Compile Data Set for Download or QSAR
Report error Found 9 for UniProtKB: O88420
LigandPNGBDBM50344821(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)
Affinity DataKd:  1.80nMAssay Description:Displacement of [3H]saxitoxin from NaV in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50451447(CHEMBL4217988)
Affinity DataIC50: 5nMAssay Description:Inhibition of rat Nav1.6 expressed in HEK cells by patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50330763(2-(4-Methoxyphenyl)-4(5)-phenylimidazole | 2-(4-me...)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50392415(CHEMBL402642)
Affinity DataIC50: 2.85E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50392416(CHEMBL2151778)
Affinity DataIC50: 3.17E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50133778(2,5-Diphenyl-1H-imidazole | 2,4(5)-Diphenylimidazo...)
Affinity DataIC50: 3.22E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50392417(CHEMBL2151781)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50392418(CHEMBL2151783)
Affinity DataIC50: 5.36E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50351882(CHEMBL1825043)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed