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Report error Found 328 of affinity data for UniProtKB/TrEMBL: C7FF05
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50351096(ASCORBIC ACID)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638529(CHEMBL5555176)
Affinity DataIC50: 1nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate pre-treated for 10 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638564(CHEMBL5426437)
Affinity DataIC50: 1nMAssay Description:Inhibition of mushroom tyrosinase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638563(CHEMBL5430416)
Affinity DataIC50: 1nMAssay Description:Inhibition of mushroom tyrosinase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 1nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured for 20 mins by absor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638521(CHEMBL5434603)
Affinity DataIC50: 1nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638565(CHEMBL5408010)
Affinity DataIC50: 1nMAssay Description:Inhibition of mushroom tyrosinase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50241222(Tectorigenin | psi-tectorigenin | CHEMBL242740)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638532(CHEMBL5567981)
Affinity DataIC50: 2nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate pre-treated for 10 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50540975(CHEBI:9428 | Tectoridin)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638543(CHEMBL5430590)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638531(CHEMBL5555631)
Affinity DataIC50: 6nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate pre-treated for 10 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638530(CHEMBL5542984)
Affinity DataIC50: 6nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate pre-treated for 10 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50635943(CHEMBL5555033)
Affinity DataIC50: 6nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by absorba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50610795(CHEMBL5289108)
Affinity DataKi:  7nMAssay Description:Binding affinity to mushroom tyrosinase assessed as binding constant by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50635941(CHEMBL5562348)
Affinity DataIC50: 9nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by absorba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638527(CHEMBL5424468)
Affinity DataIC50: 10nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638563(CHEMBL5430416)
Affinity DataKi:  10nMAssay Description:Binding affinity to mushroom tyrosinase assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50635942(CHEMBL5558420)
Affinity DataIC50: 14nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by absorba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50635939(CHEMBL5557324)
Affinity DataIC50: 14nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by absorba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638567(CHEMBL5414043)
Affinity DataIC50: 14nMAssay Description:Inhibition of mushroom tyrosinase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638526(CHEMBL5563258)
Affinity DataIC50: 15nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638514(CHEMBL5542405)
Affinity DataKi:  18nMAssay Description:Binding affinity to mushroom tyrosinase assessed as binding constant by fluorescence spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638568(CHEMBL5427541)
Affinity DataIC50: 19nMAssay Description:Inhibition of mushroom tyrosinase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50635932(CHEMBL5563317)
Affinity DataIC50: 19nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by absorba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50569812(CHEMBL4869068)
Affinity DataIC50: 20nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 20 mins followed by substrate addition incubated for 10 mins by absorban...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50241052(1,2,3,4,6-pentakis-O-(3,4,5-trihydroxybenzoyl)-bet...)
Affinity DataIC50: 20nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50241052(1,2,3,4,6-pentakis-O-(3,4,5-trihydroxybenzoyl)-bet...)
Affinity DataIC50: 20nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50651847(CHEMBL5646814)
Affinity DataIC50: 20nMAssay Description:Inhibition of mushroom Tyrosinase by using L-DOPA as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50643477(CHEMBL5575470)
Affinity DataIC50: 20nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-dopa as substrate incubated for 0.5 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638544(CHEMBL5430008)
Affinity DataIC50: 24nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50635938(CHEMBL5556099)
Affinity DataIC50: 27nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by absorba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50569806(CHEMBL4865646)
Affinity DataIC50: 30nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 20 mins followed by substrate addition incubated for 10 mins by absorban...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50570907(CHEMBL69086)
Affinity DataIC50: 30nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-dopa as substrate incubated for 0.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638534(CHEMBL5556404)
Affinity DataIC50: 33nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638536(CHEMBL5558138)
Affinity DataIC50: 34nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638537(CHEMBL5563618)
Affinity DataIC50: 35nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638533(CHEMBL5558770)
Affinity DataIC50: 36nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50643481(CHEMBL5594681)
Affinity DataIC50: 40nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-dopa as substrate incubated for 0.5 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50638523(CHEMBL5560484)
Affinity DataIC50: 50nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50570938(CHEMBL113414 | Benzooxazole-2-thiol | Benzoxazole-...)
Affinity DataKi:  58nMAssay Description:Binding affinity to mushroom tyrosinase using L-DOPA as substrate assessed as inhibition constant by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50608983(CHEMBL5271552)
Affinity DataIC50: 60nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50608983(CHEMBL5271552)
Affinity DataIC50: 60nMAssay Description:Inhibition of mushroom Tyrosinase by using L-DOPA as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50635944(CHEMBL5566780)
Affinity DataIC50: 60nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by absorba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50569799(CHEMBL4852561)
Affinity DataIC50: 60nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 20 mins followed by substrate addition incubated for 10 mins by absorban...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM23416((+)-Catechin | CHEMBL311498 | (2R,3S)-2-(3,4-dihyd...)
Affinity DataIC50: 60nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50570907(CHEMBL69086)
Affinity DataIC50: 60nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activity using L-tyrosine as substrate incubated for 0.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50330795(2-hydroxy-5-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataKi:  70nMAssay Description:Binding affinity to mushroom Tyrosinase using L-DOPA as substrate assessed as inhibition constant by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM23416((+)-Catechin | CHEMBL311498 | (2R,3S)-2-(3,4-dihyd...)
Affinity DataIC50: 70nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50643479(CHEMBL5566100)
Affinity DataIC50: 70nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-dopa as substrate incubated for 0.5 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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