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TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM35997(1,4-dioxo-1,2,3,4-tetrahydro-1,2,3-benzothiadiazin...)
Affinity DataKd:  3.89E+4nM Kon:  4.99E+4M-1s-1 Koff:  1.94s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKd:  4.26E+3nM Kon:  1.43E+5M-1s-1 Koff:  0.611s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM35999(2-methylbenzene-1-sulfonamide | SPR_3)
Affinity DataKd:  2.18E+3nM Kon:  1.10E+5M-1s-1 Koff:  0.240s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36000(3,5-dichlorobenzene-1-sulfonamide | SPR_4)
Affinity DataKd:  287nM Kon:  9.02E+5M-1s-1 Koff:  0.259s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36001(6-aminopyridine-3-sulfonamide | SPR_5)
Affinity DataKd:  1.08E+4nM Kon:  1.88E+4M-1s-1 Koff:  0.203s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36002(2,3-dihydro-1,4-benzodioxine-6-sulfonamide | SPR_6)
Affinity DataKd:  817nM Kon:  1.34E+5M-1s-1 Koff:  0.109s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36003(1-methyl-1H-imidazole-4-sulfonamide | SPR_7)
Affinity DataKd:  3.53E+4nM Kon:  4.65E+3M-1s-1 Koff:  0.164s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36004(2,4-difluorobenzene-1-sulfonamide | SPR_8)
Affinity DataKd:  394nM Kon:  2.72E+5M-1s-1 Koff:  0.107s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36005(2,3-dihydro-1H-indole-5-sulfonamide | SPR_9)
Affinity DataKd:  3.11E+3nM Kon:  1.88E+4M-1s-1 Koff:  0.0585s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36006(2-oxo-1-propyl-2,3-dihydro-1H-1,3-benzodiazole-5-s...)
Affinity DataKd:  197nM Kon:  4.75E+5M-1s-1 Koff:  0.0935s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36007(3-chloro-5-fluoro-2-methylbenzene-1-sulfonamide | ...)
Affinity DataKd:  96.8nM Kon:  7.88E+5M-1s-1 Koff:  0.0763s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36008(2-amino-1,3-benzothiazole-6-sulfonamide | SPR_12)
Affinity DataKd:  383nM Kon:  5.10E+4M-1s-1 Koff:  0.0196s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50210909(3-chlorobenzimidazo[1,2-c][1,2,3]thiadiazole-7-sul...)
Affinity DataKd:  141nMAssay Description:Binding affinity to bovine CA2 by typical isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50210908(3-morpholinbenzimidazo[1,2-c][1,2,3]thiadiazole-7-...)
Affinity DataKd:  38nMAssay Description:Binding affinity to bovine CA2 by typical isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50210907(3-methylsulfonylbenzimidazo[1,2-c][1,2,3]thiadiazo...)
Affinity DataKd:  500nMAssay Description:Binding affinity to bovine CA2 by typical isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50210912(3-phenylthiobenzimidazo[1,2-c][1,2,3]thiadiazol-7-...)
Affinity DataKd:  285nMAssay Description:Binding affinity to bovine CA2 by typical isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50210913(3-(N-methylpiperazin)benzimidazo[1,2-c][1,2,3]thia...)
Affinity DataKd:  391nMAssay Description:Binding affinity to bovine CA2 by typical isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50210910(3-methylthiobenzimidazo[1,2-c][1,2,3]thiadiazole-7...)
Affinity DataKd:  322nMAssay Description:Binding affinity to bovine CA2 by typical isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50210911(benzimidazo[1,2-c][1,2,3]thiadiazole-7-sulfonamide...)
Affinity DataKd:  286nMAssay Description:Binding affinity to bovine CA2 by typical isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50236140(4-ethynyl benzene sulfonamide | 4-ethynylbenzenesu...)
Affinity DataKd:  37nMAssay Description:Inhibition of bovine carbonic anhydrase2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50271035((S)-4-(1-(1-(3-aza-bicyclo[3.2.2]nonan-3-yl)-3-met...)
Affinity DataKd:  0.200nMAssay Description:Inhibition of bovine carbonic anhydrase2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM4703(4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic...)
Affinity DataKd:  890nMAssay Description:Binding affinity to bovine carbonic anhydrase-2 assessed as dissociation constant by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM10857(aromatic sulfonamide compound 5 | CHEMBL21 | 4-ami...)
Affinity DataKd:  5.88E+3nMAssay Description:Binding affinity to bovine carbonic anhydrase-2 assessed as dissociation constant by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50236140(4-ethynyl benzene sulfonamide | 4-ethynylbenzenesu...)
Affinity DataKd:  37nMAssay Description:Binding affinity to bovine carbonic anhydrase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50514428(CHEMBL4450233)
Affinity DataKd:  0.5nMAssay Description:Binding affinity to bovine carbonic anhydrase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50044311(Trifluoro-methanesulfonamide | TRIFLUOROMETHANE SU...)
Affinity DataIC50: 2nMAssay Description:Inhibition of bovine carbonic anhydrase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50004262(CHEMBL1438301)
Affinity DataIC50: 11nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50068231(CHEMBL3403326)
Affinity DataIC50: 35nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50004258(CHEMBL3237498)
Affinity DataIC50: 52nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50068223(CHEMBL3403323)
Affinity DataIC50: 57nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50175007(phenyldifluoromethanesulfonamide | CHEMBL371870)
Affinity DataIC50: 58nMAssay Description:Inhibition of bovine carbonic anhydrase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM16661(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Affinity DataIC50: 100nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50068229(CHEMBL3403327)
Affinity DataIC50: 100nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50068225(CHEMBL3403324)
Affinity DataIC50: 134nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50068227(CHEMBL3403325)
Affinity DataIC50: 152nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 180nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataIC50: 215nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50004252(CHEMBL3237493)
Affinity DataIC50: 220nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50517903(CHEMBL4542353)
Affinity DataIC50: 220nMAssay Description:Inhibition of bovine carbonic anhydrase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50068226(CHEMBL1607835)
Affinity DataIC50: 241nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50004255(CHEMBL1330833)
Affinity DataIC50: 490nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50068218(CHEMBL3403318)
Affinity DataIC50: 544nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50175005(phenylmethanesulfonamide | CHEMBL369953)
Affinity DataIC50: 630nMAssay Description:Inhibition of bovine carbonic anhydrase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50044318(CHEMBL305268 | aminosulfane dioxide | METHANESULFO...)
Affinity DataIC50: 650nMAssay Description:Inhibition of bovine carbonic anhydrase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50068221(CHEMBL3403321)
Affinity DataIC50: 656nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50068228(CHEMBL3403317)
Affinity DataIC50: 691nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50068220(CHEMBL3403320)
Affinity DataIC50: 821nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 960nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 960nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM50004260(CHEMBL3237499)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
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