Compile Data Set for Download or QSAR
Report error Found 62 of affinity data for UniProtKB/TrEMBL: O70370
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM50444314(CHEMBL3093935)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of mouse cathepsin-S using Z-Val-Val-Arg-AMC as substrate up to 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225125(US9328118, 26)
Affinity DataIC50: 0.610nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225138(US9328118, 39)
Affinity DataIC50: 0.610nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225225(US9328118, 158)
Affinity DataIC50: 0.620nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225209(US9328118, 141)
Affinity DataIC50: 0.650nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225128(US9328118, 29)
Affinity DataIC50: 0.660nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225109(US9328118, 6)
Affinity DataIC50: 0.690nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225119(US9328118, 19)
Affinity DataIC50: 0.700nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225156(US9328118, 72)
Affinity DataIC50: 0.730nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225154(US9328118, 70)
Affinity DataIC50: 0.760nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225123(US9328118, 24)
Affinity DataIC50: 0.800nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225127(US9328118, 28)
Affinity DataIC50: 0.810nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225139(US9328118, 40)
Affinity DataIC50: 0.850nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225202(US9328118, 122)
Affinity DataIC50: 0.870nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225203(US9328118, 135)
Affinity DataIC50: 0.890nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225185(US9328118, 105)
Affinity DataIC50: 0.910nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225190(US9328118, 110)
Affinity DataIC50: 0.910nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225148(US9328118, 54)
Affinity DataIC50: 0.940nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225129(US9328118, 30)
Affinity DataIC50: 0.970nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM50444318(CHEMBL3093940)
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse cathepsin-S using Z-Val-Val-Arg-AMC as substrate up to 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225200(US9328118, 120)
Affinity DataIC50: 1nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM50444315(CHEMBL3093934)
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse cathepsin-S using Z-Val-Val-Arg-AMC as substrate up to 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225121(US9328118, 21)
Affinity DataIC50: 1nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225107(US9328118, 3)
Affinity DataIC50: 1nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225140(US9328118, 41)
Affinity DataIC50: 1.10nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225106(US9328118, 2)
Affinity DataIC50: 1.20nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225155(US9328118, 71)
Affinity DataIC50: 1.30nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225126(US9328118, 27)
Affinity DataIC50: 1.30nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225161(US9328118, 77)
Affinity DataIC50: 1.5nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM50336041(1-methyl-6-(4-(2-(1-(oxazol-2-ylmethyl)piperidin-4...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of mouse cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM50030823(CHEMBL3342553)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of mouse cathepsin S using benzyloxycarbonyl-L-Leucyl-L-Arginine 4-Methyl-coumaryl-7-amide substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225147(US9328118, 52)
Affinity DataIC50: 1.80nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225196(US9328118, 116)
Affinity DataIC50: 1.80nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225150(US9328118, 58)
Affinity DataIC50: 2nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225144(US9328118, 47)
Affinity DataIC50: 2nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM50444313(CHEMBL3093936)
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse cathepsin-S using Z-Val-Val-Arg-AMC as substrate up to 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225117(US9328118, 15)
Affinity DataIC50: 2.10nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225152(US9328118, 66)
Affinity DataIC50: 2.10nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225171(US9328118, 88)
Affinity DataIC50: 2.30nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225163(US9328118, 79)
Affinity DataIC50: 2.5nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM50323257(1-methyl-6-(4-(pyridin-2-ylmethoxy)-3-(trifluorome...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of mouse cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of mouse cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM50323247(6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of mouse cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225122(US9328118, 23)
Affinity DataIC50: 3nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM225186(US9328118, 106)
Affinity DataIC50: 3.20nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM50030822(CHEMBL3342554)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of mouse cathepsin S using benzyloxycarbonyl-L-Leucyl-L-Arginine 4-Methyl-coumaryl-7-amide substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM50444317(CHEMBL3093932)
Affinity DataIC50: 6nMAssay Description:Inhibition of mouse cathepsin-S using Z-Val-Val-Arg-AMC as substrate up to 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of cathepsin S-mediated proteolytic cleavage of MHC2 associated invariant chain in mouse splenocytes assessed as accumulation of lip10 by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM25134(CHEMBL481170 | 7-(2-cyclohexylethyl)-6-[4-(4-acety...)
Affinity DataIC50: 10nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetCathepsin S(Mouse)
Pharma Research and Early

Curated by ChEMBL
LigandPNGBDBM19859((2S)-N-(cyanomethyl)-3-cyclohexyl-2-(phenylformami...)
Affinity DataIC50: 13nM EC50:  40nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
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