Compile Data Set for Download or QSAR
Report error Found 494 of affinity data for UniProtKB/TrEMBL: Q9NTG7
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50428988(CHEMBL2333666)
Affinity DataEC50:  2.86E+4nMAssay Description:Activation of N-terminal His6-tagged SIRT3 (118 to 399 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM23926(5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol...)
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT3 by mass spectrometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50376978(SRT-2183 | CHEMBL403308)
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT3 by mass spectrometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50228363(N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...)
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT3 by mass spectrometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50228364(3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...)
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT3 by mass spectrometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577527(CHEMBL4865045)
Affinity DataEC50:  5.79E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577528(CHEMBL4861710)
Affinity DataEC50:  1.90E+4nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577529(CHEMBL4867991)
Affinity DataEC50:  860nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577530(CHEMBL4872871)
Affinity DataEC50:  2.68E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577531(CHEMBL4873596)
Affinity DataEC50:  1.23E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577532(CHEMBL4857450)
Affinity DataEC50:  3.07E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577533(CHEMBL4862594)
Affinity DataEC50:  1.29E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577534(CHEMBL4877287)
Affinity DataEC50:  1.74E+4nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577535(CHEMBL4864400)
Affinity DataEC50:  1.67E+4nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577536(CHEMBL4873538)
Affinity DataEC50:  690nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577537(CHEMBL4874389)
Affinity DataEC50:  2.38E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577538(CHEMBL4876268)
Affinity DataEC50:  3.02E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577539(CHEMBL4874747)
Affinity DataEC50:  7.01E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18957((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)
Affinity DataEC50:  3.25E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577540(CHEMBL429288)
Affinity DataEC50:  4.69E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577541(CHEMBL396734)
Affinity DataEC50:  2.88E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577542(CHEMBL4868328)
Affinity DataEC50:  210nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577543(CHEMBL4874517)
Affinity DataEC50:  1.65E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577544(CHEMBL4873699)
Affinity DataEC50:  780nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577545(CHEMBL4870147)
Affinity DataEC50:  3.46E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577546(CHEMBL4860837)
Affinity DataEC50:  1.06E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577547(CHEMBL4872584)
Affinity DataEC50:  4.15E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577548(CHEMBL4869237)
Affinity DataEC50:  2.37E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577549(CHEMBL4852958)
Affinity DataEC50:  1.07E+4nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577550(CHEMBL243473)
Affinity DataEC50:  1.62E+4nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577551(CHEMBL4871502)
Affinity DataEC50:  810nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577552(CHEMBL4856205)
Affinity DataEC50:  5.41E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577553(CHEMBL4869431)
Affinity DataEC50:  3.50E+3nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM23926(5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol...)
Affinity DataEC50:  5.52E+4nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-diallylbiphenyl-2,4'-diol | CHEMBL16901 | cid...)
Affinity DataEC50:  170nMAssay Description:Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50576688(CHEMBL4873020)
Affinity DataKd:  3.92E+5nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT3 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50576689(CHEMBL4872893)
Affinity DataKd:  4.88E+5nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT3 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50576690(CHEMBL4873772)
Affinity DataKd:  2.97E+5nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT3 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50591386(CHEMBL5171187)
Affinity DataEC50:  1.00E+5nMAssay Description:Activation of N-terminal his-tagged human SIRT3 (114 to 380 residues) expressed in Escherichia coli in presence of NAD+ by Mass spectrometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50591387(CHEMBL5171546)
Affinity DataKd:  3.20E+4nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT3 (114 to 380 residues) expressed in Escherichia coli assessed as dissociation constant by micros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50591386(CHEMBL5171187)
Affinity DataKd:  1.38E+5nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT3 (114 to 380 residues) expressed in Escherichia coli assessed as dissociation constant by micros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50607105(CHEMBL5218728)
Affinity DataEC50: <5.00E+3nMAssay Description:Modulation of human Sirt3 (118 to 399 residues) deacetylation activity under non-steady state assessed as substrate deacetylation at low enzyme conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-diallylbiphenyl-2,4'-diol | CHEMBL16901 | cid...)
Affinity DataKd:  1.01E+3nMAssay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-diallylbiphenyl-2,4'-diol | CHEMBL16901 | cid...)
Affinity DataKd:  970nMAssay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant using acetylated MnSOD peptide as substrate by microscale the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50607106(CHEMBL5220997)
Affinity DataKd:  7.30E+3nMAssay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant using acetylated MnSOD peptide as substrate by microscale the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50607106(CHEMBL5220997)
Affinity DataKd:  6.60E+3nMAssay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant using acetylated MnSOD peptide as substrate in presence of ho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-diallylbiphenyl-2,4'-diol | CHEMBL16901 | cid...)
Affinity DataKd:  290nMAssay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant of ternary complex using acetylated MnSOD peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50607105(CHEMBL5218728)
Affinity DataKoff:  20.1s-1Assay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant (Kon) by short DNA nano levers based switchSENSE microfluid b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50607105(CHEMBL5218728)
Affinity DataKon:  0.220M-1s-1Assay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant (Koff) by short DNA nano levers based switchSENSE microfluid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50607105(CHEMBL5218728)
Affinity DataKd:  4.60E+3nMAssay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant by short DNA nano levers based switchSENSE microfluid bio-chi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
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