Compile Data Set for Download or QSAR
Report error Found 13 of affinity data for UniProtKB/TrEMBL: P62617
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM31907(5-oxopentanoic acid, 4)
Affinity DatapH: 7.0 T: 2°CAssay Description:An SPR assay was used to determine the binding affinities of compounds. Experiments were performed on a Biacore 3000 (Biacore, Uppsala, Sweden) instr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM31909(Cytidine 2,3-cyclic phosphate, 6)
Affinity DataKd:  2.05E+7nMpH: 7.0 T: 2°CAssay Description:An SPR assay was used to determine the binding affinities of compounds. Experiments were performed on a Biacore 3000 (Biacore, Uppsala, Sweden) instr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM31910(Cyclic CMP, 7)
Affinity DataKd:  9.00E+5nMpH: 7.0 T: 2°CAssay Description:An SPR assay was used to determine the binding affinities of compounds. Experiments were performed on a Biacore 3000 (Biacore, Uppsala, Sweden) instr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM31911(2-[(2,6-diaminopyrimidin-4-yl)sulfanyl]acetamide, ...)
Affinity DatapH: 7.0 T: 2°CAssay Description:An SPR assay was used to determine the binding affinities of compounds. Experiments were performed on a Biacore 3000 (Biacore, Uppsala, Sweden) instr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM31912(4-(5-amino-1,3,4-oxadiazol-2-yl)-1,2,5-oxadiazol-3...)
Affinity DatapH: 7.0 T: 2°CAssay Description:An SPR assay was used to determine the binding affinities of compounds. Experiments were performed on a Biacore 3000 (Biacore, Uppsala, Sweden) instr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM31913(cytidylic acid | 1-beta-D-arabinofuranosylcytosine...)
Affinity DataKd:  1.89E+7nMpH: 7.0 T: 2°CAssay Description:An SPR assay was used to determine the binding affinities of compounds. Experiments were performed on a Biacore 3000 (Biacore, Uppsala, Sweden) instr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM31914(FLUC | 4-amino-1-[(2R,3R,4S,5R)-3, 4-dihydroxy-5-(...)
Affinity DataKd:  2.02E+6nMpH: 7.0 T: 2°CAssay Description:An SPR assay was used to determine the binding affinities of compounds. Experiments were performed on a Biacore 3000 (Biacore, Uppsala, Sweden) instr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM31915(HPMPC | Vistide | CDV | Cidofovir | US10071110, Co...)
Affinity DataKd:  4.00E+7nMpH: 7.0 T: 2°CAssay Description:An SPR assay was used to determine the binding affinities of compounds. Experiments were performed on a Biacore 3000 (Biacore, Uppsala, Sweden) instr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM31916(Tryptophanhydroxamate, 13)
Affinity DataKd:  1.92E+3nMpH: 7.0 T: 2°CAssay Description:An SPR assay was used to determine the binding affinities of compounds. Experiments were performed on a Biacore 3000 (Biacore, Uppsala, Sweden) instr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM31916(Tryptophanhydroxamate, 13)
Affinity DataKd:  2.20E+4nMAssay Description:Binding affinity to Escherichia coli IspF at pH 7.4 measured by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM50496771(CHEMBL3220831)
Affinity DataIC50: 3.43E+5nMAssay Description:Inhibition of Escherichia coli IspF-MEP complex by HPLC based cAMP formation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM50194153(5'-CDP | Cytidine 5'-pyrophosphate | CDP | Cytidin...)
Affinity DataIC50: 7.68E+5nMAssay Description:Inhibition of Escherichia coli IspF by HPLC based cAMP formation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
University of Dundee

LigandPNGBDBM50496771(CHEMBL3220831)
Affinity DataIC50: 7.97E+5nMAssay Description:Inhibition of Escherichia coli IspF by HPLC based cAMP formation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed