Compile Data Set for Download or QSAR
Report error Found 29 of affinity data for UniProtKB/TrEMBL: O72346
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21887(2-(phenylamino)-9-[4-(1,2,3,4-tetrahydroquinolin-1...)
Affinity DataIC50: 350nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21894(1-{4-[6-oxo-2-(phenylamino)-6,9-dihydro-3H-purin-9...)
Affinity DataIC50: 410nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21869(9-(4-hydroxybutyl)-2-(phenylsulfanyl)-6,9-dihydro-...)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21893(2-(phenylamino)-9-[4-(2-phenylpiperidin-1-yl)butyl...)
Affinity DataIC50: 550nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21870(9-(4-hydroxybutyl)-2-phenoxy-6,9-dihydro-3H-purin-...)
Affinity DataIC50: 750nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21884(9-{4-[2-(2-hydroxyethyl)piperidin-1-yl]butyl}-2-(p...)
Affinity DataIC50: 770nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21888(2-(phenylamino)-9-{4-[2-(piperidin-1-ylmethyl)pyrr...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21876(4-[6-oxo-2-(phenylamino)-6,9-dihydro-3H-purin-9-yl...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21866(CHEMBL406254 | 2-phenylamino-9-(4-hydroxybutyl)-6-...)
Affinity DataIC50: 1.30E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21882(2-(phenylamino)-9-[4-(piperidin-1-yl)butyl]-6,9-di...)
Affinity DataIC50: 1.60E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21895(9-(4-{4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hyd...)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21873(9-(3-hydroxypropyl)-2-(phenylamino)-6,9-dihydro-3H...)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21881(9-{4-[bis(prop-2-en-1-yl)amino]butyl}-2-(phenylami...)
Affinity DataIC50: 2.10E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21891(9-[4-(4-methoxypiperidin-1-yl)butyl]-2-(phenylamin...)
Affinity DataIC50: 2.30E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21892(9-[4-(3-methoxypiperidin-1-yl)butyl]-2-(phenylamin...)
Affinity DataIC50: 2.50E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21877(9-[4-(dimethylamino)butyl]-2-(phenylamino)-6,9-dih...)
Affinity DataIC50: 3.60E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21872(CHEMBL347128 | 9-(2-hydroxyethyl)-2-(phenylamino)-...)
Affinity DataIC50: 4.40E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21878(9-[4-(diethylamino)butyl]-2-(phenylamino)-6,9-dihy...)
Affinity DataIC50: 4.50E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21879(9-{4-[ethyl(methyl)amino]butyl}-2-(phenylamino)-6,...)
Affinity DataIC50: 4.70E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21880(9-{4-[bis(2-hydroxyethyl)amino]butyl}-2-(phenylami...)
Affinity DataIC50: 5.20E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21890(9-[4-(3-hydroxypiperidin-1-yl)butyl]-2-(phenylamin...)
Affinity DataIC50: 5.70E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21886(9-[4-(3,5-dimethylpiperazin-1-yl)butyl]-2-(phenyla...)
Affinity DataIC50: 7.10E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21889(9-[4-(4-hydroxypiperidin-1-yl)butyl]-2-(phenylamin...)
Affinity DataIC50: 8.20E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21875(9-(4-methoxybutyl)-2-(phenylamino)-6,9-dihydro-3H-...)
Affinity DataIC50: 1.20E+4nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21874(9-(5-hydroxypentyl)-2-(phenylamino)-6,9-dihydro-3H...)
Affinity DataIC50: 1.50E+4nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21871(9-(4-hydroxybutyl)-2-[methyl(phenyl)amino]-6,9-dih...)
Affinity DataIC50: 1.60E+4nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21883(2-(phenylamino)-9-{4-[4-(piperidin-1-yl)piperidin-...)
Affinity DataIC50: 1.65E+4nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21868(2-amino-9-(4-hydroxybutyl)-6,9-dihydro-3H-purin-6-...)
Affinity DataIC50: 6.00E+4nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21885(9-[4-(decahydroquinolin-1-yl)butyl]-2-(phenylamino...)
Affinity DataKi:  30nM ΔG°:  -44.7kJ/mole IC50: 150nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed