Compile Data Set for Download or QSAR
Report error Found 67 of affinity data for UniProtKB/TrEMBL: P30098
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50299467((5S,8S,14S,17S,20S,23S,26S,29S,32S)-26-((1H-imidaz...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at guinea pig NK3 receptor expressed in cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50291261(SR-14280 | SR-142801 | (S)-(+)-N-((3-[1-Benzoyl-3-...)
Affinity DataKd:  0.0800nMAssay Description:Apparent binding affinity to guinea pig NK3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50291261(SR-14280 | SR-142801 | (S)-(+)-N-((3-[1-Benzoyl-3-...)
Affinity DataKd:  0.150nMAssay Description:Equilibrium binding affinity to guinea pig NK3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50007963(CHEMBL441061 | pGlu6-Phe-Phe-Gly-Leu-Met-NH2)
Affinity DataEC50:  5nMAssay Description:Effective dose was measured on NK3 receptors of guinea pig ileum for maximal contraction in the presence of 10e-7 M substance P methyl ester.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50007972(CHEMBL311917 | pGlu6-Phe-Phe8(psi)CH2O-Gly-Leu-Met...)
Affinity DataEC50:  13nMAssay Description:Effective dose was measured on NK3 receptors of guinea pig ileum for maximal contraction in the presence of 10e-7 M substance P methyl ester.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50007962(CHEMBL81919 | pGlu6-Phe-NMePhe-Gly-Leu-Met-NH2)
Affinity DataEC50:  0.900nMAssay Description:Effective dose was measured on NK3 receptors of guinea pig ileum for maximal contraction in the presence of 10e-7 M substance P methyl ester.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50403793(CHEMBL2115415)
Affinity DataIC50: 0.720nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50079412((NKB)Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2 |...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125 I][MePhe7]-NKBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50090485(spiro[(2-hydroxy)indane-1,40-piperidine] analogue ...)
Affinity DataIC50: 2.70nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50050641([(R)-2-(2,3-Difluoro-phenyl)-1-methyl-1-(7-ureido-...)
Affinity DataIC50: 3.70nMAssay Description:Compound was tested for binding affinity towards Tachykinin receptor 3 binding sites in guinea pig cortical membranes using [125I][MePhe7]-NKB as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50050641([(R)-2-(2,3-Difluoro-phenyl)-1-methyl-1-(7-ureido-...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125 I]-[MePhe7]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50050649({(S)-1-[(R)-1-Methyl-2-phenyl-1-(7-ureido-heptylca...)
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125 I]-[MePhe7]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50050649({(S)-1-[(R)-1-Methyl-2-phenyl-1-(7-ureido-heptylca...)
Affinity DataIC50: 9nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50079412((NKB)Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2 |...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against binding of [125I][MePhe7]-NKB SP to tachykinin NK-3 receptor in guinea pig cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50403790(CHEMBL2114963)
Affinity DataIC50: 11nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50052524((S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-m...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125I]-[MePhe7]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50050652([(R)-2-(2-Fluoro-phenyl)-1-methyl-1-(7-ureido-hept...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125 I]-[MePhe7]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50050652([(R)-2-(2-Fluoro-phenyl)-1-methyl-1-(7-ureido-hept...)
Affinity DataIC50: 14nMAssay Description:Compound was tested for binding affinity towards Tachykinin receptor 3 binding sites in guinea pig cortical membranes using [125I]-[MePhe7]-Neurokini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50282774({(S)-1-[(R)-1-(8-Carbamoyl-octylcarbamoyl)-2-pheny...)
Affinity DataIC50: 15nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50090487(spiro[(2-hydroxy)indane-1,40-piperidine] analogue ...)
Affinity DataIC50: 17nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175494(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataIC50: 21nMAssay Description:NK3 IC50 determined using [125I]bolton Hunter labeled eledoisin at NK3 receptors from guinea pig cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50050642({(S)-1-[(R)-1-(8-Hydroxy-octylcarbamoyl)-1-methyl-...)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125 I][MePhe7]-NKBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50282782({(S)-1-[(R)-1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-...)
Affinity DataIC50: 22nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50071484(N-[(R)-4-(4-Acetylamino-4-phenyl-piperidin-1-yl)-2...)
Affinity DataIC50: 208nMAssay Description:NK3 IC50 determined using [125I]bolton Hunter labeled eledoisin at NK3 receptors from guinea pig cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50283257((S)-2-[2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-4...)
Affinity DataIC50: 276nMAssay Description:Concentration producing half-maximal inhibition of specific binding of [3H]senktide to Tachykinin receptor 3 in the guinea pig cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50291261(SR-14280 | SR-142801 | (S)-(+)-N-((3-[1-Benzoyl-3-...)
Affinity DataIC50: 320nMAssay Description:Ability to displace [3H]senktide succinyl-[Asp9MePhe8]-SP (6-13)} from Tachykinin receptor 3 of guinea pig cerebral cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50403791(CHEMBL2114965)
Affinity DataIC50: 520nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50283253((S)-2-[2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-4...)
Affinity DataIC50: 533nMAssay Description:Concentration producing half-maximal inhibition of specific binding of [3H]senktide to Tachykinin receptor 3 in the guinea pig cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50403792(CHEMBL2115416)
Affinity DataIC50: 660nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50001450(Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met NH2 | ...)
Affinity DataIC50: 717nMAssay Description:Inhibitory activity against binding of [125I][MePhe7]-NKB SP to tachykinin NK-3 receptor in guinea pig cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50283250((S)-2-[2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-4...)
Affinity DataIC50: 882nMAssay Description:Concentration producing half-maximal inhibition of specific binding of [3H]senktide to Tachykinin receptor 3 in the guinea pig cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50090482(spiro[(2-hydroxy)indane-1,40-piperidine] analogue ...)
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50090484(spiro[(2-hydroxy)indane-1,40-piperidine] analogue ...)
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50283252((S)-2-[2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-carba...)
Affinity DataIC50: 1.13E+3nMAssay Description:Concentration producing half-maximal inhibition of specific binding of [3H]senktide to Tachykinin receptor 3 in the guinea pig cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50050675([(S)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2...)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibitory activity against binding of [125I][MePhe7]-NKB SP to tachykinin NK-3 receptor in guinea pig cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50283255((S)-2-[(5-Oxo-pyrrolidine-2-carbonyl)-amino]-penta...)
Affinity DataIC50: 1.88E+3nMAssay Description:Concentration producing half-maximal inhibition of specific binding of [3H]senktide to Tachykinin receptor 3 in the guinea pig cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50287925(2,4-Dibenzyl-morpholin-3-one | CHEMBL441040)
Affinity DataIC50: 4.09E+3nMAssay Description:Inhibitory activity against binding of [125I][MePhe7]-NKB SP to tachykinin NK-3 receptor in guinea pig cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50283966((S)-1-Benzyl-3-(1H-indol-3-ylmethyl)-piperidin-4-o...)
Affinity DataIC50: 8.80E+3nMAssay Description:Binding affinity towards Tachykinin receptor 3 in guinea pig cerebral cortex using [3H]senktide as radioligand; Value ranges from 8.2-9.4 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50000040(CHEMBL16192 | (+)(2-Benzhydryl-1-aza-bicyclo[2.2.2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortex [125I]-BH-eledoisin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50283960(1-Benzyl-3-(1H-indol-3-ylmethyl)-piperidin-4-one |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards Tachykinin receptor 3 in guinea pig cerebral cortex using [3H]senktide as radioligand; Value ranges from 5.8-14u MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50000040(CHEMBL16192 | (+)(2-Benzhydryl-1-aza-bicyclo[2.2.2...)
Affinity DataIC50: 1.00E+4nMAssay Description:NK3 IC50 determined using [125I]bolton Hunter labeled eledoisin at NK3 receptors from guinea pig cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50051290(SR 142806 | CHEMBL299377 | SR 142801 | N-(1-{3-[1-...)
Affinity DataKi:  0.110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2011
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM85083(NKB [MePhe7])
Affinity DataKi:  0.430nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50291261(SR-14280 | SR-142801 | (S)-(+)-N-((3-[1-Benzoyl-3-...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]osanetant from guinea pig recombinant NK3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50291261(SR-14280 | SR-142801 | (S)-(+)-N-((3-[1-Benzoyl-3-...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]osanetant from guinea pig recombinant NK3 receptor A1142.58T expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM85845(N-[(S)-1-Phenylpropyl]-2-phenyl-3-(carboxymethoxy)...)
Affinity DataKi:  1.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50299468(2-(3,4-dichlorophenyl)-N-(4-fluoro-3-trifluorometh...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]osanetant from guinea pig recombinant NK3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50299468(2-(3,4-dichlorophenyl)-N-(4-fluoro-3-trifluorometh...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]osanetant from guinea pig recombinant NK3 receptor A1142.58T expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50299469(4-[4-(acetylmethyl-amino)-piperidin-1-yl]-2-(3,4-d...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]osanetant from guinea pig recombinant NK3 receptor A1142.58T expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50299469(4-[4-(acetylmethyl-amino)-piperidin-1-yl]-2-(3,4-d...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]osanetant from guinea pig recombinant NK3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
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