14 articles for thisTarget
              
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Quantitative structure-activity relationship of human neutrophil collagenase (MMP-8) inhibitors using comparative molecular field analysis and X-ray structure analysis.

Hoechst Marion Roussel
 
Synthesis, structure-activity relationships, and pharmacokinetic properties of dihydroorotate dehydrogenase inhibitors: 2-cyano-3-cyclopropyl-3-hydroxy-N-[3'-methyl-4'-(trifluoromethyl)phenyl ] propenamide and related compounds.

Hoechst Marion Roussel
 
Structure-activity relationships of a series of novel (piperazinylbutyl)thiazolidinone antipsychotic agents related to 3-[4-[4-(6-fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]-2,5,5- trimethyl-4-thiazolidinone maleate.

Hoechst Marion Roussel
 
RGD mimetics containing a central hydantoin scaffold: alpkha(v)beta3 vs alpha(IIb)beta3 selectivity requirements.

Hoechst Marion Roussel
 
Hydroxyoxazolidines as alpha-aminoacetaldehye equivalents: novel inhibitors of calpain.

Hoechst Marion Roussel
 
Potent nonpeptide endothelin antagonists: synthesis and structure-activity relationships of pyrazole-5-carboxylic acids.

Hoechst Marion Roussel
 
Nonpeptide endothelin antagonists: from lower affinity pyrazol-5-ols to higher affinity pyrazole-5-carboxylic acids.

Hoechst Marion Roussel
 
Affinity and selectivity of matrix metalloproteinase inhibitors: a chemometrical study from the perspective of ligands and proteins.

Hoechst Marion Roussel
 
Novel series of O-substituted 8-quinolines and 4-benzothiazoles as potent antagonists of the bradykinin B2 receptors.

Hoechst Marion Roussel
 
The synthesis of ketomethylene pseudopeptide analogues of dipeptide aldehyde inhibitors of calpain.

Hoechst Marion Roussel
 
Inhibition of human neutrophil elastase. 4. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of P2-modified, orally active peptidyl pentafluoroethyl ketones.

Hoechst Marion Roussel
 
Compounds for the inhibition of cyclophilins and uses thereof

Merck Patent
 
Carbamate-appended N-alkylsulfonamides as inhibitors of gamma-secretase.

Bristol-Myers Squibb
 
4-substituted cyclohexyl sulfones as potent, orally active gamma-secretase inhibitors.

Merck Research Laboratories