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Report error Found 9 of affinity data for UniProtKB/TrEMBL: O15440
TargetATP-binding cassette sub-family C member 5(Human)
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50017103(9,10-Dimethoxy-3-methyl-2-(2,4,6-trimethyl-phenyli...)
Affinity DataIC50: 3.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 5(Human)
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM23620(Dipyridamine | SMR000058382 | MLS000028420 | CHEMB...)
Affinity DataIC50: 3.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 5(Human)
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50001285(3-(((3-(2-(7-chloroquinoline-2-yl)ethenyl)phenyl)(...)
Affinity DataIC50: 4.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 5(Human)
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50017691(CHEMBL126075 | dilazep)
Affinity DataIC50: 5.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 5(Human)
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 8.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 5(Human)
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50237626(CHEBI:9342 | Anturan | Anturane | Sulfinpyrazone |...)
Affinity DataIC50: 1.00E+5nMAssay Description:TP_TRANSPORTER: inhibition of PMEA efflux (PMEA: 1 uM) in MRP5-expressing MDCKII cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 5(Human)
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM54115(5-[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro...)
Affinity DataKi:  65.3nMAssay Description:Inhibition of ABCC5 in human erythrocytes assessed as inhibition of ATP-mediated [3H]cGMP uptake in inside-out vesicles after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 5(Human)
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50386476(CHEMBL2047880)
Affinity DataKi:  75.3nMAssay Description:Inhibition of ABCC5 in human erythrocytes assessed as inhibition of ATP-mediated [3H]cGMP uptake in inside-out vesicles after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 5(Human)
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of ABCC5 in human erythrocytes assessed as inhibition of ATP-mediated [3H]cGMP uptake in inside-out vesicles after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed