Compile Data Set for Download or QSAR
Report error Found 1196 of affinity data for UniProtKB/TrEMBL: Q96EB6
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29041(cambinol analog, 6a)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29043(cambinol analog, 6c)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29044(cambinol analog, 6d)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29048(cambinol analog, 6iv)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29049(cambinol analog, 6v)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29050(cambinol analog, 6vi)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29051(cambinol analog, 6vii)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29052(cambinol analog, 6viii)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29053(cambinol analog, 6ix)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29057(cambinol analog, 6f)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29058(cambinol analog, 6g)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29059(cambinol analog, 6h)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29060(cambinol analog, 6j)
Affinity DatapH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50228364(3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...)
Affinity DataKd:  1.62E+4nMAssay Description:Binding affinity to SIRT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50396046(CHEMBL482552)
Affinity DataEC50:  400nMAssay Description:Activation of SIRT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50396047(CHEMBL482551)
Affinity DataEC50:  300nMAssay Description:Activation of SIRT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50396048(CHEMBL483942)
Affinity DataEC50:  4.40E+3nMAssay Description:Activation of SIRT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50396049(CHEMBL473881)
Affinity DataEC50:  900nMAssay Description:Activation of SIRT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50396050(CHEMBL470836)
Affinity DataEC50:  2.50E+4nMAssay Description:Activation of SIRT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50396051(CHEMBL470835)
Affinity DataEC50:  6.00E+3nMAssay Description:Activation of SIRT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50193048(CHEMBL3934191)
Affinity DataEC50: <1.00E+3nMAssay Description:Activation of recombinant human SIRT1 assessed as increase in deacetylation of Fluor de Lys-SIRT1-specific substrate after 2 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50193072(CHEMBL3906219)
Affinity DataEC50: <1.00E+3nMAssay Description:Activation of recombinant human SIRT1 assessed as increase in deacetylation of Fluor de Lys-SIRT1-specific substrate after 2 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50193077(CHEMBL3941013)
Affinity DataEC50: <1.00E+3nMAssay Description:Activation of recombinant human SIRT1 assessed as increase in deacetylation of Fluor de Lys-SIRT1-specific substrate after 2 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50425824(CHEMBL2312289)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to C-terminally His-tagged SIRT1 catalytic domain (241 to 516 amino acid residues plus EGHHHHHH) (unknown origin) expressed in bacul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428977(CHEMBL524124)
Affinity DataEC50:  6.90E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428978(CHEMBL522606)
Affinity DataEC50:  610nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428979(CHEMBL522622)
Affinity DataEC50:  4.50E+4nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428980(CHEMBL491082)
Affinity DataEC50:  680nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50228363(N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...)
Affinity DataEC50:  160nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428981(CHEMBL490091)
Affinity DataEC50:  990nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428982(CHEMBL2333649)
Affinity DataEC50:  1.70E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428983(CHEMBL523275)
Affinity DataEC50:  2.50E+4nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428984(CHEMBL489891)
Affinity DataEC50:  3.10E+4nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428985(CHEMBL490880)
Affinity DataEC50:  3.70E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50228364(3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...)
Affinity DataEC50:  1.80E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428986(CHEMBL489692)
Affinity DataEC50:  1.40E+4nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428987(CHEMBL523969)
Affinity DataEC50:  1.30E+5nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428988(CHEMBL2333666)
Affinity DataEC50:  1.80E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428989(CHEMBL2333665)
Affinity DataEC50:  2.60E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428990(CHEMBL2333664)
Affinity DataEC50:  900nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428991(CHEMBL2333663)
Affinity DataEC50:  4.40E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428992(CHEMBL2333662)
Affinity DataEC50:  2.30E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428993(CHEMBL2333661)
Affinity DataEC50:  8.70E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM31967(carbohydrazide derivative, 5j)
Affinity DataEC50:  2.70E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428994(CHEMBL2333659)
Affinity DataEC50:  5.52E+4nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428995(CHEMBL2333658)
Affinity DataEC50:  2.05E+4nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428996(CHEMBL2333657)
Affinity DataEC50:  9.60E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428997(CHEMBL2333656)
Affinity DataEC50:  2.30E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428998(CHEMBL2333655)
Affinity DataEC50:  2.00E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM50428999(CHEMBL2333654)
Affinity DataEC50:  1.60E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
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