/c1-17(12-25(34)33-10-8-32(9-11-33)24-7-2-18(14-27)15-29-24)28-16-23-22-13-20(36-19-3-4-19)5-6-21(22)26(35)31-30-23/h2,5-7,13,15,17,19,28H,3-4,8-12,16H2,1H3,(H,31,35)	TZHGIHPEIBECEK-UHFFFAOYSA-N	793686	US20260055079, Example 196	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793686	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793686&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220079	528825149							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729092	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)NCCN(CC)c4ccc(C#N)cn4)c3)c2c1	InChI=1S/C29H25FN6O2/c1-3-5-19-6-9-22-23(14-19)26(34-35-29(22)38)16-20-7-10-25(30)24(15-20)28(37)32-12-13-36(4-2)27-11-8-21(17-31)18-33-27/h6-11,14-15,18H,4,12-13,16H2,1-2H3,(H,32,37)(H,35,38)	XJLFAZLIPCOWIH-UHFFFAOYSA-N	793687	US20260055079, Example 197	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793687	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793687&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219927	528825150							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729093	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)NCCN(CC)c4ccc(C#N)cn4)c3)c2c1	InChI=1S/C29H25FN6O2/c1-3-5-19-6-9-22-23(14-19)26(34-35-29(22)38)16-20-7-10-25(30)24(15-20)28(37)32-12-13-36(4-2)27-11-8-21(17-31)18-33-27/h6-11,14-15,18H,4,12-13,16H2,1-2H3,(H,32,37)(H,35,38)	XJLFAZLIPCOWIH-UHFFFAOYSA-N	793687	US20260055079, Example 197	Poly [ADP-ribose] polymerase 2	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793687	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793687&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169219927	528825150							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729094	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N(C)CCN(CC)c4ccc(C#N)cn4)c3)c2c1	InChI=1S/C30H27FN6O2/c1-4-6-20-7-10-23-24(15-20)27(34-35-29(23)38)17-21-8-11-26(31)25(16-21)30(39)36(3)13-14-37(5-2)28-12-9-22(18-32)19-33-28/h7-12,15-16,19H,5,13-14,17H2,1-3H3,(H,35,38)	OFUYTSSYLDWJIO-UHFFFAOYSA-N	793688	US20260055079, Example 198	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		<50							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793688	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793688&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220190	528825151							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729095	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N(C)CCN(CC)c4ccc(C#N)cn4)c3)c2c1	InChI=1S/C30H27FN6O2/c1-4-6-20-7-10-23-24(15-20)27(34-35-29(23)38)17-21-8-11-26(31)25(16-21)30(39)36(3)13-14-37(5-2)28-12-9-22(18-32)19-33-28/h7-12,15-16,19H,5,13-14,17H2,1-3H3,(H,35,38)	OFUYTSSYLDWJIO-UHFFFAOYSA-N	793688	US20260055079, Example 198	Poly [ADP-ribose] polymerase 2	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793688	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7439&target=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793688&enzyme=Poly+%5BADP-ribose%5D+polymerase+2&column=ki&startPg=0&Increment=50&submit=Search			169220190	528825151							1	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW	6X0N,6X0M,6X0L,7AEO,9ZQC,9ZQB,4ZZY,4ZZX,6TX3,5DSY,6F5F,6F5B,6F1K,9ZQA,9ZQ9,5D5K	Poly [ADP-ribose] polymerase 2	PARP2_HUMAN	Q9UGN5	Q8TEU4 Q9NUV2 Q9UMR4 Q9Y6C8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729096	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)NCc4nnc(C(F)(F)F)o4)c3)c2c1	InChI=1S/C23H15F4N5O3/c1-2-3-12-4-6-14-15(8-12)18(29-31-21(14)34)10-13-5-7-17(24)16(9-13)20(33)28-11-19-30-32-22(35-19)23(25,26)27/h4-9H,10-11H2,1H3,(H,28,33)(H,31,34)	ZYRGDXOILSOJAR-UHFFFAOYSA-N	793689	US20260055079, Example 199	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793689	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793689&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220072	528825152							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729097	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)NC(C)c4nnc(C(F)(F)F)o4)c3)c2c1	InChI=1S/C24H17F4N5O3/c1-3-4-13-5-7-15-16(9-13)19(30-31-21(15)35)11-14-6-8-18(25)17(10-14)20(34)29-12(2)22-32-33-23(36-22)24(26,27)28/h5-10,12H,11H2,1-2H3,(H,29,34)(H,31,35)	DSULATOUHXZGLP-UHFFFAOYSA-N	793690	US20260055079, Example 200	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793690	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793690&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219502	528825153							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729098	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N(C)C4CN(c5ccc(C#N)cn5)C4)c3)c2c1	InChI=1S/C29H23FN6O2/c1-3-4-18-5-8-22-23(11-18)26(33-34-28(22)37)13-19-6-9-25(30)24(12-19)29(38)35(2)21-16-36(17-21)27-10-7-20(14-31)15-32-27/h5-12,15,21H,13,16-17H2,1-2H3,(H,34,37)	YZFTWGDJTRFUNL-UHFFFAOYSA-N	793691	US20260055079, Example 201	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793691	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793691&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219944	528825154							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729099	CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N(C)Cc4nnc(C(F)(F)F)o4)c3)c2c1	InChI=1S/C24H17F4N5O3/c1-3-4-13-5-7-15-16(9-13)19(29-31-21(15)34)11-14-6-8-18(25)17(10-14)22(35)33(2)12-20-30-32-23(36-20)24(26,27)28/h5-10H,11-12H2,1-2H3,(H,31,34)	QWNONCWDJJZHFU-UHFFFAOYSA-N	793692	US20260055079, Example 202	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793692	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793692&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220330	528825155							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729100	O=C(NC1CN(C(=O)C2CC2)C1)c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F	InChI=1S/C27H27FN4O4/c28-23-9-4-15(10-22(23)25(33)29-17-13-32(14-17)27(35)16-5-6-16)11-24-21-12-19(36-18-2-1-3-18)7-8-20(21)26(34)31-30-24/h4,7-10,12,16-18H,1-3,5-6,11,13-14H2,(H,29,33)(H,31,34)	UTYBZTUSZDXNAL-UHFFFAOYSA-N	793693	US20260055079, Example 203	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793693	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793693&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220012	528825156							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729101	N#Cc1ccc(N2CC(NC(=O)c3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc3F)C2)nc1	InChI=1S/C29H25FN6O3/c30-25-8-4-17(10-24(25)28(37)33-19-15-36(16-19)27-9-5-18(13-31)14-32-27)11-26-23-12-21(39-20-2-1-3-20)6-7-22(23)29(38)35-34-26/h4-10,12,14,19-20H,1-3,11,15-16H2,(H,33,37)(H,35,38)	ZDSINLRSIYLUIV-UHFFFAOYSA-N	793694	US20260055079, Example 204	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793694	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793694&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220050	528825157							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729102	O=C(NC1CN(c2ncc(C(F)(F)F)cn2)C1)c1cc(Cc2n[nH]c(=O)c3ccc(OC4CCC4)cc23)ccc1F	InChI=1S/C28H24F4N6O3/c29-23-7-4-15(9-24-21-10-19(41-18-2-1-3-18)5-6-20(21)26(40)37-36-24)8-22(23)25(39)35-17-13-38(14-17)27-33-11-16(12-34-27)28(30,31)32/h4-8,10-12,17-18H,1-3,9,13-14H2,(H,35,39)(H,37,40)	QKQDAECUARYIPI-UHFFFAOYSA-N	793695	US20260055079, Example 205	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793695	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793695&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219697	528825158							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729103	O=C(C1CC1)N1CCN(c2noc3c(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)cccc23)CC1	InChI=1S/C28H29N5O4/c34-27-21-10-9-20(36-19-4-2-5-19)16-23(21)24(29-30-27)15-18-3-1-6-22-25(18)37-31-26(22)32-11-13-33(14-12-32)28(35)17-7-8-17/h1,3,6,9-10,16-17,19H,2,4-5,7-8,11-15H2,(H,30,34)	AVJJOOSDDFQFGV-UHFFFAOYSA-N	793696	US20260055079, Example 206	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793696	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793696&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219603	528825159							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729104	O=c1[nH]nc(Cc2cccc3c(N4CCN(c5ncc(C(F)(F)F)cn5)CC4)noc23)c2cc(OC3CCC3)ccc12	InChI=1S/C29H26F3N7O3/c30-29(31,32)18-15-33-28(34-16-18)39-11-9-38(10-12-39)26-22-6-1-3-17(25(22)42-37-26)13-24-23-14-20(41-19-4-2-5-19)7-8-21(23)27(40)36-35-24/h1,3,6-8,14-16,19H,2,4-5,9-13H2,(H,36,40)	PCFQXESBDYQAQQ-UHFFFAOYSA-N	793697	US20260055079, Example 207	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793697	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793697&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219724	528825160							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729105	N#Cc1ccc(N2CCN(c3noc4c(Cc5n[nH]c(=O)c6ccc(OC7CCC7)cc56)cccc34)CC2)nc1	InChI=1S/C30H27N7O3/c31-17-19-7-10-27(32-18-19)36-11-13-37(14-12-36)29-24-6-1-3-20(28(24)40-35-29)15-26-25-16-22(39-21-4-2-5-21)8-9-23(25)30(38)34-33-26/h1,3,6-10,16,18,21H,2,4-5,11-15H2,(H,34,38)	JZNRVOMWRZGDKK-UHFFFAOYSA-N	793698	US20260055079, Example 208	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793698	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793698&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220040	528825161							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729106	O=c1[nH]nc(Cc2ccc3onc(N4CCN(c5ncc(C(F)(F)F)cn5)CC4)c3c2)c2cc(OC3CCC3)ccc12	InChI=1S/C29H26F3N7O3/c30-29(31,32)18-15-33-28(34-16-18)39-10-8-38(9-11-39)26-23-12-17(4-7-25(23)42-37-26)13-24-22-14-20(41-19-2-1-3-19)5-6-21(22)27(40)36-35-24/h4-7,12,14-16,19H,1-3,8-11,13H2,(H,36,40)	FODCFWPTERXBMW-UHFFFAOYSA-N	793699	US20260055079, Example 209	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793699	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793699&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219752	528825162							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729107	O=C(C1CC1)N1CCN(c2noc3ccc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)cc23)CC1	InChI=1S/C28H29N5O4/c34-27-21-8-7-20(36-19-2-1-3-19)16-22(21)24(29-30-27)15-17-4-9-25-23(14-17)26(31-37-25)32-10-12-33(13-11-32)28(35)18-5-6-18/h4,7-9,14,16,18-19H,1-3,5-6,10-13,15H2,(H,30,34)	YISUOLIXLXRWKF-UHFFFAOYSA-N	793700	US20260055079, Example 210	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 1250							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793700	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793700&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220254	528825163							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729108	N#Cc1ccc(N2CCN(c3noc4ccc(Cc5n[nH]c(=O)c6ccc(OC7CCC7)cc56)cc34)CC2)nc1	InChI=1S/C30H27N7O3/c31-17-20-5-9-28(32-18-20)36-10-12-37(13-11-36)29-25-14-19(4-8-27(25)40-35-29)15-26-24-16-22(39-21-2-1-3-21)6-7-23(24)30(38)34-33-26/h4-9,14,16,18,21H,1-3,10-13,15H2,(H,34,38)	INGUNRCJMDYZAW-UHFFFAOYSA-N	793701	US20260055079, Example 211	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		 300							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793701	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793701&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219574	528825164							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729109	O=c1[nH]nc(Cc2ccc3c(N4CCN(c5ncc(C(F)(F)F)cn5)CC4)noc3c2)c2cc(OC3CCC3)ccc12	InChI=1S/C29H26F3N7O3/c30-29(31,32)18-15-33-28(34-16-18)39-10-8-38(9-11-39)26-22-6-4-17(13-25(22)42-37-26)12-24-23-14-20(41-19-2-1-3-19)5-7-21(23)27(40)36-35-24/h4-7,13-16,19H,1-3,8-12H2,(H,36,40)	IXCLHAIMTSWJEP-UHFFFAOYSA-N	793702	US20260055079, Example 212	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793702	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793702&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219727	528825165							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729110	O=C(C1CC1)N1CCN(c2noc3cc(Cc4n[nH]c(=O)c5ccc(OC6CCC6)cc45)ccc23)CC1	InChI=1S/C28H29N5O4/c34-27-21-9-7-20(36-19-2-1-3-19)16-23(21)24(29-30-27)14-17-4-8-22-25(15-17)37-31-26(22)32-10-12-33(13-11-32)28(35)18-5-6-18/h4,7-9,15-16,18-19H,1-3,5-6,10-14H2,(H,30,34)	ZLYWEVKPDRVQHE-UHFFFAOYSA-N	793703	US20260055079, Example 213	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793703	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793703&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169219866	528825166							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729111	N#Cc1ccc(N2CCN(c3noc4cc(Cc5n[nH]c(=O)c6ccc(OC7CCC7)cc56)ccc34)CC2)nc1	InChI=1S/C30H27N7O3/c31-17-20-5-9-28(32-18-20)36-10-12-37(13-11-36)29-24-7-4-19(15-27(24)40-35-29)14-26-25-16-22(39-21-2-1-3-21)6-8-23(25)30(38)34-33-26/h4-9,15-16,18,21H,1-3,10-14H2,(H,34,38)	MKUVTGHDELEOTI-UHFFFAOYSA-N	793704	US20260055079, Example 214	Protein mono-ADP-ribosyltransferase TIPARP	Homo sapiens		>2000							US Patent		10.7270/Q27D313T		aid1798066	US20260055079	JOHNSON, MG; SPELLMEYER, DC; NG, RA; LAPOINTE, D; DENG, JN; COHEN, MS; RODRIGUEZ, KM; SUNDALAM, SK; SANDERSON, DJ; PELLETIER, G; WINTER, DK; NOVOSELTSEVA, P; ZHOU, Y	2/26/2026	7/8/2026	Azkarra Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793704	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=697&target=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793704&enzyme=Protein+mono-ADP-ribosyltransferase+TIPARP&column=ki&startPg=0&Increment=50&submit=Search			169220303	528825167							1	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI		Protein mono-ADP-ribosyltransferase TIPARP	PARPT_HUMAN	Q7Z3E1	D3DNK6 Q68CY9 Q86VP4 Q9Y4P7