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TargetCoagulation factor IX/VIII(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565732BDBM50565732(CHEMBL4782167)
Affinity DataIC50: 14nMAssay Description:Inhibition of human citrated plasma iXase (factor 8a-factor 9a complex) preincubated for 2 mins followed by factor 10 addition and measured after 1 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetCoagulation factor IX/VIII(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565731BDBM50565731(CHEMBL4786745)
Affinity DataIC50: 17nMAssay Description:Inhibition of human citrated plasma iXase (factor 8a-factor 9a complex) preincubated for 2 mins followed by factor 10 addition and measured after 1 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetCoagulation factor IX/VIII(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458155BDBM50458155(CHEMBL4210593)
Affinity DataIC50: 98.7nMAssay Description:Inhibition of human intrinsic factor tenase using factor-10 as substrate preincubated for 2 mins followed by substrate addition for 1 min measured ev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor IX/VIII(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458157BDBM50458157(CHEMBL4216002)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human intrinsic factor tenase using factor-10 as substrate preincubated for 2 mins followed by substrate addition for 1 min measured ev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59162BDBM59162(8047577)
Affinity DataIC50: 2.10E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59159BDBM59159(6190013)
Affinity DataIC50: 2.11E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor IX/VIII(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458156BDBM50458156(CHEMBL4204328)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of human intrinsic factor tenase using factor-10 as substrate preincubated for 2 mins followed by substrate addition for 1 min measured ev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59162BDBM59162(8047577)
Affinity DataIC50: 2.44E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59162BDBM59162(8047577)
Affinity DataIC50: 2.56E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor IX/VIII(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565730BDBM50565730(CHEMBL4792554)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human citrated plasma iXase (factor 8a-factor 9a complex) preincubated for 2 mins followed by factor 10 addition and measured after 1 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59164BDBM59164(8048422)
Affinity DataIC50: 3.89E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59164BDBM59164(8048422)
Affinity DataIC50: 4.17E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59154BDBM59154(5739991)
Affinity DataIC50: 4.63E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59163BDBM59163(6789536)
Affinity DataIC50: 4.81E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59161BDBM59161(5738875)
Affinity DataIC50: 5.00E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59163BDBM59163(6789536)
Affinity DataIC50: 5.60E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59161BDBM59161(5738875)
Affinity DataIC50: 5.65E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59163BDBM59163(6789536)
Affinity DataIC50: 5.85E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59165BDBM59165(8056354)
Affinity DataIC50: 6.29E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59165BDBM59165(8056354)
Affinity DataIC50: 6.51E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59153BDBM59153(5737176)
Affinity DataIC50: 6.66E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59164BDBM59164(8048422)
Affinity DataIC50: 6.70E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59165BDBM59165(8056354)
Affinity DataIC50: 6.80E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59161BDBM59161(5738875)
Affinity DataIC50: 6.83E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59159BDBM59159(6190013)
Affinity DataIC50: 7.50E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 50423622BDBM50423622(CHEMBL1614804)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human factor 8 binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59159BDBM59159(6190013)
Affinity DataIC50: 8.48E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59153BDBM59153(5737176)
Affinity DataIC50: 8.50E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 50376417BDBM50376417(CHEMBL261865)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human factor 8 binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59153BDBM59153(5737176)
Affinity DataIC50: 9.25E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59154BDBM59154(5739991)
Affinity DataIC50: 1.04E+4nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59154BDBM59154(5739991)
Affinity DataIC50: 1.17E+4nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59157BDBM59157(6126765)
Affinity DataIC50: 1.19E+4nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59160BDBM59160(6209549)
Affinity DataIC50: 1.24E+4nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59155BDBM59155(5924029)
Affinity DataIC50: 2.45E+4nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59156BDBM59156(cid_726942 | 6072484)
Affinity DataIC50: 2.68E+4nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59152BDBM59152(5523453)
Affinity DataIC50: 2.77E+4nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 50425649BDBM50425649(CHEMBL2315239)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human FVIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59158BDBM59158(6168356)
Affinity DataIC50: 4.96E+4nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 50425648BDBM50425648(CHEMBL2315243)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human FVIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandChemical structure of BindingDB Monomer ID 59151BDBM59151(5247489)
Affinity DataIC50: 5.61E+4nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed