Compile Data Set for Download or QSAR
Report error Found 613 for UniProtKB: P29473
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50437696(CHEMBL2408677)
Affinity DataEC50:  0.00600nMAssay Description:Activation of eNOS in BCAEC assessed as increase in nitric oxide level after 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50437697(CHEMBL2408678)
Affinity DataEC50:  1nMAssay Description:Activation of eNOS in BCAEC assessed as increase in nitric oxide level after 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM23417(cid_72276 | (-)-Epicatechin | (2R,3R)-2-(3,4-dihyd...)
Affinity DataEC50:  2nMAssay Description:Activation of eNOS in BCAEC assessed as increase in nitric oxide level after 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM228656(TTATVTKYWF | CAV (90-99) F92A)
Affinity DataKd:  23nMpH: 7.5 T: 2°CAssay Description:eNOS was diluted to varying concentrations in buffer containing 50 mM inorganic phosphate, 50 mM KCl, and 5 mM DTT, pH 7.5. A spectrophotometer was u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM228655(TTFTVTKYWF | CAV (90-99))
Affinity DataKd:  42nMpH: 7.5 T: 2°CAssay Description:eNOS was diluted to varying concentrations in buffer containing 50 mM inorganic phosphate, 50 mM KCl, and 5 mM DTT, pH 7.5. A spectrophotometer was u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50258602(CHEMBL4068062)
Affinity DataKi:  92nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50258601(CHEMBL4089246)
Affinity DataKi:  115nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50258603(CHEMBL4090184)
Affinity DataKi:  273nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50095181(N-(3-Aminomethyl-phenyl)-furan-2-carboxamidine | C...)
Affinity DataKi:  350nMAssay Description:Inhibition against endothelial Nitric Oxide Synthase(eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50095172(N-(3-Aminomethyl-phenyl)-thiophene-2-carboxamidine...)
Affinity DataKi:  460nMAssay Description:Inhibition against endothelial Nitric Oxide Synthase(eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50258687(CHEMBL4092027)
Affinity DataKi:  468nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50138977(N-(3-Aminomethyl-phenyl)-acetamidine | N-(3-Aminom...)
Affinity DataIC50: 480nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50449048(CHEMBL3126213 | US9212144, 5 (Ex. 8))
Affinity DataKi:  485nMpH: 7.4Assay Description:To test for enzyme inhibition, the hemoglobin capture assay was used to measure nitric oxide production. The assay was performed at 37° C. in HEPES b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50449048(CHEMBL3126213 | US9212144, 5 (Ex. 8))
Affinity DataKi:  485nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli using L-arginine as substrate assessed as NO production by hemoglobin capture ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50095177(CHEMBL503356 | CHEMBL542185 | Pyrazole-1-carboxami...)
Affinity DataKi:  500nMAssay Description:Inhibition against endothelial Nitric Oxide Synthase(eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50258722(CHEMBL4092616)
Affinity DataKi:  562nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50258688(CHEMBL4062164)
Affinity DataKi:  581nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50225106(NG-nitroarginine | 2-Amino-5-(N'-nitro-guanidino)-...)
Affinity DataKi:  720nM ΔG°:  -35.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50203163((S)-2-((S)-4-amino-2-((S)-2,4-diamino-4-oxobutanam...)
Affinity DataKi:  720nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50225106(NG-nitroarginine | 2-Amino-5-(N'-nitro-guanidino)-...)
Affinity DataKi:  750nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50061232(2-Amino-5-(N'-prop-2-ynyl-guanidino)-pentanoic aci...)
Affinity DataKi:  810nMAssay Description:Compound was tested for binding affinity against Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50448833(CHEMBL3125048)
Affinity DataKi:  900nMAssay Description:Inhibition of recombinant bovine eNOS overexpressed in Escherichia coli using L-arginine as substrate assessed as nitric oxide formation measured for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM196648(US9212144, 3 | US9242957, 65)
Affinity DataKi:  900nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50448833(CHEMBL3125048)
Affinity DataKi:  900nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli using L-arginine as substrate assessed as NO production by hemoglobin capture ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM196648(US9212144, 3 | US9242957, 65)
Affinity DataKi:  900nMpH: 7.4Assay Description:To test for enzyme inhibition, the hemoglobin capture assay was used to measure nitric oxide production. The assay was performed at 37° C. in HEPES b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50438638(CHEMBL2414426)
Affinity DataKi:  979nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50030171(5-{[amino(hydrazino)methyl]amino}-2-ammoniopentano...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for its inhibitory activity against endothelial NO2- synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50258623(CHEMBL4071836)
Affinity DataKi:  1.04E+3nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM202653(US9242957, QJ-III-33)
Affinity DataKi:  1.15E+3nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
Go to US Patent

TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50023386(CHEMBL3327299)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of bovine eNOS using L-arginine substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial [1-973,L111A](Bovine)
University of California Irvine

LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  1.18E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50225106(NG-nitroarginine | 2-Amino-5-(N'-nitro-guanidino)-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity of conversion of radiolabeled arginine to citrulline by isomeric form of nitric oxide synthase Endothelial nitric oxide synthase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50258600(CHEMBL4064297)
Affinity DataKi:  1.22E+3nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50341684(NOS Inhibitor, 3h | CHEMBL1766633 | 6,6'-(2,2'-(1,...)
Affinity DataKi:  1.41E+3nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
Go to US Patent

TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50341684(NOS Inhibitor, 3h | CHEMBL1766633 | 6,6'-(2,2'-(1,...)
Affinity DataKi:  1.41E+3nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM202649(US9242957, QJ-II-195)
Affinity DataKi:  1.45E+3nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
Go to US Patent

TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM152720(N-[3-({[(3S,5S)-5-({[3-(thiophene-2-imidamido)phen...)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of bovine eNOS using L-arginine substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50341686(6,6'-(2,2'-(Naphthalene-2,7-diyl)bis(ethane-2,1-di...)
Affinity DataKi:  1.52E+3nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50060407(CHEMBL3394387)
Affinity DataKi:  1.56E+3nMAssay Description:Inhibition of bovine eNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50258650(CHEMBL4100356)
Affinity DataKi:  1.57E+3nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  1.60E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50341687(6,6'-(2,2'-(Naphthalene-2,6-diyl)bis(ethane-2,1-di...)
Affinity DataKi:  1.74E+3nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50258622(CHEMBL4097898)
Affinity DataKi:  1.86E+3nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM202655(US9242957, QJ-III-21)
Affinity DataKi:  1.86E+3nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
Go to US Patent

TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50023385(CHEMBL3327300)
Affinity DataKi:  1.86E+3nMAssay Description:Inhibition of bovine eNOS using L-arginine substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50270528(3-bromo-7-nitro-1H-indazole | 3-BROMO-7-NITROINDAZ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50438645(CHEMBL2414428)
Affinity DataKi:  2.15E+3nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50446252(CHEMBL3109186 | US9732037, Compound 6)
Affinity DataKi:  2.18E+3nMAssay Description:Inhibition of bovine recombinant eNOS overexpressed in Escherichia coli using L-arginine as substrate assessed as formation of NO-hemoglobin complex ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50448825(CHEMBL3128245)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of recombinant bovine eNOS overexpressed in Escherichia coli using L-arginine as substrate assessed as nitric oxide formation measured for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM202643(US9242957, 7)
Affinity DataKi:  2.20E+3nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
Go to US Patent

Displayed 1 to 50 (of 613 total ) | Next | Last >>
Jump to: