Compile Data Set for Download or QSAR
Report error Found 17 of affinity data for UniProtKB/TrEMBL: P97772
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50333367(6-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-tria...)
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to mouse mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273899(tert-Butyl-4-[1-(2-fuluoropyridine-3-yl)-5-methyl-...)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273942(CHEMBL502882 | CHEMBL1645350 | 4-[1-(2-Fuluoropyri...)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273941(iso-Propyl-4-[1-(2-fuluoropyridine-3-yl)-5-methyl-...)
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273898(tert-Butyl-4-[1-(2-fuluoropyridine-3-yl)-1H-1,2,3-...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273829(tert-Butyl-4-[1-(2-fluorophenyl)-1H-1,2,3-triazol-...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273828(tert-Butyl-4-(1-phenyl-1H-1,2,3-triazole-4-yl)-3,6...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273863(tert-Butyl-4-[1-(4-fuluorophenyl)-1H-1,2,3-triazol...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273830(tert-Butyl-4-[1-(3-fuluorophenyl)-1H-1,2,3-triazol...)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273864(tert-Butyl-4-[1-(2-methylphenyl)-1H-1,2,3-triazol-...)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273895(tert-Butyl-4-[1-pyridin-2-yl-1H-1,2,3-triazol-4-yl...)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273867(1-(3,3-Dimethylbutanolyl)-4-[1-(2-fluorophenyl)-1H...)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273896(tert-Butyl-4-[1-pyridin-3-yl-1 H-1,2,3-triazol-4-y...)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273940(iso-Propyl-4-[1-(2-fuluoropyridine-3-yl)-1H-1,2,3-...)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273866(N-(tert-Butyl)-4-[1-(2-fluorophenyl)-1H-1,2,3-tria...)
Affinity DataIC50: 290nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273897(tert-Butyl-4-[1-pyridin-4-yl-1 H-1,2,3-triazol-4-y...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273865(tert-Butyl-4-[1-(2-methoxylphenyl)-1H-1,2,3-triazo...)
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed