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Report error Found 90 of affinity data for UniProtKB/TrEMBL: O88693
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50406130(CHEMBL5272946 | US20250026762, Compound 1)
Affinity DataEC50:  320nMAssay Description:Invivo inhibition of GCS in C57 mouse assessed as reduction in brain GlcCer d18:1/18:0 concentration measured after 8 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50602025(CHEMBL5181454)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50602022(CHEMBL5197585)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50602024(CHEMBL5178033)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50406134(CHEMBL5275403)
Affinity DataIC50: 17nMAssay Description:Inhibition of GCS in mouse fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50406130(CHEMBL5272946 | US20250026762, Compound 1)
Affinity DataIC50: 21nMAssay Description:Inhibition of GCS in mouse fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335382(N-Octoxypentyl-L-ido-1-deoxynojirimycin | CHEMBL16...)
Affinity DataIC50: 50nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335383(N-Heptoxypentyl-L-ido-1-deoxynojirimycin | CHEMBL1...)
Affinity DataIC50: 50nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50585893(CHEMBL5078078)
Affinity DataIC50: 51nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hr by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50312527(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-L-ido-1-deox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50312527(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-L-ido-1-deox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335384(N-Hexoxypentyl-L-ido-1-deoxynojirimycin | CHEMBL16...)
Affinity DataIC50: 100nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335387(N-Nonoxypentyl-1-deoxynojirimycin | CHEMBL1651633)
Affinity DataIC50: 100nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335385(N-Pentoxypentyl-L-ido-1-deoxynojirimycin | CHEMBL1...)
Affinity DataIC50: 150nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50585896(CHEMBL5085509)
Affinity DataIC50: 190nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hr by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335388(N-Octoxypentyl-1-deoxynojirimycin | CHEMBL1651632)
Affinity DataIC50: 200nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50: 200nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50: 200nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335389(N-Heptoxypentyl-1-deoxynojirimycin | CHEMBL1651631)
Affinity DataIC50: 300nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379037(CHEMBL2011641)
Affinity DataIC50: 800nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335390(N-Hexoxypentyl-1-deoxynojirimycin | CHEMBL1651630)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335393(N-Nonyl-L-ido-1-deoxynojirimycin | CHEMBL1651627)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335391(N-Pentoxypentyl-1-deoxynojirimycin | CHEMBL1651629)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335386(N-Butoxypentyl-L-ido-1-deoxynojirimycin | CHEMBL16...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50615552(CHEMBL5266608)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of GSG in mouse MEB5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM18358((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335395(N-Heptyl-L-ido-1-deoxynojirimycin | CHEMBL1651555)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335394(N-Octyl-L-ido-1-deoxynojirimycin | CHEMBL1651626)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50335392(N-Butoxypentyl-1-deoxynojirimycin | CHEMBL1651628)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50242629(N-butylgalactonojirimycin | CHEMBL485842)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition mouse glucosylceramide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379059(CHEMBL2011601)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379050(CHEMBL2011622)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379051(CHEMBL2011624)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50240725((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | F...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379052(CHEMBL2011625)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379053(CHEMBL2011626)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379054(CHEMBL1818438)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379055(CHEMBL2011628)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50350760(CHEMBL1818436)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379056(CHEMBL2011629)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379057(CHEMBL2011630)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379058(CHEMBL2011623)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379067(CHEMBL2011609)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379041(CHEMBL2011612)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379060(CHEMBL505237)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379069(CHEMBL2011610)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379061(CHEMBL2011602)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379062(CHEMBL2011603)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50379063(CHEMBL2011604)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
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