Compile Data Set for Download or QSAR
Report error Found 647 of affinity data for UniProtKB/TrEMBL: P0DPI0
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM43865(6-formyl-4,7-dihydroxy-9-oxo-5H-phenazine-1-carbox...)
Affinity DataEC50:  1.31E+5nMAssay Description:Inhibition of Clostridium botulinum neurotoxin serotype A light chain in Sprague-Dawley rat cerebellar granule cells assessed as protection against S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50445590(CHEMBL3103445)
Affinity DataEC50: >1.00E+6nMAssay Description:Inhibition of Clostridium botulinum Hall A hyper BoNT/A light chain expressed in human induced pluripotent stem cell-derived neurons after 8 hrs by W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50445591(CHEMBL3103462)
Affinity DataEC50: >3.00E+5nMAssay Description:Inhibition of Clostridium botulinum Hall A hyper BoNT/A light chain expressed in human induced pluripotent stem cell-derived neurons after 8 hrs by W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50445592(CHEMBL3103461)
Affinity DataEC50:  1.98E+5nMAssay Description:Inhibition of Clostridium botulinum Hall A hyper BoNT/A light chain expressed in human induced pluripotent stem cell-derived neurons after 8 hrs by W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50445593(CHEMBL3103460)
Affinity DataEC50:  2.09E+5nMAssay Description:Inhibition of Clostridium botulinum Hall A hyper BoNT/A light chain expressed in human induced pluripotent stem cell-derived neurons after 8 hrs by W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50445594(CHEMBL3103459)
Affinity DataEC50: >3.00E+5nMAssay Description:Inhibition of Clostridium botulinum Hall A hyper BoNT/A light chain expressed in human induced pluripotent stem cell-derived neurons after 8 hrs by W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50100895(2-(4-(4-carbamimidoylphenoxy)phenyl)-1H-indole-6-c...)
Affinity DataKd:  4.60E+3nMAssay Description:Binding affinity to Clostridium botulinum neurotoxin A light chain at 390 uM by isothermal titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50067697(7-chloro-N-(3-(3-(7-chloroquinolin-4-ylamino)propy...)
Affinity DataIC50: 26nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50429171(CHEMBL2336714)
Affinity DataIC50: 30nMAssay Description:Inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAPtide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50429170(CHEMBL2336715)
Affinity DataIC50: 40nMAssay Description:Inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAPtide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50447108(CHEMBL3112881)
Affinity DataIC50: 150nMAssay Description:Inhibition of Clostridium botulinum recombinant BoNT/A light chain using N-terminal acetylated, C-terminal aminated SNAP-25 (187-203) as substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50429175(CHEMBL2336718)
Affinity DataIC50: 200nMAssay Description:Inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAPtide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50383525(CHEMBL2032269)
Affinity DataIC50: 230nMAssay Description:Inhibition of clostridium botulinum Botulinum neurotoxin type A using SNAPide as substrate by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50429172(CHEMBL2336713)
Affinity DataIC50: 250nMAssay Description:Inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAPtide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50429178(CHEMBL2336712)
Affinity DataIC50: 250nMAssay Description:Inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAPtide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50589492(CHEMBL5171667)
Affinity DataIC50: 270nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain (1 to 424 residues) using SNAPtide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50429180(CHEMBL2336710)
Affinity DataIC50: 300nMAssay Description:Inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAPtide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50576781(CHEMBL4860434)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal 6XHis-tagged Clostridium botulinum BoNT/A light chain C-terminal truncation mutant (1 to 425 residues) expressed in Escheric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50576781(CHEMBL4860434)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal 6XHis-tagged Clostridium botulinum BoNT/A light chain C-terminal truncation mutant (1 to 425 residues) expressed in Escheric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM23274(BMCL176463 Compound 2 | BMC173072 Compound 2 | (2E...)
Affinity DataIC50: 300nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain using SNAPtide as substrate by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50576781(CHEMBL4860434)
Affinity DataIC50: 340nMAssay Description:Inhibition of N-terminal 6XHis-tagged Clostridium botulinum BoNT/A light chain C-terminal truncation mutant (1 to 425 residues) expressed in Escheric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50429176(CHEMBL2336717)
Affinity DataIC50: 400nMAssay Description:Inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAPtide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM23274(BMCL176463 Compound 2 | BMC173072 Compound 2 | (2E...)
Affinity DataIC50: 400nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain using SNAPtide as substrate by HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM23274(BMCL176463 Compound 2 | BMC173072 Compound 2 | (2E...)
Affinity DataIC50: 410nMAssay Description:Inhibition of Clostridium botulinum BoNT/AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM23274(BMCL176463 Compound 2 | BMC173072 Compound 2 | (2E...)
Affinity DataIC50: 410nMAssay Description:Inhibition of Clostridium botulinum toxin BoNT/A light chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM23274(BMCL176463 Compound 2 | BMC173072 Compound 2 | (2E...)
Affinity DataIC50: 410nMAssay Description:Inhibition of protease activity of Clostridium botulinum BoNT/A using SNAP-25 as substrate by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM23274(BMCL176463 Compound 2 | BMC173072 Compound 2 | (2E...)
Affinity DataIC50: 410nMAssay Description:Inhibition of Clostridium botulinum BoNT/AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50589504(CHEMBL5202691)
Affinity DataIC50: 420nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50429177(CHEMBL2336716)
Affinity DataIC50: 500nMAssay Description:Inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAPtide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50429173(CHEMBL2336709)
Affinity DataIC50: 500nMAssay Description:Inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAPtide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50308030(CHEMBL599255 | cid_2977478 | 5-chloro-7-((4-ethoxy...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Clostridium botulinum toxin BoNT/A light chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50589500(CHEMBL5208729)
Affinity DataIC50: 500nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain (1 to 424 residues) using SNAPtide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50383533(CHEMBL2032254)
Affinity DataIC50: 550nMAssay Description:Inhibition of clostridium botulinum Botulinum neurotoxin type A using SNAPide as substrate by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50383550(CHEMBL2032381)
Affinity DataIC50: 560nMAssay Description:Inhibition of clostridium botulinum Botulinum neurotoxin type A using SNAPide as substrate by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50561055(CHEMBL4742073)
Affinity DataIC50: 587nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain using SNAPtide as substrate preincubated with enzyme for 2 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50445604(CHEMBL3103448)
Affinity DataIC50: 590nMAssay Description:Inhibition of N-terminal 6XHis-tagged Clostridium botulinum BoNT/A light chain C-terminal truncation mutant (1 to 425 residues) expressed in Escheric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50445604(CHEMBL3103448)
Affinity DataIC50: 590nMAssay Description:Inhibition of N-terminal 6XHis-tagged Clostridium botulinum BoNT/A light chain C-terminal truncation mutant (1 to 425 residues) expressed in Escheric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50234245(CHEMBL4060854)
Affinity DataIC50: 600nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50234255(CHEMBL4091467)
Affinity DataIC50: 600nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50383556(CHEMBL2032387)
Affinity DataIC50: 610nMAssay Description:Inhibition of clostridium botulinum Botulinum neurotoxin type A using SNAPide as substrate by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50013665(CHEMBL3264507)
Affinity DataIC50: 630nMAssay Description:Inhibition of Clostridium botulinum recombinant BoNT/A light chain using N-terminal acetylated, C-terminal aminated SNAP-25 (187-203) as substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50383532(CHEMBL2032249)
Affinity DataIC50: 640nMAssay Description:Inhibition of clostridium botulinum Botulinum neurotoxin type A using SNAPide as substrate by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50383552(CHEMBL2032383)
Affinity DataIC50: 660nMAssay Description:Inhibition of clostridium botulinum Botulinum neurotoxin type A using SNAPide as substrate by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM23274(BMCL176463 Compound 2 | BMC173072 Compound 2 | (2E...)
Affinity DataIC50: 670nMAssay Description:Inhibition of Clostridium botulinum recombinant BoNT/A light chain using N-terminal acetylated, C-terminal aminated SNAP-25 (187-203) as substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM23274(BMCL176463 Compound 2 | BMC173072 Compound 2 | (2E...)
Affinity DataIC50: 670nMAssay Description:Inhibition of clostridium botulinum Botulinum neurotoxin type A using SNAPide as substrate by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50383527(CHEMBL2032250)
Affinity DataIC50: 690nMAssay Description:Inhibition of clostridium botulinum Botulinum neurotoxin type A using SNAPide as substrate by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50234257(CHEMBL4089872)
Affinity DataIC50: 700nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM52237(2-methyl-7-[phenyl-(pyridin-2-ylamino)methyl]quino...)
Affinity DataIC50: 700nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50234270(CHEMBL4071334)
Affinity DataIC50: 700nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
TBA

Curated by ChEMBL
LigandPNGBDBM50234272(CHEMBL4084638)
Affinity DataIC50: 700nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
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