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Report error Found 2517 of affinity data for UniProtKB/TrEMBL: P53634
TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM729472(US20250101011, Compound D67)
Affinity DataIC50: 0.180nMAssay Description:Experimental Methods1) Preparation and handling of compounds: Accurately weigh the compound and dissolve it in 10 mL of DMSO to prepare a 10-mL of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM729472(US20250101011, Compound D67)
Affinity DataIC50: 0.180nMAssay Description:Experimental Methods1) Preparation and handling of compounds: Accurately weigh the compound and dissolve it in 10 mL of DMSO to prepare a 10-mL of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201017(US9540373, 6 | US9879026, Example 6 | USRE47636, E...)
Affinity DataIC50: 0.200nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201017(US9540373, 6 | US9879026, Example 6 | USRE47636, E...)
Affinity DataIC50: 0.200nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201017(US9540373, 6 | US9879026, Example 6 | USRE47636, E...)
Affinity DataIC50: 0.200nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM50195247(CHEMBL3936580)
Affinity DataIC50: 0.251nMAssay Description:Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201014(US9540373, 3 | US9879026, Example 3 | USRE47636, E...)
Affinity DataIC50: 0.300nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201014(US9540373, 3 | US9879026, Example 3 | USRE47636, E...)
Affinity DataIC50: 0.300nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM50310682((S)-2-amino-N-((S)-1-cyano-2-(5-phenylthiophen-2-y...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM633586(N ((S)-1-cyano-2-(3-fluoro-4′-(pentafluoro-1...)
Affinity DataIC50: 0.300nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201014(US9540373, 3 | US9879026, Example 3 | USRE47636, E...)
Affinity DataIC50: 0.300nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM729479(US20250101011, Compound D92)
Affinity DataIC50: 0.320nMAssay Description:Experimental Methods1) Preparation and handling of compounds: Accurately weigh the compound and dissolve it in 10 mL of DMSO to prepare a 10-mL of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM50502619(CHEMBL4561264)
Affinity DataIC50: 0.398nMAssay Description:Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201015(US9540373, 4 | US9879026, Example 4 | USRE47636, E...)
Affinity DataIC50: 0.400nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201015(US9540373, 4 | US9879026, Example 4 | USRE47636, E...)
Affinity DataIC50: 0.400nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201015(US9540373, 4 | US9879026, Example 4 | USRE47636, E...)
Affinity DataIC50: 0.400nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM729466(US20250101011, Compound D46)
Affinity DataIC50: 0.450nMAssay Description:Experimental Methods1) Preparation and handling of compounds: Accurately weigh the compound and dissolve it in 10 mL of DMSO to prepare a 10-mL of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201018(US9540373, 7 | US9879026, Example 7 | USRE47636, E...)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201026(US9540373, 15 | US9879026, Example 15 | USRE47636,...)
Affinity DataIC50: 0.5nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201027(US9540373, 16 | US9879026, Example 16 | USRE47636,...)
Affinity DataIC50: 0.5nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201026(US9540373, 15 | US9879026, Example 15 | USRE47636,...)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201018(US9540373, 7 | US9879026, Example 7 | USRE47636, E...)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201023(US9540373, 12 | US9879026, Example 12 | USRE47636,...)
Affinity DataIC50: 0.5nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201023(US9540373, 12 | US9879026, Example 12 | USRE47636,...)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201018(US9540373, 7 | US9879026, Example 7 | USRE47636, E...)
Affinity DataIC50: 0.5nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201020(US9540373, 9 | US9879026, Example 9 | USRE47636, E...)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201020(US9540373, 9 | US9879026, Example 9 | USRE47636, E...)
Affinity DataIC50: 0.5nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201027(US9540373, 16 | US9879026, Example 16 | USRE47636,...)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM633583((S) N ((S)-1-cyano-2-(2-fluoro-4-(3-(methyl-d3)-2-...)
Affinity DataIC50: 0.5nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201026(US9540373, 15 | US9879026, Example 15 | USRE47636,...)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201023(US9540373, 12 | US9879026, Example 12 | USRE47636,...)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201020(US9540373, 9 | US9879026, Example 9 | USRE47636, E...)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201027(US9540373, 16 | US9879026, Example 16 | USRE47636,...)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM729473(US20250101011, Compound D70)
Affinity DataIC50: 0.580nMAssay Description:Experimental Methods1) Preparation and handling of compounds: Accurately weigh the compound and dissolve it in 10 mL of DMSO to prepare a 10-mL of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM150482(US8987249, 156 | US9713606, 156 | US10238633, Exam...)
Affinity DataIC50: 0.600nMAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201016(US9540373, 5 | US9879026, Example 5 | USRE47636, E...)
Affinity DataIC50: 0.600nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201013(US9540373, 2 | US9879026, Example 2 | USRE47636, E...)
Affinity DataIC50: 0.600nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM150482(US8987249, 156 | US9713606, 156 | US10238633, Exam...)
Affinity DataIC50: 0.600nMpH: 6.0 T: 2°CAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 6007270). The substrate Gly-Arg-AMC was from Biotrend (Prod....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201021(US9540373, 10 | US9879026, Example 10 | USRE47636,...)
Affinity DataIC50: 0.600nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201024(US9540373, 13 | US9879026, Example 13 | USRE47636,...)
Affinity DataIC50: 0.600nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201024(US9540373, 13 | US9879026, Example 13 | USRE47636,...)
Affinity DataIC50: 0.600nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201016(US9540373, 5 | US9879026, Example 5 | USRE47636, E...)
Affinity DataIC50: 0.600nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM150482(US8987249, 156 | US9713606, 156 | US10238633, Exam...)
Affinity DataIC50: 0.600nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201021(US9540373, 10 | US9879026, Example 10 | USRE47636,...)
Affinity DataIC50: 0.600nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201013(US9540373, 2 | US9879026, Example 2 | USRE47636, E...)
Affinity DataIC50: 0.600nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201013(US9540373, 2 | US9879026, Example 2 | USRE47636, E...)
Affinity DataIC50: 0.600nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201016(US9540373, 5 | US9879026, Example 5 | USRE47636, E...)
Affinity DataIC50: 0.600nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201024(US9540373, 13 | US9879026, Example 13 | USRE47636,...)
Affinity DataIC50: 0.600nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM201021(US9540373, 10 | US9879026, Example 10 | USRE47636,...)
Affinity DataIC50: 0.600nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
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TargetDipeptidyl peptidase 1(Human)
Shanghai Yidian Pharmaceutical Technology Development Co.

US Patent
LigandPNGBDBM633575((S) N ((S)-1-cyano-2-(2-fluoro-4-(3-methyl-2-oxo-2...)
Affinity DataIC50: 0.640nMAssay Description:Experimental Methods:1× activation buffer: 5 mM DTT 0.01% (V/V) Triton X-100 (preparation for current use);1× assay buffer: 50 mM NaCl 5 mM DTT 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
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