Compile Data Set for Download or QSAR
Report error Found 62 of affinity data for UniProtKB/TrEMBL: Q9I194
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113784BDBM113784(2-(4-Chlorophenyl)-2-(6-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 10nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113783BDBM113783(2-(4-Chlorophenyl)-2-(3-chloropyridin-2-yl) aceton...)
Affinity DataIC50: 10nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113799BDBM113799(2-(4-Chloro-2-fluorophenyl)-2-(5-(trifluoromethyl)...)
Affinity DataIC50: 10nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113772BDBM113772(2-(4-Fluorophenyl)-2-(6-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 20nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257750BDBM50257750(SMER28 (2) | cid_1560402 | CHEMBL494325 | N-allyl-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Pseudomonas aeruginosa ATCC 15692 pvdQ incubated for 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAcyl-homoserine lactone acylase PvdQ(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 113770BDBM113770(NS2028 (1))
Affinity DataIC50: 20nMAssay Description:Inhibition of Pseudomonas aeruginosa ATCC 15692 pvdQ incubated for 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113771BDBM113771(2‐(4‐chlorophenyl)‐2‐(6...)
Affinity DataIC50: 40nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113781BDBM113781(2-(4-Chloro-2-fluorophenyl)-2-(6-chloropyridin-2-y...)
Affinity DataIC50: 60nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113777BDBM113777(2-(6-Chloropyridin-2-yl)-2-(4-fluorophenyl)acetoni...)
Affinity DataIC50: 70nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113798BDBM113798(6-((4-Chloro-2-fluorophenyl)(cyano)methyl) picolin...)
Affinity DataIC50: 110nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113793BDBM113793(6-(Cyano(4-fluorophenyl)methyl)picolinonitrile (25...)
Affinity DataIC50: 130nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113794BDBM113794(6-(Cyano(4-fluorophenyl)methyl)-3-methylpicolinoni...)
Affinity DataIC50: 130nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113782BDBM113782(2-(4-Chlorophenyl)-2-(5-chloropyridin-2-yl) aceton...)
Affinity DataIC50: 130nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113797BDBM113797(2-(4-(Trifluoromethyl)phenyl)-2-(6-(trifluoromethy...)
Affinity DataIC50: 140nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113790BDBM113790(6-((4-Chlorophenyl)(cyano)methyl)-3-methyl picolin...)
Affinity DataIC50: 180nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113785BDBM113785(6-((4-Chlorophenyl)(cyano)methyl)picolinonitrile (...)
Affinity DataIC50: 180nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 113772BDBM113772(2-(4-Fluorophenyl)-2-(6-(trifluoromethyl)pyridin-2...)
Affinity DataKi:  190nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa ATCC 15692 pvdQMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113803BDBM113803(2-(3-Chloropyridin-2-yl)-2-(2,4-dichlorophenyl) ac...)
Affinity DataIC50: 210nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113787BDBM113787(2-(4-Chlorophenyl)-2-(5-methylpyridin-2-yl) aceton...)
Affinity DataIC50: 250nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113786BDBM113786(2-(4-Chlorophenyl)-2-(6-methylpyridin-2-yl)acetoni...)
Affinity DataIC50: 250nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113780BDBM113780(2-(6-Chloropyridin-2-yl)-2-(2,4-dichlorophenyl) ac...)
Affinity DataIC50: 250nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113813BDBM113813(2-(4-Chlorophenyl)-2-(pyrrolidin-1-yl)acetonitrile...)
Affinity DataIC50: 260nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113792BDBM113792(2-(4-Chlorophenyl)-2-(pyridin-2-yl)acetonitrile (2...)
Affinity DataIC50: 270nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113807BDBM113807(2-(4-Chlorophenyl)-4-methylpentanenitrile (39))
Affinity DataIC50: 290nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113801BDBM113801(6-(Cyano(2,4-dichlorophenyl)methyl)picolinonitrile...)
Affinity DataIC50: 290nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113815BDBM113815(2-(4-Fluorophenyl)-4-methoxybutanenitrile (47))
Affinity DataIC50: 290nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113775BDBM113775(2‐(6‐chloropyridin‐2‐yl)&#...)
Affinity DataIC50: 300nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113814BDBM113814(2-(4-Fluorophenyl)hexanenitrile (46))
Affinity DataIC50: 320nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113818BDBM113818(2-(5-Fluoropyridin-2-yl)hexanenitrile (50))
Affinity DataIC50: 370nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113778BDBM113778(2-(6-Chloropyridin-2-yl)-2-(4-(trifluoromethyl) ph...)
Affinity DataIC50: 390nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113776BDBM113776(2‐(6‐chloropyridin‐2‐yl)&#...)
Affinity DataIC50: 400nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113808BDBM113808(2-(4-Chlorophenyl)-3-cyclopropylpropanenitrile (40...)
Affinity DataIC50: 540nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113789BDBM113789(2-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(4-...)
Affinity DataIC50: 620nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113800BDBM113800(2-(4-Chloro-2-fluorophenyl)-2-(6-chloro-5-(trifluo...)
Affinity DataIC50: 630nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113795BDBM113795(2-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(4-...)
Affinity DataIC50: 740nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113804BDBM113804(2-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(2,...)
Affinity DataIC50: 970nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113822BDBM113822(2-(4-Chlorophenyl)-2-(5-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 1.10E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113806BDBM113806(2-(4-Chlorophenyl)hexanenitrile (38))
Affinity DataIC50: 1.40E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113779BDBM113779(2-(6-Chloropyridin-2-yl)-2-(2-(trifluoromethoxy)-p...)
Affinity DataIC50: 1.70E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113802BDBM113802(6-(Cyano(2,4-dichlorophenyl)methyl)nicotinonitrile...)
Affinity DataIC50: 1.80E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 113772BDBM113772(2-(4-Fluorophenyl)-2-(6-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa ATCC 15692 pvdQ measured after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113796BDBM113796(2-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(4-...)
Affinity DataIC50: 2.30E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113788BDBM113788(2-(4-Chlorophenyl)-2-(5-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 2.40E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113791BDBM113791(6-((4-Chlorophenyl)(cyano)methyl)nicotinonitrile (...)
Affinity DataIC50: 2.50E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113820BDBM113820(2-Chloro-6-((4-chlorophenyl)(1H-tetrazol-5-yl)-met...)
Affinity DataIC50: 3.40E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113817BDBM113817(2-(5-Chloropyridin-2-yl)hexanenitrile (49))
Affinity DataIC50: 3.80E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113810BDBM113810(2-(4-Chlorophenyl)-4-(2-methoxyethoxy)butanenitril...)
Affinity DataIC50: 4.70E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113809BDBM113809(2-(4-Chlorophenyl)-4-methoxybutanenitrile (41))
Affinity DataIC50: 4.80E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113805BDBM113805(2-(4-Chlorophenyl)pentanenitrile (37))
Affinity DataIC50: 5.90E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandChemical structure of BindingDB Monomer ID 113821BDBM113821(5-(1-(4-Chlorophenyl)pentyl)-1H-tetrazole (53))
Affinity DataIC50: 6.70E+3nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
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