BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
763013	Cn1ncc2cc(NC3C=CC=C4CN(CC(=O)NCC(F)(F)F)C(=O)C43)ccc21	InChI=1S/C20H20F3N5O2/c1-27-16-6-5-14(7-13(16)8-25-27)26-15-4-2-3-12-9-28(19(30)18(12)15)10-17(29)24-11-20(21,22)23/h2-8,15,18,26H,9-11H2,1H3,(H,24,29)	OTAQSSRNMKPGRZ-UHFFFAOYSA-N	795307	2-[7-[(1-Methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl) acetamide::US20260069571, Example 1	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795307	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795307&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			178423180	528826770							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763014	Cn1ncc2cc(NC3C=CC=C4CN(CC(=O)NCC(F)(F)F)C(=O)C43)ccc21	InChI=1S/C20H20F3N5O2/c1-27-16-6-5-14(7-13(16)8-25-27)26-15-4-2-3-12-9-28(19(30)18(12)15)10-17(29)24-11-20(21,22)23/h2-8,15,18,26H,9-11H2,1H3,(H,24,29)	OTAQSSRNMKPGRZ-UHFFFAOYSA-N	795307	2-[7-[(1-Methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl) acetamide::US20260069571, Example 1	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795307	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795307&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			178423180	528826770							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763015	C[C@H](NC(=O)CN1Cc2cccc(Nc3ccc4c(cnn4C)c3)c2C1=O)C(F)(F)F	InChI=1S/C21H20F3N5O2/c1-12(21(22,23)24)26-18(30)11-29-10-13-4-3-5-16(19(13)20(29)31)27-15-6-7-17-14(8-15)9-25-28(17)2/h3-9,12,27H,10-11H2,1-2H3,(H,26,30)	IBLMYXVNPSVIRJ-UHFFFAOYSA-N	795308	2-[7-[(1-Methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 2	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795308	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795308&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253958	528826771							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763016	C[C@H](NC(=O)CN1Cc2cccc(Nc3ccc4c(cnn4C)c3)c2C1=O)C(F)(F)F	InChI=1S/C21H20F3N5O2/c1-12(21(22,23)24)26-18(30)11-29-10-13-4-3-5-16(19(13)20(29)31)27-15-6-7-17-14(8-15)9-25-28(17)2/h3-9,12,27H,10-11H2,1-2H3,(H,26,30)	IBLMYXVNPSVIRJ-UHFFFAOYSA-N	795308	2-[7-[(1-Methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 2	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795308	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795308&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253958	528826771							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763017	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC3C(F)(F)F)C4)ccc21	InChI=1S/C23H22F3N5O2/c1-29-18-8-7-16(10-15(18)11-27-29)28-17-5-2-4-14-12-30(22(33)21(14)17)13-20(32)31-9-3-6-19(31)23(24,25)26/h2,4-5,7-8,10-11,19,28H,3,6,9,12-13H2,1H3	HWGXDMHHZORENO-UHFFFAOYSA-N	795309	7-[(1-Methylindazol-5-yl)amino]-2-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 3	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795309	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795309&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254104	528826772							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763018	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC3C(F)(F)F)C4)ccc21	InChI=1S/C23H22F3N5O2/c1-29-18-8-7-16(10-15(18)11-27-29)28-17-5-2-4-14-12-30(22(33)21(14)17)13-20(32)31-9-3-6-19(31)23(24,25)26/h2,4-5,7-8,10-11,19,28H,3,6,9,12-13H2,1H3	HWGXDMHHZORENO-UHFFFAOYSA-N	795309	7-[(1-Methylindazol-5-yl)amino]-2-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 3	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795309	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795309&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254104	528826772							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763019	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cnoc3)C4)ccc21	InChI=1S/C21H18N6O3/c1-26-18-6-5-15(7-14(18)8-22-26)24-17-4-2-3-13-10-27(21(29)20(13)17)11-19(28)25-16-9-23-30-12-16/h2-9,12,24H,10-11H2,1H3,(H,25,28)	NMIRFBDAJFNTDP-UHFFFAOYSA-N	795310	N-isoxazol-4-yl-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 4	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795310	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795310&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254190	528826773							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763020	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cnoc3)C4)ccc21	InChI=1S/C21H18N6O3/c1-26-18-6-5-15(7-14(18)8-22-26)24-17-4-2-3-13-10-27(21(29)20(13)17)11-19(28)25-16-9-23-30-12-16/h2-9,12,24H,10-11H2,1H3,(H,25,28)	NMIRFBDAJFNTDP-UHFFFAOYSA-N	795310	N-isoxazol-4-yl-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 4	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795310	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795310&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254190	528826773							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763021	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cccc(C(F)(F)F)c3)C4)ccc21	InChI=1S/C25H20F3N5O2/c1-32-21-9-8-19(10-16(21)12-29-32)30-20-7-2-4-15-13-33(24(35)23(15)20)14-22(34)31-18-6-3-5-17(11-18)25(26,27)28/h2-12,30H,13-14H2,1H3,(H,31,34)	GXTJZMJLAWKINR-UHFFFAOYSA-N	795311	2-{7-[(1-methyl-1H-indazol-5-yl)amino]-1-oxo-2,3-dihydro-1H-isoindol-2-yl}-N-[3-(trifluoromethyl)phenyl]acetamide::US20260069571, Example 5	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795311	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795311&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254152	528826774							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763022	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cccc(C(F)(F)F)c3)C4)ccc21	InChI=1S/C25H20F3N5O2/c1-32-21-9-8-19(10-16(21)12-29-32)30-20-7-2-4-15-13-33(24(35)23(15)20)14-22(34)31-18-6-3-5-17(11-18)25(26,27)28/h2-12,30H,13-14H2,1H3,(H,31,34)	GXTJZMJLAWKINR-UHFFFAOYSA-N	795311	2-{7-[(1-methyl-1H-indazol-5-yl)amino]-1-oxo-2,3-dihydro-1H-isoindol-2-yl}-N-[3-(trifluoromethyl)phenyl]acetamide::US20260069571, Example 5	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795311	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795311&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254152	528826774							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763023	Cc3n[nH]c4cc(Nc2cccc1CN(CC(=O)NCC(F)(F)F)C(=O)c12)ccc34	InChI=1S/C20H18F3N5O2/c1-11-14-6-5-13(7-16(14)27-26-11)25-15-4-2-3-12-8-28(19(30)18(12)15)9-17(29)24-10-20(21,22)23/h2-7,25H,8-10H2,1H3,(H,24,29)(H,26,27)	ASYISBJTBYVORT-UHFFFAOYSA-N	795312	US20260069571, Example 6	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795312	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795312&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253986	528826775							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763024	Cc3n[nH]c4cc(Nc2cccc1CN(CC(=O)NCC(F)(F)F)C(=O)c12)ccc34	InChI=1S/C20H18F3N5O2/c1-11-14-6-5-13(7-16(14)27-26-11)25-15-4-2-3-12-8-28(19(30)18(12)15)9-17(29)24-10-20(21,22)23/h2-7,25H,8-10H2,1H3,(H,24,29)(H,26,27)	ASYISBJTBYVORT-UHFFFAOYSA-N	795312	US20260069571, Example 6	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795312	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795312&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253986	528826775							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763025	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4(C)C)ccc21	InChI=1S/C22H22F3N5O2/c1-21(2)15-5-4-6-16(28-14-7-8-17-13(9-14)10-27-29(17)3)19(15)20(32)30(21)11-18(31)26-12-22(23,24)25/h4-10,28H,11-12H2,1-3H3,(H,26,31)	VGPOYMFSZMERIJ-UHFFFAOYSA-N	795313	2-[1,1-dimethyl-4-[(1-methylindazol-5-yl)amino]-3-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 7	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795313	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795313&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253943	528826776							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763026	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4(C)C)ccc21	InChI=1S/C22H22F3N5O2/c1-21(2)15-5-4-6-16(28-14-7-8-17-13(9-14)10-27-29(17)3)19(15)20(32)30(21)11-18(31)26-12-22(23,24)25/h4-10,28H,11-12H2,1-3H3,(H,26,31)	VGPOYMFSZMERIJ-UHFFFAOYSA-N	795313	2-[1,1-dimethyl-4-[(1-methylindazol-5-yl)amino]-3-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 7	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795313	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795313&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253943	528826776							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763027	CN(c1ccc2c(cnn2C)c1)c1cccc2c1C(=O)N(CC(=O)NCC(F)(F)F)C2	InChI=1S/C21H20F3N5O2/c1-27(15-6-7-16-14(8-15)9-26-28(16)2)17-5-3-4-13-10-29(20(31)19(13)17)11-18(30)25-12-21(22,23)24/h3-9H,10-12H2,1-2H3,(H,25,30)	JJMAYVGPGHCCJM-UHFFFAOYSA-N	795314	2-[7-[methyl-(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 8	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795314	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795314&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254126	528826777							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763028	CN(c1ccc2c(cnn2C)c1)c1cccc2c1C(=O)N(CC(=O)NCC(F)(F)F)C2	InChI=1S/C21H20F3N5O2/c1-27(15-6-7-16-14(8-15)9-26-28(16)2)17-5-3-4-13-10-29(20(31)19(13)17)11-18(30)25-12-21(22,23)24/h3-9H,10-12H2,1-2H3,(H,25,30)	JJMAYVGPGHCCJM-UHFFFAOYSA-N	795314	2-[7-[methyl-(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 8	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795314	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795314&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254126	528826777							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763029	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)cnc21	InChI=1S/C19H17F3N6O2/c1-27-17-12(6-25-27)5-13(7-23-17)26-14-4-2-3-11-8-28(18(30)16(11)14)9-15(29)24-10-19(20,21)22/h2-7,26H,8-10H2,1H3,(H,24,29)	MQIJZXYLTUYVCW-UHFFFAOYSA-N	795315	2-[7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 9	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795315	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795315&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253951	528826778							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763030	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)cnc21	InChI=1S/C19H17F3N6O2/c1-27-17-12(6-25-27)5-13(7-23-17)26-14-4-2-3-11-8-28(18(30)16(11)14)9-15(29)24-10-19(20,21)22/h2-7,26H,8-10H2,1H3,(H,24,29)	MQIJZXYLTUYVCW-UHFFFAOYSA-N	795315	2-[7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 9	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795315	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795315&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253951	528826778							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763031	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cccc(C(C)(C)O)c3)C4)ccc21	InChI=1S/C27H27N5O3/c1-27(2,35)19-7-5-8-20(13-19)30-24(33)16-32-15-17-6-4-9-22(25(17)26(32)34)29-21-10-11-23-18(12-21)14-28-31(23)3/h4-14,29,35H,15-16H2,1-3H3,(H,30,33)	FLUCLRDRSOXHDS-UHFFFAOYSA-N	795317	N-[3-(1-hydroxy-1-methyl-ethyl)phenyl]-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 10	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795317	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795317&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254058	528826780							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763032	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cccc(C(C)(C)O)c3)C4)ccc21	InChI=1S/C27H27N5O3/c1-27(2,35)19-7-5-8-20(13-19)30-24(33)16-32-15-17-6-4-9-22(25(17)26(32)34)29-21-10-11-23-18(12-21)14-28-31(23)3/h4-14,29,35H,15-16H2,1-3H3,(H,30,33)	FLUCLRDRSOXHDS-UHFFFAOYSA-N	795317	N-[3-(1-hydroxy-1-methyl-ethyl)phenyl]-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 10	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795317	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795317&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254058	528826780							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763033	Cc1cc(Nc2cccc3c2C(=O)N(CC(=O)NCC(F)(F)F)C3)cc2cn[nH]c12	InChI=1S/C20H18F3N5O2/c1-11-5-14(6-13-7-25-27-18(11)13)26-15-4-2-3-12-8-28(19(30)17(12)15)9-16(29)24-10-20(21,22)23/h2-7,26H,8-10H2,1H3,(H,24,29)(H,25,27)	XZEZCFCJENRSMH-UHFFFAOYSA-N	795318	2-[7-[(7-methyl-1H-indazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 11	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795318	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795318&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253952	528826781							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763034	Cc1cc(Nc2cccc3c2C(=O)N(CC(=O)NCC(F)(F)F)C3)cc2cn[nH]c12	InChI=1S/C20H18F3N5O2/c1-11-5-14(6-13-7-25-27-18(11)13)26-15-4-2-3-12-8-28(19(30)17(12)15)9-16(29)24-10-20(21,22)23/h2-7,26H,8-10H2,1H3,(H,24,29)(H,25,27)	XZEZCFCJENRSMH-UHFFFAOYSA-N	795318	2-[7-[(7-methyl-1H-indazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 11	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795318	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795318&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253952	528826781							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763035	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC(C(F)(F)F)C3)C4)ccc21	InChI=1S/C24H24F3N5O2/c1-30-20-8-7-18(10-16(20)11-28-30)29-19-6-2-4-15-12-32(23(34)22(15)19)14-21(33)31-9-3-5-17(13-31)24(25,26)27/h2,4,6-8,10-11,17,29H,3,5,9,12-14H2,1H3	ACJMTHPKDAOYAU-UHFFFAOYSA-N	795319	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[3-(trifluoromethyl)-1-piperidyl]ethyl]isoquinolin-1-one::US20260069571, Example 12	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795319	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795319&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254066	528826782							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763036	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC(C(F)(F)F)C3)C4)ccc21	InChI=1S/C24H24F3N5O2/c1-30-20-8-7-18(10-16(20)11-28-30)29-19-6-2-4-15-12-32(23(34)22(15)19)14-21(33)31-9-3-5-17(13-31)24(25,26)27/h2,4,6-8,10-11,17,29H,3,5,9,12-14H2,1H3	ACJMTHPKDAOYAU-UHFFFAOYSA-N	795319	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[3-(trifluoromethyl)-1-piperidyl]ethyl]isoquinolin-1-one::US20260069571, Example 12	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795319	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795319&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254066	528826782							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763037	CN(C)Cc1ccc(NC(=O)CN2Cc3cccc(Nc4ccc5c(cnn5C)c4)c3C2=O)cc1C(F)(F)F	InChI=1S/C28H27F3N6O2/c1-35(2)14-17-7-8-21(12-22(17)28(29,30)31)34-25(38)16-37-15-18-5-4-6-23(26(18)27(37)39)33-20-9-10-24-19(11-20)13-32-36(24)3/h4-13,33H,14-16H2,1-3H3,(H,34,38)	NQGMMJJSXPDDOW-UHFFFAOYSA-N	795320	N-[4-[(dimethylamino)methyl]-3-(trifluoromethyl)phenyl]-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 13	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795320	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795320&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254215	528826783							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763038	CN(C)Cc1ccc(NC(=O)CN2Cc3cccc(Nc4ccc5c(cnn5C)c4)c3C2=O)cc1C(F)(F)F	InChI=1S/C28H27F3N6O2/c1-35(2)14-17-7-8-21(12-22(17)28(29,30)31)34-25(38)16-37-15-18-5-4-6-23(26(18)27(37)39)33-20-9-10-24-19(11-20)13-32-36(24)3/h4-13,33H,14-16H2,1-3H3,(H,34,38)	NQGMMJJSXPDDOW-UHFFFAOYSA-N	795320	N-[4-[(dimethylamino)methyl]-3-(trifluoromethyl)phenyl]-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 13	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795320	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795320&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254215	528826783							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763039	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCCC3C(F)(F)F)C4)ccc21	InChI=1S/C24H24F3N5O2/c1-30-19-9-8-17(11-16(19)12-28-30)29-18-6-4-5-15-13-31(23(34)22(15)18)14-21(33)32-10-3-2-7-20(32)24(25,26)27/h4-6,8-9,11-12,20,29H,2-3,7,10,13-14H2,1H3	RPRRAJSNTKCEAJ-UHFFFAOYSA-N	795321	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)-1-piperidyl]ethyl]isoindolin-1-one::US20260069571, Example 14	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795321	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795321&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254092	528826784							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763040	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCCC3C(F)(F)F)C4)ccc21	InChI=1S/C24H24F3N5O2/c1-30-19-9-8-17(11-16(19)12-28-30)29-18-6-4-5-15-13-31(23(34)22(15)18)14-21(33)32-10-3-2-7-20(32)24(25,26)27/h4-6,8-9,11-12,20,29H,2-3,7,10,13-14H2,1H3	RPRRAJSNTKCEAJ-UHFFFAOYSA-N	795321	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)-1-piperidyl]ethyl]isoindolin-1-one::US20260069571, Example 14	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795321	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795321&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254092	528826784							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763041	CC1c2cccc(Nc3ccc4c(cnn4C)c3)c2C(=O)N1CC(=O)NCC(F)(F)F	InChI=1S/C21H20F3N5O2/c1-12-15-4-3-5-16(27-14-6-7-17-13(8-14)9-26-28(17)2)19(15)20(31)29(12)10-18(30)25-11-21(22,23)24/h3-9,12,27H,10-11H2,1-2H3,(H,25,30)	SRHHJMFBUPPFMN-UHFFFAOYSA-N	795322	2-[1-methyl-4-[(1-methylindazol-5-yl)amino]-3-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 15	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795322	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795322&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254039	528826785							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763042	CC1c2cccc(Nc3ccc4c(cnn4C)c3)c2C(=O)N1CC(=O)NCC(F)(F)F	InChI=1S/C21H20F3N5O2/c1-12-15-4-3-5-16(27-14-6-7-17-13(8-14)9-26-28(17)2)19(15)20(31)29(12)10-18(30)25-11-21(22,23)24/h3-9,12,27H,10-11H2,1-2H3,(H,25,30)	SRHHJMFBUPPFMN-UHFFFAOYSA-N	795322	2-[1-methyl-4-[(1-methylindazol-5-yl)amino]-3-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 15	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795322	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795322&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254039	528826785							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763043	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC[C@@H]3C(F)F)C4)ccc21	InChI=1S/C23H23F2N5O2/c1-28-18-8-7-16(10-15(18)11-26-28)27-17-5-2-4-14-12-29(23(32)21(14)17)13-20(31)30-9-3-6-19(30)22(24)25/h2,4-5,7-8,10-11,19,22,27H,3,6,9,12-13H2,1H3	BCMKXOQRGYMKLD-UHFFFAOYSA-N	795323	2-[2-[(2S)-(difluoromethyl)pyrrolidin-1-yl]-2-oxo-ethyl]-7-[(1-methylindazol-5-yl)amino]isoindolin-1-one::US20260069571, Example 16	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795323	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795323&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			178423181	528826786							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763044	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC[C@@H]3C(F)F)C4)ccc21	InChI=1S/C23H23F2N5O2/c1-28-18-8-7-16(10-15(18)11-26-28)27-17-5-2-4-14-12-29(23(32)21(14)17)13-20(31)30-9-3-6-19(30)22(24)25/h2,4-5,7-8,10-11,19,22,27H,3,6,9,12-13H2,1H3	BCMKXOQRGYMKLD-UHFFFAOYSA-N	795323	2-[2-[(2S)-(difluoromethyl)pyrrolidin-1-yl]-2-oxo-ethyl]-7-[(1-methylindazol-5-yl)amino]isoindolin-1-one::US20260069571, Example 16	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795323	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795323&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			178423181	528826786							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763045	Cn5ncc4cc(Nc3cccc2CN(CC(=O)N1CCC[C@@H]1C(F)F)C(=O)c23)ccc45	InChI=1S/C23H23F2N5O2/c1-28-18-8-7-16(10-15(18)11-26-28)27-17-5-2-4-14-12-29(23(32)21(14)17)13-20(31)30-9-3-6-19(30)22(24)25/h2,4-5,7-8,10-11,19,22,27H,3,6,9,12-13H2,1H3	BCMKXOQRGYMKLD-UHFFFAOYSA-N	795324	2-[2-[(2S)-(fluoromethyl)pyrrolidin-1-yl]-2-oxo-ethyl]-7-[(1-methylindazol-5-yl)amino]isoindolin-1-one::US20260069571, Example 17	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795324	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795324&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			178423181	528826787							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763046	Cn5ncc4cc(Nc3cccc2CN(CC(=O)N1CCC[C@@H]1C(F)F)C(=O)c23)ccc45	InChI=1S/C23H23F2N5O2/c1-28-18-8-7-16(10-15(18)11-26-28)27-17-5-2-4-14-12-29(23(32)21(14)17)13-20(31)30-9-3-6-19(30)22(24)25/h2,4-5,7-8,10-11,19,22,27H,3,6,9,12-13H2,1H3	BCMKXOQRGYMKLD-UHFFFAOYSA-N	795324	2-[2-[(2S)-(fluoromethyl)pyrrolidin-1-yl]-2-oxo-ethyl]-7-[(1-methylindazol-5-yl)amino]isoindolin-1-one::US20260069571, Example 17	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795324	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795324&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			178423181	528826787							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763047	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CC(C(F)(F)F)C3)C4)ccc21	InChI=1S/C22H20F3N5O2/c1-28-18-6-5-16(7-14(18)8-26-28)27-17-4-2-3-13-9-30(21(32)20(13)17)12-19(31)29-10-15(11-29)22(23,24)25/h2-8,15,27H,9-12H2,1H3	LQYYLBZSVMJCDN-UHFFFAOYSA-N	795325	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[3-(trifluoromethyl)73zetidine-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 18	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795325	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795325&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254052	528826788							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763048	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CC(C(F)(F)F)C3)C4)ccc21	InChI=1S/C22H20F3N5O2/c1-28-18-6-5-16(7-14(18)8-26-28)27-17-4-2-3-13-9-30(21(32)20(13)17)12-19(31)29-10-15(11-29)22(23,24)25/h2-8,15,27H,9-12H2,1H3	LQYYLBZSVMJCDN-UHFFFAOYSA-N	795325	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[3-(trifluoromethyl)73zetidine-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 18	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795325	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795325&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254052	528826788							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763049	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CC(F)(F)C3)C4)ccc21	InChI=1S/C21H19F2N5O2/c1-26-17-6-5-15(7-14(17)8-24-26)25-16-4-2-3-13-9-27(20(30)19(13)16)10-18(29)28-11-21(22,23)12-28/h2-8,25H,9-12H2,1H3	ZUBOYHNMIPDRID-UHFFFAOYSA-N	795326	2-[2-(3,3-difluoroazetidin-1-yl)-2-oxo-ethyl]-7-[(1-methylindazol-5-yl)amino]isoindolin-1-one::US20260069571, Example 19	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795326	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795326&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254003	528826789							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763050	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CC(F)(F)C3)C4)ccc21	InChI=1S/C21H19F2N5O2/c1-26-17-6-5-15(7-14(17)8-24-26)25-16-4-2-3-13-9-27(20(30)19(13)16)10-18(29)28-11-21(22,23)12-28/h2-8,25H,9-12H2,1H3	ZUBOYHNMIPDRID-UHFFFAOYSA-N	795326	2-[2-(3,3-difluoroazetidin-1-yl)-2-oxo-ethyl]-7-[(1-methylindazol-5-yl)amino]isoindolin-1-one::US20260069571, Example 19	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795326	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795326&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254003	528826789							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763051	CN(C)Cc1cc(NC(=O)CN2Cc3cccc(Nc4ccc5c(cnn5C)c4)c3C2=O)cc(C(F)(F)F)c1	InChI=1S/C28H27F3N6O2/c1-35(2)14-17-9-20(28(29,30)31)12-22(10-17)34-25(38)16-37-15-18-5-4-6-23(26(18)27(37)39)33-21-7-8-24-19(11-21)13-32-36(24)3/h4-13,33H,14-16H2,1-3H3,(H,34,38)	IVJNVTMQUPPZSB-UHFFFAOYSA-N	795327	N-[3-[(dimethylamino)methyl]-5-(trifluoromethyl)phenyl]-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 20	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795327	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795327&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253941	528826790							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763052	CN(C)Cc1cc(NC(=O)CN2Cc3cccc(Nc4ccc5c(cnn5C)c4)c3C2=O)cc(C(F)(F)F)c1	InChI=1S/C28H27F3N6O2/c1-35(2)14-17-9-20(28(29,30)31)12-22(10-17)34-25(38)16-37-15-18-5-4-6-23(26(18)27(37)39)33-21-7-8-24-19(11-21)13-32-36(24)3/h4-13,33H,14-16H2,1-3H3,(H,34,38)	IVJNVTMQUPPZSB-UHFFFAOYSA-N	795327	N-[3-[(dimethylamino)methyl]-5-(trifluoromethyl)phenyl]-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 20	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795327	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795327&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253941	528826790							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763053	O=C(CN1Cc2cccc(Nc3ccc4[nH]ncc4c3)c2C1=O)NCC(F)(F)F	InChI=1S/C19H16F3N5O2/c20-19(21,22)10-23-16(28)9-27-8-11-2-1-3-15(17(11)18(27)29)25-13-4-5-14-12(6-13)7-24-26-14/h1-7,25H,8-10H2,(H,23,28)(H,24,26)	WWMXZLUXLWULBF-UHFFFAOYSA-N	795328	2-[7-(1H-indazol-5-ylamino)-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 21	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795328	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795328&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254023	528826791							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763054	O=C(CN1Cc2cccc(Nc3ccc4[nH]ncc4c3)c2C1=O)NCC(F)(F)F	InChI=1S/C19H16F3N5O2/c20-19(21,22)10-23-16(28)9-27-8-11-2-1-3-15(17(11)18(27)29)25-13-4-5-14-12(6-13)7-24-26-14/h1-7,25H,8-10H2,(H,23,28)(H,24,26)	WWMXZLUXLWULBF-UHFFFAOYSA-N	795328	2-[7-(1H-indazol-5-ylamino)-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 21	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795328	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795328&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254023	528826791							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763055	O=C(CN1Cc2cccc(Nc3cnc4[nH]ncc4c3)c2C1=O)NCC(F)(F)F	InChI=1S/C18H15F3N6O2/c19-18(20,21)9-23-14(28)8-27-7-10-2-1-3-13(15(10)17(27)29)25-12-4-11-5-24-26-16(11)22-6-12/h1-6,25H,7-9H2,(H,23,28)(H,22,24,26)	AZYZRAXQHLXILO-UHFFFAOYSA-N	795329	5-ylamino)isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 22	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795329	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795329&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254069	528826792							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763056	O=C(CN1Cc2cccc(Nc3cnc4[nH]ncc4c3)c2C1=O)NCC(F)(F)F	InChI=1S/C18H15F3N6O2/c19-18(20,21)9-23-14(28)8-27-7-10-2-1-3-13(15(10)17(27)29)25-12-4-11-5-24-26-16(11)22-6-12/h1-6,25H,7-9H2,(H,23,28)(H,22,24,26)	AZYZRAXQHLXILO-UHFFFAOYSA-N	795329	5-ylamino)isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 22	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795329	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795329&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254069	528826792							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763057	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cccc(C(C)(C)N)c3)C4)ccc21	InChI=1S/C27H28N6O2/c1-27(2,28)19-7-5-8-20(13-19)31-24(34)16-33-15-17-6-4-9-22(25(17)26(33)35)30-21-10-11-23-18(12-21)14-29-32(23)3/h4-14,30H,15-16,28H2,1-3H3,(H,31,34)	HRHMUHDAJYYJHT-UHFFFAOYSA-N	795330	N-[3-(1-amino-1-methyl-ethyl)phenyl]-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 23	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795330	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795330&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169815761	528826793							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763058	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cccc(C(C)(C)N)c3)C4)ccc21	InChI=1S/C27H28N6O2/c1-27(2,28)19-7-5-8-20(13-19)31-24(34)16-33-15-17-6-4-9-22(25(17)26(33)35)30-21-10-11-23-18(12-21)14-29-32(23)3/h4-14,30H,15-16,28H2,1-3H3,(H,31,34)	HRHMUHDAJYYJHT-UHFFFAOYSA-N	795330	N-[3-(1-amino-1-methyl-ethyl)phenyl]-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 23	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795330	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795330&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169815761	528826793							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763059	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NC3CC3(F)F)C4)ccc21	InChI=1S/C21H19F2N5O2/c1-27-16-6-5-14(7-13(16)9-24-27)25-15-4-2-3-12-10-28(20(30)19(12)15)11-18(29)26-17-8-21(17,22)23/h2-7,9,17,25H,8,10-11H2,1H3,(H,26,29)	OVAKXVDLLFZQOP-UHFFFAOYSA-N	795331	N-(2,2-difluorocyclopropyl)-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 24	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795331	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795331&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254044	528826794							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763060	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NC3CC3(F)F)C4)ccc21	InChI=1S/C21H19F2N5O2/c1-27-16-6-5-14(7-13(16)9-24-27)25-15-4-2-3-12-10-28(20(30)19(12)15)11-18(29)26-17-8-21(17,22)23/h2-7,9,17,25H,8,10-11H2,1H3,(H,26,29)	OVAKXVDLLFZQOP-UHFFFAOYSA-N	795331	N-(2,2-difluorocyclopropyl)-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 24	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795331	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795331&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254044	528826794							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763061	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOC(C(F)(F)F)C3)C4)ccc21	InChI=1S/C23H22F3N5O3/c1-29-18-6-5-16(9-15(18)10-27-29)28-17-4-2-3-14-11-31(22(33)21(14)17)13-20(32)30-7-8-34-19(12-30)23(24,25)26/h2-6,9-10,19,28H,7-8,11-13H2,1H3	BFUXSJZPCKANRV-UHFFFAOYSA-N	795332	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[2-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 26	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795332	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795332&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254087	528826795							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763062	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOC(C(F)(F)F)C3)C4)ccc21	InChI=1S/C23H22F3N5O3/c1-29-18-6-5-16(9-15(18)10-27-29)28-17-4-2-3-14-11-31(22(33)21(14)17)13-20(32)30-7-8-34-19(12-30)23(24,25)26/h2-6,9-10,19,28H,7-8,11-13H2,1H3	BFUXSJZPCKANRV-UHFFFAOYSA-N	795332	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[2-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 26	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795332	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795332&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254087	528826795							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763063	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)cc(Cl)c21	InChI=1S/C20H17ClF3N5O2/c1-28-18-12(7-26-28)5-13(6-14(18)21)27-15-4-2-3-11-8-29(19(31)17(11)15)9-16(30)25-10-20(22,23)24/h2-7,27H,8-10H2,1H3,(H,25,30)	GELAQUQZUDUWFW-UHFFFAOYSA-N	795333	2-[7-[(7-chloro-1-methyl-indazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 27	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795333	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795333&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254078	528826796							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763064	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)cc(Cl)c21	InChI=1S/C20H17ClF3N5O2/c1-28-18-12(7-26-28)5-13(6-14(18)21)27-15-4-2-3-11-8-29(19(31)17(11)15)9-16(30)25-10-20(22,23)24/h2-7,27H,8-10H2,1H3,(H,25,30)	GELAQUQZUDUWFW-UHFFFAOYSA-N	795333	2-[7-[(7-chloro-1-methyl-indazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 27	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795333	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795333&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254078	528826796							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763065	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N[C@@H](C)C(F)(F)F)C4)ccc12	InChI=1S/C21H20F3N5O2/c1-11-15-7-6-14(8-17(15)28-27-11)26-16-5-3-4-13-9-29(20(31)19(13)16)10-18(30)25-12(2)21(22,23)24/h3-8,12,26H,9-10H2,1-2H3,(H,25,30)(H,27,28)	RCHBHJXTCPQZPE-UHFFFAOYSA-N	795334	2-[7-[(3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 28	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795334	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795334&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254138	528826797							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763066	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N[C@@H](C)C(F)(F)F)C4)ccc12	InChI=1S/C21H20F3N5O2/c1-11-15-7-6-14(8-17(15)28-27-11)26-16-5-3-4-13-9-29(20(31)19(13)16)10-18(30)25-12(2)21(22,23)24/h3-8,12,26H,9-10H2,1-2H3,(H,25,30)(H,27,28)	RCHBHJXTCPQZPE-UHFFFAOYSA-N	795334	2-[7-[(3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 28	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795334	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795334&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254138	528826797							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763067	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC3C(F)(F)F)C4)ccc12	InChI=1S/C23H22F3N5O2/c1-13-16-8-7-15(10-18(16)29-28-13)27-17-5-2-4-14-11-30(22(33)21(14)17)12-20(32)31-9-3-6-19(31)23(24,25)26/h2,4-5,7-8,10,19,27H,3,6,9,11-12H2,1H3,(H,28,29)	PVMTUSYVHGBQIE-UHFFFAOYSA-N	795335	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)77yrrolidine-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 29	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795335	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795335&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254037	528826798							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763068	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC3C(F)(F)F)C4)ccc12	InChI=1S/C23H22F3N5O2/c1-13-16-8-7-15(10-18(16)29-28-13)27-17-5-2-4-14-11-30(22(33)21(14)17)12-20(32)31-9-3-6-19(31)23(24,25)26/h2,4-5,7-8,10,19,27H,3,6,9,11-12H2,1H3,(H,28,29)	PVMTUSYVHGBQIE-UHFFFAOYSA-N	795335	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)77yrrolidine-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 29	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795335	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795335&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254037	528826798							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763069	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)cnc12	InChI=1S/C19H17F3N6O2/c1-10-17-14(27-26-10)5-12(6-23-17)25-13-4-2-3-11-7-28(18(30)16(11)13)8-15(29)24-9-19(20,21)22/h2-6,25H,7-9H2,1H3,(H,24,29)(H,26,27)	PKZJCPAMRQQYKR-UHFFFAOYSA-N	795336	2-[7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 30	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795336	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795336&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253957	528826799							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763070	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)cnc12	InChI=1S/C19H17F3N6O2/c1-10-17-14(27-26-10)5-12(6-23-17)25-13-4-2-3-11-7-28(18(30)16(11)13)8-15(29)24-9-19(20,21)22/h2-6,25H,7-9H2,1H3,(H,24,29)(H,26,27)	PKZJCPAMRQQYKR-UHFFFAOYSA-N	795336	2-[7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 30	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795336	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795336&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253957	528826799							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763071	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOCC3C(F)(F)F)C4)ccc21	InChI=1S/C23H22F3N5O3/c1-29-18-6-5-16(9-15(18)10-27-29)28-17-4-2-3-14-11-30(22(33)21(14)17)12-20(32)31-7-8-34-13-19(31)23(24,25)26/h2-6,9-10,19,28H,7-8,11-13H2,1H3	SJUDUPWPHNLQHG-UHFFFAOYSA-N	795337	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[3-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 31	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795337	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795337&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254195	528826800							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763072	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOCC3C(F)(F)F)C4)ccc21	InChI=1S/C23H22F3N5O3/c1-29-18-6-5-16(9-15(18)10-27-29)28-17-4-2-3-14-11-30(22(33)21(14)17)12-20(32)31-7-8-34-13-19(31)23(24,25)26/h2-6,9-10,19,28H,7-8,11-13H2,1H3	SJUDUPWPHNLQHG-UHFFFAOYSA-N	795337	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[3-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 31	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795337	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795337&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254195	528826800							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763073	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC(C(F)(F)F)C3)C4)ccc12	InChI=1S/C24H24F3N5O2/c1-14-18-8-7-17(10-20(18)30-29-14)28-19-6-2-4-15-11-32(23(34)22(15)19)13-21(33)31-9-3-5-16(12-31)24(25,26)27/h2,4,6-8,10,16,28H,3,5,9,11-13H2,1H3,(H,29,30)	XZZIULFNOJQGRM-UHFFFAOYSA-N	795338	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[3-(trifluoromethyl)-1-piperidyl]ethyl]isoindolin-1-one::US20260069571, Example 32	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795338	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795338&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253938	528826801							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763074	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC(C(F)(F)F)C3)C4)ccc12	InChI=1S/C24H24F3N5O2/c1-14-18-8-7-17(10-20(18)30-29-14)28-19-6-2-4-15-11-32(23(34)22(15)19)13-21(33)31-9-3-5-16(12-31)24(25,26)27/h2,4,6-8,10,16,28H,3,5,9,11-13H2,1H3,(H,29,30)	XZZIULFNOJQGRM-UHFFFAOYSA-N	795338	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[3-(trifluoromethyl)-1-piperidyl]ethyl]isoindolin-1-one::US20260069571, Example 32	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795338	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795338&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253938	528826801							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763075	Cc4n[nH]c5cc(Nc3cccc2CN(CC(=O)N1CCC[C@H]1CF)C(=O)c23)ccc45	InChI=1S/C24H26FN5O2/c1-14(25)21-7-4-10-30(21)22(31)13-29-12-16-5-3-6-19(23(16)24(29)32)26-17-8-9-18-15(2)27-28-20(18)11-17/h3,5-6,8-9,11,14,21,26H,4,7,10,12-13H2,1-2H3,(H,27,28)	MPSPWGKILMYXSP-UHFFFAOYSA-N	795339	2-[2-[(2S)-(fluoromethyl)pyrrolidin-1-yl]-2-oxo-ethyl]-7-[(3-methyl-1H-indazol-6-yl)amino]isoindolin-1-one::US20260069571, Example 33	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795339	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795339&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			177897599	528826802							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763076	Cc4n[nH]c5cc(Nc3cccc2CN(CC(=O)N1CCC[C@H]1CF)C(=O)c23)ccc45	InChI=1S/C24H26FN5O2/c1-14(25)21-7-4-10-30(21)22(31)13-29-12-16-5-3-6-19(23(16)24(29)32)26-17-8-9-18-15(2)27-28-20(18)11-17/h3,5-6,8-9,11,14,21,26H,4,7,10,12-13H2,1-2H3,(H,27,28)	MPSPWGKILMYXSP-UHFFFAOYSA-N	795339	2-[2-[(2S)-(fluoromethyl)pyrrolidin-1-yl]-2-oxo-ethyl]-7-[(3-methyl-1H-indazol-6-yl)amino]isoindolin-1-one::US20260069571, Example 33	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795339	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795339&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			177897599	528826802							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763077	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CC(C(F)(F)F)C3)C4)ccc12	InChI=1S/C22H20F3N5O2/c1-12-16-6-5-15(7-18(16)28-27-12)26-17-4-2-3-13-8-30(21(32)20(13)17)11-19(31)29-9-14(10-29)22(23,24)25/h2-7,14,26H,8-11H2,1H3,(H,27,28)	VKECNWANMZPMHD-UHFFFAOYSA-N	795340	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[3-(trifluoromethyl)azetidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 34	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795340	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795340&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254077	528826803							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763078	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CC(C(F)(F)F)C3)C4)ccc12	InChI=1S/C22H20F3N5O2/c1-12-16-6-5-15(7-18(16)28-27-12)26-17-4-2-3-13-8-30(21(32)20(13)17)11-19(31)29-9-14(10-29)22(23,24)25/h2-7,14,26H,8-11H2,1H3,(H,27,28)	VKECNWANMZPMHD-UHFFFAOYSA-N	795340	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[3-(trifluoromethyl)azetidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 34	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795340	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795340&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254077	528826803							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763079	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)NC3CC3(F)F)C4)ccc12	InChI=1S/C21H19F2N5O2/c1-11-14-6-5-13(7-16(14)27-26-11)24-15-4-2-3-12-9-28(20(30)19(12)15)10-18(29)25-17-8-21(17,22)23/h2-7,17,24H,8-10H2,1H3,(H,25,29)(H,26,27)	VVVSFVAKHCMYRT-UHFFFAOYSA-N	795341	N-(2,2-difluorocyclopropyl)-2-[7-[(3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 36	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795341	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795341&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254208	528826804							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763080	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)NC3CC3(F)F)C4)ccc12	InChI=1S/C21H19F2N5O2/c1-11-14-6-5-13(7-16(14)27-26-11)24-15-4-2-3-12-9-28(20(30)19(12)15)10-18(29)25-17-8-21(17,22)23/h2-7,17,24H,8-10H2,1H3,(H,25,29)(H,26,27)	VVVSFVAKHCMYRT-UHFFFAOYSA-N	795341	N-(2,2-difluorocyclopropyl)-2-[7-[(3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 36	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795341	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795341&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254208	528826804							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763081	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3ccc(CN(C)C)c(C(F)(F)F)c3)C4)ccc12	InChI=1S/C28H27F3N6O2/c1-16-21-10-9-20(12-24(21)35-34-16)32-23-6-4-5-18-14-37(27(39)26(18)23)15-25(38)33-19-8-7-17(13-36(2)3)22(11-19)28(29,30)31/h4-12,32H,13-15H2,1-3H3,(H,33,38)(H,34,35)	WMADWQUIUVDXEW-UHFFFAOYSA-N	795342	N-[4-[(dimethylamino)methyl]-3-(trifluoromethyl)phenyl]-2-[7-[(3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 37	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795342	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795342&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254147	528826805							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763082	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3ccc(CN(C)C)c(C(F)(F)F)c3)C4)ccc12	InChI=1S/C28H27F3N6O2/c1-16-21-10-9-20(12-24(21)35-34-16)32-23-6-4-5-18-14-37(27(39)26(18)23)15-25(38)33-19-8-7-17(13-36(2)3)22(11-19)28(29,30)31/h4-12,32H,13-15H2,1-3H3,(H,33,38)(H,34,35)	WMADWQUIUVDXEW-UHFFFAOYSA-N	795342	N-[4-[(dimethylamino)methyl]-3-(trifluoromethyl)phenyl]-2-[7-[(3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 37	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795342	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795342&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254147	528826805							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763083	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOC(C(F)(F)F)C3)C4)ccc12	InChI=1S/C23H22F3N5O3/c1-13-16-6-5-15(9-18(16)29-28-13)27-17-4-2-3-14-10-31(22(33)21(14)17)12-20(32)30-7-8-34-19(11-30)23(24,25)26/h2-6,9,19,27H,7-8,10-12H2,1H3,(H,28,29)	DSFFNADAWSDSIG-UHFFFAOYSA-N	795343	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[2-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 38	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795343	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795343&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253923	528826806							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763084	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOC(C(F)(F)F)C3)C4)ccc12	InChI=1S/C23H22F3N5O3/c1-13-16-6-5-15(9-18(16)29-28-13)27-17-4-2-3-14-10-31(22(33)21(14)17)12-20(32)30-7-8-34-19(11-30)23(24,25)26/h2-6,9,19,27H,7-8,10-12H2,1H3,(H,28,29)	DSFFNADAWSDSIG-UHFFFAOYSA-N	795343	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[2-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 38	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795343	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795343&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253923	528826806							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763085	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cc(CN(C)C)cc(C(F)(F)F)c3)C4)ccc12	InChI=1S/C28H27F3N6O2/c1-16-22-8-7-20(12-24(22)35-34-16)32-23-6-4-5-18-14-37(27(39)26(18)23)15-25(38)33-21-10-17(13-36(2)3)9-19(11-21)28(29,30)31/h4-12,32H,13-15H2,1-3H3,(H,33,38)(H,34,35)	ATJKVSKBDPKJRD-UHFFFAOYSA-N	795344	N-[3-[(dimethylamino)methyl]-5-(trifluoromethyl)phenyl]-2-[7-[(3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 39	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795344&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254204	528826807							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763086	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cc(CN(C)C)cc(C(F)(F)F)c3)C4)ccc12	InChI=1S/C28H27F3N6O2/c1-16-22-8-7-20(12-24(22)35-34-16)32-23-6-4-5-18-14-37(27(39)26(18)23)15-25(38)33-21-10-17(13-36(2)3)9-19(11-21)28(29,30)31/h4-12,32H,13-15H2,1-3H3,(H,33,38)(H,34,35)	ATJKVSKBDPKJRD-UHFFFAOYSA-N	795344	N-[3-[(dimethylamino)methyl]-5-(trifluoromethyl)phenyl]-2-[7-[(3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 39	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795344&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254204	528826807							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763087	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cnoc3)C4)ccc12	InChI=1S/C21H18N6O3/c1-12-16-6-5-14(7-18(16)26-25-12)23-17-4-2-3-13-9-27(21(29)20(13)17)10-19(28)24-15-8-22-30-11-15/h2-8,11,23H,9-10H2,1H3,(H,24,28)(H,25,26)	LNIZRDJJFFVWHU-UHFFFAOYSA-N	795345	N-isoxazol-4-yl-2-[7-[(3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 40	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795345&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254041	528826808							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763088	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cnoc3)C4)ccc12	InChI=1S/C21H18N6O3/c1-12-16-6-5-14(7-18(16)26-25-12)23-17-4-2-3-13-9-27(21(29)20(13)17)10-19(28)24-15-8-22-30-11-15/h2-8,11,23H,9-10H2,1H3,(H,24,28)(H,25,26)	LNIZRDJJFFVWHU-UHFFFAOYSA-N	795345	N-isoxazol-4-yl-2-[7-[(3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 40	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795345&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254041	528826808							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763089	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC[C@H]3C(F)F)C4)ccc12	InChI=1S/C23H23F2N5O2/c1-13-16-8-7-15(10-18(16)28-27-13)26-17-5-2-4-14-11-29(23(32)21(14)17)12-20(31)30-9-3-6-19(30)22(24)25/h2,4-5,7-8,10,19,22,26H,3,6,9,11-12H2,1H3,(H,27,28)	PRHGJRRFIHRBIM-UHFFFAOYSA-N	795346	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[(2S)-(difluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 41	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795346	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795346&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			177897600	528826809							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763090	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC[C@H]3C(F)F)C4)ccc12	InChI=1S/C23H23F2N5O2/c1-13-16-8-7-15(10-18(16)28-27-13)26-17-5-2-4-14-11-29(23(32)21(14)17)12-20(31)30-9-3-6-19(30)22(24)25/h2,4-5,7-8,10,19,22,26H,3,6,9,11-12H2,1H3,(H,27,28)	PRHGJRRFIHRBIM-UHFFFAOYSA-N	795346	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[(2S)-(difluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 41	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795346	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795346&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			177897600	528826809							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763091	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCCC3C(F)(F)F)C4)ccc12	InChI=1S/C24H24F3N5O2/c1-14-17-9-8-16(11-19(17)30-29-14)28-18-6-4-5-15-12-31(23(34)22(15)18)13-21(33)32-10-3-2-7-20(32)24(25,26)27/h4-6,8-9,11,20,28H,2-3,7,10,12-13H2,1H3,(H,29,30)	JIZQLDIMFTVVIW-UHFFFAOYSA-N	795347	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)-1-piperidyl]ethyl]isoindolin-1-one::US20260069571, Example 42	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795347&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169815929	528826810							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763092	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCCC3C(F)(F)F)C4)ccc12	InChI=1S/C24H24F3N5O2/c1-14-17-9-8-16(11-19(17)30-29-14)28-18-6-4-5-15-12-31(23(34)22(15)18)13-21(33)32-10-3-2-7-20(32)24(25,26)27/h4-6,8-9,11,20,28H,2-3,7,10,12-13H2,1H3,(H,29,30)	JIZQLDIMFTVVIW-UHFFFAOYSA-N	795347	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)-1-piperidyl]ethyl]isoindolin-1-one::US20260069571, Example 42	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795347&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169815929	528826810							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763093	CN(CC(F)(F)F)C(=O)CN1Cc2cccc(Nc3ccc4c(cnn4C)c3)c2C1=O	InChI=1S/C21H20F3N5O2/c1-27(12-21(22,23)24)18(30)11-29-10-13-4-3-5-16(19(13)20(29)31)26-15-6-7-17-14(8-15)9-25-28(17)2/h3-9,26H,10-12H2,1-2H3	GPSHBDFIJPPYDZ-UHFFFAOYSA-N	795348	N-methyl-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 43	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795348&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253983	528826811							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763094	CN(CC(F)(F)F)C(=O)CN1Cc2cccc(Nc3ccc4c(cnn4C)c3)c2C1=O	InChI=1S/C21H20F3N5O2/c1-27(12-21(22,23)24)18(30)11-29-10-13-4-3-5-16(19(13)20(29)31)26-15-6-7-17-14(8-15)9-25-28(17)2/h3-9,26H,10-12H2,1-2H3	GPSHBDFIJPPYDZ-UHFFFAOYSA-N	795348	N-methyl-2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 43	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795348&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253983	528826811							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763095	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOCC3C(F)(F)F)C4)ccc21	InChI=1S/C23H22F3N5O3/c1-29-18-6-5-16(9-15(18)10-27-29)28-17-4-2-3-14-11-30(22(33)21(14)17)12-20(32)31-7-8-34-13-19(31)23(24,25)26/h2-6,9-10,19,28H,7-8,11-13H2,1H3	SJUDUPWPHNLQHG-UHFFFAOYSA-N	795349	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[(3S)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 44	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795349&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254160	528826812							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763096	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOCC3C(F)(F)F)C4)ccc21	InChI=1S/C23H22F3N5O3/c1-29-18-6-5-16(9-15(18)10-27-29)28-17-4-2-3-14-11-30(22(33)21(14)17)12-20(32)31-7-8-34-13-19(31)23(24,25)26/h2-6,9-10,19,28H,7-8,11-13H2,1H3	SJUDUPWPHNLQHG-UHFFFAOYSA-N	795349	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[(3S)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 44	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795349&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254160	528826812							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763097	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOCC3C(F)(F)F)C4)ccc21	InChI=1S/C23H22F3N5O3/c1-29-18-6-5-16(9-15(18)10-27-29)28-17-4-2-3-14-11-30(22(33)21(14)17)12-20(32)31-7-8-34-13-19(31)23(24,25)26/h2-6,9-10,19,28H,7-8,11-13H2,1H3	SJUDUPWPHNLQHG-UHFFFAOYSA-N	795350	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[(3R)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 45	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795350&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169815955	528826813							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763098	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOCC3C(F)(F)F)C4)ccc21	InChI=1S/C23H22F3N5O3/c1-29-18-6-5-16(9-15(18)10-27-29)28-17-4-2-3-14-11-30(22(33)21(14)17)12-20(32)31-7-8-34-13-19(31)23(24,25)26/h2-6,9-10,19,28H,7-8,11-13H2,1H3	SJUDUPWPHNLQHG-UHFFFAOYSA-N	795350	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[(3R)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 45	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795350&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169815955	528826813							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763099	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N(C)CC(F)(F)F)C4)ccc12	InChI=1S/C21H20F3N5O2/c1-12-15-7-6-14(8-17(15)27-26-12)25-16-5-3-4-13-9-29(20(31)19(13)16)10-18(30)28(2)11-21(22,23)24/h3-8,25H,9-11H2,1-2H3,(H,26,27)	TXBQVRIXLZZWCA-UHFFFAOYSA-N	795351	N-methyl-2-[7-[(3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 46	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795351	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795351&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254151	528826814							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763100	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N(C)CC(F)(F)F)C4)ccc12	InChI=1S/C21H20F3N5O2/c1-12-15-7-6-14(8-17(15)27-26-12)25-16-5-3-4-13-9-29(20(31)19(13)16)10-18(30)28(2)11-21(22,23)24/h3-8,25H,9-11H2,1-2H3,(H,26,27)	TXBQVRIXLZZWCA-UHFFFAOYSA-N	795351	N-methyl-2-[7-[(3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 46	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795351	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795351&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254151	528826814							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763101	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCO[C@@H](C(F)(F)F)C3)C4)ccc12	InChI=1S/C23H22F3N5O3/c1-13-16-6-5-15(9-18(16)29-28-13)27-17-4-2-3-14-10-31(22(33)21(14)17)12-20(32)30-7-8-34-19(11-30)23(24,25)26/h2-6,9,19,27H,7-8,10-12H2,1H3,(H,28,29)	DSFFNADAWSDSIG-UHFFFAOYSA-N	795352	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[(2R)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 47	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795352	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795352&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			170176739	528826815							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763102	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCO[C@@H](C(F)(F)F)C3)C4)ccc12	InChI=1S/C23H22F3N5O3/c1-13-16-6-5-15(9-18(16)29-28-13)27-17-4-2-3-14-10-31(22(33)21(14)17)12-20(32)30-7-8-34-19(11-30)23(24,25)26/h2-6,9,19,27H,7-8,10-12H2,1H3,(H,28,29)	DSFFNADAWSDSIG-UHFFFAOYSA-N	795352	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[(2R)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 47	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795352	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795352&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			170176739	528826815							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763103	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCO[C@H](C(F)(F)F)C3)C4)ccc12	InChI=1S/C23H22F3N5O3/c1-13-16-6-5-15(9-18(16)29-28-13)27-17-4-2-3-14-10-31(22(33)21(14)17)12-20(32)30-7-8-34-19(11-30)23(24,25)26/h2-6,9,19,27H,7-8,10-12H2,1H3,(H,28,29)	DSFFNADAWSDSIG-UHFFFAOYSA-N	795353	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 48	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795353	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795353&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169816048	528826816							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763104	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCO[C@H](C(F)(F)F)C3)C4)ccc12	InChI=1S/C23H22F3N5O3/c1-13-16-6-5-15(9-18(16)29-28-13)27-17-4-2-3-14-10-31(22(33)21(14)17)12-20(32)30-7-8-34-19(11-30)23(24,25)26/h2-6,9,19,27H,7-8,10-12H2,1H3,(H,28,29)	DSFFNADAWSDSIG-UHFFFAOYSA-N	795353	7-[(3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 48	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795353	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795353&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169816048	528826816							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763105	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NC(C)(C)C(F)(F)F)C4)ccc21	InChI=1S/C22H22F3N5O2/c1-21(2,22(23,24)25)28-18(31)12-30-11-13-5-4-6-16(19(13)20(30)32)27-15-7-8-17-14(9-15)10-26-29(17)3/h4-10,27H,11-12H2,1-3H3,(H,28,31)	XEGSBABUSFQXRO-UHFFFAOYSA-N	795354	2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoro-1,1-dimethyl-ethyl)acetamide::US20260069571, Example 49	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795354	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795354&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254010	528826817							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763106	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NC(C)(C)C(F)(F)F)C4)ccc21	InChI=1S/C22H22F3N5O2/c1-21(2,22(23,24)25)28-18(31)12-30-11-13-5-4-6-16(19(13)20(30)32)27-15-7-8-17-14(9-15)10-26-29(17)3/h4-10,27H,11-12H2,1-3H3,(H,28,31)	XEGSBABUSFQXRO-UHFFFAOYSA-N	795354	2-[7-[(1-methylindazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoro-1,1-dimethyl-ethyl)acetamide::US20260069571, Example 49	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795354	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795354&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254010	528826817							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763107	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC3C(F)(F)F)C4)ccc21	InChI=1S/C22H20F3N5O2/c1-28-17-6-5-15(9-14(17)10-26-28)27-16-4-2-3-13-11-29(21(32)20(13)16)12-19(31)30-8-7-18(30)22(23,24)25/h2-6,9-10,18,27H,7-8,11-12H2,1H3	NCJKIXKEBNQRSY-UHFFFAOYSA-N	795355	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[2-(trifluoromethyl)azetidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 50	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795355	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795355&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253993	528826818							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763108	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC3C(F)(F)F)C4)ccc21	InChI=1S/C22H20F3N5O2/c1-28-17-6-5-15(9-14(17)10-26-28)27-16-4-2-3-13-11-29(21(32)20(13)16)12-19(31)30-8-7-18(30)22(23,24)25/h2-6,9-10,18,27H,7-8,11-12H2,1H3	NCJKIXKEBNQRSY-UHFFFAOYSA-N	795355	7-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[2-(trifluoromethyl)azetidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 50	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795355	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795355&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253993	528826818							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763109	Cn5ncc4cc(Nc3cccc2CN(CC(=O)N1CCC[C@H]1C(F)(F)F)C(=O)c23)cnc45	InChI=1S/C22H21F3N6O2/c1-29-20-14(9-27-29)8-15(10-26-20)28-16-5-2-4-13-11-30(21(33)19(13)16)12-18(32)31-7-3-6-17(31)22(23,24)25/h2,4-5,8-10,17,28H,3,6-7,11-12H2,1H3	HNBRSCXCNBWMSB-UHFFFAOYSA-N	795356	7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 51	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795356	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795356&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254201	528826819							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763110	Cn5ncc4cc(Nc3cccc2CN(CC(=O)N1CCC[C@H]1C(F)(F)F)C(=O)c23)cnc45	InChI=1S/C22H21F3N6O2/c1-29-20-14(9-27-29)8-15(10-26-20)28-16-5-2-4-13-11-30(21(33)19(13)16)12-18(32)31-7-3-6-17(31)22(23,24)25/h2,4-5,8-10,17,28H,3,6-7,11-12H2,1H3	HNBRSCXCNBWMSB-UHFFFAOYSA-N	795356	7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 51	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795356	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795356&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254201	528826819							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763111	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NC3CC3(F)F)C4)cnc21	InChI=1S/C20H18F2N6O2/c1-27-18-12(7-24-27)5-13(8-23-18)25-14-4-2-3-11-9-28(19(30)17(11)14)10-16(29)26-15-6-20(15,21)22/h2-5,7-8,15,25H,6,9-10H2,1H3,(H,26,29)	QSZPRJIUBNGTKN-UHFFFAOYSA-N	795357	N-(2,2-difluorocyclopropyl)-2-[7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 52	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795357	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795357&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253928	528826820							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763112	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NC3CC3(F)F)C4)cnc21	InChI=1S/C20H18F2N6O2/c1-27-18-12(7-24-27)5-13(8-23-18)25-14-4-2-3-11-9-28(19(30)17(11)14)10-16(29)26-15-6-20(15,21)22/h2-5,7-8,15,25H,6,9-10H2,1H3,(H,26,29)	QSZPRJIUBNGTKN-UHFFFAOYSA-N	795357	N-(2,2-difluorocyclopropyl)-2-[7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]acetamide::US20260069571, Example 52	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795357	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795357&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253928	528826820							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763113	C[C@H](NC(=O)CN1Cc2cccc(Nc3cnc4c(cnn4C)c3)c2C1=O)C(F)(F)F	InChI=1S/C20H19F3N6O2/c1-11(20(21,22)23)26-16(30)10-29-9-12-4-3-5-15(17(12)19(29)31)27-14-6-13-7-25-28(2)18(13)24-8-14/h3-8,11,27H,9-10H2,1-2H3,(H,26,30)	HJRYBISOMXSJAA-UHFFFAOYSA-N	795358	2-[7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 53	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795358	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795358&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254231	528826821							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763114	C[C@H](NC(=O)CN1Cc2cccc(Nc3cnc4c(cnn4C)c3)c2C1=O)C(F)(F)F	InChI=1S/C20H19F3N6O2/c1-11(20(21,22)23)26-16(30)10-29-9-12-4-3-5-15(17(12)19(29)31)27-14-6-13-7-25-28(2)18(13)24-8-14/h3-8,11,27H,9-10H2,1-2H3,(H,26,30)	HJRYBISOMXSJAA-UHFFFAOYSA-N	795358	2-[7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 53	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795358	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795358&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254231	528826821							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763115	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCO[C@H](C(F)(F)F)C3)C4)cnc21	InChI=1S/C22H21F3N6O3/c1-29-20-14(8-27-29)7-15(9-26-20)28-16-4-2-3-13-10-31(21(33)19(13)16)12-18(32)30-5-6-34-17(11-30)22(23,24)25/h2-4,7-9,17,28H,5-6,10-12H2,1H3	QZGCJOZWUAFNDY-UHFFFAOYSA-N	795359	7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 54	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795359	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795359&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254026	528826822							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763116	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCO[C@H](C(F)(F)F)C3)C4)cnc21	InChI=1S/C22H21F3N6O3/c1-29-20-14(8-27-29)7-15(9-26-20)28-16-4-2-3-13-10-31(21(33)19(13)16)12-18(32)30-5-6-34-17(11-30)22(23,24)25/h2-4,7-9,17,28H,5-6,10-12H2,1H3	QZGCJOZWUAFNDY-UHFFFAOYSA-N	795359	7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 54	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795359	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795359&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254026	528826822							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763117	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCO[C@@H](C(F)(F)F)C3)C4)cnc21	InChI=1S/C22H21F3N6O3/c1-29-20-14(8-27-29)7-15(9-26-20)28-16-4-2-3-13-10-31(21(33)19(13)16)12-18(32)30-5-6-34-17(11-30)22(23,24)25/h2-4,7-9,17,28H,5-6,10-12H2,1H3	QZGCJOZWUAFNDY-UHFFFAOYSA-N	795360	7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2R)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 55	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795360	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795360&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254110	528826823							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763118	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCO[C@@H](C(F)(F)F)C3)C4)cnc21	InChI=1S/C22H21F3N6O3/c1-29-20-14(8-27-29)7-15(9-26-20)28-16-4-2-3-13-10-31(21(33)19(13)16)12-18(32)30-5-6-34-17(11-30)22(23,24)25/h2-4,7-9,17,28H,5-6,10-12H2,1H3	QZGCJOZWUAFNDY-UHFFFAOYSA-N	795360	7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2R)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 55	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795360	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795360&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254110	528826823							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763119	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC[C@H]3CF)C4)cnc21	InChI=1S/C22H23FN6O2/c1-27-21-15(10-25-27)8-16(11-24-21)26-18-6-2-4-14-12-28(22(31)20(14)18)13-19(30)29-7-3-5-17(29)9-23/h2,4,6,8,10-11,17,26H,3,5,7,9,12-13H2,1H3	APLYAISEQQAGIJ-UHFFFAOYSA-N	795361	7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2S)-(fluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 56	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795361	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795361&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254179	528826824							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
763120	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC[C@H]3CF)C4)cnc21	InChI=1S/C22H23FN6O2/c1-27-21-15(10-25-27)8-16(11-24-21)26-18-6-2-4-14-12-28(22(31)20(14)18)13-19(30)29-7-3-5-17(29)9-23/h2,4,6,8,10-11,17,26H,3,5,7,9,12-13H2,1H3	APLYAISEQQAGIJ-UHFFFAOYSA-N	795361	7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2S)-(fluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 56	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795361	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795361&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254179	528826824							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
763121	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOCC3C(F)(F)F)C4)cnc21	InChI=1S/C22H21F3N6O3/c1-29-20-14(8-27-29)7-15(9-26-20)28-16-4-2-3-13-10-30(21(33)19(13)16)11-18(32)31-5-6-34-12-17(31)22(23,24)25/h2-4,7-9,17,28H,5-6,10-12H2,1H3	OOYCXHUUHZDFQS-UHFFFAOYSA-N	795362	7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(3R)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 57	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2GQ73QH		aid1798497	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795362	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795362&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169814601	528826825							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888782	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOCC3C(F)(F)F)C4)cnc21	InChI=1S/C22H21F3N6O3/c1-29-20-14(8-27-29)7-15(9-26-20)28-16-4-2-3-13-10-30(21(33)19(13)16)11-18(32)31-5-6-34-12-17(31)22(23,24)25/h2-4,7-9,17,28H,5-6,10-12H2,1H3	OOYCXHUUHZDFQS-UHFFFAOYSA-N	795362	7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(3R)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 57	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795362	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795362&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169814601	528826825							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888783	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC[C@H]3C(F)F)C4)cnc21	InChI=1S/C22H22F2N6O2/c1-28-21-14(9-26-28)8-15(10-25-21)27-16-5-2-4-13-11-29(22(32)19(13)16)12-18(31)30-7-3-6-17(30)20(23)24/h2,4-5,8-10,17,20,27H,3,6-7,11-12H2,1H3	GQDURPYVQFXZIY-UHFFFAOYSA-N	795363	7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2S)-(difluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 58	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795363	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795363&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254009	528826826							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888784	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC[C@H]3C(F)F)C4)cnc21	InChI=1S/C22H22F2N6O2/c1-28-21-14(9-26-28)8-15(10-25-21)27-16-5-2-4-13-11-29(22(32)19(13)16)12-18(31)30-7-3-6-17(30)20(23)24/h2,4-5,8-10,17,20,27H,3,6-7,11-12H2,1H3	GQDURPYVQFXZIY-UHFFFAOYSA-N	795363	7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2S)-(difluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 58	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795363	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795363&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254009	528826826							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888785	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cccc(C(F)(F)F)c3)C4)cnc21	InChI=1S/C24H19F3N6O2/c1-32-22-15(10-29-32)8-18(11-28-22)30-19-7-2-4-14-12-33(23(35)21(14)19)13-20(34)31-17-6-3-5-16(9-17)24(25,26)27/h2-11,30H,12-13H2,1H3,(H,31,34)	CQWMCRCNCYONAS-UHFFFAOYSA-N	795364	2-[7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-[3-(trifluoromethyl)phenyl]acetamide::US20260069571, Example 59	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795364	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795364&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254149	528826827							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888786	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cccc(C(F)(F)F)c3)C4)cnc21	InChI=1S/C24H19F3N6O2/c1-32-22-15(10-29-32)8-18(11-28-22)30-19-7-2-4-14-12-33(23(35)21(14)19)13-20(34)31-17-6-3-5-16(9-17)24(25,26)27/h2-11,30H,12-13H2,1H3,(H,31,34)	CQWMCRCNCYONAS-UHFFFAOYSA-N	795364	2-[7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-[3-(trifluoromethyl)phenyl]acetamide::US20260069571, Example 59	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795364	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795364&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254149	528826827							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888787	N#Cc1cc(Nc2cccc3c2C(=O)N(CC(=O)NCC(F)(F)F)C3)cc2cn[nH]c12	InChI=1S/C20H15F3N6O2/c21-20(22,23)10-25-16(30)9-29-8-11-2-1-3-15(17(11)19(29)31)27-14-4-12(6-24)18-13(5-14)7-26-28-18/h1-5,7,27H,8-10H2,(H,25,30)(H,26,28)	BAPNBECTJIXSPJ-UHFFFAOYSA-N	795365	2-[7-[(7-cyano-1H-indazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 60	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795365	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795365&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254067	528826828							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888788	N#Cc1cc(Nc2cccc3c2C(=O)N(CC(=O)NCC(F)(F)F)C3)cc2cn[nH]c12	InChI=1S/C20H15F3N6O2/c21-20(22,23)10-25-16(30)9-29-8-11-2-1-3-15(17(11)19(29)31)27-14-4-12(6-24)18-13(5-14)7-26-28-18/h1-5,7,27H,8-10H2,(H,25,30)(H,26,28)	BAPNBECTJIXSPJ-UHFFFAOYSA-N	795365	2-[7-[(7-cyano-1H-indazol-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 60	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795365	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795365&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254067	528826828							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888789	Cc1n[nH]c2nc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)ccc12	InChI=1S/C19H17F3N6O2/c1-10-12-5-6-14(25-17(12)27-26-10)24-13-4-2-3-11-7-28(18(30)16(11)13)8-15(29)23-9-19(20,21)22/h2-6H,7-9H2,1H3,(H,23,29)(H2,24,25,26,27)	YFFZXHJKAJNJHQ-UHFFFAOYSA-N	795366	2-[7-[(3-methyl-1H-pyrazolo[3,4-b]pyridin-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 61	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795366	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795366&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253998	528826829							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888790	Cc1n[nH]c2nc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)ccc12	InChI=1S/C19H17F3N6O2/c1-10-12-5-6-14(25-17(12)27-26-10)24-13-4-2-3-11-7-28(18(30)16(11)13)8-15(29)23-9-19(20,21)22/h2-6H,7-9H2,1H3,(H,23,29)(H2,24,25,26,27)	YFFZXHJKAJNJHQ-UHFFFAOYSA-N	795366	2-[7-[(3-methyl-1H-pyrazolo[3,4-b]pyridin-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 61	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795366	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795366&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253998	528826829							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888791	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)cc(F)c12	InChI=1S/C20H17F4N5O2/c1-10-17-13(21)5-12(6-15(17)28-27-10)26-14-4-2-3-11-7-29(19(31)18(11)14)8-16(30)25-9-20(22,23)24/h2-6,26H,7-9H2,1H3,(H,25,30)(H,27,28)	ZNABHYCHIRQSMQ-UHFFFAOYSA-N	795367	2-[7-[(4-fluoro-3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 62	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795367	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795367&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254097	528826830							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888792	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)cc(F)c12	InChI=1S/C20H17F4N5O2/c1-10-17-13(21)5-12(6-15(17)28-27-10)26-14-4-2-3-11-7-29(19(31)18(11)14)8-16(30)25-9-20(22,23)24/h2-6,26H,7-9H2,1H3,(H,25,30)(H,27,28)	ZNABHYCHIRQSMQ-UHFFFAOYSA-N	795367	2-[7-[(4-fluoro-3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 62	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795367	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795367&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254097	528826830							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888793	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N[C@@H](C)C(F)(F)F)C4)cc(F)c12	InChI=1S/C21H19F4N5O2/c1-10-18-14(22)6-13(7-16(18)29-28-10)27-15-5-3-4-12-8-30(20(32)19(12)15)9-17(31)26-11(2)21(23,24)25/h3-7,11,27H,8-9H2,1-2H3,(H,26,31)(H,28,29)	GBJACNWVPRFEPG-UHFFFAOYSA-N	795368	2-[7-[(4-fluoro-3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 63	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795368	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795368&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254234	528826831							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888794	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N[C@@H](C)C(F)(F)F)C4)cc(F)c12	InChI=1S/C21H19F4N5O2/c1-10-18-14(22)6-13(7-16(18)29-28-10)27-15-5-3-4-12-8-30(20(32)19(12)15)9-17(31)26-11(2)21(23,24)25/h3-7,11,27H,8-9H2,1-2H3,(H,26,31)(H,28,29)	GBJACNWVPRFEPG-UHFFFAOYSA-N	795368	2-[7-[(4-fluoro-3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 63	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795368	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795368&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254234	528826831							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888795	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC3C(F)(F)F)C4)cc(F)c12	InChI=1S/C23H21F4N5O2/c1-12-20-15(24)8-14(9-17(20)30-29-12)28-16-5-2-4-13-10-31(22(34)21(13)16)11-19(33)32-7-3-6-18(32)23(25,26)27/h2,4-5,8-9,18,28H,3,6-7,10-11H2,1H3,(H,29,30)	PCFHYMUGCZOPLR-UHFFFAOYSA-N	795369	7-[(4-fluoro-3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 64	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795369	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795369&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169816117	528826832							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888796	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC3C(F)(F)F)C4)cc(F)c12	InChI=1S/C23H21F4N5O2/c1-12-20-15(24)8-14(9-17(20)30-29-12)28-16-5-2-4-13-10-31(22(34)21(13)16)11-19(33)32-7-3-6-18(32)23(25,26)27/h2,4-5,8-9,18,28H,3,6-7,10-11H2,1H3,(H,29,30)	PCFHYMUGCZOPLR-UHFFFAOYSA-N	795369	7-[(4-fluoro-3-methyl-1H-indazol-6-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 64	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795369	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795369&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169816117	528826832							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888797	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cnoc3)C4)cc(F)c12	InChI=1S/C21H17FN6O3/c1-11-19-15(22)5-13(6-17(19)27-26-11)24-16-4-2-3-12-8-28(21(30)20(12)16)9-18(29)25-14-7-23-31-10-14/h2-7,10,24H,8-9H2,1H3,(H,25,29)(H,26,27)	QNHUCWSUJIJNAB-UHFFFAOYSA-N	795370	2-[7-[(4-fluoro-3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-isoxazol-4-yl-acetamide::US20260069571, Example 65	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795370	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795370&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254219	528826833							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888798	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cnoc3)C4)cc(F)c12	InChI=1S/C21H17FN6O3/c1-11-19-15(22)5-13(6-17(19)27-26-11)24-16-4-2-3-12-8-28(21(30)20(12)16)9-18(29)25-14-7-23-31-10-14/h2-7,10,24H,8-9H2,1H3,(H,25,29)(H,26,27)	QNHUCWSUJIJNAB-UHFFFAOYSA-N	795370	2-[7-[(4-fluoro-3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-isoxazol-4-yl-acetamide::US20260069571, Example 65	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795370	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795370&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254219	528826833							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888799	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N[C@@H](C)C(F)(F)F)C4)cnc12	InChI=1S/C20H19F3N6O2/c1-10-18-15(28-27-10)6-13(7-24-18)26-14-5-3-4-12-8-29(19(31)17(12)14)9-16(30)25-11(2)20(21,22)23/h3-7,11,26H,8-9H2,1-2H3,(H,25,30)(H,27,28)	NECPLICHUCENEZ-UHFFFAOYSA-N	795371	2-[7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 66	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795371	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795371&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253945	528826834							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888800	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N[C@@H](C)C(F)(F)F)C4)cnc12	InChI=1S/C20H19F3N6O2/c1-10-18-15(28-27-10)6-13(7-24-18)26-14-5-3-4-12-8-29(19(31)17(12)14)9-16(30)25-11(2)20(21,22)23/h3-7,11,26H,8-9H2,1-2H3,(H,25,30)(H,27,28)	NECPLICHUCENEZ-UHFFFAOYSA-N	795371	2-[7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 66	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795371	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795371&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253945	528826834							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888801	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC3C(F)(F)F)C4)cnc12	InChI=1S/C22H21F3N6O2/c1-12-20-16(29-28-12)8-14(9-26-20)27-15-5-2-4-13-10-30(21(33)19(13)15)11-18(32)31-7-3-6-17(31)22(23,24)25/h2,4-5,8-9,17,27H,3,6-7,10-11H2,1H3,(H,28,29)	KIMKTBVTICUOPF-UHFFFAOYSA-N	795372	7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 67	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795372	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795372&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253987	528826835							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888802	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC3C(F)(F)F)C4)cnc12	InChI=1S/C22H21F3N6O2/c1-12-20-16(29-28-12)8-14(9-26-20)27-15-5-2-4-13-10-30(21(33)19(13)15)11-18(32)31-7-3-6-17(31)22(23,24)25/h2,4-5,8-9,17,27H,3,6-7,10-11H2,1H3,(H,28,29)	KIMKTBVTICUOPF-UHFFFAOYSA-N	795372	7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 67	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795372	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795372&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253987	528826835							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888803	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCO[C@@H](C(F)(F)F)C3)C4)cnc12	InChI=1S/C22H21F3N6O3/c1-12-20-16(29-28-12)7-14(8-26-20)27-15-4-2-3-13-9-31(21(33)19(13)15)11-18(32)30-5-6-34-17(10-30)22(23,24)25/h2-4,7-8,17,27H,5-6,9-11H2,1H3,(H,28,29)	ZCXMMFDDVXCTAW-UHFFFAOYSA-N	795373	7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-2-[2-oxo-2-[(2R)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 68	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795373	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795373&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169816182	528826836							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888804	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCO[C@@H](C(F)(F)F)C3)C4)cnc12	InChI=1S/C22H21F3N6O3/c1-12-20-16(29-28-12)7-14(8-26-20)27-15-4-2-3-13-9-31(21(33)19(13)15)11-18(32)30-5-6-34-17(10-30)22(23,24)25/h2-4,7-8,17,27H,5-6,9-11H2,1H3,(H,28,29)	ZCXMMFDDVXCTAW-UHFFFAOYSA-N	795373	7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-2-[2-oxo-2-[(2R)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 68	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795373	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795373&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169816182	528826836							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888805	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCO[C@H](C(F)(F)F)C3)C4)cnc12	InChI=1S/C22H21F3N6O3/c1-12-20-16(29-28-12)7-14(8-26-20)27-15-4-2-3-13-9-31(21(33)19(13)15)11-18(32)30-5-6-34-17(10-30)22(23,24)25/h2-4,7-8,17,27H,5-6,9-11H2,1H3,(H,28,29)	ZCXMMFDDVXCTAW-UHFFFAOYSA-N	795374	7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 69	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804320	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795374	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795374&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169816241	528826837							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888806	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCO[C@H](C(F)(F)F)C3)C4)cnc12	InChI=1S/C22H21F3N6O3/c1-12-20-16(29-28-12)7-14(8-26-20)27-15-4-2-3-13-9-31(21(33)19(13)15)11-18(32)30-5-6-34-17(10-30)22(23,24)25/h2-4,7-8,17,27H,5-6,9-11H2,1H3,(H,28,29)	ZCXMMFDDVXCTAW-UHFFFAOYSA-N	795374	7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 69	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795374	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795374&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169816241	528826837							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888807	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOCC3C(F)(F)F)C4)cnc12	InChI=1S/C22H21F3N6O3/c1-12-20-16(29-28-12)7-14(8-26-20)27-15-4-2-3-13-9-30(21(33)19(13)15)10-18(32)31-5-6-34-11-17(31)22(23,24)25/h2-4,7-8,17,27H,5-6,9-11H2,1H3,(H,28,29)	UHQZKKQVMCHJOM-UHFFFAOYSA-N	795375	7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-2-[2-oxo-2-[(3S)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 70	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804320	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795375	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795375&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254093	528826838							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888808	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOCC3C(F)(F)F)C4)cnc12	InChI=1S/C22H21F3N6O3/c1-12-20-16(29-28-12)7-14(8-26-20)27-15-4-2-3-13-9-30(21(33)19(13)15)10-18(32)31-5-6-34-11-17(31)22(23,24)25/h2-4,7-8,17,27H,5-6,9-11H2,1H3,(H,28,29)	UHQZKKQVMCHJOM-UHFFFAOYSA-N	795375	7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-2-[2-oxo-2-[(3S)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 70	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2GQ73QH		aid1804320	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795375	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795375&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254093	528826838							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888809	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOCC3C(F)(F)F)C4)cnc12	InChI=1S/C22H21F3N6O3/c1-12-20-16(29-28-12)7-14(8-26-20)27-15-4-2-3-13-9-30(21(33)19(13)15)10-18(32)31-5-6-34-11-17(31)22(23,24)25/h2-4,7-8,17,27H,5-6,9-11H2,1H3,(H,28,29)	UHQZKKQVMCHJOM-UHFFFAOYSA-N	795376	7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-2-[2-oxo-2-[(3R)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 71	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804320	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795376	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795376&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169816288	528826839							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888810	Cc1n[nH]c2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCOCC3C(F)(F)F)C4)cnc12	InChI=1S/C22H21F3N6O3/c1-12-20-16(29-28-12)7-14(8-26-20)27-15-4-2-3-13-9-30(21(33)19(13)15)10-18(32)31-5-6-34-11-17(31)22(23,24)25/h2-4,7-8,17,27H,5-6,9-11H2,1H3,(H,28,29)	UHQZKKQVMCHJOM-UHFFFAOYSA-N	795376	7-[(3-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)amino]-2-[2-oxo-2-[(3R)-(trifluoromethyl)morpholin-4-yl]ethyl]isoindolin-1-one::US20260069571, Example 71	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804320	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795376	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795376&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169816288	528826839							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888811	C[C@H](NC(=O)CN1Cc2cccc(NC3C=c4cn[nH]c4=NC3)c2C1=O)C(F)(F)F	InChI=1S/C19H19F3N6O2/c1-10(19(20,21)22)25-15(29)9-28-8-11-3-2-4-14(16(11)18(28)30)26-13-5-12-6-24-27-17(12)23-7-13/h2-6,10,13,26H,7-9H2,1H3,(H,23,27)(H,25,29)	CNCWOJALZKGXRD-UHFFFAOYSA-N	795377	2-[1-oxo-7-(1H-pyrazolo[3,4-b]pyridin-5-ylamino)isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 73	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804320	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795377	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795377&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			178423182	528826840							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888812	C[C@H](NC(=O)CN1Cc2cccc(NC3C=c4cn[nH]c4=NC3)c2C1=O)C(F)(F)F	InChI=1S/C19H19F3N6O2/c1-10(19(20,21)22)25-15(29)9-28-8-11-3-2-4-14(16(11)18(28)30)26-13-5-12-6-24-27-17(12)23-7-13/h2-6,10,13,26H,7-9H2,1H3,(H,23,27)(H,25,29)	CNCWOJALZKGXRD-UHFFFAOYSA-N	795377	2-[1-oxo-7-(1H-pyrazolo[3,4-b]pyridin-5-ylamino)isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 73	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804320	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795377	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795377&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			178423182	528826840							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888813	O=C1c2c(cccc2Nc2cnc3[nH]ncc3c2)CN1CC(=O)N1CCCC1C(F)(F)F	InChI=1S/C21H19F3N6O2/c22-21(23,24)16-5-2-6-30(16)17(31)11-29-10-12-3-1-4-15(18(12)20(29)32)27-14-7-13-8-26-28-19(13)25-9-14/h1,3-4,7-9,16,27H,2,5-6,10-11H2,(H,25,26,28)	VFATXIUQIPZJNM-UHFFFAOYSA-N	795378	2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]-7-(1H-pyrazolo[3,4-b]pyridin-5-ylamino)isoindolin-1-one::US20260069571, Example 74	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804320	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795378	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795378&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253948	528826841							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888814	O=C1c2c(cccc2Nc2cnc3[nH]ncc3c2)CN1CC(=O)N1CCCC1C(F)(F)F	InChI=1S/C21H19F3N6O2/c22-21(23,24)16-5-2-6-30(16)17(31)11-29-10-12-3-1-4-15(18(12)20(29)32)27-14-7-13-8-26-28-19(13)25-9-14/h1,3-4,7-9,16,27H,2,5-6,10-11H2,(H,25,26,28)	VFATXIUQIPZJNM-UHFFFAOYSA-N	795378	2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]-7-(1H-pyrazolo[3,4-b]pyridin-5-ylamino)isoindolin-1-one::US20260069571, Example 74	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804320	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795378	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795378&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253948	528826841							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888815	O=C(CN1Cc2cccc(Nc3cnc4[nH]ncc4c3)c2C1=O)NC1CC1(F)F	InChI=1S/C19H16F2N6O2/c20-19(21)5-14(19)25-15(28)9-27-8-10-2-1-3-13(16(10)18(27)29)24-12-4-11-6-23-26-17(11)22-7-12/h1-4,6-7,14,24H,5,8-9H2,(H,25,28)(H,22,23,26)	FUZCGNMAPRZUHL-UHFFFAOYSA-N	795379	N-(2,2-difluorocyclopropyl)-2-[1-oxo-7-(1H-pyrazolo[3,4-b]pyridin-5-ylamino)isoindolin-2-yl]acetamide::US20260069571, Example 75	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795379	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795379&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253981	528826842							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888816	O=C(CN1Cc2cccc(Nc3cnc4[nH]ncc4c3)c2C1=O)NC1CC1(F)F	InChI=1S/C19H16F2N6O2/c20-19(21)5-14(19)25-15(28)9-27-8-10-2-1-3-13(16(10)18(27)29)24-12-4-11-6-23-26-17(11)22-7-12/h1-4,6-7,14,24H,5,8-9H2,(H,25,28)(H,22,23,26)	FUZCGNMAPRZUHL-UHFFFAOYSA-N	795379	N-(2,2-difluorocyclopropyl)-2-[1-oxo-7-(1H-pyrazolo[3,4-b]pyridin-5-ylamino)isoindolin-2-yl]acetamide::US20260069571, Example 75	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795379	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795379&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253981	528826842							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888817	CN(CC(F)(F)F)C(=O)CN1Cc2cccc(Nc3cnc4[nH]ncc4c3)c2C1=O	InChI=1S/C19H17F3N6O2/c1-27(10-19(20,21)22)15(29)9-28-8-11-3-2-4-14(16(11)18(28)30)25-13-5-12-6-24-26-17(12)23-7-13/h2-7,25H,8-10H2,1H3,(H,23,24,26)	ITROMUQYMPTACW-UHFFFAOYSA-N	795380	N-methyl-2-[1-oxo-7-(1H-pyrazolo[3,4-b]pyridin-5-ylamino)isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 76	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795380	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795380&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254202	528826843							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888818	CN(CC(F)(F)F)C(=O)CN1Cc2cccc(Nc3cnc4[nH]ncc4c3)c2C1=O	InChI=1S/C19H17F3N6O2/c1-27(10-19(20,21)22)15(29)9-28-8-11-3-2-4-14(16(11)18(28)30)25-13-5-12-6-24-26-17(12)23-7-13/h2-7,25H,8-10H2,1H3,(H,23,24,26)	ITROMUQYMPTACW-UHFFFAOYSA-N	795380	N-methyl-2-[1-oxo-7-(1H-pyrazolo[3,4-b]pyridin-5-ylamino)isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 76	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795380	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795380&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254202	528826843							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888819	CC(N(C)C(=O)CN1Cc2cccc(Nc3cnc4[nH]ncc4c3)c2C1=O)C(F)(F)F	InChI=1S/C20H19F3N6O2/c1-11(20(21,22)23)28(2)16(30)10-29-9-12-4-3-5-15(17(12)19(29)31)26-14-6-13-7-25-27-18(13)24-8-14/h3-8,11,26H,9-10H2,1-2H3,(H,24,25,27)	QBAKJDQNEWRDFI-UHFFFAOYSA-N	795381	N-methyl-2-[1-oxo-7-(1H-pyrazolo[3,4-b]pyridin-5-ylamino)isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 77	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795381	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795381&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254079	528826844							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888820	CC(N(C)C(=O)CN1Cc2cccc(Nc3cnc4[nH]ncc4c3)c2C1=O)C(F)(F)F	InChI=1S/C20H19F3N6O2/c1-11(20(21,22)23)28(2)16(30)10-29-9-12-4-3-5-15(17(12)19(29)31)26-14-6-13-7-25-27-18(13)24-8-14/h3-8,11,26H,9-10H2,1-2H3,(H,24,25,27)	QBAKJDQNEWRDFI-UHFFFAOYSA-N	795381	N-methyl-2-[1-oxo-7-(1H-pyrazolo[3,4-b]pyridin-5-ylamino)isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 77	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795381	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795381&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254079	528826844							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888821	Cc3n[nH]c4cc(N(C)c2cccc1CN(CC(=O)NCC(F)(F)F)C(=O)c12)ccc34	InChI=1S/C21H20F3N5O2/c1-12-15-7-6-14(8-16(15)27-26-12)28(2)17-5-3-4-13-9-29(20(31)19(13)17)10-18(30)25-11-21(22,23)24/h3-8H,9-11H2,1-2H3,(H,25,30)(H,26,27)	KBJDMZHMOUHJOU-UHFFFAOYSA-N	795382	US20260069571, Example 78	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795382	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795382&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253925	528826845							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888822	Cc3n[nH]c4cc(N(C)c2cccc1CN(CC(=O)NCC(F)(F)F)C(=O)c12)ccc34	InChI=1S/C21H20F3N5O2/c1-12-15-7-6-14(8-16(15)27-26-12)28(2)17-5-3-4-13-9-29(20(31)19(13)17)10-18(30)25-11-21(22,23)24/h3-8H,9-11H2,1-2H3,(H,25,30)(H,26,27)	KBJDMZHMOUHJOU-UHFFFAOYSA-N	795382	US20260069571, Example 78	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795382	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795382&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253925	528826845							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888823	Cn4ncc3cc(Nc1cccc2c1C(=O)N(CC(=O)NCC(F)(F)F)C2(F)F)ccc34	InChI=1S/C20H16F5N5O2/c1-29-15-6-5-12(7-11(15)8-27-29)28-14-4-2-3-13-17(14)18(32)30(20(13,24)25)9-16(31)26-10-19(21,22)23/h2-8,28H,9-10H2,1H3,(H,26,31)	ISBPDNWHFBWVEM-UHFFFAOYSA-N	795383	US20260069571, Example 79	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795383	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795383&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254016	528826846							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888824	Cn4ncc3cc(Nc1cccc2c1C(=O)N(CC(=O)NCC(F)(F)F)C2(F)F)ccc34	InChI=1S/C20H16F5N5O2/c1-29-15-6-5-12(7-11(15)8-27-29)28-14-4-2-3-13-17(14)18(32)30(20(13,24)25)9-16(31)26-10-19(21,22)23/h2-8,28H,9-10H2,1H3,(H,26,31)	ISBPDNWHFBWVEM-UHFFFAOYSA-N	795383	US20260069571, Example 79	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795383	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795383&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254016	528826846							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888825	CC(C)c1n[nH]c2cc(NC3C=CC=C4CN(CC(=O)NCC(F)(F)F)C(=O)C43)ccc12	InChI=1S/C22H24F3N5O2/c1-12(2)20-15-7-6-14(8-17(15)28-29-20)27-16-5-3-4-13-9-30(21(32)19(13)16)10-18(31)26-11-22(23,24)25/h3-8,12,16,19,27H,9-11H2,1-2H3,(H,26,31)(H,28,29)	FNXTZQSGJPJPPU-UHFFFAOYSA-N	795384	2-[7-[(3-isopropyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 80	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795384	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795384&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			178423183	528826847							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888826	CC(C)c1n[nH]c2cc(NC3C=CC=C4CN(CC(=O)NCC(F)(F)F)C(=O)C43)ccc12	InChI=1S/C22H24F3N5O2/c1-12(2)20-15-7-6-14(8-17(15)28-29-20)27-16-5-3-4-13-9-30(21(32)19(13)16)10-18(31)26-11-22(23,24)25/h3-8,12,16,19,27H,9-11H2,1-2H3,(H,26,31)(H,28,29)	FNXTZQSGJPJPPU-UHFFFAOYSA-N	795384	2-[7-[(3-isopropyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 80	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795384	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795384&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			178423183	528826847							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888827	O=C(CN1CC2=CC=CC(Nc3ccc4cn[nH]c4c3)C2C1=O)NCC(F)(F)F	InChI=1S/C19H18F3N5O2/c20-19(21,22)10-23-16(28)9-27-8-12-2-1-3-14(17(12)18(27)29)25-13-5-4-11-7-24-26-15(11)6-13/h1-7,14,17,25H,8-10H2,(H,23,28)(H,24,26)	YMDROPVPLRXKND-UHFFFAOYSA-N	795385	2-[7-(1H-indazol-6-ylamino)-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 81	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795385	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795385&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			178423184	528826848							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888828	O=C(CN1CC2=CC=CC(Nc3ccc4cn[nH]c4c3)C2C1=O)NCC(F)(F)F	InChI=1S/C19H18F3N5O2/c20-19(21,22)10-23-16(28)9-27-8-12-2-1-3-14(17(12)18(27)29)25-13-5-4-11-7-24-26-15(11)6-13/h1-7,14,17,25H,8-10H2,(H,23,28)(H,24,26)	YMDROPVPLRXKND-UHFFFAOYSA-N	795385	2-[7-(1H-indazol-6-ylamino)-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 81	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795385	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795385&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			178423184	528826848							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888829	N#Cc4n[nH]c5ccc(Nc3cccc2CN(CC(=O)N1CCCC1C(F)(F)F)C(=O)c23)cc45	InChI=1S/C23H19F3N6O2/c24-23(25,26)19-5-2-8-32(19)20(33)12-31-11-13-3-1-4-17(21(13)22(31)34)28-14-6-7-16-15(9-14)18(10-27)30-29-16/h1,3-4,6-7,9,19,28H,2,5,8,11-12H2,(H,29,30)	XBUDFXUNORZPLJ-UHFFFAOYSA-N	795386	US20260069571, Example 82	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795386	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795386&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254129	528826849							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888830	N#Cc4n[nH]c5ccc(Nc3cccc2CN(CC(=O)N1CCCC1C(F)(F)F)C(=O)c23)cc45	InChI=1S/C23H19F3N6O2/c24-23(25,26)19-5-2-8-32(19)20(33)12-31-11-13-3-1-4-17(21(13)22(31)34)28-14-6-7-16-15(9-14)18(10-27)30-29-16/h1,3-4,6-7,9,19,28H,2,5,8,11-12H2,(H,29,30)	XBUDFXUNORZPLJ-UHFFFAOYSA-N	795386	US20260069571, Example 82	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795386	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795386&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254129	528826849							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888831	O=C1c2c(cccc2Nc2ccc3[nH]nc(F)c3c2)CN1CC(=O)N1CCCC1C(F)(F)F	InChI=1S/C22H19F4N5O2/c23-20-14-9-13(6-7-15(14)28-29-20)27-16-4-1-3-12-10-30(21(33)19(12)16)11-18(32)31-8-2-5-17(31)22(24,25)26/h1,3-4,6-7,9,17,27H,2,5,8,10-11H2,(H,28,29)	ZNBKZXLHAHATIY-UHFFFAOYSA-N	795387	US20260069571, Example 83	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795387	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795387&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254054	528826850							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888832	O=C1c2c(cccc2Nc2ccc3[nH]nc(F)c3c2)CN1CC(=O)N1CCCC1C(F)(F)F	InChI=1S/C22H19F4N5O2/c23-20-14-9-13(6-7-15(14)28-29-20)27-16-4-1-3-12-10-30(21(33)19(12)16)11-18(32)31-8-2-5-17(31)22(24,25)26/h1,3-4,6-7,9,17,27H,2,5,8,10-11H2,(H,28,29)	ZNBKZXLHAHATIY-UHFFFAOYSA-N	795387	US20260069571, Example 83	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795387	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795387&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254054	528826850							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888833	O=C1c2c(cccc2Nc2ccc3[nH]ncc3n2)CN1CC(=O)N1CCCC1C(F)(F)F	InChI=1S/C21H19F3N6O2/c22-21(23,24)16-5-2-8-30(16)18(31)11-29-10-12-3-1-4-14(19(12)20(29)32)26-17-7-6-13-15(27-17)9-25-28-13/h1,3-4,6-7,9,16H,2,5,8,10-11H2,(H,25,28)(H,26,27)	MZGFGEKPTPVRKG-UHFFFAOYSA-N	795388	US20260069571, Example 84	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795388	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795388&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169784093	528826851							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888834	O=C1c2c(cccc2Nc2ccc3[nH]ncc3n2)CN1CC(=O)N1CCCC1C(F)(F)F	InChI=1S/C21H19F3N6O2/c22-21(23,24)16-5-2-8-30(16)18(31)11-29-10-12-3-1-4-14(19(12)20(29)32)26-17-7-6-13-15(27-17)9-25-28-13/h1,3-4,6-7,9,16H,2,5,8,10-11H2,(H,25,28)(H,26,27)	MZGFGEKPTPVRKG-UHFFFAOYSA-N	795388	US20260069571, Example 84	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795388	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795388&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169784093	528826851							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888835	Cn1ncc2nc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC3C(F)(F)F)C4)ccc21	InChI=1S/C22H21F3N6O2/c1-29-16-7-8-18(28-15(16)10-26-29)27-14-5-2-4-13-11-30(21(33)20(13)14)12-19(32)31-9-3-6-17(31)22(23,24)25/h2,4-5,7-8,10,17H,3,6,9,11-12H2,1H3,(H,27,28)	JONBXIQIWZHWPR-UHFFFAOYSA-N	795389	7-[(1-methylpyrazolo[4,3-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 85	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795389	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795389&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169816289	528826852							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888836	Cn1ncc2nc(Nc3cccc4c3C(=O)N(CC(=O)N3CCCC3C(F)(F)F)C4)ccc21	InChI=1S/C22H21F3N6O2/c1-29-16-7-8-18(28-15(16)10-26-29)27-14-5-2-4-13-11-30(21(33)20(13)14)12-19(32)31-9-3-6-17(31)22(23,24)25/h2,4-5,7-8,10,17H,3,6,9,11-12H2,1H3,(H,27,28)	JONBXIQIWZHWPR-UHFFFAOYSA-N	795389	7-[(1-methylpyrazolo[4,3-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 85	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795389	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795389&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169816289	528826852							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888837	CN(c2ccc1[nH]nc(C#N)c1c2)c5cccc4CN(CC(=O)N3CCC[C@H]3C(F)(F)F)C(=O)c45	InChI=1S/C24H21F3N6O2/c1-31(15-7-8-17-16(10-15)18(11-28)30-29-17)19-5-2-4-14-12-32(23(35)22(14)19)13-21(34)33-9-3-6-20(33)24(25,26)27/h2,4-5,7-8,10,20H,3,6,9,12-13H2,1H3,(H,29,30)	HPVQQUWNCJTRSH-UHFFFAOYSA-N	795390	US20260069571, Example 86	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795390	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795390&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253973	528826853							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888838	CN(c2ccc1[nH]nc(C#N)c1c2)c5cccc4CN(CC(=O)N3CCC[C@H]3C(F)(F)F)C(=O)c45	InChI=1S/C24H21F3N6O2/c1-31(15-7-8-17-16(10-15)18(11-28)30-29-17)19-5-2-4-14-12-32(23(35)22(14)19)13-21(34)33-9-3-6-20(33)24(25,26)27/h2,4-5,7-8,10,20H,3,6,9,12-13H2,1H3,(H,29,30)	HPVQQUWNCJTRSH-UHFFFAOYSA-N	795390	US20260069571, Example 86	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795390	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795390&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253973	528826853							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888839	CN(c1cnc2[nH]ncc2c1)c1cccc2c1C(=O)N(CC(=O)N1CCCC1C(F)(F)F)C2	InChI=1S/C22H21F3N6O2/c1-29(15-8-14-9-27-28-20(14)26-10-15)16-5-2-4-13-11-30(21(33)19(13)16)12-18(32)31-7-3-6-17(31)22(23,24)25/h2,4-5,8-10,17H,3,6-7,11-12H2,1H3,(H,26,27,28)	VJPNWRNTNPJLCR-UHFFFAOYSA-N	795391	7-[methyl(1H-pyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 88	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795391	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795391&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169814598	528826854							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888840	CN(c1cnc2[nH]ncc2c1)c1cccc2c1C(=O)N(CC(=O)N1CCCC1C(F)(F)F)C2	InChI=1S/C22H21F3N6O2/c1-29(15-8-14-9-27-28-20(14)26-10-15)16-5-2-4-13-11-30(21(33)19(13)16)12-18(32)31-7-3-6-17(31)22(23,24)25/h2,4-5,8-10,17H,3,6-7,11-12H2,1H3,(H,26,27,28)	VJPNWRNTNPJLCR-UHFFFAOYSA-N	795391	7-[methyl(1H-pyrazolo[3,4-b]pyridin-5-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 88	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795391	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795391&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169814598	528826854							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888841	C[C@H](NC(=O)CN1Cc2cccc(N(C)c3cnc4[nH]ncc4c3)c2C1=O)C(F)(F)F	InChI=1S/C20H19F3N6O2/c1-11(20(21,22)23)26-16(30)10-29-9-12-4-3-5-15(17(12)19(29)31)28(2)14-6-13-7-25-27-18(13)24-8-14/h3-8,11H,9-10H2,1-2H3,(H,26,30)(H,24,25,27)	MDTPRKWECZBDHA-UHFFFAOYSA-N	795392	2-[7-[methyl(1H-pyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 89	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795392	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795392&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253962	528826855							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888842	C[C@H](NC(=O)CN1Cc2cccc(N(C)c3cnc4[nH]ncc4c3)c2C1=O)C(F)(F)F	InChI=1S/C20H19F3N6O2/c1-11(20(21,22)23)26-16(30)10-29-9-12-4-3-5-15(17(12)19(29)31)28(2)14-6-13-7-25-27-18(13)24-8-14/h3-8,11H,9-10H2,1-2H3,(H,26,30)(H,24,25,27)	MDTPRKWECZBDHA-UHFFFAOYSA-N	795392	2-[7-[methyl(1H-pyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]acetamide::US20260069571, Example 89	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795392	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795392&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253962	528826855							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888843	CN(c1cnc2[nH]ncc2c1)c1cccc2c1C(=O)N(CC(=O)NCC(F)(F)F)C2	InChI=1S/C19H17F3N6O2/c1-27(13-5-12-6-25-26-17(12)23-7-13)14-4-2-3-11-8-28(18(30)16(11)14)9-15(29)24-10-19(20,21)22/h2-7H,8-10H2,1H3,(H,24,29)(H,23,25,26)	DNHFGQOWCSMRQN-UHFFFAOYSA-N	795393	2-[7-[methyl(1H-pyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 90	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795393	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795393&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254163	528826856							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888844	CN(c1cnc2[nH]ncc2c1)c1cccc2c1C(=O)N(CC(=O)NCC(F)(F)F)C2	InChI=1S/C19H17F3N6O2/c1-27(13-5-12-6-25-26-17(12)23-7-13)14-4-2-3-11-8-28(18(30)16(11)14)9-15(29)24-10-19(20,21)22/h2-7H,8-10H2,1H3,(H,24,29)(H,23,25,26)	DNHFGQOWCSMRQN-UHFFFAOYSA-N	795393	2-[7-[methyl(1H-pyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 90	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795393	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795393&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254163	528826856							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888845	Cc1n[nH]c2cc(NC3C=CC=C4CN(CC(=O)NCC(F)(F)F)C(=O)C43)cc(Cl)c12	InChI=1S/C20H19ClF3N5O2/c1-10-17-13(21)5-12(6-15(17)28-27-10)26-14-4-2-3-11-7-29(19(31)18(11)14)8-16(30)25-9-20(22,23)24/h2-6,14,18,26H,7-9H2,1H3,(H,25,30)(H,27,28)	LKTZHNMKZHKBPY-UHFFFAOYSA-N	795394	2-[7-[(4-chloro-3-methyl-1H-indazol-6-yl)amino]-1-oxo-isoindolin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::US20260069571, Example 91	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795394	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795394&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			178423185	528826857							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888846	CN(c1ccc2[nH]nc(F)c2c1)c1cccc2c1C(=O)N(CC(=O)N1CCCC1C(F)(F)F)C2	InChI=1S/C23H21F4N5O2/c1-30(14-7-8-16-15(10-14)21(24)29-28-16)17-5-2-4-13-11-31(22(34)20(13)17)12-19(33)32-9-3-6-18(32)23(25,26)27/h2,4-5,7-8,10,18H,3,6,9,11-12H2,1H3,(H,28,29)	GLQDXCWDQUATNR-UHFFFAOYSA-N	795395	7-[(3-fluoro-1H-indazol-5-yl)-methyl-amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 92	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795395	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795395&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169814600	528826858							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888847	CN(c1ccc2[nH]nc(F)c2c1)c1cccc2c1C(=O)N(CC(=O)N1CCCC1C(F)(F)F)C2	InChI=1S/C23H21F4N5O2/c1-30(14-7-8-16-15(10-14)21(24)29-28-16)17-5-2-4-13-11-31(22(34)20(13)17)12-19(33)32-9-3-6-18(32)23(25,26)27/h2,4-5,7-8,10,18H,3,6,9,11-12H2,1H3,(H,28,29)	GLQDXCWDQUATNR-UHFFFAOYSA-N	795395	7-[(3-fluoro-1H-indazol-5-yl)-methyl-amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 92	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795395	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795395&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169814600	528826858							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888848	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)cc(F)c21	InChI=1S/C20H17F4N5O2/c1-28-18-12(7-26-28)5-13(6-14(18)21)27-15-4-2-3-11-8-29(19(31)17(11)15)9-16(30)25-10-20(22,23)24/h2-7,27H,8-10H2,1H3,(H,25,30)	VGYJPKIJTZHZRR-UHFFFAOYSA-N	795396	US20260069571, Example 93	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795396	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795396&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254001	528826859							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888849	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)cc(F)c21	InChI=1S/C20H17F4N5O2/c1-28-18-12(7-26-28)5-13(6-14(18)21)27-15-4-2-3-11-8-29(19(31)17(11)15)9-16(30)25-10-20(22,23)24/h2-7,27H,8-10H2,1H3,(H,25,30)	VGYJPKIJTZHZRR-UHFFFAOYSA-N	795396	US20260069571, Example 93	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795396	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795396&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254001	528826859							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888850	CN(c1ccc2c(cnn2C)c1)c1cccc2c1C(=O)N(CC(=O)N1CCC[C@H]1C(F)F)C2	InChI=1S/C24H25F2N5O2/c1-28(17-8-9-18-16(11-17)12-27-29(18)2)19-6-3-5-15-13-30(24(33)22(15)19)14-21(32)31-10-4-7-20(31)23(25)26/h3,5-6,8-9,11-12,20,23H,4,7,10,13-14H2,1-2H3	DDJTUVHBYVZEBE-UHFFFAOYSA-N	795397	7-[methyl-(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[(2S)-(difluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 95	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795397	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795397&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			177897596	528826860							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888851	CN(c1ccc2c(cnn2C)c1)c1cccc2c1C(=O)N(CC(=O)N1CCC[C@H]1C(F)F)C2	InChI=1S/C24H25F2N5O2/c1-28(17-8-9-18-16(11-17)12-27-29(18)2)19-6-3-5-15-13-30(24(33)22(15)19)14-21(32)31-10-4-7-20(31)23(25)26/h3,5-6,8-9,11-12,20,23H,4,7,10,13-14H2,1-2H3	DDJTUVHBYVZEBE-UHFFFAOYSA-N	795397	7-[methyl-(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[(2S)-(difluoromethyl)pyrrolidin-1-yl]ethyl]isoindolin-1-one::US20260069571, Example 95	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795397	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795397&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			177897596	528826860							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888852	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC[C@H]3C(F)(F)F)C4)cc(F)c21	InChI=1S/C23H21F4N5O2/c1-30-21-14(10-28-30)8-15(9-16(21)24)29-17-5-2-4-13-11-31(22(34)20(13)17)12-19(33)32-7-3-6-18(32)23(25,26)27/h2,4-5,8-10,18,29H,3,6-7,11-12H2,1H3	LTYQLVADDNNDRG-UHFFFAOYSA-N	795398	US20260069571, Example 96	Epithelial discoidin domain-containing receptor 1	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795398	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795398&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254125	528826861							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888853	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC[C@H]3C(F)(F)F)C4)cc(F)c21	InChI=1S/C23H21F4N5O2/c1-30-21-14(10-28-30)8-15(9-16(21)24)29-17-5-2-4-13-11-31(22(34)20(13)17)12-19(33)32-7-3-6-18(32)23(25,26)27/h2,4-5,8-10,18,29H,3,6-7,11-12H2,1H3	LTYQLVADDNNDRG-UHFFFAOYSA-N	795398	US20260069571, Example 96	Discoidin domain-containing receptor 2	Homo sapiens		<10							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795398	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795398&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254125	528826861							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888854	Cn1ncc2cc(Nc3nccc4c3C(=O)N(CC(=O)N3CCCC3C(F)(F)F)C4)ccc21	InChI=1S/C22H21F3N6O2/c1-29-16-5-4-15(9-14(16)10-27-29)28-20-19-13(6-7-26-20)11-30(21(19)33)12-18(32)31-8-2-3-17(31)22(23,24)25/h4-7,9-10,17H,2-3,8,11-12H2,1H3,(H,26,28)	DASOQOAMARCOPK-UHFFFAOYSA-N	795399	4-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]-1H-pyrrolo[3,4-c]pyridin-3-one::US20260069571, Example 97	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795399	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795399&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			169816349	528826862							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888855	Cn1ncc2cc(Nc3nccc4c3C(=O)N(CC(=O)N3CCCC3C(F)(F)F)C4)ccc21	InChI=1S/C22H21F3N6O2/c1-29-16-5-4-15(9-14(16)10-27-29)28-20-19-13(6-7-26-20)11-30(21(19)33)12-18(32)31-8-2-3-17(31)22(23,24)25/h4-7,9-10,17H,2-3,8,11-12H2,1H3,(H,26,28)	DASOQOAMARCOPK-UHFFFAOYSA-N	795399	4-[(1-methylindazol-5-yl)amino]-2-[2-oxo-2-[(2S)-(trifluoromethyl)pyrrolidin-1-yl]ethyl]-1H-pyrrolo[3,4-c]pyridin-3-one::US20260069571, Example 97	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795399	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795399&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			169816349	528826862							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888856	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cncc(C(F)(F)F)c3)C4)cnc21	InChI=1S/C23H18F3N7O2/c1-32-21-14(7-29-32)5-16(10-28-21)30-18-4-2-3-13-11-33(22(35)20(13)18)12-19(34)31-17-6-15(8-27-9-17)23(24,25)26/h2-10,30H,11-12H2,1H3,(H,31,34)	MIOXMGZQTMSMLT-UHFFFAOYSA-N	795400	2-[7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-[5-(trifluoromethyl)-3-pyridyl]acetamide::US20260069571, Example 99	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795400	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795400&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254213	528826863							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888857	Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cncc(C(F)(F)F)c3)C4)cnc21	InChI=1S/C23H18F3N7O2/c1-32-21-14(7-29-32)5-16(10-28-21)30-18-4-2-3-13-11-33(22(35)20(13)18)12-19(34)31-17-6-15(8-27-9-17)23(24,25)26/h2-10,30H,11-12H2,1H3,(H,31,34)	MIOXMGZQTMSMLT-UHFFFAOYSA-N	795400	2-[7-[(1-methylpyrazolo[3,4-b]pyridin-5-yl)amino]-1-oxo-isoindolin-2-yl]-N-[5-(trifluoromethyl)-3-pyridyl]acetamide::US20260069571, Example 99	Discoidin domain-containing receptor 2	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795400	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795400&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254213	528826863							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888858	Cc1nn(C)c2ncc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)cc12	InChI=1S/C20H19F3N6O2/c1-11-14-6-13(7-24-18(14)28(2)27-11)26-15-5-3-4-12-8-29(19(31)17(12)15)9-16(30)25-10-20(21,22)23/h3-7,26H,8-10H2,1-2H3,(H,25,30)	VVYBYPUNJJJLHQ-UHFFFAOYSA-N	795401	US20260069571, Example 101	Epithelial discoidin domain-containing receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795401	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795401&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168253950	528826864							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888859	Cc1nn(C)c2ncc(Nc3cccc4c3C(=O)N(CC(=O)NCC(F)(F)F)C4)cc12	InChI=1S/C20H19F3N6O2/c1-11-14-6-13(7-24-18(14)28(2)27-11)26-15-5-3-4-12-8-29(19(31)17(12)15)9-16(30)25-10-20(21,22)23/h3-7,26H,8-10H2,1-2H3,(H,25,30)	VVYBYPUNJJJLHQ-UHFFFAOYSA-N	795401	US20260069571, Example 101	Discoidin domain-containing receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795401	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795401&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168253950	528826864							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
888860	Cc1nn(C)c2ncc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC[C@H]3C(F)(F)F)C4)cc12	InChI=1S/C23H23F3N6O2/c1-13-16-9-15(10-27-21(16)30(2)29-13)28-17-6-3-5-14-11-31(22(34)20(14)17)12-19(33)32-8-4-7-18(32)23(24,25)26/h3,5-6,9-10,18,28H,4,7-8,11-12H2,1-2H3	VXHZJLJJLRHGBN-UHFFFAOYSA-N	795402	US20260069571, Example 102	Epithelial discoidin domain-containing receptor 1	Homo sapiens		 55							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795402	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3993&target=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795402&enzyme=Epithelial+discoidin+domain-containing+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			168254012	528826865							1	MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV	6BSD,6BRJ,5BVW,5BVO,5BVN,5BVK,5FDX,5FDP,7BE6,7BCM,6HP9,6GWR,4CKR,4BKJ,3ZOS,6FIQ,6FIO,6FIN,6FIL,6FEX,6FEW,5SB2,5SB1,5SB0,5SAZ,5SAY,5SAX,5SAW,5SAV,5SAU,7FEH,8PE9	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN	Q08345	B5A975 B5A976 B7Z2K0 Q14196 Q16562 Q2L6H3 Q4LE50 Q5ST11 Q5ST12 Q6NSK4 Q9UD35 Q9UD36 Q9UD37 Q9UD86 Q9UDL2			N/A	A0A024RCL1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
888861	Cc1nn(C)c2ncc(Nc3cccc4c3C(=O)N(CC(=O)N3CCC[C@H]3C(F)(F)F)C4)cc12	InChI=1S/C23H23F3N6O2/c1-13-16-9-15(10-27-21(16)30(2)29-13)28-17-6-3-5-14-11-31(22(34)20(14)17)12-19(33)32-8-4-7-18(32)23(24,25)26/h3,5-6,9-10,18,28H,4,7-8,11-12H2,1-2H3	VXHZJLJJLRHGBN-UHFFFAOYSA-N	795402	US20260069571, Example 102	Discoidin domain-containing receptor 2	Homo sapiens		 550							US Patent		10.7270/Q2GQ73QH		aid1804319	US20260069571	Bhamra, I; Jones, CD; Varela Rodriguez, A; Guisot, NE	3/12/2026	7/22/2026	Redx Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=795402	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5709&target=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=795402&enzyme=Discoidin+domain-containing+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			168254012	528826865							1	MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE	6FER	Discoidin domain-containing receptor 2	DDR2_HUMAN	Q16832	Q7Z730