Compile Data Set for Download or QSAR
Report error Found 104 of affinity data for UniProtKB/TrEMBL: P58406
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50514105(CHEMBL4441731)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at mouse H3R expressed on HEK293T cells assessed as inhibition of forskolin-induced CRE-driven luciferase activity co-incubated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50352081(CHEMBL1824230)
Affinity DataKi:  0.280nMAssay Description:Displacement of [125I]Iodoproxyfan from mouse brain cortex histamine H3 receptor after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50352095(CHEMBL1824235)
Affinity DataKi:  0.330nMAssay Description:Displacement of [125I]Iodoproxyfan from mouse brain cortex histamine H3 receptor after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50352099(CHEMBL1824231)
Affinity DataKi:  0.520nMAssay Description:Displacement of [125I]Iodoproxyfan from mouse brain cortex histamine H3 receptor after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM22541(VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...)
Affinity DataKi:  0.600nMAssay Description:Displacement of 3-([1,1,1-3H]methyl)-2-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone from mouse histamine H3 receptor expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM22541(VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity against mouse histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50514105(CHEMBL4441731)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]NAMH from mouse H3R expressed in HEK293T cells incubated for 2 hrs by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50352101(CHEMBL1824236)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]Iodoproxyfan from mouse brain cortex histamine H3 receptor after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50352096(CHEMBL1824234)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]Iodoproxyfan from mouse brain cortex histamine H3 receptor after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50352086(CHEMBL1824245)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]Iodoproxyfan from mouse brain cortex histamine H3 receptor after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50352097(CHEMBL1824233)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]Iodoproxyfan from mouse brain cortex histamine H3 receptor after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50352090(CHEMBL1824241)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]-iodoproxyfan from histamine H3 receptor in mouse brain cortex after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50352090(CHEMBL1824241)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]Iodoproxyfan from mouse brain cortex histamine H3 receptor after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM22541(VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...)
Affinity DataEC50:  1.70nMAssay Description:Inverse agonist activity at mouse histamine H3 receptor overexpressed in HEK293 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50264895(5-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-2...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to mouse histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50441511(CHEMBL2436620)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM22911(2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide |...)
Affinity DataKi:  2nMAssay Description:Displacement of 3-([1,1,1-3H]methyl)-2-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone from mouse histamine H3 receptor expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50441503(CHEMBL2436628)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50352084(CHEMBL1824247)
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]Iodoproxyfan from mouse brain cortex histamine H3 receptor after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50352092(CHEMBL1824239)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]Iodoproxyfan from mouse brain cortex histamine H3 receptor after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50246289(CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...)
Affinity DataKi:  2.40nMAssay Description:Displacement of 3-([1,1,1-3H]methyl)-2-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone from mouse histamine H3 receptor expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50383442(CHEMBL2031602)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50433200(CHEMBL2375594)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]-iodoproxyfan from histamine H3 receptor in mouse brain cortex after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50246289(CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...)
Affinity DataKd:  2.60nMAssay Description:Binding affinity to mouse histamine H3 receptor overexpressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50383459(CHEMBL2031619)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50441505(CHEMBL2436626)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50441509(CHEMBL2436622)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50441506(CHEMBL2436625)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50246289(CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...)
Affinity DataKd:  3.10nMAssay Description:Binding affinity to histamine H3 receptor in wild type mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50274235(3-(4-[(1-Cyclobutyl-4-piperidinyl)oxy]phenyl)-2-me...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse recombinant histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50274200(3-(4-[(1-Cyclobutyl-4-piperidinyl)oxy]phenyl)-2,5-...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse recombinant histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50386346(CHEMBL2048594)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from mouse recombinant histamine H3 receptor after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50441514(CHEMBL2436633)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50441504(CHEMBL2436627)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50386346(CHEMBL2048594)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from mouse recombinant histamine H3 receptor after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50441502(CHEMBL2436629)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50441507(CHEMBL2436624)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50433199(CHEMBL2375595)
Affinity DataKi:  4.30nMAssay Description:Displacement of [125I]-iodoproxyfan from histamine H3 receptor in mouse brain cortex after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKi:  4.80nMAssay Description:Displacement of 3-([1,1,1-3H]methyl)-2-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone from mouse histamine H3 receptor expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50386351(CHEMBL2048589)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from mouse recombinant histamine H3 receptor after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50296171(1-{3-[4-((2S,3S)-8-Methoxy-3-methyl-4,4-dioxo-3,4-...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]R-alpha-methylhistamine from mouse histamine H3 receptor by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50433198(CHEMBL2375588)
Affinity DataKi:  6.30nMAssay Description:Displacement of [125I]-iodoproxyfan from histamine H3 receptor in mouse brain cortex after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50433194(CHEMBL2375587)
Affinity DataKi:  6.90nMAssay Description:Displacement of [125I]-iodoproxyfan from histamine H3 receptor in mouse brain cortex after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50386364(CHEMBL2048592)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from mouse recombinant histamine H3 receptor after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50441501(CHEMBL2436630)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50441512(CHEMBL2436617)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50383445(CHEMBL2031605)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50433197(CHEMBL2375597)
Affinity DataKi:  7.60nMAssay Description:Displacement of [125I]-iodoproxyfan from histamine H3 receptor in mouse brain cortex after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50274692(3-(4-[(1-Cyclobutyl-4-piperidinyl)oxy]phenyl)-5-fl...)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse recombinant histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50246289(CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...)
Affinity DataEC50:  9.60nMAssay Description:Inverse agonist activity at mouse histamine H3 receptor overexpressed in HEK293 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 104 total ) | Next | Last >>
Jump to: