Compile Data Set for Download or QSAR
Report error Found 661 of affinity data for UniProtKB/TrEMBL: P52895
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330426BDBM50330426(5-Fluoro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330431BDBM50330431(4'-Butyl-5-chloro-4-hydroxybiphenyl-3-carboxylic a...)
Affinity DataKi:  14nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427620BDBM50427620(CHEMBL2323507 | US9346803, 2)
Affinity DataIC50: 14.5nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330428BDBM50330428(5-Chloro-4-hydroxy-3'-methylbiphenyl-3-carboxylic ...)
Affinity DataKi:  17nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330427BDBM50330427(5-Chloro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  21nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330424BDBM50330424(5-Chloro-4-hydroxy-4'-(trifluoromethoxy)biphenyl-3...)
Affinity DataKi:  26nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330432BDBM50330432(5-Chloro-4-hydroxy-4'-isobutylbiphenyl-3-carboxyli...)
Affinity DataKi:  29nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427627BDBM50427627(CHEMBL2323474 | US9346803, Table 2, Compound 9: 2-...)
Affinity DataIC50: 35.7nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427628BDBM50427628(CHEMBL2323472 | US9346803, Table 2, Compound 8: 2-...)
Affinity DataIC50: 40.7nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427622BDBM50427622(CHEMBL2323508 | US9346803, Table 2, Compound 10: 3...)
Affinity DataIC50: 49.6nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427621BDBM50427621(CHEMBL2323490 | US9346803, 1)
Affinity DataIC50: 50.1nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427624BDBM50427624(CHEMBL2323522 | US9346803, Table 2, Compound 11: 9...)
Affinity DataIC50: 53.5nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427629BDBM50427629(CHEMBL179587 | US9346803, Table 2, Compound 7: 2-[...)
Affinity DataIC50: 54.5nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427625BDBM50427625(CHEMBL178687 | US9346803, Table 2, Compound 6: 3-[...)
Affinity DataIC50: 57nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330429BDBM50330429(5-Chloro-4-hydroxy-4'-methylbiphenyl-3-carboxylic ...)
Affinity DataKi:  63nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26269BDBM26269(3,5-dichloro-2-hydroxybenzoic acid | CHEMBL449129 ...)
Affinity DataKi:  70nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26269BDBM26269(3,5-dichloro-2-hydroxybenzoic acid | CHEMBL449129 ...)
Affinity DataKi:  70nM ΔG°:  -40.8kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427626BDBM50427626(CHEMBL2323481 | US9346803, Table 2, Compound 5: 2-...)
Affinity DataIC50: 81nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249792BDBM50249792(3,5-Dibromosalicylic acid | CHEMBL447448)
Affinity DataKi:  82nMAssay Description:Inhibition of human recombinant type 3 3-alpha-HSD expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219490BDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataKi:  87nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219490BDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataKi:  87nMAssay Description:Inhibition of human recombinant type 3 3-alpha-HSD expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427619BDBM50427619(CHEMBL2323511 | US9346803, 3)
Affinity DataIC50: 93nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293598BDBM50293598(2'-des-methyl indomethacin | CHEMBL503179 | US9346...)
Affinity DataIC50: 100nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623961BDBM50623961(CHEMBL194686)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124577BDBM50124577(CHEMBL3623738)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant AKR1C2 (unknown origin) using S-tetralol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385711BDBM50385711(CHEMBL22815)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624016BDBM50624016(CHEMBL5436838)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330425BDBM50330425(3-chloro-2-hydroxy-5-(phenylethynyl)benzoic acid |...)
Affinity DataKi:  168nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385765BDBM50385765(CHEMBL2043318)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385761BDBM50385761(CHEMBL2043313)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623977BDBM50623977(CHEMBL5401700)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134036BDBM50134036(cid_4044 | mefanamic acid | CHEMBL686 | CI-473 | C...)
Affinity DataKi:  220nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385722BDBM50385722(CHEMBL2043310)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624003BDBM50624003(CHEMBL5398882)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623978BDBM50623978(CHEMBL5419252)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624008BDBM50624008(CHEMBL5405863)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623963BDBM50623963(CHEMBL5426283)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124575BDBM50124575(CHEMBL3623735)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant AKR1C2 (unknown origin) using S-tetralol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385766BDBM50385766(CHEMBL2043319)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35901BDBM35901(cid_201986 | flufenamic acid analogue, 28)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623995BDBM50623995(CHEMBL5422601)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385762BDBM50385762(CHEMBL2043314)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172470BDBM50172470(2-(2-Fluoro-4'-trifluoromethyl-biphenyl-4-yl)-prop...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385767BDBM50385767(CHEMBL2043320)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623972BDBM50623972(CHEMBL5419326)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623971BDBM50623971(CHEMBL5406588)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623989BDBM50623989(CHEMBL5439918)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624000BDBM50624000(CHEMBL5414784)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624010BDBM50624010(CHEMBL5396002)
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17636BDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50: 370nMAssay Description:Inhibition of AKR1C2 by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
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