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TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044245(CHEMBL3314043)
Affinity DataEC50: <100nMAssay Description:Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044246(CHEMBL3314042)
Affinity DataEC50: <100nMAssay Description:Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50446283(CHEMBL3109235)
Affinity DataEC50:  9nMAssay Description:Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50445877(CHEMBL3105681)
Affinity DataEC50:  158nMAssay Description:Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105919(CHEMBL3596632)
Affinity DataEC50:  895nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105920(CHEMBL3598040)
Affinity DataEC50:  2.00E+3nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105922(CHEMBL3598041)
Affinity DataEC50:  818nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105925(CHEMBL3598044)
Affinity DataEC50:  3.11E+3nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105928(CHEMBL3598047)
Affinity DataEC50:  38nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105929(CHEMBL3598048)
Affinity DataEC50:  17nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105930(CHEMBL3598049)
Affinity DataEC50:  11nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105933(CHEMBL3598051)
Affinity DataEC50:  110nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105981(CHEMBL3598052)
Affinity DataEC50:  73nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105982(CHEMBL3598053)
Affinity DataEC50:  355nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105988(CHEMBL3598056)
Affinity DataEC50:  33nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105990(CHEMBL3598057)
Affinity DataEC50:  88nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50106014(CHEMBL3598058)
Affinity DataEC50:  128nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50106121(CHEMBL3598059)
Affinity DataEC50:  134nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105991(CHEMBL3598060)
Affinity DataEC50:  134nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105992(CHEMBL3598061)
Affinity DataEC50:  120nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105995(CHEMBL3598063)
Affinity DataEC50:  354nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105997(CHEMBL3598064)
Affinity DataEC50:  148nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50106002(CHEMBL3598070)
Affinity DataEC50:  60nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50106003(CHEMBL3598071)
Affinity DataEC50:  199nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50106007(CHEMBL3598074)
Affinity DataEC50:  201nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50106009(CHEMBL3598076)
Affinity DataEC50:  34nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153596(CHEMBL3775765)
Affinity DataEC50:  700nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153599(CHEMBL3775014)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153600(CHEMBL3774878)
Affinity DataEC50:  400nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153601(CHEMBL3775184)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153602(CHEMBL3774818)
Affinity DataEC50:  670nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153603(CHEMBL3774992)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153604(CHEMBL3775198)
Affinity DataEC50:  4.50E+3nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153605(CHEMBL3774702)
Affinity DataEC50:  2.60E+3nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153606(CHEMBL3775900)
Affinity DataEC50:  300nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153607(CHEMBL3775499)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153622(CHEMBL3775712)
Affinity DataEC50:  830nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153645(CHEMBL3774888)
Affinity DataEC50:  630nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153646(CHEMBL3775781)
Affinity DataEC50:  640nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153595(CHEMBL3775930)
Affinity DataEC50:  600nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153647(CHEMBL3774416)
Affinity DataEC50:  3.10E+3nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153648(CHEMBL3774668)
Affinity DataEC50:  450nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153649(CHEMBL3775324)
Affinity DataEC50:  1.80E+3nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153650(CHEMBL3774648)
Affinity DataEC50:  500nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153651(CHEMBL3775385)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153652(CHEMBL3774985)
Affinity DataEC50:  610nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153653(CHEMBL3775443)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153654(CHEMBL3774848)
Affinity DataEC50:  120nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153655(CHEMBL3775227)
Affinity DataEC50:  54nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50153656(CHEMBL3775304)
Affinity DataEC50:  53nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
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