Report error Found 326 of affinity data for UniProtKB/TrEMBL: P23526
Displayed 1 to 50 (of 326 total ) | Next | Last >>
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Inhibition of SAH hydrolase (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Compound was tested for inhibition of S-adenosyl homocysteine (SAH) hydrolase. More data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 minsMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Compound was tested for inhibition of S-adenosyl homocysteine (SAH) hydrolase. More data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Evaluated for the 50% inhibition of bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolaseMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Inhibitory activity against bovine liver S-adenosyl-L-homocysteine hydrolase (AdoHcy) rate of inactivation by NpcAMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Time course of inactivation of bovine liver S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity against S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Tested for inhibitory concentration against S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of S-adenosyl-homocysteine (AdoHcy)hydrolase from rabbit erythrocytesMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibitory activity against bovine liver S-adenosyl-L-homocysteine hydrolase (AdoHcy) rate of inactivation by NpcAMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 15.2nMAssay Description:Inhibitory activity against S-adenosyl-L-homocysteine hydrolase from rabbit erythrocytesMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 15.2nMAssay Description:Inhibitory effect against S-adenosyl-L-homocysteine hydrolase of rabbit erythrocyte.More data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 minsMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Tested for inhibitory concentration against S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Inhibitory activity against bovine liver S-adenosyl-L-homocysteine hydrolase (AdoHcy) rate of inactivation by NpcAMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 minsMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Inhibitory activity against bovine liver S-adenosyl-L-homocysteine hydrolase (AdoHcy) rate of inactivation by NpcAMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Tested for inhibitory concentration against S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Time course of inactivation of bovine liver S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Inhibition of S-adenosyl-L-homocysteine hydrolase, inactivation rate constant.More data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:concentration dependent inhibition of S-Adenosyl-homocysteine hydrolase was determined by Kitz and Wilson methodMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Binding affinity towards purified recombinant human placental S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of S-adenosyl-homocysteine (AdoHcy)hydrolase from rabbit erythrocytesMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 minsMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:Time course of inactivation of bovine liver S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Binding affinity towards purified recombinant human placental S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:concentration dependent inhibition of S-Adenosyl-homocysteine hydrolase was determined by Kitz and Wilson methodMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Human)
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 49nMAssay Description:Inhibitory activity against bovine liver S-adenosyl-L-homocysteine hydrolase (AdoHcy) rate of inactivation by NpcAMore data for this Ligand-Target Pair





3D Structure (crystal)






















