BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
729206	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C24H19F3N6O2/c1-31-21-12-28-10-17(18(21)11-30-31)15-6-8-16(9-7-15)33-20-5-3-2-4-19(20)32(23(33)35)13-22(34)29-14-24(25,26)27/h2-12H,13-14H2,1H3,(H,29,34)	OPNRADQZBSMRIE-UHFFFAOYSA-N	793733	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 1	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793733	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793733&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960344	528825196							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729207	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C24H19F3N6O2/c1-31-21-12-28-10-17(18(21)11-30-31)15-6-8-16(9-7-15)33-20-5-3-2-4-19(20)32(23(33)35)13-22(34)29-14-24(25,26)27/h2-12H,13-14H2,1H3,(H,29,34)	OPNRADQZBSMRIE-UHFFFAOYSA-N	793733	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 1	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793733	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793733&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960344	528825196							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729208	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCC[C@H]5C(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C27H23F3N6O2/c1-33-23-15-31-13-19(20(23)14-32-33)17-8-10-18(11-9-17)36-22-6-3-2-5-21(22)35(26(36)38)16-25(37)34-12-4-7-24(34)27(28,29)30/h2-3,5-6,8-11,13-15,24H,4,7,12,16H2,1H3	SXTAQGDRXUMPMC-UHFFFAOYSA-N	793734	1-[4-(1-methylpyrazolo[3,4-c]-pyridin-4-yl)phenyl]-3-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 2	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793734	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793734&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			174195678	528825197							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729209	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCC[C@H]5C(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C27H23F3N6O2/c1-33-23-15-31-13-19(20(23)14-32-33)17-8-10-18(11-9-17)36-22-6-3-2-5-21(22)35(26(36)38)16-25(37)34-12-4-7-24(34)27(28,29)30/h2-3,5-6,8-11,13-15,24H,4,7,12,16H2,1H3	SXTAQGDRXUMPMC-UHFFFAOYSA-N	793734	1-[4-(1-methylpyrazolo[3,4-c]-pyridin-4-yl)phenyl]-3-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 2	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793734	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793734&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			174195678	528825197							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729210	C[C@H](NC(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21)C(F)(F)F	InChI=1S/C25H21F3N6O2/c1-15(25(26,27)28)31-23(35)14-33-20-5-3-4-6-21(20)34(24(33)36)17-9-7-16(8-10-17)18-11-29-13-22-19(18)12-30-32(22)2/h3-13,15H,14H2,1-2H3,(H,31,35)	GLGSHGLDCDONCN-UHFFFAOYSA-N	793735	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methylethyl]acetamide::US20260055102, Example 3	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793735	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793735&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960309	528825198							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729211	C[C@H](NC(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21)C(F)(F)F	InChI=1S/C25H21F3N6O2/c1-15(25(26,27)28)31-23(35)14-33-20-5-3-4-6-21(20)34(24(33)36)17-9-7-16(8-10-17)18-11-29-13-22-19(18)12-30-32(22)2/h3-13,15H,14H2,1-2H3,(H,31,35)	GLGSHGLDCDONCN-UHFFFAOYSA-N	793735	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methylethyl]acetamide::US20260055102, Example 3	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793735	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793735&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960309	528825198							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729212	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)cc3F)cncc21	InChI=1S/C24H18F4N6O2/c1-32-21-11-29-9-16(17(21)10-31-32)15-7-6-14(8-18(15)25)34-20-5-3-2-4-19(20)33(23(34)36)12-22(35)30-13-24(26,27)28/h2-11H,12-13H2,1H3,(H,30,35)	WPUDIJQQYJVSGV-UHFFFAOYSA-N	793736	2-[3-[3-fluoro-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 4	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793736	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793736&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960231	528825199							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729213	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)cc3F)cncc21	InChI=1S/C24H18F4N6O2/c1-32-21-11-29-9-16(17(21)10-31-32)15-7-6-14(8-18(15)25)34-20-5-3-2-4-19(20)33(23(34)36)12-22(35)30-13-24(26,27)28/h2-11H,12-13H2,1H3,(H,30,35)	WPUDIJQQYJVSGV-UHFFFAOYSA-N	793736	2-[3-[3-fluoro-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 4	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793736	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793736&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960231	528825199							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729214	Cc1cc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3ccccc32)ccc1-c1cncc2c1cnn2C	InChI=1S/C25H21F3N6O2/c1-15-9-16(7-8-17(15)18-10-29-12-22-19(18)11-31-32(22)2)34-21-6-4-3-5-20(21)33(24(34)36)13-23(35)30-14-25(26,27)28/h3-12H,13-14H2,1-2H3,(H,30,35)	HXTWYUTXGRWYKS-UHFFFAOYSA-N	793737	2-[3-[3-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 5	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793737	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793737&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960216	528825200							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729215	Cc1cc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3ccccc32)ccc1-c1cncc2c1cnn2C	InChI=1S/C25H21F3N6O2/c1-15-9-16(7-8-17(15)18-10-29-12-22-19(18)11-31-32(22)2)34-21-6-4-3-5-20(21)33(24(34)36)13-23(35)30-14-25(26,27)28/h3-12H,13-14H2,1-2H3,(H,30,35)	HXTWYUTXGRWYKS-UHFFFAOYSA-N	793737	2-[3-[3-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 5	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793737	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793737&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960216	528825200							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729216	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C25H21F3N6O2/c1-15-4-3-5-20-23(15)34(24(36)33(20)13-22(35)30-14-25(26,27)28)17-8-6-16(7-9-17)18-10-29-12-21-19(18)11-31-32(21)2/h3-12H,13-14H2,1-2H3,(H,30,35)	PMVOOUIFBCDKIG-UHFFFAOYSA-N	793738	2-[4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 6	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793738	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793738&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960409	528825201							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729217	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C25H21F3N6O2/c1-15-4-3-5-20-23(15)34(24(36)33(20)13-22(35)30-14-25(26,27)28)17-8-6-16(7-9-17)18-10-29-12-21-19(18)11-31-32(21)2/h3-12H,13-14H2,1-2H3,(H,30,35)	PMVOOUIFBCDKIG-UHFFFAOYSA-N	793738	2-[4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 6	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793738	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793738&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960409	528825201							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729218	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C26H23F3N6O2/c1-15-5-4-6-21-24(15)35(25(37)34(21)14-23(36)32-16(2)26(27,28)29)18-9-7-17(8-10-18)19-11-30-13-22-20(19)12-31-33(22)3/h4-13,16H,14H2,1-3H3,(H,32,36)	MQNYPYBEYSMRFS-UHFFFAOYSA-N	793739	2-[4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methylethyl]acetamide::US20260055102, Example 7	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793739	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793739&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960417	528825202							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729219	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C26H23F3N6O2/c1-15-5-4-6-21-24(15)35(25(37)34(21)14-23(36)32-16(2)26(27,28)29)18-9-7-17(8-10-18)19-11-30-13-22-20(19)12-31-33(22)3/h4-13,16H,14H2,1-3H3,(H,32,36)	MQNYPYBEYSMRFS-UHFFFAOYSA-N	793739	2-[4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methylethyl]acetamide::US20260055102, Example 7	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793739	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793739&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960417	528825202							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729220	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCC[C@H]1C(F)(F)F	InChI=1S/C28H25F3N6O2/c1-17-5-3-6-22-26(17)37(27(39)36(22)16-25(38)35-12-4-7-24(35)28(29,30)31)19-10-8-18(9-11-19)20-13-32-15-23-21(20)14-33-34(23)2/h3,5-6,8-11,13-15,24H,4,7,12,16H2,1-2H3	OAUNKWBAKOIKCQ-UHFFFAOYSA-N	793740	4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 8	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793740	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793740&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			174195679	528825203							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729221	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCC[C@H]1C(F)(F)F	InChI=1S/C28H25F3N6O2/c1-17-5-3-6-22-26(17)37(27(39)36(22)16-25(38)35-12-4-7-24(35)28(29,30)31)19-10-8-18(9-11-19)20-13-32-15-23-21(20)14-33-34(23)2/h3,5-6,8-11,13-15,24H,4,7,12,16H2,1-2H3	OAUNKWBAKOIKCQ-UHFFFAOYSA-N	793740	4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 8	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793740	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793740&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			174195679	528825203							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729222	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCOC(C(F)(F)F)C1	InChI=1S/C28H25F3N6O3/c1-17-4-3-5-22-26(17)37(27(39)36(22)16-25(38)35-10-11-40-24(15-35)28(29,30)31)19-8-6-18(7-9-19)20-12-32-14-23-21(20)13-33-34(23)2/h3-9,12-14,24H,10-11,15-16H2,1-2H3	HJWCMDQMYPLKKY-UHFFFAOYSA-N	793741	4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[2-(trifluoromethyl)-morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 9	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793741	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793741&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960381	528825204							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729223	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCOC(C(F)(F)F)C1	InChI=1S/C28H25F3N6O3/c1-17-4-3-5-22-26(17)37(27(39)36(22)16-25(38)35-10-11-40-24(15-35)28(29,30)31)19-8-6-18(7-9-19)20-12-32-14-23-21(20)13-33-34(23)2/h3-9,12-14,24H,10-11,15-16H2,1-2H3	HJWCMDQMYPLKKY-UHFFFAOYSA-N	793741	4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[2-(trifluoromethyl)-morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 9	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793741	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793741&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960381	528825204							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729224	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCO[C@@H](C(F)(F)F)C1	InChI=1S/C28H25F3N6O3/c1-17-4-3-5-22-26(17)37(27(39)36(22)16-25(38)35-10-11-40-24(15-35)28(29,30)31)19-8-6-18(7-9-19)20-12-32-14-23-21(20)13-33-34(23)2/h3-9,12-14,24H,10-11,15-16H2,1-2H3	HJWCMDQMYPLKKY-UHFFFAOYSA-N	793742	4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[(2R)-2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 10	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793742	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793742&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960389	528825205							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729225	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCO[C@@H](C(F)(F)F)C1	InChI=1S/C28H25F3N6O3/c1-17-4-3-5-22-26(17)37(27(39)36(22)16-25(38)35-10-11-40-24(15-35)28(29,30)31)19-8-6-18(7-9-19)20-12-32-14-23-21(20)13-33-34(23)2/h3-9,12-14,24H,10-11,15-16H2,1-2H3	HJWCMDQMYPLKKY-UHFFFAOYSA-N	793742	4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[(2R)-2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 10	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793742	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793742&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960389	528825205							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729226	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5cccc(Cl)c54)cc3)cncc21	InChI=1S/C24H18ClF3N6O2/c1-32-20-11-29-9-16(17(20)10-31-32)14-5-7-15(8-6-14)34-22-18(25)3-2-4-19(22)33(23(34)36)12-21(35)30-13-24(26,27)28/h2-11H,12-13H2,1H3,(H,30,35)	SQORPRJTMQAFSS-UHFFFAOYSA-N	793743	2-[4-chloro-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 11	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793743	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793743&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960288	528825206							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729227	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5cccc(Cl)c54)cc3)cncc21	InChI=1S/C24H18ClF3N6O2/c1-32-20-11-29-9-16(17(20)10-31-32)14-5-7-15(8-6-14)34-22-18(25)3-2-4-19(22)33(23(34)36)12-21(35)30-13-24(26,27)28/h2-11H,12-13H2,1H3,(H,30,35)	SQORPRJTMQAFSS-UHFFFAOYSA-N	793743	2-[4-chloro-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 11	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793743	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793743&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960288	528825206							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729228	COc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C25H21F3N6O3/c1-32-20-12-29-10-17(18(20)11-31-32)15-6-8-16(9-7-15)34-23-19(4-3-5-21(23)37-2)33(24(34)36)13-22(35)30-14-25(26,27)28/h3-12H,13-14H2,1-2H3,(H,30,35)	SAPUUAPWXDDPLR-UHFFFAOYSA-N	793744	2-[4-methoxy-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 12	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793744	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793744&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960341	528825207							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729229	COc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C25H21F3N6O3/c1-32-20-12-29-10-17(18(20)11-31-32)15-6-8-16(9-7-15)34-23-19(4-3-5-21(23)37-2)33(24(34)36)13-22(35)30-14-25(26,27)28/h3-12H,13-14H2,1-2H3,(H,30,35)	SAPUUAPWXDDPLR-UHFFFAOYSA-N	793744	2-[4-methoxy-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 12	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793744	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793744&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960341	528825207							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729230	Cc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2ccccc21	InChI=1S/C25H21F3N6O2/c1-15-9-16(17-10-29-12-22-18(17)11-31-32(22)2)7-8-19(15)34-21-6-4-3-5-20(21)33(24(34)36)13-23(35)30-14-25(26,27)28/h3-12H,13-14H2,1-2H3,(H,30,35)	RFJGQFUJTOMAJM-UHFFFAOYSA-N	793745	2-[3-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 13	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793745	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793745&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960483	528825208							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729231	Cc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2ccccc21	InChI=1S/C25H21F3N6O2/c1-15-9-16(17-10-29-12-22-18(17)11-31-32(22)2)7-8-19(15)34-21-6-4-3-5-20(21)33(24(34)36)13-23(35)30-14-25(26,27)28/h3-12H,13-14H2,1-2H3,(H,30,35)	RFJGQFUJTOMAJM-UHFFFAOYSA-N	793745	2-[3-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 13	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793745	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793745&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960483	528825208							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729232	Cc1cc(-c2cncc3[nH]ncc23)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2ccccc21	InChI=1S/C24H19F3N6O2/c1-14-8-15(16-9-28-11-18-17(16)10-30-31-18)6-7-19(14)33-21-5-3-2-4-20(21)32(23(33)35)12-22(34)29-13-24(25,26)27/h2-11H,12-13H2,1H3,(H,29,34)(H,30,31)	NZQYISHQMSTKBZ-UHFFFAOYSA-N	793746	2-[3-[2-methyl-4-(1H-pyrazolo-[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 14	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793746	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793746&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960321	528825209							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729233	Cc1cc(-c2cncc3[nH]ncc23)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2ccccc21	InChI=1S/C24H19F3N6O2/c1-14-8-15(16-9-28-11-18-17(16)10-30-31-18)6-7-19(14)33-21-5-3-2-4-20(21)32(23(33)35)12-22(34)29-13-24(25,26)27/h2-11H,12-13H2,1H3,(H,29,34)(H,30,31)	NZQYISHQMSTKBZ-UHFFFAOYSA-N	793746	2-[3-[2-methyl-4-(1H-pyrazolo-[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 14	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793746	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793746&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960321	528825209							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729234	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)c(F)c3)cncc21	InChI=1S/C24H18F4N6O2/c1-32-21-11-29-9-15(16(21)10-31-32)14-6-7-18(17(25)8-14)34-20-5-3-2-4-19(20)33(23(34)36)12-22(35)30-13-24(26,27)28/h2-11H,12-13H2,1H3,(H,30,35)	RIEPXSGBCXOPNA-UHFFFAOYSA-N	793747	2-[3-[2-fluoro-4-(1-methyl-pyrazolo[3,4-c]pyridin-4-yl)-phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)-acetamide::US20260055102, Example 15	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793747	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793747&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960329	528825210							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729235	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)c(F)c3)cncc21	InChI=1S/C24H18F4N6O2/c1-32-21-11-29-9-15(16(21)10-31-32)14-6-7-18(17(25)8-14)34-20-5-3-2-4-19(20)33(23(34)36)12-22(35)30-13-24(26,27)28/h2-11H,12-13H2,1H3,(H,30,35)	RIEPXSGBCXOPNA-UHFFFAOYSA-N	793747	2-[3-[2-fluoro-4-(1-methyl-pyrazolo[3,4-c]pyridin-4-yl)-phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)-acetamide::US20260055102, Example 15	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793747	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793747&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960329	528825210							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729236	Cc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C26H23F3N6O2/c1-15-5-4-6-21-24(15)35(25(37)34(21)13-23(36)31-14-26(27,28)29)20-8-7-17(9-16(20)2)18-10-30-12-22-19(18)11-32-33(22)3/h4-12H,13-14H2,1-3H3,(H,31,36)	JNMCPTGTZHNOCC-UHFFFAOYSA-N	793748	2-[4-methyl-3-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)-acetamide::US20260055102, Example 16	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793748	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793748&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960217	528825211							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729237	Cc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C26H23F3N6O2/c1-15-5-4-6-21-24(15)35(25(37)34(21)13-23(36)31-14-26(27,28)29)20-8-7-17(9-16(20)2)18-10-30-12-22-19(18)11-32-33(22)3/h4-12H,13-14H2,1-3H3,(H,31,36)	JNMCPTGTZHNOCC-UHFFFAOYSA-N	793748	2-[4-methyl-3-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)-acetamide::US20260055102, Example 16	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793748	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793748&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960217	528825211							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729238	CC(NC(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21)C(F)(F)F	InChI=1S/C25H21F3N6O2/c1-15(25(26,27)28)31-23(35)14-33-20-5-3-4-6-21(20)34(24(33)36)17-9-7-16(8-10-17)18-11-29-13-22-19(18)12-30-32(22)2/h3-13,15H,14H2,1-2H3,(H,31,35)	GLGSHGLDCDONCN-UHFFFAOYSA-N	793754	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoro-1-methylethyl)acetamide::US20260055102, Example 17	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793754	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793754&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960257	528825217							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729239	CC(NC(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21)C(F)(F)F	InChI=1S/C25H21F3N6O2/c1-15(25(26,27)28)31-23(35)14-33-20-5-3-4-6-21(20)34(24(33)36)17-9-7-16(8-10-17)18-11-29-13-22-19(18)12-30-32(22)2/h3-13,15H,14H2,1-2H3,(H,31,35)	GLGSHGLDCDONCN-UHFFFAOYSA-N	793754	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(2,2,2-trifluoro-1-methylethyl)acetamide::US20260055102, Example 17	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793754	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793754&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960257	528825217							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729240	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCCC5C(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C27H23F3N6O2/c1-33-23-15-31-13-19(20(23)14-32-33)17-8-10-18(11-9-17)36-22-6-3-2-5-21(22)35(26(36)38)16-25(37)34-12-4-7-24(34)27(28,29)30/h2-3,5-6,8-11,13-15,24H,4,7,12,16H2,1H3	SXTAQGDRXUMPMC-UHFFFAOYSA-N	793755	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 18	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793755	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793755&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960242	528825218							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729241	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCCC5C(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C27H23F3N6O2/c1-33-23-15-31-13-19(20(23)14-32-33)17-8-10-18(11-9-17)36-22-6-3-2-5-21(22)35(26(36)38)16-25(37)34-12-4-7-24(34)27(28,29)30/h2-3,5-6,8-11,13-15,24H,4,7,12,16H2,1H3	SXTAQGDRXUMPMC-UHFFFAOYSA-N	793755	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 18	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793755	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793755&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960242	528825218							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729242	CC(NC(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21)C1CC1	InChI=1S/C27H26N6O2/c1-17(18-7-8-18)30-26(34)16-32-23-5-3-4-6-24(23)33(27(32)35)20-11-9-19(10-12-20)21-13-28-15-25-22(21)14-29-31(25)2/h3-6,9-15,17-18H,7-8,16H2,1-2H3,(H,30,34)	KQHGKSAKPKIOLI-UHFFFAOYSA-N	793756	N-(1-cyclopropylethyl)-2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]acetamide::US20260055102, Example 19	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793756	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793756&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960220	528825219							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729243	CC(NC(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21)C1CC1	InChI=1S/C27H26N6O2/c1-17(18-7-8-18)30-26(34)16-32-23-5-3-4-6-24(23)33(27(32)35)20-11-9-19(10-12-20)21-13-28-15-25-22(21)14-29-31(25)2/h3-6,9-15,17-18H,7-8,16H2,1-2H3,(H,30,34)	KQHGKSAKPKIOLI-UHFFFAOYSA-N	793756	N-(1-cyclopropylethyl)-2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]acetamide::US20260055102, Example 19	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793756	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793756&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960220	528825219							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729244	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCCCC5C(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C28H25F3N6O2/c1-34-24-16-32-14-20(21(24)15-33-34)18-9-11-19(12-10-18)37-23-7-3-2-6-22(23)36(27(37)39)17-26(38)35-13-5-4-8-25(35)28(29,30)31/h2-3,6-7,9-12,14-16,25H,4-5,8,13,17H2,1H3	BFGORKDMHLKZCM-UHFFFAOYSA-N	793757	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[2-(trifluoromethyl)-1-piperidyl]ethyl]benzimidazol-2-one::US20260055102, Example 20	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793757	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793757&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960250	528825220							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729245	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCCCC5C(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C28H25F3N6O2/c1-34-24-16-32-14-20(21(24)15-33-34)18-9-11-19(12-10-18)37-23-7-3-2-6-22(23)36(27(37)39)17-26(38)35-13-5-4-8-25(35)28(29,30)31/h2-3,6-7,9-12,14-16,25H,4-5,8,13,17H2,1H3	BFGORKDMHLKZCM-UHFFFAOYSA-N	793757	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[2-(trifluoromethyl)-1-piperidyl]ethyl]benzimidazol-2-one::US20260055102, Example 20	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793757	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793757&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960250	528825220							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729246	CN1CCN(C(=O)Cn2c(=O)n(-c3ccc(-c4cncc5c4cnn5C)cc3)c3ccccc32)CC1	InChI=1S/C27H27N7O2/c1-30-11-13-32(14-12-30)26(35)18-33-23-5-3-4-6-24(23)34(27(33)36)20-9-7-19(8-10-20)21-15-28-17-25-22(21)16-29-31(25)2/h3-10,15-17H,11-14,18H2,1-2H3	AFHIFSNRQGPWNI-UHFFFAOYSA-N	793758	1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-3-[4-(1-methyl-pyrazolo[3,4-c]pyridin-4-yl)phenyl]benzimidazol-2-one::US20260055102, Example 21	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793758	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793758&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960169	528825221							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729247	CN1CCN(C(=O)Cn2c(=O)n(-c3ccc(-c4cncc5c4cnn5C)cc3)c3ccccc32)CC1	InChI=1S/C27H27N7O2/c1-30-11-13-32(14-12-30)26(35)18-33-23-5-3-4-6-24(23)34(27(33)36)20-9-7-19(8-10-20)21-15-28-17-25-22(21)16-29-31(25)2/h3-10,15-17H,11-14,18H2,1-2H3	AFHIFSNRQGPWNI-UHFFFAOYSA-N	793758	1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-3-[4-(1-methyl-pyrazolo[3,4-c]pyridin-4-yl)phenyl]benzimidazol-2-one::US20260055102, Example 21	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793758	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793758&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960169	528825221							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729248	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCOCC5)c5ccccc54)cc3)cncc21	InChI=1S/C26H24N6O3/c1-29-24-16-27-14-20(21(24)15-28-29)18-6-8-19(9-7-18)32-23-5-3-2-4-22(23)31(26(32)34)17-25(33)30-10-12-35-13-11-30/h2-9,14-16H,10-13,17H2,1H3	RTJKHAFPFLFALF-UHFFFAOYSA-N	793759	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-(2-morpholino-2-oxoethyl)-benzimidazol-2-one::US20260055102, Example 22	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793759	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793759&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960376	528825222							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729249	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCOCC5)c5ccccc54)cc3)cncc21	InChI=1S/C26H24N6O3/c1-29-24-16-27-14-20(21(24)15-28-29)18-6-8-19(9-7-18)32-23-5-3-2-4-22(23)31(26(32)34)17-25(33)30-10-12-35-13-11-30/h2-9,14-16H,10-13,17H2,1H3	RTJKHAFPFLFALF-UHFFFAOYSA-N	793759	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-(2-morpholino-2-oxoethyl)-benzimidazol-2-one::US20260055102, Example 22	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793759	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793759&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960376	528825222							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729250	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCCC(C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C28H25F3N6O2/c1-34-25-15-32-13-21(22(25)14-33-34)18-8-10-20(11-9-18)37-24-7-3-2-6-23(24)36(27(37)39)17-26(38)35-12-4-5-19(16-35)28(29,30)31/h2-3,6-11,13-15,19H,4-5,12,16-17H2,1H3	CDRONGCKHQNJSS-UHFFFAOYSA-N	793760	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[3-(trifluoromethyl)-1-piperidyl]ethyl]benzimidazol-2-one::US20260055102, Example 23	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793760	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793760&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960223	528825223							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729251	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCCC(C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C28H25F3N6O2/c1-34-25-15-32-13-21(22(25)14-33-34)18-8-10-20(11-9-18)37-24-7-3-2-6-23(24)36(27(37)39)17-26(38)35-12-4-5-19(16-35)28(29,30)31/h2-3,6-11,13-15,19H,4-5,12,16-17H2,1H3	CDRONGCKHQNJSS-UHFFFAOYSA-N	793760	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[3-(trifluoromethyl)-1-piperidyl]ethyl]benzimidazol-2-one::US20260055102, Example 23	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793760	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793760&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960223	528825223							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729252	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCOC(C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C27H23F3N6O3/c1-33-23-14-31-12-19(20(23)13-32-33)17-6-8-18(9-7-17)36-22-5-3-2-4-21(22)35(26(36)38)16-25(37)34-10-11-39-24(15-34)27(28,29)30/h2-9,12-14,24H,10-11,15-16H2,1H3	SMETUFAOMRMIKS-UHFFFAOYSA-N	793761	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 24	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793761	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793761&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960430	528825224							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729253	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCOC(C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C27H23F3N6O3/c1-33-23-14-31-12-19(20(23)13-32-33)17-6-8-18(9-7-17)36-22-5-3-2-4-21(22)35(26(36)38)16-25(37)34-10-11-39-24(15-34)27(28,29)30/h2-9,12-14,24H,10-11,15-16H2,1H3	SMETUFAOMRMIKS-UHFFFAOYSA-N	793761	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 24	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793761	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793761&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960430	528825224							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729254	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCC[C@H]5C(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C27H24F2N6O2/c1-32-24-15-30-13-19(20(24)14-31-32)17-8-10-18(11-9-17)35-22-6-3-2-5-21(22)34(27(35)37)16-25(36)33-12-4-7-23(33)26(28)29/h2-3,5-6,8-11,13-15,23,26H,4,7,12,16H2,1H3	ZEJSZHOLUQYXKC-UHFFFAOYSA-N	793762	1-[2-[(2S)-2-(difluoromethyl)-pyrrolidin-1-yl]-2-oxo-ethyl]-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]benzimidazol-2-one::US20260055102, Example 25	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793762	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793762&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			178422892	528825225							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729255	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCC[C@H]5C(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C27H24F2N6O2/c1-32-24-15-30-13-19(20(24)14-31-32)17-8-10-18(11-9-17)35-22-6-3-2-5-21(22)34(27(35)37)16-25(36)33-12-4-7-23(33)26(28)29/h2-3,5-6,8-11,13-15,23,26H,4,7,12,16H2,1H3	ZEJSZHOLUQYXKC-UHFFFAOYSA-N	793762	1-[2-[(2S)-2-(difluoromethyl)-pyrrolidin-1-yl]-2-oxo-ethyl]-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]benzimidazol-2-one::US20260055102, Example 25	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793762	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793762&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			178422892	528825225							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729256	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCC[C@H]1CF	InChI=1S/C28H27FN6O2/c1-18-5-3-7-24-27(18)35(28(37)34(24)17-26(36)33-12-4-6-21(33)13-29)20-10-8-19(9-11-20)22-14-30-16-25-23(22)15-31-32(25)2/h3,5,7-11,14-16,21H,4,6,12-13,17H2,1-2H3	COZJVMVXAAHJAI-UHFFFAOYSA-N	793763	4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[(2S)-2-(fluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 26	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793763	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793763&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960318	528825226							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729257	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCC[C@H]1CF	InChI=1S/C28H27FN6O2/c1-18-5-3-7-24-27(18)35(28(37)34(24)17-26(36)33-12-4-6-21(33)13-29)20-10-8-19(9-11-20)22-14-30-16-25-23(22)15-31-32(25)2/h3,5,7-11,14-16,21H,4,6,12-13,17H2,1-2H3	COZJVMVXAAHJAI-UHFFFAOYSA-N	793763	4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[(2S)-2-(fluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 26	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793763	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793763&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960318	528825226							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729258	C[C@@H]1CCCN1C(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21	InChI=1S/C27H26N6O2/c1-18-6-5-13-31(18)26(34)17-32-23-7-3-4-8-24(23)33(27(32)35)20-11-9-19(10-12-20)21-14-28-16-25-22(21)15-29-30(25)2/h3-4,7-12,14-16,18H,5-6,13,17H2,1-2H3	HNEOZINDADLFRD-UHFFFAOYSA-N	793764	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-[(2R)-2-methylpyrrolidin-1-yl]-2-oxoethyl]benzimidazol-2-one::US20260055102, Example 27	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793764	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793764&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960443	528825227							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729259	C[C@@H]1CCCN1C(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21	InChI=1S/C27H26N6O2/c1-18-6-5-13-31(18)26(34)17-32-23-7-3-4-8-24(23)33(27(32)35)20-11-9-19(10-12-20)21-14-28-16-25-22(21)15-29-30(25)2/h3-4,7-12,14-16,18H,5-6,13,17H2,1-2H3	HNEOZINDADLFRD-UHFFFAOYSA-N	793764	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-[(2R)-2-methylpyrrolidin-1-yl]-2-oxoethyl]benzimidazol-2-one::US20260055102, Example 27	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793764	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793764&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960443	528825227							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729260	CC(CC(F)(F)F)NC(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21	InChI=1S/C26H23F3N6O2/c1-16(11-26(27,28)29)32-24(36)15-34-21-5-3-4-6-22(21)35(25(34)37)18-9-7-17(8-10-18)19-12-30-14-23-20(19)13-31-33(23)2/h3-10,12-14,16H,11,15H2,1-2H3,(H,32,36)	JIFRCZIHLLAFBH-UHFFFAOYSA-N	793765	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(3,3,3-trifluoro-1-methyl-propyl)acetamide::US20260055102, Example 28	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793765	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793765&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960180	528825228							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729261	CC(CC(F)(F)F)NC(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21	InChI=1S/C26H23F3N6O2/c1-16(11-26(27,28)29)32-24(36)15-34-21-5-3-4-6-22(21)35(25(34)37)18-9-7-17(8-10-18)19-12-30-14-23-20(19)13-31-33(23)2/h3-10,12-14,16H,11,15H2,1-2H3,(H,32,36)	JIFRCZIHLLAFBH-UHFFFAOYSA-N	793765	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(3,3,3-trifluoro-1-methyl-propyl)acetamide::US20260055102, Example 28	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793765	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793765&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960180	528825228							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729262	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCC[C@@H](C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C28H25F3N6O2/c1-34-25-15-32-13-21(22(25)14-33-34)18-8-10-20(11-9-18)37-24-7-3-2-6-23(24)36(27(37)39)17-26(38)35-12-4-5-19(16-35)28(29,30)31/h2-3,6-11,13-15,19H,4-5,12,16-17H2,1H3	CDRONGCKHQNJSS-UHFFFAOYSA-N	793766	1-[4-(1-methylpyrazolo[3,4-c]-pyridin-4-yl)phenyl]-3-[2-oxo-2-[(3R)-3-(trifluoromethyl)-1-piperidyl]ethyl]benzimidazol-2-one::US20260055102, Example 29	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793766	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793766&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960394	528825229							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729263	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCC[C@@H](C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C28H25F3N6O2/c1-34-25-15-32-13-21(22(25)14-33-34)18-8-10-20(11-9-18)37-24-7-3-2-6-23(24)36(27(37)39)17-26(38)35-12-4-5-19(16-35)28(29,30)31/h2-3,6-11,13-15,19H,4-5,12,16-17H2,1H3	CDRONGCKHQNJSS-UHFFFAOYSA-N	793766	1-[4-(1-methylpyrazolo[3,4-c]-pyridin-4-yl)phenyl]-3-[2-oxo-2-[(3R)-3-(trifluoromethyl)-1-piperidyl]ethyl]benzimidazol-2-one::US20260055102, Example 29	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793766	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793766&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960394	528825229							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729264	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCCC[C@@H]5C(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C28H25F3N6O2/c1-34-24-16-32-14-20(21(24)15-33-34)18-9-11-19(12-10-18)37-23-7-3-2-6-22(23)36(27(37)39)17-26(38)35-13-5-4-8-25(35)28(29,30)31/h2-3,6-7,9-12,14-16,25H,4-5,8,13,17H2,1H3	BFGORKDMHLKZCM-UHFFFAOYSA-N	793767	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[(2R)-2-(trifluoromethyl)-1-piperidyl]ethyl]benzimidazol-2-one::US20260055102, Example 30	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793767	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793767&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960339	528825230							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729265	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCCC[C@@H]5C(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C28H25F3N6O2/c1-34-24-16-32-14-20(21(24)15-33-34)18-9-11-19(12-10-18)37-23-7-3-2-6-22(23)36(27(37)39)17-26(38)35-13-5-4-8-25(35)28(29,30)31/h2-3,6-7,9-12,14-16,25H,4-5,8,13,17H2,1H3	BFGORKDMHLKZCM-UHFFFAOYSA-N	793767	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[(2R)-2-(trifluoromethyl)-1-piperidyl]ethyl]benzimidazol-2-one::US20260055102, Example 30	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793767	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793767&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960339	528825230							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729266	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCC[C@H](C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C28H25F3N6O2/c1-34-25-15-32-13-21(22(25)14-33-34)18-8-10-20(11-9-18)37-24-7-3-2-6-23(24)36(27(37)39)17-26(38)35-12-4-5-19(16-35)28(29,30)31/h2-3,6-11,13-15,19H,4-5,12,16-17H2,1H3	CDRONGCKHQNJSS-UHFFFAOYSA-N	793768	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[(3S)-3-(trifluoromethyl)-1-piperidyl]ethyl]benzimidazol-2-one::US20260055102, Example 31	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793768	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793768&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			174195680	528825231							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729267	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCC[C@H](C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C28H25F3N6O2/c1-34-25-15-32-13-21(22(25)14-33-34)18-8-10-20(11-9-18)37-24-7-3-2-6-23(24)36(27(37)39)17-26(38)35-12-4-5-19(16-35)28(29,30)31/h2-3,6-11,13-15,19H,4-5,12,16-17H2,1H3	CDRONGCKHQNJSS-UHFFFAOYSA-N	793768	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[(3S)-3-(trifluoromethyl)-1-piperidyl]ethyl]benzimidazol-2-one::US20260055102, Example 31	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793768	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793768&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			174195680	528825231							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729268	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCCC[C@H]5C(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C28H25F3N6O2/c1-34-24-16-32-14-20(21(24)15-33-34)18-9-11-19(12-10-18)37-23-7-3-2-6-22(23)36(27(37)39)17-26(38)35-13-5-4-8-25(35)28(29,30)31/h2-3,6-7,9-12,14-16,25H,4-5,8,13,17H2,1H3	BFGORKDMHLKZCM-UHFFFAOYSA-N	793769	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[(2S)-2-(trifluoromethyl)-1-piperidyl]ethyl]benzimidazol-2-one::US20260055102, Example 32	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793769	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793769&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960489	528825232							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729269	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCCC[C@H]5C(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C28H25F3N6O2/c1-34-24-16-32-14-20(21(24)15-33-34)18-9-11-19(12-10-18)37-23-7-3-2-6-22(23)36(27(37)39)17-26(38)35-13-5-4-8-25(35)28(29,30)31/h2-3,6-7,9-12,14-16,25H,4-5,8,13,17H2,1H3	BFGORKDMHLKZCM-UHFFFAOYSA-N	793769	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[(2S)-2-(trifluoromethyl)-1-piperidyl]ethyl]benzimidazol-2-one::US20260055102, Example 32	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793769	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793769&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960489	528825232							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729270	CC(CNC(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21)C(F)(F)F	InChI=1S/C26H23F3N6O2/c1-16(26(27,28)29)11-31-24(36)15-34-21-5-3-4-6-22(21)35(25(34)37)18-9-7-17(8-10-18)19-12-30-14-23-20(19)13-32-33(23)2/h3-10,12-14,16H,11,15H2,1-2H3,(H,31,36)	LIAIBLODIJEXHG-UHFFFAOYSA-N	793770	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(3,3,3-trifluoro-2-methyl-propyl)acetamide::US20260055102, Example 33	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793770	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793770&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960287	528825233							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729271	CC(CNC(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21)C(F)(F)F	InChI=1S/C26H23F3N6O2/c1-16(26(27,28)29)11-31-24(36)15-34-21-5-3-4-6-22(21)35(25(34)37)18-9-7-17(8-10-18)19-12-30-14-23-20(19)13-32-33(23)2/h3-10,12-14,16H,11,15H2,1-2H3,(H,31,36)	LIAIBLODIJEXHG-UHFFFAOYSA-N	793770	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]-N-(3,3,3-trifluoro-2-methyl-propyl)acetamide::US20260055102, Example 33	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793770	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793770&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960287	528825233							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729272	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CC(C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C26H21F3N6O2/c1-32-23-12-30-10-19(20(23)11-31-32)16-6-8-18(9-7-16)35-22-5-3-2-4-21(22)34(25(35)37)15-24(36)33-13-17(14-33)26(27,28)29/h2-12,17H,13-15H2,1H3	PTWCKASSFQFOAU-UHFFFAOYSA-N	793771	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[3-(trifluoromethyl)azetidin-1-yl]-ethyl]benzimidazol-2-one::US20260055102, Example 34	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793771	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793771&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960264	528825234							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729273	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CC(C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C26H21F3N6O2/c1-32-23-12-30-10-19(20(23)11-31-32)16-6-8-18(9-7-16)35-22-5-3-2-4-21(22)34(25(35)37)15-24(36)33-13-17(14-33)26(27,28)29/h2-12,17H,13-15H2,1H3	PTWCKASSFQFOAU-UHFFFAOYSA-N	793771	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[3-(trifluoromethyl)azetidin-1-yl]-ethyl]benzimidazol-2-one::US20260055102, Example 34	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793771	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793771&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960264	528825234							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729274	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CC(F)(F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C25H20F2N6O2/c1-30-22-12-28-10-18(19(22)11-29-30)16-6-8-17(9-7-16)33-21-5-3-2-4-20(21)32(24(33)35)13-23(34)31-14-25(26,27)15-31/h2-12H,13-15H2,1H3	KUUXMNFIBMDOGG-UHFFFAOYSA-N	793772	1-[2-(3,3-difluoroazetidin-1-yl)-2-oxoethyl]-3-[4-(1-methyl-pyrazolo[3,4-c]pyridin-4-yl)-phenyl]benzimidazol-2-one::US20260055102, Example 35	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793772	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793772&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960493	528825235							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729275	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CC(F)(F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C25H20F2N6O2/c1-30-22-12-28-10-18(19(22)11-29-30)16-6-8-17(9-7-16)33-21-5-3-2-4-20(21)32(24(33)35)13-23(34)31-14-25(26,27)15-31/h2-12H,13-15H2,1H3	KUUXMNFIBMDOGG-UHFFFAOYSA-N	793772	1-[2-(3,3-difluoroazetidin-1-yl)-2-oxoethyl]-3-[4-(1-methyl-pyrazolo[3,4-c]pyridin-4-yl)-phenyl]benzimidazol-2-one::US20260055102, Example 35	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793772	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793772&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960493	528825235							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729276	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NC5CC5(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C25H20F2N6O2/c1-31-21-13-28-11-17(18(21)12-29-31)15-6-8-16(9-7-15)33-20-5-3-2-4-19(20)32(24(33)35)14-23(34)30-22-10-25(22,26)27/h2-9,11-13,22H,10,14H2,1H3,(H,30,34)	SAYRQYUWAUOOJD-UHFFFAOYSA-N	793773	N-(2,2-difluorocyclopropyl)-2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]acetamide::US20260055102, Example 36	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793773	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793773&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960498	528825236							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729277	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NC5CC5(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C25H20F2N6O2/c1-31-21-13-28-11-17(18(21)12-29-31)15-6-8-16(9-7-15)33-20-5-3-2-4-19(20)32(24(33)35)14-23(34)30-22-10-25(22,26)27/h2-9,11-13,22H,10,14H2,1H3,(H,30,34)	SAYRQYUWAUOOJD-UHFFFAOYSA-N	793773	N-(2,2-difluorocyclopropyl)-2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxobenzimidazol-1-yl]acetamide::US20260055102, Example 36	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793773	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793773&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960498	528825236							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729278	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCO[C@@H](C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C27H23F3N6O3/c1-33-23-14-31-12-19(20(23)13-32-33)17-6-8-18(9-7-17)36-22-5-3-2-4-21(22)35(26(36)38)16-25(37)34-10-11-39-24(15-34)27(28,29)30/h2-9,12-14,24H,10-11,15-16H2,1H3	SMETUFAOMRMIKS-UHFFFAOYSA-N	793774	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[(2R)-2-(trifluoromethyl)-morpholin-4-yl]ethyl]benz-imidazol-2-one::US20260055102, Example 37	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793774	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793774&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960373	528825237							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729279	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCO[C@@H](C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C27H23F3N6O3/c1-33-23-14-31-12-19(20(23)13-32-33)17-6-8-18(9-7-17)36-22-5-3-2-4-21(22)35(26(36)38)16-25(37)34-10-11-39-24(15-34)27(28,29)30/h2-9,12-14,24H,10-11,15-16H2,1H3	SMETUFAOMRMIKS-UHFFFAOYSA-N	793774	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[(2R)-2-(trifluoromethyl)-morpholin-4-yl]ethyl]benz-imidazol-2-one::US20260055102, Example 37	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793774	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793774&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960373	528825237							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729280	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCO[C@H](C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C27H23F3N6O3/c1-33-23-14-31-12-19(20(23)13-32-33)17-6-8-18(9-7-17)36-22-5-3-2-4-21(22)35(26(36)38)16-25(37)34-10-11-39-24(15-34)27(28,29)30/h2-9,12-14,24H,10-11,15-16H2,1H3	SMETUFAOMRMIKS-UHFFFAOYSA-N	793775	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[(2S)-2-(trifluoromethyl)-morpholin-4-yl]ethyl]benz-imidazol-2-one::US20260055102, Example 38	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793775	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793775&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960241	528825238							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729281	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCO[C@H](C(F)(F)F)C5)c5ccccc54)cc3)cncc21	InChI=1S/C27H23F3N6O3/c1-33-23-14-31-12-19(20(23)13-32-33)17-6-8-18(9-7-17)36-22-5-3-2-4-21(22)35(26(36)38)16-25(37)34-10-11-39-24(15-34)27(28,29)30/h2-9,12-14,24H,10-11,15-16H2,1H3	SMETUFAOMRMIKS-UHFFFAOYSA-N	793775	1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[(2S)-2-(trifluoromethyl)-morpholin-4-yl]ethyl]benz-imidazol-2-one::US20260055102, Example 38	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793775	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793775&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960241	528825238							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729282	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCOCC1C(F)(F)F	InChI=1S/C28H25F3N6O3/c1-17-4-3-5-22-26(17)37(27(39)36(22)15-25(38)35-10-11-40-16-24(35)28(29,30)31)19-8-6-18(7-9-19)20-12-32-14-23-21(20)13-33-34(23)2/h3-9,12-14,24H,10-11,15-16H2,1-2H3	MHCNSJXQWKIBIP-UHFFFAOYSA-N	793776	4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[3-(trifluoromethyl)-morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 39	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793776	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793776&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960350	528825239							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729283	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCOCC1C(F)(F)F	InChI=1S/C28H25F3N6O3/c1-17-4-3-5-22-26(17)37(27(39)36(22)15-25(38)35-10-11-40-16-24(35)28(29,30)31)19-8-6-18(7-9-19)20-12-32-14-23-21(20)13-33-34(23)2/h3-9,12-14,24H,10-11,15-16H2,1-2H3	MHCNSJXQWKIBIP-UHFFFAOYSA-N	793776	4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[3-(trifluoromethyl)-morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 39	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793776	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793776&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960350	528825239							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729284	Cc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)N2CCOC(C(F)(F)F)C2)c2ccccc21	InChI=1S/C28H25F3N6O3/c1-17-11-18(19-12-32-14-24-20(19)13-33-34(24)2)7-8-21(17)37-23-6-4-3-5-22(23)36(27(37)39)16-26(38)35-9-10-40-25(15-35)28(29,30)31/h3-8,11-14,25H,9-10,15-16H2,1-2H3	MCYMHRHXTHHJKD-UHFFFAOYSA-N	793777	1-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 40	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793777	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793777&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960273	528825240							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729285	Cc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)N2CCOC(C(F)(F)F)C2)c2ccccc21	InChI=1S/C28H25F3N6O3/c1-17-11-18(19-12-32-14-24-20(19)13-33-34(24)2)7-8-21(17)37-23-6-4-3-5-22(23)36(27(37)39)16-26(38)35-9-10-40-25(15-35)28(29,30)31/h3-8,11-14,25H,9-10,15-16H2,1-2H3	MCYMHRHXTHHJKD-UHFFFAOYSA-N	793777	1-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-oxo-2-[2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 40	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793777	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793777&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960273	528825240							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729286	O=C(Cn1c(=O)n(-c2ccc(-c3cncc4[nH]ncc34)cc2)c2ccccc21)NCC(F)(F)F	InChI=1S/C23H17F3N6O2/c24-23(25,26)13-28-21(33)12-31-19-3-1-2-4-20(19)32(22(31)34)15-7-5-14(6-8-15)16-9-27-11-18-17(16)10-29-30-18/h1-11H,12-13H2,(H,28,33)(H,29,30)	CDXYMQHPNSEZHD-UHFFFAOYSA-N	793778	2-[2-oxo-3-[4-(1H-pyrazolo[3,4-c]pyridin-4-yl)phenyl]benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 41	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793778	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793778&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960304	528825241							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729287	O=C(Cn1c(=O)n(-c2ccc(-c3cncc4[nH]ncc34)cc2)c2ccccc21)NCC(F)(F)F	InChI=1S/C23H17F3N6O2/c24-23(25,26)13-28-21(33)12-31-19-3-1-2-4-20(19)32(22(31)34)15-7-5-14(6-8-15)16-9-27-11-18-17(16)10-29-30-18/h1-11H,12-13H2,(H,28,33)(H,29,30)	CDXYMQHPNSEZHD-UHFFFAOYSA-N	793778	2-[2-oxo-3-[4-(1H-pyrazolo[3,4-c]pyridin-4-yl)phenyl]benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 41	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793778	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793778&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960304	528825241							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729288	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCO[C@H](C(F)(F)F)C1	InChI=1S/C28H25F3N6O3/c1-17-4-3-5-22-26(17)37(27(39)36(22)16-25(38)35-10-11-40-24(15-35)28(29,30)31)19-8-6-18(7-9-19)20-12-32-14-23-21(20)13-33-34(23)2/h3-9,12-14,24H,10-11,15-16H2,1-2H3	HJWCMDQMYPLKKY-UHFFFAOYSA-N	793779	4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 42	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793779	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793779&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960497	528825242							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729289	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCO[C@H](C(F)(F)F)C1	InChI=1S/C28H25F3N6O3/c1-17-4-3-5-22-26(17)37(27(39)36(22)16-25(38)35-10-11-40-24(15-35)28(29,30)31)19-8-6-18(7-9-19)20-12-32-14-23-21(20)13-33-34(23)2/h3-9,12-14,24H,10-11,15-16H2,1-2H3	HJWCMDQMYPLKKY-UHFFFAOYSA-N	793779	4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 42	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793779	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793779&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960497	528825242							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729290	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCC[C@H]1C(F)F	InChI=1S/C28H26F2N6O2/c1-17-5-3-6-22-26(17)36(28(38)35(22)16-25(37)34-12-4-7-23(34)27(29)30)19-10-8-18(9-11-19)20-13-31-15-24-21(20)14-32-33(24)2/h3,5-6,8-11,13-15,23,27H,4,7,12,16H2,1-2H3	ZPBLCRMFWJKJKD-UHFFFAOYSA-N	793780	1-[2-[(2S)-2-(difluoromethyl)pyrrolidin-1-yl]-2-oxo-ethyl]-4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]benzimidazol-2-one::US20260055102, Example 43	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793780	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793780&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			174197295	528825243							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729291	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCC[C@H]1C(F)F	InChI=1S/C28H26F2N6O2/c1-17-5-3-6-22-26(17)36(28(38)35(22)16-25(37)34-12-4-7-23(34)27(29)30)19-10-8-18(9-11-19)20-13-31-15-24-21(20)14-32-33(24)2/h3,5-6,8-11,13-15,23,27H,4,7,12,16H2,1-2H3	ZPBLCRMFWJKJKD-UHFFFAOYSA-N	793780	1-[2-[(2S)-2-(difluoromethyl)pyrrolidin-1-yl]-2-oxo-ethyl]-4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]benzimidazol-2-one::US20260055102, Example 43	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793780	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793780&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			174197295	528825243							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729292	CC1=CC=CC2C1N(c1ccc(-c3cncc4[nH]ncc34)cc1)C(=O)N2CC(=O)NCC(F)(F)F	InChI=1S/C24H21F3N6O2/c1-14-3-2-4-20-22(14)33(23(35)32(20)12-21(34)29-13-24(25,26)27)16-7-5-15(6-8-16)17-9-28-11-19-18(17)10-30-31-19/h2-11,20,22H,12-13H2,1H3,(H,29,34)(H,30,31)	NMVNIXFVSNMWSS-UHFFFAOYSA-N	793781	2-[4-methyl-2-oxo-3-[4-(1-tetrahydropyran-2-ylpyrazolo[3,4-c]pyridin-4-yl)phenyl]benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 44	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793781	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793781&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			178422893	528825244							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729293	CC1=CC=CC2C1N(c1ccc(-c3cncc4[nH]ncc34)cc1)C(=O)N2CC(=O)NCC(F)(F)F	InChI=1S/C24H21F3N6O2/c1-14-3-2-4-20-22(14)33(23(35)32(20)12-21(34)29-13-24(25,26)27)16-7-5-15(6-8-16)17-9-28-11-19-18(17)10-30-31-19/h2-11,20,22H,12-13H2,1H3,(H,29,34)(H,30,31)	NMVNIXFVSNMWSS-UHFFFAOYSA-N	793781	2-[4-methyl-2-oxo-3-[4-(1-tetrahydropyran-2-ylpyrazolo[3,4-c]pyridin-4-yl)phenyl]benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 44	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793781	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793781&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			178422893	528825244							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729294	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCC[C@H]1CF	InChI=1S/C28H27FN6O2/c1-18-5-3-7-24-27(18)35(28(37)34(24)17-26(36)33-12-4-6-21(33)13-29)20-10-8-19(9-11-20)22-14-30-16-25-23(22)15-31-32(25)2/h3,5,7-11,14-16,21H,4,6,12-13,17H2,1-2H3	COZJVMVXAAHJAI-UHFFFAOYSA-N	793782	1-[2-[(2S)-2-(fluoromethyl)pyrrolidin-1-yl]-2-oxo-ethyl]-4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]benzimidazol-2-one::US20260055102, Example 45	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793782	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793782&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960318	528825245							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729295	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N1CCC[C@H]1CF	InChI=1S/C28H27FN6O2/c1-18-5-3-7-24-27(18)35(28(37)34(24)17-26(36)33-12-4-6-21(33)13-29)20-10-8-19(9-11-20)22-14-30-16-25-23(22)15-31-32(25)2/h3,5,7-11,14-16,21H,4,6,12-13,17H2,1-2H3	COZJVMVXAAHJAI-UHFFFAOYSA-N	793782	1-[2-[(2S)-2-(fluoromethyl)pyrrolidin-1-yl]-2-oxo-ethyl]-4-methyl-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]benzimidazol-2-one::US20260055102, Example 45	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793782	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793782&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960318	528825245							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729296	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCCC(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C25H21F3N6O2/c1-32-22-14-29-12-18(19(22)13-31-32)16-6-8-17(9-7-16)34-21-5-3-2-4-20(21)33(24(34)36)15-23(35)30-11-10-25(26,27)28/h2-9,12-14H,10-11,15H2,1H3,(H,30,35)	GAVBCEKDLZYTFT-UHFFFAOYSA-N	793783	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(3,3,3-trifluoropropyl)acetamide::US20260055102, Example 46	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793783	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793783&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960193	528825246							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729297	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCCC(F)(F)F)c5ccccc54)cc3)cncc21	InChI=1S/C25H21F3N6O2/c1-32-22-14-29-12-18(19(22)13-31-32)16-6-8-17(9-7-16)34-21-5-3-2-4-20(21)33(24(34)36)15-23(35)30-11-10-25(26,27)28/h2-9,12-14H,10-11,15H2,1H3,(H,30,35)	GAVBCEKDLZYTFT-UHFFFAOYSA-N	793783	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(3,3,3-trifluoropropyl)acetamide::US20260055102, Example 46	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793783	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793783&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960193	528825246							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729298	Cc1cccc2c1n(-c1cnc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C23H19F3N8O2/c1-13-4-3-5-17-21(13)34(22(36)33(17)11-20(35)30-12-23(24,25)26)19-10-28-16(8-29-19)14-6-27-9-18-15(14)7-31-32(18)2/h3-10H,11-12H2,1-2H3,(H,30,35)	KAIPXEYARIMLAC-UHFFFAOYSA-N	793784	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 47	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793784	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793784&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960290	528825247							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729299	Cc1cccc2c1n(-c1cnc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C23H19F3N8O2/c1-13-4-3-5-17-21(13)34(22(36)33(17)11-20(35)30-12-23(24,25)26)19-10-28-16(8-29-19)14-6-27-9-18-15(14)7-31-32(18)2/h3-10H,11-12H2,1-2H3,(H,30,35)	KAIPXEYARIMLAC-UHFFFAOYSA-N	793784	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 47	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793784	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793784&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960290	528825247							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729300	Cc1cccc2c1n(-c1cnc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N[C@H](C)C(F)(F)F	InChI=1S/C24H21F3N8O2/c1-13-5-4-6-18-22(13)35(23(37)34(18)12-21(36)32-14(2)24(25,26)27)20-11-29-17(9-30-20)15-7-28-10-19-16(15)8-31-33(19)3/h4-11,14H,12H2,1-3H3,(H,32,36)	XMZXWXCKICUNEN-UHFFFAOYSA-N	793785	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-[(1R)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 48	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793785	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793785&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960402	528825248							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729301	Cc1cccc2c1n(-c1cnc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N[C@H](C)C(F)(F)F	InChI=1S/C24H21F3N8O2/c1-13-5-4-6-18-22(13)35(23(37)34(18)12-21(36)32-14(2)24(25,26)27)20-11-29-17(9-30-20)15-7-28-10-19-16(15)8-31-33(19)3/h4-11,14H,12H2,1-3H3,(H,32,36)	XMZXWXCKICUNEN-UHFFFAOYSA-N	793785	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-[(1R)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 48	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793785	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793785&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960402	528825248							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729302	Cc1cccc2c1n(-c1cnc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C24H21F3N8O2/c1-13-5-4-6-18-22(13)35(23(37)34(18)12-21(36)32-14(2)24(25,26)27)20-11-29-17(9-30-20)15-7-28-10-19-16(15)8-31-33(19)3/h4-11,14H,12H2,1-3H3,(H,32,36)	XMZXWXCKICUNEN-UHFFFAOYSA-N	793786	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 49	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793786&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960459	528825249							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729303	Cc1cccc2c1n(-c1cnc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C24H21F3N8O2/c1-13-5-4-6-18-22(13)35(23(37)34(18)12-21(36)32-14(2)24(25,26)27)20-11-29-17(9-30-20)15-7-28-10-19-16(15)8-31-33(19)3/h4-11,14H,12H2,1-3H3,(H,32,36)	XMZXWXCKICUNEN-UHFFFAOYSA-N	793786	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 49	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793786&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960459	528825249							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729304	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C24H20F3N7O2/c1-14-4-3-5-19-22(14)34(23(36)33(19)12-21(35)30-13-24(25,26)27)15-6-7-18(29-8-15)16-9-28-11-20-17(16)10-31-32(20)2/h3-11H,12-13H2,1-2H3,(H,30,35)	OLTUXECLZKOJCC-UHFFFAOYSA-N	793787	2-[4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 50	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793787	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793787&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960362	528825250							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729305	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C24H20F3N7O2/c1-14-4-3-5-19-22(14)34(23(36)33(19)12-21(35)30-13-24(25,26)27)15-6-7-18(29-8-15)16-9-28-11-20-17(16)10-31-32(20)2/h3-11H,12-13H2,1-2H3,(H,30,35)	OLTUXECLZKOJCC-UHFFFAOYSA-N	793787	2-[4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 50	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793787	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793787&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960362	528825250							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729306	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)N[C@H](C)C(F)(F)F	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-20-23(14)35(24(37)34(20)13-22(36)32-15(2)25(26,27)28)16-7-8-19(30-9-16)17-10-29-12-21-18(17)11-31-33(21)3/h4-12,15H,13H2,1-3H3,(H,32,36)	SBRPWFGEVBYCLT-UHFFFAOYSA-N	793788	2-[4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-[(1R)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 51	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793788	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793788&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960297	528825251							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729307	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)N[C@H](C)C(F)(F)F	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-20-23(14)35(24(37)34(20)13-22(36)32-15(2)25(26,27)28)16-7-8-19(30-9-16)17-10-29-12-21-18(17)11-31-33(21)3/h4-12,15H,13H2,1-3H3,(H,32,36)	SBRPWFGEVBYCLT-UHFFFAOYSA-N	793788	2-[4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-[(1R)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 51	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793788	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793788&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960297	528825251							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729308	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-20-23(14)35(24(37)34(20)13-22(36)32-15(2)25(26,27)28)16-7-8-19(30-9-16)17-10-29-12-21-18(17)11-31-33(21)3/h4-12,15H,13H2,1-3H3,(H,32,36)	SBRPWFGEVBYCLT-UHFFFAOYSA-N	793789	2-[4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 52	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793789	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793789&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960207	528825252							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729309	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-20-23(14)35(24(37)34(20)13-22(36)32-15(2)25(26,27)28)16-7-8-19(30-9-16)17-10-29-12-21-18(17)11-31-33(21)3/h4-12,15H,13H2,1-3H3,(H,32,36)	SBRPWFGEVBYCLT-UHFFFAOYSA-N	793789	2-[4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 52	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793789	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793789&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960207	528825252							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729310	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)N1CCOC[C@H]1C(F)(F)F	InChI=1S/C27H24F3N7O3/c1-16-4-3-5-21-25(16)37(26(39)36(21)14-24(38)35-8-9-40-15-23(35)27(28,29)30)17-6-7-20(32-10-17)18-11-31-13-22-19(18)12-33-34(22)2/h3-7,10-13,23H,8-9,14-15H2,1-2H3	RXORABDRTZYFFT-UHFFFAOYSA-N	793790	4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-1-[2-oxo-2-[(3S)-3-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 53	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793790	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793790&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960328	528825253							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729311	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)N1CCOC[C@H]1C(F)(F)F	InChI=1S/C27H24F3N7O3/c1-16-4-3-5-21-25(16)37(26(39)36(21)14-24(38)35-8-9-40-15-23(35)27(28,29)30)17-6-7-20(32-10-17)18-11-31-13-22-19(18)12-33-34(22)2/h3-7,10-13,23H,8-9,14-15H2,1-2H3	RXORABDRTZYFFT-UHFFFAOYSA-N	793790	4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-1-[2-oxo-2-[(3S)-3-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 53	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793790	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793790&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960328	528825253							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729312	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)N1CCO[C@H](C(F)(F)F)C1	InChI=1S/C27H24F3N7O3/c1-16-4-3-5-21-25(16)37(26(39)36(21)15-24(38)35-8-9-40-23(14-35)27(28,29)30)17-6-7-20(32-10-17)18-11-31-13-22-19(18)12-33-34(22)2/h3-7,10-13,23H,8-9,14-15H2,1-2H3	BDBILBWWFUGMDN-UHFFFAOYSA-N	793791	4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 54	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793791	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793791&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960338	528825254							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729313	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)N1CCO[C@H](C(F)(F)F)C1	InChI=1S/C27H24F3N7O3/c1-16-4-3-5-21-25(16)37(26(39)36(21)15-24(38)35-8-9-40-23(14-35)27(28,29)30)17-6-7-20(32-10-17)18-11-31-13-22-19(18)12-33-34(22)2/h3-7,10-13,23H,8-9,14-15H2,1-2H3	BDBILBWWFUGMDN-UHFFFAOYSA-N	793791	4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 54	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793791	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793791&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960338	528825254							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729314	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)N1CCO[C@H](C(F)(F)F)C1	InChI=1S/C27H24F3N7O3/c1-16-4-3-5-21-25(16)37(26(39)36(21)15-24(38)35-8-9-40-23(14-35)27(28,29)30)17-6-7-20(32-10-17)18-11-31-13-22-19(18)12-33-34(22)2/h3-7,10-13,23H,8-9,14-15H2,1-2H3	BDBILBWWFUGMDN-UHFFFAOYSA-N	793792	4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 55	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793792	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793792&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960338	528825255							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729315	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)N1CCO[C@H](C(F)(F)F)C1	InChI=1S/C27H24F3N7O3/c1-16-4-3-5-21-25(16)37(26(39)36(21)15-24(38)35-8-9-40-23(14-35)27(28,29)30)17-6-7-20(32-10-17)18-11-31-13-22-19(18)12-33-34(22)2/h3-7,10-13,23H,8-9,14-15H2,1-2H3	BDBILBWWFUGMDN-UHFFFAOYSA-N	793792	4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 55	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793792	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793792&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960338	528825255							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729316	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)N1CCC[C@H]1C(F)(F)F	InChI=1S/C27H24F3N7O2/c1-16-5-3-6-21-25(16)37(26(39)36(21)15-24(38)35-10-4-7-23(35)27(28,29)30)17-8-9-20(32-11-17)18-12-31-14-22-19(18)13-33-34(22)2/h3,5-6,8-9,11-14,23H,4,7,10,15H2,1-2H3	TWPGNSKIMLLYIU-UHFFFAOYSA-N	793793	4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 56	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793793	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793793&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960419	528825256							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729317	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)N1CCC[C@H]1C(F)(F)F	InChI=1S/C27H24F3N7O2/c1-16-5-3-6-21-25(16)37(26(39)36(21)15-24(38)35-10-4-7-23(35)27(28,29)30)17-8-9-20(32-11-17)18-12-31-14-22-19(18)13-33-34(22)2/h3,5-6,8-9,11-14,23H,4,7,10,15H2,1-2H3	TWPGNSKIMLLYIU-UHFFFAOYSA-N	793793	4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 56	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793793	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793793&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960419	528825256							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729318	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-23(14)35(24(37)34(19)13-22(36)32-15(2)25(26,27)28)21-8-7-16(9-30-21)17-10-29-12-20-18(17)11-31-33(20)3/h4-12,15H,13H2,1-3H3,(H,32,36)	ZLKFIRRHDMODCD-UHFFFAOYSA-N	793794	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 57	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793794	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793794&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960352	528825257							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729319	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-23(14)35(24(37)34(19)13-22(36)32-15(2)25(26,27)28)21-8-7-16(9-30-21)17-10-29-12-20-18(17)11-31-33(20)3/h4-12,15H,13H2,1-3H3,(H,32,36)	ZLKFIRRHDMODCD-UHFFFAOYSA-N	793794	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 57	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793794	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793794&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960352	528825257							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729320	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-23(14)35(24(37)34(19)13-22(36)32-15(2)25(26,27)28)21-8-7-16(9-30-21)17-10-29-12-20-18(17)11-31-33(20)3/h4-12,15H,13H2,1-3H3,(H,32,36)	ZLKFIRRHDMODCD-UHFFFAOYSA-N	793795	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 58	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793795	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793795&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960352	528825258							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729321	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-23(14)35(24(37)34(19)13-22(36)32-15(2)25(26,27)28)21-8-7-16(9-30-21)17-10-29-12-20-18(17)11-31-33(20)3/h4-12,15H,13H2,1-3H3,(H,32,36)	ZLKFIRRHDMODCD-UHFFFAOYSA-N	793795	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 58	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793795	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793795&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960352	528825258							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729322	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N1CCC[C@H]1C(F)(F)F	InChI=1S/C27H24F3N7O2/c1-16-5-3-6-20-25(16)37(26(39)36(20)15-24(38)35-10-4-7-22(35)27(28,29)30)23-9-8-17(11-32-23)18-12-31-14-21-19(18)13-33-34(21)2/h3,5-6,8-9,11-14,22H,4,7,10,15H2,1-2H3	INSADGPWZCRCKF-UHFFFAOYSA-N	793796	4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 59	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793796	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793796&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			174197323	528825259							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729323	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N1CCC[C@H]1C(F)(F)F	InChI=1S/C27H24F3N7O2/c1-16-5-3-6-20-25(16)37(26(39)36(20)15-24(38)35-10-4-7-22(35)27(28,29)30)23-9-8-17(11-32-23)18-12-31-14-21-19(18)13-33-34(21)2/h3,5-6,8-9,11-14,22H,4,7,10,15H2,1-2H3	INSADGPWZCRCKF-UHFFFAOYSA-N	793796	4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 59	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793796	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793796&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			174197323	528825259							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729324	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N1CCO[C@@H](C(F)(F)F)C1	InChI=1S/C27H24F3N7O3/c1-16-4-3-5-20-25(16)37(26(39)36(20)15-24(38)35-8-9-40-22(14-35)27(28,29)30)23-7-6-17(10-32-23)18-11-31-13-21-19(18)12-33-34(21)2/h3-7,10-13,22H,8-9,14-15H2,1-2H3	URPXVOACVISTDC-UHFFFAOYSA-N	793798	4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-1-[2-oxo-2-[(2R)-2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 60	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793798	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793798&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			178422894	528825261							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729325	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N1CCO[C@@H](C(F)(F)F)C1	InChI=1S/C27H24F3N7O3/c1-16-4-3-5-20-25(16)37(26(39)36(20)15-24(38)35-8-9-40-22(14-35)27(28,29)30)23-7-6-17(10-32-23)18-11-31-13-21-19(18)12-33-34(21)2/h3-7,10-13,22H,8-9,14-15H2,1-2H3	URPXVOACVISTDC-UHFFFAOYSA-N	793798	4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-1-[2-oxo-2-[(2R)-2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 60	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793798	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793798&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			178422894	528825261							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729326	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N1CCO[C@H](C(F)(F)F)C1	InChI=1S/C27H24F3N7O3/c1-16-4-3-5-20-25(16)37(26(39)36(20)15-24(38)35-8-9-40-22(14-35)27(28,29)30)23-7-6-17(10-32-23)18-11-31-13-21-19(18)12-33-34(21)2/h3-7,10-13,22H,8-9,14-15H2,1-2H3	URPXVOACVISTDC-UHFFFAOYSA-N	793799	4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 61	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793799	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793799&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			178422895	528825262							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729327	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N1CCO[C@H](C(F)(F)F)C1	InChI=1S/C27H24F3N7O3/c1-16-4-3-5-20-25(16)37(26(39)36(20)15-24(38)35-8-9-40-22(14-35)27(28,29)30)23-7-6-17(10-32-23)18-11-31-13-21-19(18)12-33-34(21)2/h3-7,10-13,22H,8-9,14-15H2,1-2H3	URPXVOACVISTDC-UHFFFAOYSA-N	793799	4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)morpholin-4-yl]ethyl]benzimidazol-2-one::US20260055102, Example 61	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793799	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793799&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			178422895	528825262							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729328	C[C@@H](CC(F)(F)F)NC(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21	InChI=1S/C26H23F3N6O2/c1-16(11-26(27,28)29)32-24(36)15-34-21-5-3-4-6-22(21)35(25(34)37)18-9-7-17(8-10-18)19-12-30-14-23-20(19)13-31-33(23)2/h3-10,12-14,16H,11,15H2,1-2H3,(H,32,36)	JIFRCZIHLLAFBH-UHFFFAOYSA-N	793800	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-3,3,3-trifluoro-1-methyl-propyl]acetamide::US20260055102, Example 62	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793800	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793800&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960392	528825263							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729329	C[C@@H](CC(F)(F)F)NC(=O)Cn1c(=O)n(-c2ccc(-c3cncc4c3cnn4C)cc2)c2ccccc21	InChI=1S/C26H23F3N6O2/c1-16(11-26(27,28)29)32-24(36)15-34-21-5-3-4-6-22(21)35(25(34)37)18-9-7-17(8-10-18)19-12-30-14-23-20(19)13-31-33(23)2/h3-10,12-14,16H,11,15H2,1-2H3,(H,32,36)	JIFRCZIHLLAFBH-UHFFFAOYSA-N	793800	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-3,3,3-trifluoro-1-methyl-propyl]acetamide::US20260055102, Example 62	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793800	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793800&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960392	528825263							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729330	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)nc3)cncc21	InChI=1S/C23H18F3N7O2/c1-31-19-11-27-9-15(16(19)10-30-31)14-6-7-20(28-8-14)33-18-5-3-2-4-17(18)32(22(33)35)12-21(34)29-13-23(24,25)26/h2-11H,12-13H2,1H3,(H,29,34)	AJWVHHAVIXXRHQ-UHFFFAOYSA-N	793801	2-[3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 63	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793801	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793801&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960429	528825264							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729331	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)nc3)cncc21	InChI=1S/C23H18F3N7O2/c1-31-19-11-27-9-15(16(19)10-30-31)14-6-7-20(28-8-14)33-18-5-3-2-4-17(18)32(22(33)35)12-21(34)29-13-23(24,25)26/h2-11H,12-13H2,1H3,(H,29,34)	AJWVHHAVIXXRHQ-UHFFFAOYSA-N	793801	2-[3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 63	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793801	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793801&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960429	528825264							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729332	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-23(14)35(24(37)34(19)13-22(36)32-15(2)25(26,27)28)21-8-7-16(9-30-21)17-10-29-12-20-18(17)11-31-33(20)3/h4-12,15H,13H2,1-3H3,(H,32,36)	ZLKFIRRHDMODCD-UHFFFAOYSA-N	793802	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 64	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793802	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793802&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960352	528825265							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729333	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-23(14)35(24(37)34(19)13-22(36)32-15(2)25(26,27)28)21-8-7-16(9-30-21)17-10-29-12-20-18(17)11-31-33(20)3/h4-12,15H,13H2,1-3H3,(H,32,36)	ZLKFIRRHDMODCD-UHFFFAOYSA-N	793802	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 64	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793802	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793802&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960352	528825265							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729334	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCC[C@H]5C(F)(F)F)c5ccccc54)cn3)cncc21	InChI=1S/C26H22F3N7O2/c1-33-22-14-30-12-17(18(22)13-32-33)19-9-8-16(11-31-19)36-21-6-3-2-5-20(21)35(25(36)38)15-24(37)34-10-4-7-23(34)26(27,28)29/h2-3,5-6,8-9,11-14,23H,4,7,10,15H2,1H3	RKBUELPHTSTART-UHFFFAOYSA-N	793803	1-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-3-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 65	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793803	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793803&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			174195734	528825266							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729335	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCC[C@H]5C(F)(F)F)c5ccccc54)cn3)cncc21	InChI=1S/C26H22F3N7O2/c1-33-22-14-30-12-17(18(22)13-32-33)19-9-8-16(11-31-19)36-21-6-3-2-5-20(21)35(25(36)38)15-24(37)34-10-4-7-23(34)26(27,28)29/h2-3,5-6,8-9,11-14,23H,4,7,10,15H2,1H3	RKBUELPHTSTART-UHFFFAOYSA-N	793803	1-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-3-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]benzimidazol-2-one::US20260055102, Example 65	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793803	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793803&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			174195734	528825266							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729336	Cc1cccc2c1n(-c1ncc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C23H19F3N8O2/c1-13-4-3-5-17-20(13)34(22(36)33(17)11-19(35)30-12-23(24,25)26)21-28-6-14(7-29-21)15-8-27-10-18-16(15)9-31-32(18)2/h3-10H,11-12H2,1-2H3,(H,30,35)	WFRRMDCSUVSPKO-UHFFFAOYSA-N	793804	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrimidin-2-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 66	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793804	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793804&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960444	528825267							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729337	Cc1cccc2c1n(-c1ncc(-c3cncc4c3cnn4C)cn1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C23H19F3N8O2/c1-13-4-3-5-17-20(13)34(22(36)33(17)11-19(35)30-12-23(24,25)26)21-28-6-14(7-29-21)15-8-27-10-18-16(15)9-31-32(18)2/h3-10H,11-12H2,1-2H3,(H,30,35)	WFRRMDCSUVSPKO-UHFFFAOYSA-N	793804	2-[4-methyl-3-[5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrimidin-2-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 66	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793804	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793804&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960444	528825267							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729338	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nn1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C23H19F3N8O2/c1-13-4-3-5-17-21(13)34(22(36)33(17)11-20(35)28-12-23(24,25)26)19-7-6-16(30-31-19)14-8-27-10-18-15(14)9-29-32(18)2/h3-10H,11-12H2,1-2H3,(H,28,35)	DSYYKWLCNXKCPF-UHFFFAOYSA-N	793805	2-[4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyridazin-3-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 67	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793805	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793805&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960414	528825268							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729339	Cc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)nn1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C23H19F3N8O2/c1-13-4-3-5-17-21(13)34(22(36)33(17)11-20(35)28-12-23(24,25)26)19-7-6-16(30-31-19)14-8-27-10-18-15(14)9-29-32(18)2/h3-10H,11-12H2,1-2H3,(H,28,35)	DSYYKWLCNXKCPF-UHFFFAOYSA-N	793805	2-[4-methyl-3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyridazin-3-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 67	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793805	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793805&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960414	528825268							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729340	Cc1cccc2c1n(-c1ccc(-c3cncc4[nH]ncc34)nc1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C24H20F3N7O2/c1-13-4-3-5-20-22(13)34(23(36)33(20)12-21(35)31-14(2)24(25,26)27)15-6-7-18(29-8-15)16-9-28-11-19-17(16)10-30-32-19/h3-11,14H,12H2,1-2H3,(H,30,32)(H,31,35)	CUVIJLMERITQQY-UHFFFAOYSA-N	793806	2-[4-methyl-2-oxo-3-[6-(1H-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 68	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793806	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793806&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960408	528825269							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729341	Cc1cccc2c1n(-c1ccc(-c3cncc4[nH]ncc34)nc1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C24H20F3N7O2/c1-13-4-3-5-20-22(13)34(23(36)33(20)12-21(35)31-14(2)24(25,26)27)15-6-7-18(29-8-15)16-9-28-11-19-17(16)10-30-32-19/h3-11,14H,12H2,1-2H3,(H,30,32)(H,31,35)	CUVIJLMERITQQY-UHFFFAOYSA-N	793806	2-[4-methyl-2-oxo-3-[6-(1H-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 68	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793806	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793806&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960408	528825269							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729342	Cc1cccc2c1n(-c1ccc(-c3cncc4[nH]ncc34)cn1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C24H20F3N7O2/c1-13-4-3-5-19-22(13)34(23(36)33(19)12-21(35)31-14(2)24(25,26)27)20-7-6-15(8-29-20)16-9-28-11-18-17(16)10-30-32-18/h3-11,14H,12H2,1-2H3,(H,30,32)(H,31,35)	GAOZZLDJNCXVRB-UHFFFAOYSA-N	793807	2-[4-methyl-2-oxo-3-[5-(1H-pyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 69	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793807	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793807&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960311	528825270							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729343	Cc1cccc2c1n(-c1ccc(-c3cncc4[nH]ncc34)cn1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C24H20F3N7O2/c1-13-4-3-5-19-22(13)34(23(36)33(19)12-21(35)31-14(2)24(25,26)27)20-7-6-15(8-29-20)16-9-28-11-18-17(16)10-30-32-18/h3-11,14H,12H2,1-2H3,(H,30,32)(H,31,35)	GAOZZLDJNCXVRB-UHFFFAOYSA-N	793807	2-[4-methyl-2-oxo-3-[5-(1H-pyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 69	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793807	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793807&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960311	528825270							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729344	Cc1cccc2c1n(-c1ccc(-c3cncc4[nH]ncc34)cn1)c(=O)n2CC(=O)N1CCO[C@H](C(F)(F)F)C1	InChI=1S/C26H22F3N7O3/c1-15-3-2-4-20-24(15)36(22-6-5-16(9-31-22)17-10-30-12-19-18(17)11-32-33-19)25(38)35(20)14-23(37)34-7-8-39-21(13-34)26(27,28)29/h2-6,9-12,21H,7-8,13-14H2,1H3,(H,32,33)	XEUANMVQMCYSIN-UHFFFAOYSA-N	793808	4-methyl-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)morpholin-4-yl]ethyl]-3-[5-(1H-pyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]benzimidazol-2-one::US20260055102, Example 70	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793808	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793808&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960369	528825271							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729345	Cc1cccc2c1n(-c1ccc(-c3cncc4[nH]ncc34)cn1)c(=O)n2CC(=O)N1CCO[C@H](C(F)(F)F)C1	InChI=1S/C26H22F3N7O3/c1-15-3-2-4-20-24(15)36(22-6-5-16(9-31-22)17-10-30-12-19-18(17)11-32-33-19)25(38)35(20)14-23(37)34-7-8-39-21(13-34)26(27,28)29/h2-6,9-12,21H,7-8,13-14H2,1H3,(H,32,33)	XEUANMVQMCYSIN-UHFFFAOYSA-N	793808	4-methyl-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)morpholin-4-yl]ethyl]-3-[5-(1H-pyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]benzimidazol-2-one::US20260055102, Example 70	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793808	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793808&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960369	528825271							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729346	Cc1cccc2c1n(-c1ccc(-c3cncc4[nH]ncc34)cn1)c(=O)n2CC(=O)N1CCO[C@@H](C(F)(F)F)C1	InChI=1S/C26H22F3N7O3/c1-15-3-2-4-20-24(15)36(22-6-5-16(9-31-22)17-10-30-12-19-18(17)11-32-33-19)25(38)35(20)14-23(37)34-7-8-39-21(13-34)26(27,28)29/h2-6,9-12,21H,7-8,13-14H2,1H3,(H,32,33)	XEUANMVQMCYSIN-UHFFFAOYSA-N	793809	4-methyl-1-[2-oxo-2-[(2R)-2-(trifluoromethyl)morpholin-4-yl]ethyl]-3-[5-(1H-pyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]benzimidazol-2-one::US20260055102, Example 71	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793809&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960488	528825272							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729347	Cc1cccc2c1n(-c1ccc(-c3cncc4[nH]ncc34)cn1)c(=O)n2CC(=O)N1CCO[C@@H](C(F)(F)F)C1	InChI=1S/C26H22F3N7O3/c1-15-3-2-4-20-24(15)36(22-6-5-16(9-31-22)17-10-30-12-19-18(17)11-32-33-19)25(38)35(20)14-23(37)34-7-8-39-21(13-34)26(27,28)29/h2-6,9-12,21H,7-8,13-14H2,1H3,(H,32,33)	XEUANMVQMCYSIN-UHFFFAOYSA-N	793809	4-methyl-1-[2-oxo-2-[(2R)-2-(trifluoromethyl)morpholin-4-yl]ethyl]-3-[5-(1H-pyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]benzimidazol-2-one::US20260055102, Example 71	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793809&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960488	528825272							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729348	Cc1cccc2c1n(-c1ccc(-c3cncc4[nH]ncc34)cn1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C23H18F3N7O2/c1-13-3-2-4-18-21(13)33(22(35)32(18)11-20(34)29-12-23(24,25)26)19-6-5-14(7-28-19)15-8-27-10-17-16(15)9-30-31-17/h2-10H,11-12H2,1H3,(H,29,34)(H,30,31)	ZNOHHSAWITUYKL-UHFFFAOYSA-N	793810	2-[4-methyl-2-oxo-3-[5-(1H-pyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 72	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793810&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960199	528825273							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729349	Cc1cccc2c1n(-c1ccc(-c3cncc4[nH]ncc34)cn1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C23H18F3N7O2/c1-13-3-2-4-18-21(13)33(22(35)32(18)11-20(34)29-12-23(24,25)26)19-6-5-14(7-28-19)15-8-27-10-17-16(15)9-30-31-17/h2-10H,11-12H2,1H3,(H,29,34)(H,30,31)	ZNOHHSAWITUYKL-UHFFFAOYSA-N	793810	2-[4-methyl-2-oxo-3-[5-(1H-pyrazolo[3,4-c]pyridin-4-yl)-2-pyridyl]benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 72	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793810&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960199	528825273							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729350	Cc1cccc2c1n(-c1ncc(-c3cncc4[nH]ncc34)cn1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C23H19F3N8O2/c1-12-4-3-5-18-20(12)34(22(36)33(18)11-19(35)31-13(2)23(24,25)26)21-28-6-14(7-29-21)15-8-27-10-17-16(15)9-30-32-17/h3-10,13H,11H2,1-2H3,(H,30,32)(H,31,35)	NNBOFIPBBUNUTC-UHFFFAOYSA-N	793811	2-[4-methyl-2-oxo-3-[5-(1H-pyrazolo[3,4-c]pyridin-4-yl)pyrimidin-2-yl]benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 73	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793811	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793811&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960206	528825274							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729351	Cc1cccc2c1n(-c1ncc(-c3cncc4[nH]ncc34)cn1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C23H19F3N8O2/c1-12-4-3-5-18-20(12)34(22(36)33(18)11-19(35)31-13(2)23(24,25)26)21-28-6-14(7-29-21)15-8-27-10-17-16(15)9-30-32-17/h3-10,13H,11H2,1-2H3,(H,30,32)(H,31,35)	NNBOFIPBBUNUTC-UHFFFAOYSA-N	793811	2-[4-methyl-2-oxo-3-[5-(1H-pyrazolo[3,4-c]pyridin-4-yl)pyrimidin-2-yl]benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 73	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793811	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793811&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960206	528825274							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729352	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5cccc(C#N)c54)cc3)cncc21	InChI=1S/C25H18F3N7O2/c1-33-21-12-30-10-18(19(21)11-32-33)15-5-7-17(8-6-15)35-23-16(9-29)3-2-4-20(23)34(24(35)37)13-22(36)31-14-25(26,27)28/h2-8,10-12H,13-14H2,1H3,(H,31,36)	YGALFCFKCVBBCY-UHFFFAOYSA-N	793812	2-[4-cyano-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 74	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793812	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793812&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960460	528825275							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729353	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5cccc(C#N)c54)cc3)cncc21	InChI=1S/C25H18F3N7O2/c1-33-21-12-30-10-18(19(21)11-32-33)15-5-7-17(8-6-15)35-23-16(9-29)3-2-4-20(23)34(24(35)37)13-22(36)31-14-25(26,27)28/h2-8,10-12H,13-14H2,1H3,(H,31,36)	YGALFCFKCVBBCY-UHFFFAOYSA-N	793812	2-[4-cyano-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 74	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793812	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793812&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960460	528825275							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729354	Cc1cccc2c1n(-c1cnc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C23H19F3N8O2/c1-13-4-3-5-17-20(13)34(22(36)33(17)11-19(35)30-12-23(24,25)26)14-6-28-21(29-7-14)16-8-27-10-18-15(16)9-31-32(18)2/h3-10H,11-12H2,1-2H3,(H,30,35)	GCHVKUHFUIEXRH-UHFFFAOYSA-N	793813	2-[4-methyl-3-[2-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrimidin-5-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 75	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793813	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793813&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960426	528825276							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729355	Cc1cccc2c1n(-c1cnc(-c3cncc4c3cnn4C)nc1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C23H19F3N8O2/c1-13-4-3-5-17-20(13)34(22(36)33(17)11-19(35)30-12-23(24,25)26)14-6-28-21(29-7-14)16-8-27-10-18-15(16)9-31-32(18)2/h3-10H,11-12H2,1-2H3,(H,30,35)	GCHVKUHFUIEXRH-UHFFFAOYSA-N	793813	2-[4-methyl-3-[2-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrimidin-5-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 75	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793813	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793813&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960426	528825276							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729356	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5cccnc54)cc3)cncc21	InChI=1S/C23H18F3N7O2/c1-31-19-11-27-9-16(17(19)10-30-31)14-4-6-15(7-5-14)33-21-18(3-2-8-28-21)32(22(33)35)12-20(34)29-13-23(24,25)26/h2-11H,12-13H2,1H3,(H,29,34)	YUDOGQHJDGJZME-UHFFFAOYSA-N	793814	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-imidazo[4,5-b]pyridin-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 76	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793814	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793814&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960343	528825277							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729357	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5cccnc54)cc3)cncc21	InChI=1S/C23H18F3N7O2/c1-31-19-11-27-9-16(17(19)10-30-31)14-4-6-15(7-5-14)33-21-18(3-2-8-28-21)32(22(33)35)12-20(34)29-13-23(24,25)26/h2-11H,12-13H2,1H3,(H,29,34)	YUDOGQHJDGJZME-UHFFFAOYSA-N	793814	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-imidazo[4,5-b]pyridin-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 76	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793814	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793814&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960343	528825277							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729358	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccncc54)cc3)cncc21	InChI=1S/C23H18F3N7O2/c1-31-19-10-28-8-16(17(19)9-30-31)14-2-4-15(5-3-14)33-20-11-27-7-6-18(20)32(22(33)35)12-21(34)29-13-23(24,25)26/h2-11H,12-13H2,1H3,(H,29,34)	NDPYECRQHUWTBP-UHFFFAOYSA-N	793815	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-imidazo[4,5-c]pyridin-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 77	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793815	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793815&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960382	528825278							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729359	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccncc54)cc3)cncc21	InChI=1S/C23H18F3N7O2/c1-31-19-10-28-8-16(17(19)9-30-31)14-2-4-15(5-3-14)33-20-11-27-7-6-18(20)32(22(33)35)12-21(34)29-13-23(24,25)26/h2-11H,12-13H2,1H3,(H,29,34)	NDPYECRQHUWTBP-UHFFFAOYSA-N	793815	2-[3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-imidazo[4,5-c]pyridin-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 77	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793815	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793815&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960382	528825278							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729360	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5cnccc54)cc3)cncc21	InChI=1S/C23H18F3N7O2/c1-31-19-10-28-8-16(17(19)9-30-31)14-2-4-15(5-3-14)33-18-6-7-27-11-20(18)32(22(33)35)12-21(34)29-13-23(24,25)26/h2-11H,12-13H2,1H3,(H,29,34)	XPSKSQCAQQOTPD-UHFFFAOYSA-N	793816	2-[1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-imidazo[4,5-c]pyridin-3-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 78	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793816	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793816&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960456	528825279							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729361	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5cnccc54)cc3)cncc21	InChI=1S/C23H18F3N7O2/c1-31-19-10-28-8-16(17(19)9-30-31)14-2-4-15(5-3-14)33-18-6-7-27-11-20(18)32(22(33)35)12-21(34)29-13-23(24,25)26/h2-11H,12-13H2,1H3,(H,29,34)	XPSKSQCAQQOTPD-UHFFFAOYSA-N	793816	2-[1-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-imidazo[4,5-c]pyridin-3-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 78	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793816	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793816&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960456	528825279							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729362	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCC[C@H]5C(F)(F)F)c5cccnc54)cc3)cncc21	InChI=1S/C26H22F3N7O2/c1-33-21-14-30-12-18(19(21)13-32-33)16-6-8-17(9-7-16)36-24-20(4-2-10-31-24)35(25(36)38)15-23(37)34-11-3-5-22(34)26(27,28)29/h2,4,6-10,12-14,22H,3,5,11,15H2,1H3	GHQSXTSRWJBITQ-UHFFFAOYSA-N	793817	3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]imidazo[4,5-b]pyridin-2-one::US20260055102, Example 79	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793817	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793817&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960431	528825280							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729363	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)N5CCC[C@H]5C(F)(F)F)c5cccnc54)cc3)cncc21	InChI=1S/C26H22F3N7O2/c1-33-21-14-30-12-18(19(21)13-32-33)16-6-8-17(9-7-16)36-24-20(4-2-10-31-24)35(25(36)38)15-23(37)34-11-3-5-22(34)26(27,28)29/h2,4,6-10,12-14,22H,3,5,11,15H2,1H3	GHQSXTSRWJBITQ-UHFFFAOYSA-N	793817	3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-1-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]imidazo[4,5-b]pyridin-2-one::US20260055102, Example 79	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793817	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793817&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960431	528825280							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729364	CN(C)c1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C26H24F3N7O2/c1-33(2)20-5-4-6-21-24(20)36(25(38)35(21)14-23(37)31-15-26(27,28)29)17-9-7-16(8-10-17)18-11-30-13-22-19(18)12-32-34(22)3/h4-13H,14-15H2,1-3H3,(H,31,37)	FSHCAHHOWLOOCK-UHFFFAOYSA-N	793818	2-[4-(dimethylamino)-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 80	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793818	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793818&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960492	528825281							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729365	CN(C)c1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C26H24F3N7O2/c1-33(2)20-5-4-6-21-24(20)36(25(38)35(21)14-23(37)31-15-26(27,28)29)17-9-7-16(8-10-17)18-11-30-13-22-19(18)12-32-34(22)3/h4-13H,14-15H2,1-3H3,(H,31,37)	FSHCAHHOWLOOCK-UHFFFAOYSA-N	793818	2-[4-(dimethylamino)-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 80	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793818	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793818&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960492	528825281							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729366	COc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1C)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C26H23F3N6O3/c1-15-9-16(17-10-30-12-21-18(17)11-32-33(21)2)7-8-19(15)35-24-20(5-4-6-22(24)38-3)34(25(35)37)13-23(36)31-14-26(27,28)29/h4-12H,13-14H2,1-3H3,(H,31,36)	FVWDDOXQAJORQC-UHFFFAOYSA-N	793819	2-[4-methoxy-3-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 81	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793819&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960424	528825282							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729367	COc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1C)c(=O)n2CC(=O)NCC(F)(F)F	InChI=1S/C26H23F3N6O3/c1-15-9-16(17-10-30-12-21-18(17)11-32-33(21)2)7-8-19(15)35-24-20(5-4-6-22(24)38-3)34(25(35)37)13-23(36)31-14-26(27,28)29/h4-12H,13-14H2,1-3H3,(H,31,36)	FVWDDOXQAJORQC-UHFFFAOYSA-N	793819	2-[4-methoxy-3-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 81	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793819&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960424	528825282							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729368	Cc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C27H25F3N6O2/c1-15-6-5-7-22-25(15)36(26(38)35(22)14-24(37)33-17(3)27(28,29)30)21-9-8-18(10-16(21)2)19-11-31-13-23-20(19)12-32-34(23)4/h5-13,17H,14H2,1-4H3,(H,33,37)	DYBITPWYUHBGCG-UHFFFAOYSA-N	793820	2-[4-methyl-3-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 82	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793820&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			178422896	528825283							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729369	Cc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C27H25F3N6O2/c1-15-6-5-7-22-25(15)36(26(38)35(22)14-24(37)33-17(3)27(28,29)30)21-9-8-18(10-16(21)2)19-11-31-13-23-20(19)12-32-34(23)4/h5-13,17H,14H2,1-4H3,(H,33,37)	DYBITPWYUHBGCG-UHFFFAOYSA-N	793820	2-[4-methyl-3-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 82	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793820&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			178422896	528825283							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729370	Cc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(Cl)c21	InChI=1S/C25H20ClF3N6O2/c1-14-8-15(16-9-30-11-21-17(16)10-32-33(21)2)6-7-19(14)35-23-18(26)4-3-5-20(23)34(24(35)37)12-22(36)31-13-25(27,28)29/h3-11H,12-13H2,1-2H3,(H,31,36)	TXNCXJAWVOGQLF-UHFFFAOYSA-N	793821	2-[4-chloro-3-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 83	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793821	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793821&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960310	528825284							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729371	Cc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(Cl)c21	InChI=1S/C25H20ClF3N6O2/c1-14-8-15(16-9-30-11-21-17(16)10-32-33(21)2)6-7-19(14)35-23-18(26)4-3-5-20(23)34(24(35)37)12-22(36)31-13-25(27,28)29/h3-11H,12-13H2,1-2H3,(H,31,36)	TXNCXJAWVOGQLF-UHFFFAOYSA-N	793821	2-[4-chloro-3-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 83	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793821	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793821&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960310	528825284							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729372	Cc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c2cccc(Cl)c21	InChI=1S/C26H22ClF3N6O2/c1-14-9-16(17-10-31-12-22-18(17)11-32-34(22)3)7-8-20(14)36-24-19(27)5-4-6-21(24)35(25(36)38)13-23(37)33-15(2)26(28,29)30/h4-12,15H,13H2,1-3H3,(H,33,37)	BOCBSYJILLJKDY-UHFFFAOYSA-N	793822	2-[4-chloro-3-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 84	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793822	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793822&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960357	528825285							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729373	Cc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c2cccc(Cl)c21	InChI=1S/C26H22ClF3N6O2/c1-14-9-16(17-10-31-12-22-18(17)11-32-34(22)3)7-8-20(14)36-24-19(27)5-4-6-21(24)35(25(36)38)13-23(37)33-15(2)26(28,29)30/h4-12,15H,13H2,1-3H3,(H,33,37)	BOCBSYJILLJKDY-UHFFFAOYSA-N	793822	2-[4-chloro-3-[2-methyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 84	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793822	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793822&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960357	528825285							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729374	COc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C26H23F3N6O3/c1-15(26(27,28)29)32-23(36)14-34-20-5-4-6-22(38-3)24(20)35(25(34)37)17-9-7-16(8-10-17)18-11-30-13-21-19(18)12-31-33(21)2/h4-13,15H,14H2,1-3H3,(H,32,36)	DLCLTKJSFPCTPF-UHFFFAOYSA-N	793823	2-[4-methoxy-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 85	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793823&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960501	528825286							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729375	COc1cccc2c1n(-c1ccc(-c3cncc4c3cnn4C)cc1)c(=O)n2CC(=O)N[C@@H](C)C(F)(F)F	InChI=1S/C26H23F3N6O3/c1-15(26(27,28)29)32-23(36)14-34-20-5-4-6-22(38-3)24(20)35(25(34)37)17-9-7-16(8-10-17)18-11-30-13-21-19(18)12-31-33(21)2/h4-13,15H,14H2,1-3H3,(H,32,36)	DLCLTKJSFPCTPF-UHFFFAOYSA-N	793823	2-[4-methoxy-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 85	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793823&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960501	528825286							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729376	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5cccc(F)c54)cc3)cncc21	InChI=1S/C24H18F4N6O2/c1-32-20-11-29-9-16(17(20)10-31-32)14-5-7-15(8-6-14)34-22-18(25)3-2-4-19(22)33(23(34)36)12-21(35)30-13-24(26,27)28/h2-11H,12-13H2,1H3,(H,30,35)	JIQGXSDAYBUPJT-UHFFFAOYSA-N	793824	2-[4-fluoro-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 86	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793824&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960441	528825287							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729377	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5cccc(F)c54)cc3)cncc21	InChI=1S/C24H18F4N6O2/c1-32-20-11-29-9-16(17(20)10-31-32)14-5-7-15(8-6-14)34-22-18(25)3-2-4-19(22)33(23(34)36)12-21(35)30-13-24(26,27)28/h2-11H,12-13H2,1H3,(H,30,35)	JIQGXSDAYBUPJT-UHFFFAOYSA-N	793824	2-[4-fluoro-3-[4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 86	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793824&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960441	528825287							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729378	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)c(Cl)c3)cncc21	InChI=1S/C24H18ClF3N6O2/c1-32-21-11-29-9-15(16(21)10-31-32)14-6-7-18(17(25)8-14)34-20-5-3-2-4-19(20)33(23(34)36)12-22(35)30-13-24(26,27)28/h2-11H,12-13H2,1H3,(H,30,35)	NOWNWMSJUROXLB-UHFFFAOYSA-N	793825	2-[3-[2-chloro-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 87	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793825	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793825&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960363	528825288							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729379	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)c(Cl)c3)cncc21	InChI=1S/C24H18ClF3N6O2/c1-32-21-11-29-9-15(16(21)10-31-32)14-6-7-18(17(25)8-14)34-20-5-3-2-4-19(20)33(23(34)36)12-22(35)30-13-24(26,27)28/h2-11H,12-13H2,1H3,(H,30,35)	NOWNWMSJUROXLB-UHFFFAOYSA-N	793825	2-[3-[2-chloro-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 87	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793825	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793825&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960363	528825288							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729380	COc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2ccccc21	InChI=1S/C25H21F3N6O3/c1-32-21-12-29-10-16(17(21)11-31-32)15-7-8-20(22(9-15)37-2)34-19-6-4-3-5-18(19)33(24(34)36)13-23(35)30-14-25(26,27)28/h3-12H,13-14H2,1-2H3,(H,30,35)	SFIIEKKGSVZKFR-UHFFFAOYSA-N	793826	2-[3-[2-methoxy-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 88	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793826	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793826&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960380	528825289							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729381	COc1cc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2ccccc21	InChI=1S/C25H21F3N6O3/c1-32-21-12-29-10-16(17(21)11-31-32)15-7-8-20(22(9-15)37-2)34-19-6-4-3-5-18(19)33(24(34)36)13-23(35)30-14-25(26,27)28/h3-12H,13-14H2,1-2H3,(H,30,35)	SFIIEKKGSVZKFR-UHFFFAOYSA-N	793826	2-[3-[2-methoxy-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 88	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793826	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793826&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960380	528825289							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729382	Cn1ncc2c(-c3cc(F)c(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)c(F)c3)cncc21	InChI=1S/C24H17F5N6O2/c1-33-20-10-30-8-14(15(20)9-32-33)13-6-16(25)22(17(26)7-13)35-19-5-3-2-4-18(19)34(23(35)37)11-21(36)31-12-24(27,28)29/h2-10H,11-12H2,1H3,(H,31,36)	SBTFXXPHDOHXQC-UHFFFAOYSA-N	793827	2-[3-[2,6-difluoro-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 89	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793827	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793827&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960226	528825290							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729383	Cn1ncc2c(-c3cc(F)c(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)c(F)c3)cncc21	InChI=1S/C24H17F5N6O2/c1-33-20-10-30-8-14(15(20)9-32-33)13-6-16(25)22(17(26)7-13)35-19-5-3-2-4-18(19)34(23(35)37)11-21(36)31-12-24(27,28)29/h2-10H,11-12H2,1H3,(H,31,36)	SBTFXXPHDOHXQC-UHFFFAOYSA-N	793827	2-[3-[2,6-difluoro-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 89	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793827	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793827&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960226	528825290							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729384	Cc1cc(-c2cncc3c2cnn3C)cc(C)c1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2ccccc21	InChI=1S/C26H23F3N6O2/c1-15-8-17(18-10-30-12-22-19(18)11-32-33(22)3)9-16(2)24(15)35-21-7-5-4-6-20(21)34(25(35)37)13-23(36)31-14-26(27,28)29/h4-12H,13-14H2,1-3H3,(H,31,36)	ZKPSUKBIXZRVJF-UHFFFAOYSA-N	793828	2-[3-[2,6-dimethyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 90	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793828	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793828&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960302	528825291							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729385	Cc1cc(-c2cncc3c2cnn3C)cc(C)c1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2ccccc21	InChI=1S/C26H23F3N6O2/c1-15-8-17(18-10-30-12-22-19(18)11-32-33(22)3)9-16(2)24(15)35-21-7-5-4-6-20(21)34(25(35)37)13-23(36)31-14-26(27,28)29/h4-12H,13-14H2,1-3H3,(H,31,36)	ZKPSUKBIXZRVJF-UHFFFAOYSA-N	793828	2-[3-[2,6-dimethyl-4-(1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 90	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793828	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793828&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960302	528825291							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729386	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)cn3)cncc21	InChI=1S/C23H18F3N7O2/c1-31-20-11-27-9-15(16(20)10-30-31)17-7-6-14(8-28-17)33-19-5-3-2-4-18(19)32(22(33)35)12-21(34)29-13-23(24,25)26/h2-11H,12-13H2,1H3,(H,29,34)	SSFCKSYWKZRNPQ-UHFFFAOYSA-N	793829	2-[3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 91	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793829	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793829&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960404	528825292							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729387	Cn1ncc2c(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5ccccc54)cn3)cncc21	InChI=1S/C23H18F3N7O2/c1-31-20-11-27-9-15(16(20)10-30-31)17-7-6-14(8-28-17)33-19-5-3-2-4-18(19)32(22(33)35)12-21(34)29-13-23(24,25)26/h2-11H,12-13H2,1H3,(H,29,34)	SSFCKSYWKZRNPQ-UHFFFAOYSA-N	793829	2-[3-[6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 91	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793829	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793829&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960404	528825292							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729388	Cc1nn(C)c2cncc(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5cccc(C)c54)cn3)c12	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-23(14)35(24(37)34(19)12-21(36)31-13-25(26,27)28)16-7-8-18(30-9-16)17-10-29-11-20-22(17)15(2)32-33(20)3/h4-11H,12-13H2,1-3H3,(H,31,36)	AQUKBTFFIMNTCX-UHFFFAOYSA-N	793830	2-[3-[6-(1,3-dimethylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-4-methyl-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 92	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793830	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793830&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960434	528825293							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729389	Cc1nn(C)c2cncc(-c3ccc(-n4c(=O)n(CC(=O)NCC(F)(F)F)c5cccc(C)c54)cn3)c12	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-23(14)35(24(37)34(19)12-21(36)31-13-25(26,27)28)16-7-8-18(30-9-16)17-10-29-11-20-22(17)15(2)32-33(20)3/h4-11H,12-13H2,1-3H3,(H,31,36)	AQUKBTFFIMNTCX-UHFFFAOYSA-N	793830	2-[3-[6-(1,3-dimethylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-4-methyl-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 92	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793830	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793830&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960434	528825293							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729390	Cc1cc(-c2cncc3[nH]ncc23)ncc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C24H20F3N7O2/c1-13-4-3-5-19-22(13)34(23(36)33(19)11-21(35)30-12-24(25,26)27)20-10-29-17(6-14(20)2)15-7-28-9-18-16(15)8-31-32-18/h3-10H,11-12H2,1-2H3,(H,30,35)(H,31,32)	HHNJZUYFJXKXNQ-UHFFFAOYSA-N	793831	2-[4-methyl-3-[4-methyl-6-(1H-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 93	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793831&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960378	528825294							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729391	Cc1cc(-c2cncc3[nH]ncc23)ncc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C24H20F3N7O2/c1-13-4-3-5-19-22(13)34(23(36)33(19)11-21(35)30-12-24(25,26)27)20-10-29-17(6-14(20)2)15-7-28-9-18-16(15)8-31-32-18/h3-10H,11-12H2,1-2H3,(H,30,35)(H,31,32)	HHNJZUYFJXKXNQ-UHFFFAOYSA-N	793831	2-[4-methyl-3-[4-methyl-6-(1H-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 93	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793831&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960378	528825294							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729392	Cc1nc(-c2cncc3[nH]ncc23)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C24H20F3N7O2/c1-13-4-3-5-20-22(13)34(23(36)33(20)11-21(35)29-12-24(25,26)27)19-7-6-17(31-14(19)2)15-8-28-10-18-16(15)9-30-32-18/h3-10H,11-12H2,1-2H3,(H,29,35)(H,30,32)	LSLKPXCMYHSVEQ-UHFFFAOYSA-N	793832	2-[4-methyl-3-[2-methyl-6-(1H-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 94	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793832	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793832&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960468	528825295							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729393	Cc1nc(-c2cncc3[nH]ncc23)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C24H20F3N7O2/c1-13-4-3-5-20-22(13)34(23(36)33(20)11-21(35)29-12-24(25,26)27)19-7-6-17(31-14(19)2)15-8-28-10-18-16(15)9-30-32-18/h3-10H,11-12H2,1-2H3,(H,29,35)(H,30,32)	LSLKPXCMYHSVEQ-UHFFFAOYSA-N	793832	2-[4-methyl-3-[2-methyl-6-(1H-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 94	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793832	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793832&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960468	528825295							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729394	Cc1nc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-20-23(14)35(24(37)34(20)12-22(36)30-13-25(26,27)28)19-8-7-18(32-15(19)2)16-9-29-11-21-17(16)10-31-33(21)3/h4-11H,12-13H2,1-3H3,(H,30,36)	DFTJZEQMRJJKRM-UHFFFAOYSA-N	793833	2-[4-methyl-3-[2-methyl-6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 95	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793833	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793833&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960313	528825296							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729395	Cc1nc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-20-23(14)35(24(37)34(20)12-22(36)30-13-25(26,27)28)19-8-7-18(32-15(19)2)16-9-29-11-21-17(16)10-31-33(21)3/h4-11H,12-13H2,1-3H3,(H,30,36)	DFTJZEQMRJJKRM-UHFFFAOYSA-N	793833	2-[4-methyl-3-[2-methyl-6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 95	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793833	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793833&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960313	528825296							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729396	Cc1nc(-c2cncc3c2cnn3C)cnc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C24H21F3N8O2/c1-13-5-4-6-18-21(13)35(23(37)34(18)11-20(36)30-12-24(25,26)27)22-14(2)32-17(9-29-22)15-7-28-10-19-16(15)8-31-33(19)3/h4-10H,11-12H2,1-3H3,(H,30,36)	ZYNALRAGTOWUDH-UHFFFAOYSA-N	793834	2-[4-methyl-3-[3-methyl-5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 96	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793834&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960388	528825297							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729397	Cc1nc(-c2cncc3c2cnn3C)cnc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C24H21F3N8O2/c1-13-5-4-6-18-21(13)35(23(37)34(18)11-20(36)30-12-24(25,26)27)22-14(2)32-17(9-29-22)15-7-28-10-19-16(15)8-31-33(19)3/h4-10H,11-12H2,1-3H3,(H,30,36)	ZYNALRAGTOWUDH-UHFFFAOYSA-N	793834	2-[4-methyl-3-[3-methyl-5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 96	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793834&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960388	528825297							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729398	Cc1cc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3cccc(C)c32)cnc1-c1cncc2c1cnn2C	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-23(14)35(24(37)34(19)12-21(36)31-13-25(26,27)28)16-7-15(2)22(30-8-16)18-9-29-11-20-17(18)10-32-33(20)3/h4-11H,12-13H2,1-3H3,(H,31,36)	PUEDSNAEJFBBEF-UHFFFAOYSA-N	793835	2-[4-methyl-3-[5-methyl-6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 97	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793835	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793835&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960245	528825298							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729399	Cc1cc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3cccc(C)c32)cnc1-c1cncc2c1cnn2C	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-23(14)35(24(37)34(19)12-21(36)31-13-25(26,27)28)16-7-15(2)22(30-8-16)18-9-29-11-20-17(18)10-32-33(20)3/h4-11H,12-13H2,1-3H3,(H,31,36)	PUEDSNAEJFBBEF-UHFFFAOYSA-N	793835	2-[4-methyl-3-[5-methyl-6-(1-methylpyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 97	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793835	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793835&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960245	528825298							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729400	Cc1cccc2c1n(-c1ncc(-c3cncc4[nH]ncc34)cn1)c(=O)n2CC(=O)N[C@H](C)C(F)(F)F	InChI=1S/C23H19F3N8O2/c1-12-4-3-5-18-20(12)34(22(36)33(18)11-19(35)31-13(2)23(24,25)26)21-28-6-14(7-29-21)15-8-27-10-17-16(15)9-30-32-17/h3-10,13H,11H2,1-2H3,(H,30,32)(H,31,35)	NNBOFIPBBUNUTC-UHFFFAOYSA-N	793836	2-[4-methyl-2-oxo-3-[5-(1H-pyrazolo[3,4-c]pyridin-4-yl)pyrimidin-2-yl]benzimidazol-1-yl]-N-[(1R)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 98	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793836	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793836&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960420	528825299							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729401	Cc1cccc2c1n(-c1ncc(-c3cncc4[nH]ncc34)cn1)c(=O)n2CC(=O)N[C@H](C)C(F)(F)F	InChI=1S/C23H19F3N8O2/c1-12-4-3-5-18-20(12)34(22(36)33(18)11-19(35)31-13(2)23(24,25)26)21-28-6-14(7-29-21)15-8-27-10-17-16(15)9-30-32-17/h3-10,13H,11H2,1-2H3,(H,30,32)(H,31,35)	NNBOFIPBBUNUTC-UHFFFAOYSA-N	793836	2-[4-methyl-2-oxo-3-[5-(1H-pyrazolo[3,4-c]pyridin-4-yl)pyrimidin-2-yl]benzimidazol-1-yl]-N-[(1R)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 98	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793836	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793836&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960420	528825299							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729402	Cc1cc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3cccc(C)c32)cnc1-c1cncc2[nH]ncc12	InChI=1S/C24H20F3N7O2/c1-13-4-3-5-19-22(13)34(23(36)33(19)11-20(35)30-12-24(25,26)27)15-6-14(2)21(29-7-15)17-8-28-10-18-16(17)9-31-32-18/h3-10H,11-12H2,1-2H3,(H,30,35)(H,31,32)	HDOHDVVNMMNVCU-UHFFFAOYSA-N	793837	2-[4-methyl-3-[5-methyl-6-(1H-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 99	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793837	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793837&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960406	528825300							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729403	Cc1cc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3cccc(C)c32)cnc1-c1cncc2[nH]ncc12	InChI=1S/C24H20F3N7O2/c1-13-4-3-5-19-22(13)34(23(36)33(19)11-20(35)30-12-24(25,26)27)15-6-14(2)21(29-7-15)17-8-28-10-18-16(17)9-31-32-18/h3-10H,11-12H2,1-2H3,(H,30,35)(H,31,32)	HDOHDVVNMMNVCU-UHFFFAOYSA-N	793837	2-[4-methyl-3-[5-methyl-6-(1H-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 99	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793837	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793837&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960406	528825300							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729404	Cc1nc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3cccc(C)c32)cnc1-c1cncc2c1cnn2C	InChI=1S/C24H21F3N8O2/c1-13-5-4-6-17-22(13)35(23(37)34(17)11-20(36)30-12-24(25,26)27)19-10-29-21(14(2)32-19)16-7-28-9-18-15(16)8-31-33(18)3/h4-10H,11-12H2,1-3H3,(H,30,36)	ZQUZVNCHADDKRW-UHFFFAOYSA-N	793838	2-[4-methyl-3-[6-methyl-5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 100	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793838	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793838&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960462	528825301							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729405	Cc1nc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3cccc(C)c32)cnc1-c1cncc2c1cnn2C	InChI=1S/C24H21F3N8O2/c1-13-5-4-6-17-22(13)35(23(37)34(17)11-20(36)30-12-24(25,26)27)19-10-29-21(14(2)32-19)16-7-28-9-18-15(16)8-31-33(18)3/h4-10H,11-12H2,1-3H3,(H,30,36)	ZQUZVNCHADDKRW-UHFFFAOYSA-N	793838	2-[4-methyl-3-[6-methyl-5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 100	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793838	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793838&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960462	528825301							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729406	Cc1nc(-n2c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c3cccc(C)c32)cnc1-c1cncc2c1cnn2C	InChI=1S/C25H23F3N8O2/c1-13-6-5-7-18-23(13)36(24(38)35(18)12-21(37)33-15(3)25(26,27)28)20-11-30-22(14(2)32-20)17-8-29-10-19-16(17)9-31-34(19)4/h5-11,15H,12H2,1-4H3,(H,33,37)	GXPBEULNUBDWGF-UHFFFAOYSA-N	793839	2-[4-methyl-3-[6-methyl-5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 101	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793839	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793839&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960508	528825302							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729407	Cc1nc(-n2c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c3cccc(C)c32)cnc1-c1cncc2c1cnn2C	InChI=1S/C25H23F3N8O2/c1-13-6-5-7-18-23(13)36(24(38)35(18)12-21(37)33-15(3)25(26,27)28)20-11-30-22(14(2)32-20)17-8-29-10-19-16(17)9-31-34(19)4/h5-11,15H,12H2,1-4H3,(H,33,37)	GXPBEULNUBDWGF-UHFFFAOYSA-N	793839	2-[4-methyl-3-[6-methyl-5-(1-methylpyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260055102, Example 101	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793839	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793839&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960508	528825302							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729408	Cc1cc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3cccc(C)c32)cnc1-c1cncc2[nH]nc(C)c12	InChI=1S/C25H22F3N7O2/c1-13-5-4-6-19-23(13)35(24(37)34(19)11-20(36)31-12-25(26,27)28)16-7-14(2)22(30-8-16)17-9-29-10-18-21(17)15(3)32-33-18/h4-10H,11-12H2,1-3H3,(H,31,36)(H,32,33)	GTXAFCDLBBETHZ-UHFFFAOYSA-N	793840	2-[4-methyl-3-[5-methyl-6-(3-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 102	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793840	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793840&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960348	528825303							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729409	Cc1cc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3cccc(C)c32)cnc1-c1cncc2[nH]nc(C)c12	InChI=1S/C25H22F3N7O2/c1-13-5-4-6-19-23(13)35(24(37)34(19)11-20(36)31-12-25(26,27)28)16-7-14(2)22(30-8-16)17-9-29-10-18-21(17)15(3)32-33-18/h4-10H,11-12H2,1-3H3,(H,31,36)(H,32,33)	GTXAFCDLBBETHZ-UHFFFAOYSA-N	793840	2-[4-methyl-3-[5-methyl-6-(3-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 102	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793840	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793840&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960348	528825303							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729410	Cc1nc(-c2cncc3[nH]nc(C)c23)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C25H22F3N7O2/c1-13-5-4-6-20-23(13)35(24(37)34(20)11-21(36)30-12-25(26,27)28)19-8-7-17(31-14(19)2)16-9-29-10-18-22(16)15(3)32-33-18/h4-10H,11-12H2,1-3H3,(H,30,36)(H,32,33)	YWYFACHRFXNFSR-UHFFFAOYSA-N	793841	2-[4-methyl-3-[2-methyl-6-(3-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 103	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793841	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793841&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960268	528825304							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729411	Cc1nc(-c2cncc3[nH]nc(C)c23)ccc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C25H22F3N7O2/c1-13-5-4-6-20-23(13)35(24(37)34(20)11-21(36)30-12-25(26,27)28)19-8-7-17(31-14(19)2)16-9-29-10-18-22(16)15(3)32-33-18/h4-10H,11-12H2,1-3H3,(H,30,36)(H,32,33)	YWYFACHRFXNFSR-UHFFFAOYSA-N	793841	2-[4-methyl-3-[2-methyl-6-(3-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 103	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793841	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793841&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960268	528825304							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729412	Cc1nc(-c2cncc3[nH]nc(C)c23)cnc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C24H21F3N8O2/c1-12-5-4-6-18-21(12)35(23(37)34(18)10-19(36)30-11-24(25,26)27)22-14(3)31-16(9-29-22)15-7-28-8-17-20(15)13(2)32-33-17/h4-9H,10-11H2,1-3H3,(H,30,36)(H,32,33)	NUUZUBUGYJHQQP-UHFFFAOYSA-N	793842	2-[4-methyl-3-[3-methyl-5-(3-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 104	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793842&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960340	528825305							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729413	Cc1nc(-c2cncc3[nH]nc(C)c23)cnc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C24H21F3N8O2/c1-12-5-4-6-18-21(12)35(23(37)34(18)10-19(36)30-11-24(25,26)27)22-14(3)31-16(9-29-22)15-7-28-8-17-20(15)13(2)32-33-17/h4-9H,10-11H2,1-3H3,(H,30,36)(H,32,33)	NUUZUBUGYJHQQP-UHFFFAOYSA-N	793842	2-[4-methyl-3-[3-methyl-5-(3-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 104	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793842&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960340	528825305							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729414	Cc1nc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3cccc(C)c32)cnc1-c1cncc2[nH]nc(C)c12	InChI=1S/C24H21F3N8O2/c1-12-5-4-6-17-22(12)35(23(37)34(17)10-19(36)30-11-24(25,26)27)18-9-29-21(14(3)31-18)15-7-28-8-16-20(15)13(2)32-33-16/h4-9H,10-11H2,1-3H3,(H,30,36)(H,32,33)	MMMDGSCYLYPFET-UHFFFAOYSA-N	793843	2-[4-methyl-3-[6-methyl-5-(3-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 105	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793843	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793843&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960249	528825306							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729415	Cc1nc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3cccc(C)c32)cnc1-c1cncc2[nH]nc(C)c12	InChI=1S/C24H21F3N8O2/c1-12-5-4-6-17-22(12)35(23(37)34(17)10-19(36)30-11-24(25,26)27)18-9-29-21(14(3)31-18)15-7-28-8-16-20(15)13(2)32-33-16/h4-9H,10-11H2,1-3H3,(H,30,36)(H,32,33)	MMMDGSCYLYPFET-UHFFFAOYSA-N	793843	2-[4-methyl-3-[6-methyl-5-(3-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl)pyrazin-2-yl]-2-oxo-benzimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260055102, Example 105	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793843	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793843&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960249	528825306							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729416	Cc1cc(-c2cncc3c2cnn3C)ncc1-n1c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-20-24(14)36(25(38)35(20)13-23(37)33-16(3)26(27,28)29)21-12-31-19(8-15(21)2)17-9-30-11-22-18(17)10-32-34(22)4/h5-12,16H,13H2,1-4H3,(H,33,37)	SUWISZKBXGIRNI-UHFFFAOYSA-N	793844	US20260055102, Example 106	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793844	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793844&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960333	528825307							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729417	Cc1cc(-c2cncc3c2cnn3C)ncc1-n1c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-20-24(14)36(25(38)35(20)13-23(37)33-16(3)26(27,28)29)21-12-31-19(8-15(21)2)17-9-30-11-22-18(17)10-32-34(22)4/h5-12,16H,13H2,1-4H3,(H,33,37)	SUWISZKBXGIRNI-UHFFFAOYSA-N	793844	US20260055102, Example 106	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793844	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793844&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960333	528825307							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729418	Cc1cc(-c2cncc3c2cnn3C)ncc1-n1c(=O)n(CC(=O)N[C@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-20-24(14)36(25(38)35(20)13-23(37)33-16(3)26(27,28)29)21-12-31-19(8-15(21)2)17-9-30-11-22-18(17)10-32-34(22)4/h5-12,16H,13H2,1-4H3,(H,33,37)	SUWISZKBXGIRNI-UHFFFAOYSA-N	793845	US20260055102, Example 107	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793845	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793845&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960267	528825308							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729419	Cc1cc(-c2cncc3c2cnn3C)ncc1-n1c(=O)n(CC(=O)N[C@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-20-24(14)36(25(38)35(20)13-23(37)33-16(3)26(27,28)29)21-12-31-19(8-15(21)2)17-9-30-11-22-18(17)10-32-34(22)4/h5-12,16H,13H2,1-4H3,(H,33,37)	SUWISZKBXGIRNI-UHFFFAOYSA-N	793845	US20260055102, Example 107	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793845	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793845&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960267	528825308							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729420	Cc1cc(-c2cncc3c2c(C)nn3C)ncc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-19-24(14)36(25(38)35(19)12-22(37)32-13-26(27,28)29)20-11-31-18(8-15(20)2)17-9-30-10-21-23(17)16(3)33-34(21)4/h5-11H,12-13H2,1-4H3,(H,32,37)	NNQBYWSAFMRMLC-UHFFFAOYSA-N	793846	US20260055102, Example 108	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793846	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793846&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960255	528825309							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729421	Cc1cc(-c2cncc3c2c(C)nn3C)ncc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-19-24(14)36(25(38)35(19)12-22(37)32-13-26(27,28)29)20-11-31-18(8-15(20)2)17-9-30-10-21-23(17)16(3)33-34(21)4/h5-11H,12-13H2,1-4H3,(H,32,37)	NNQBYWSAFMRMLC-UHFFFAOYSA-N	793846	US20260055102, Example 108	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793846	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793846&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960255	528825309							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729422	Cc1ncc2c(cnn2C)c1-c1ccc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3cccc(C)c32)cn1	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-23(14)35(24(37)34(19)12-21(36)31-13-25(26,27)28)16-7-8-18(30-9-16)22-15(2)29-11-20-17(22)10-32-33(20)3/h4-11H,12-13H2,1-3H3,(H,31,36)	MVRZBILGFUCJQT-UHFFFAOYSA-N	793847	US20260055102, Example 109	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793847	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793847&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960335	528825310							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729423	Cc1ncc2c(cnn2C)c1-c1ccc(-n2c(=O)n(CC(=O)NCC(F)(F)F)c3cccc(C)c32)cn1	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-23(14)35(24(37)34(19)12-21(36)31-13-25(26,27)28)16-7-8-18(30-9-16)22-15(2)29-11-20-17(22)10-32-33(20)3/h4-11H,12-13H2,1-3H3,(H,31,36)	MVRZBILGFUCJQT-UHFFFAOYSA-N	793847	US20260055102, Example 109	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793847	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793847&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960335	528825310							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729424	Cc1cc(-c2cncc3c2cnn3C)cnc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-22(14)35(24(37)34(19)12-21(36)31-13-25(26,27)28)23-15(2)7-16(8-30-23)17-9-29-11-20-18(17)10-32-33(20)3/h4-11H,12-13H2,1-3H3,(H,31,36)	DGEGVBSGARWEIC-UHFFFAOYSA-N	793848	US20260055102, Example 110	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793848	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793848&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960187	528825311							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729425	Cc1cc(-c2cncc3c2cnn3C)cnc1-n1c(=O)n(CC(=O)NCC(F)(F)F)c2cccc(C)c21	InChI=1S/C25H22F3N7O2/c1-14-5-4-6-19-22(14)35(24(37)34(19)12-21(36)31-13-25(26,27)28)23-15(2)7-16(8-30-23)17-9-29-11-20-18(17)10-32-33(20)3/h4-11H,12-13H2,1-3H3,(H,31,36)	DGEGVBSGARWEIC-UHFFFAOYSA-N	793848	US20260055102, Example 110	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793848	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793848&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960187	528825311							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729426	Cc1cc(-c2cncc3c2cnn3C)cnc1-n1c(=O)n(CC(=O)N[C@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-20-23(14)36(25(38)35(20)13-22(37)33-16(3)26(27,28)29)24-15(2)8-17(9-31-24)18-10-30-12-21-19(18)11-32-34(21)4/h5-12,16H,13H2,1-4H3,(H,33,37)	KBJTVAJFWWFVNF-UHFFFAOYSA-N	793849	US20260055102, Example 111	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793849	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793849&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960244	528825312							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729427	Cc1cc(-c2cncc3c2cnn3C)cnc1-n1c(=O)n(CC(=O)N[C@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-20-23(14)36(25(38)35(20)13-22(37)33-16(3)26(27,28)29)24-15(2)8-17(9-31-24)18-10-30-12-21-19(18)11-32-34(21)4/h5-12,16H,13H2,1-4H3,(H,33,37)	KBJTVAJFWWFVNF-UHFFFAOYSA-N	793849	US20260055102, Example 111	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793849	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793849&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960244	528825312							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729428	Cc1nc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)N[C@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-21-24(14)36(25(38)35(21)13-23(37)33-16(3)26(27,28)29)20-9-8-19(32-15(20)2)17-10-30-12-22-18(17)11-31-34(22)4/h5-12,16H,13H2,1-4H3,(H,33,37)	QPJRGQAVMKRLPK-UHFFFAOYSA-N	793850	US20260055102, Example 112	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793850	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793850&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960464	528825313							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729429	Cc1nc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)N[C@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-21-24(14)36(25(38)35(21)13-23(37)33-16(3)26(27,28)29)20-9-8-19(32-15(20)2)17-10-30-12-22-18(17)11-31-34(22)4/h5-12,16H,13H2,1-4H3,(H,33,37)	QPJRGQAVMKRLPK-UHFFFAOYSA-N	793850	US20260055102, Example 112	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793850	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793850&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960464	528825313							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729430	Cc1nc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-21-24(14)36(25(38)35(21)13-23(37)33-16(3)26(27,28)29)20-9-8-19(32-15(20)2)17-10-30-12-22-18(17)11-31-34(22)4/h5-12,16H,13H2,1-4H3,(H,33,37)	QPJRGQAVMKRLPK-UHFFFAOYSA-N	793851	US20260055102, Example 113	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793851	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793851&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960278	528825314							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729431	Cc1nc(-c2cncc3c2cnn3C)ccc1-n1c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-21-24(14)36(25(38)35(21)13-23(37)33-16(3)26(27,28)29)20-9-8-19(32-15(20)2)17-10-30-12-22-18(17)11-31-34(22)4/h5-12,16H,13H2,1-4H3,(H,33,37)	QPJRGQAVMKRLPK-UHFFFAOYSA-N	793851	US20260055102, Example 113	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793851	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793851&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960278	528825314							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729432	Cc1cc(-c2cncc3c2cnn3C)cnc1-n1c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-20-23(14)36(25(38)35(20)13-22(37)33-16(3)26(27,28)29)24-15(2)8-17(9-31-24)18-10-30-12-21-19(18)11-32-34(21)4/h5-12,16H,13H2,1-4H3,(H,33,37)	KBJTVAJFWWFVNF-UHFFFAOYSA-N	793852	US20260055102, Example 114	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793852	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793852&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960205	528825315							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729433	Cc1cc(-c2cncc3c2cnn3C)cnc1-n1c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C26H24F3N7O2/c1-14-6-5-7-20-23(14)36(25(38)35(20)13-22(37)33-16(3)26(27,28)29)24-15(2)8-17(9-31-24)18-10-30-12-21-19(18)11-32-34(21)4/h5-12,16H,13H2,1-4H3,(H,33,37)	KBJTVAJFWWFVNF-UHFFFAOYSA-N	793852	US20260055102, Example 114	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793852	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793852&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960205	528825315							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
729434	Cc1nc(-c2cncc3c2cnn3C)cnc1-n1c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C25H23F3N8O2/c1-13-6-5-7-19-22(13)36(24(38)35(19)12-21(37)33-15(3)25(26,27)28)23-14(2)32-18(10-30-23)16-8-29-11-20-17(16)9-31-34(20)4/h5-11,15H,12H2,1-4H3,(H,33,37)	UIRIORCLGZTUAB-UHFFFAOYSA-N	793853	US20260055102, Example 115	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793853	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793853&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170960428	528825316							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
729435	Cc1nc(-c2cncc3c2cnn3C)cnc1-n1c(=O)n(CC(=O)N[C@@H](C)C(F)(F)F)c2cccc(C)c21	InChI=1S/C25H23F3N8O2/c1-13-6-5-7-19-22(13)36(24(38)35(19)12-21(37)33-15(3)25(26,27)28)23-14(2)32-18(10-30-23)16-8-29-11-20-17(16)9-31-34(20)4/h5-11,15H,12H2,1-4H3,(H,33,37)	UIRIORCLGZTUAB-UHFFFAOYSA-N	793853	US20260055102, Example 115	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2V4115S		aid1798066	US20260055102	Guisot, NE; Bhamra, I; Jones, CD; Ryan, J; Andra, MS; Varela Rodriguez, A; Gignoux, C	2/26/2026	7/9/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=793853	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=793853&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170960428	528825316							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730