Compile Data Set for Download or QSAR
Report error Found 11 of affinity data for UniProtKB/TrEMBL: Q60641
TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28542(propan-2-yl 3-[(3,4-difluorophenyl)carbonyl]-1,1-d...)
Affinity DataEC50:  152nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306734(isopropyl 3-(3,4-difluorobenzoyl)-9-fluoro-1,1-dim...)
Affinity DataEC50:  112nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306735(1-methylethyl 8-fluoro-1,1-dimethyl-3-{[4-(3-morph...)
Affinity DataEC50:  52nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306744(Isopropyl 8-Fluoro-1,1-dimethyl-3-[4-(2-morpholin-...)
Affinity DataEC50:  188nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306714(Isopropyl 1,1-Dimethyl-3-[4-(3-morpholin-4-ylpropo...)
Affinity DataEC50:  108nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306718(Isopropyl 1,1-Dimethyl-3-[4-(2-morpholin-4-ylethox...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21674(Chenodeoxycholic Acid | CDCA | (4R)-4-[(1S,2S,5R,7...)
Affinity DataEC50:  1.68E+4nMAssay Description:Agonist activity at mouse FXR expressed in HEK293 cells co-expressing mouse RXRalpha and ECRE-luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50359364(CHEMBL1929242)
Affinity DataEC50:  3.15E+3nMAssay Description:Agonist activity at mouse FXR expressed in HEK293 cells co-expressing mouse RXRalpha and ECRE-luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50359365(CHEMBL1929243)
Affinity DataEC50:  6.17E+3nMAssay Description:Agonist activity at mouse FXR expressed in HEK293 cells co-expressing mouse RXRalpha and ECRE-luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50572221(CHEMBL4862974)
Affinity DataEC50:  320nMAssay Description:Agonist activity at mouse LBD fused FXR in HEK293 cells incubated for 30 min by envision plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50600733(CHEMBL5182534)
Affinity DataEC50:  14nMAssay Description:Agonist activity at mouse LBD fused FXR in HEK293 cells incubated for 30 min by envision plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed