BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 728K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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18 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.EBI
Karolinska Institutet
Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1.EBI
Karolinska Institutet
Towards small molecule inhibitors of mono-ADP-ribosyltransferases.EBI
Karolinska Institutet
Structure-guided design of novel thiazolidine inhibitors of O-acetyl serine sulfhydrylase from Mycobacterium tuberculosis.EBI
Karolinska Institutet
Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity.EBI
Karolinska Institutet
Synthesis and evaluation of [¹8F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B).EBI
Karolinska Institutet
Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor.EBI
Karolinska Institutet
Synthesis of three novel fluorine-18 labeled analogues of L-deprenyl for positron emission tomography (PET) studies of monoamine oxidase B (MAO-B).EBI
Karolinska Institutet
Structure-based discovery of small molecule inhibitors of FKBP51-Hsp90 protein-protein interaction.EBI
Karolinska Institutet
Profiling of in vitro activities of urea-based inhibitors against cysteine synthases from Mycobacterium tuberculosis.EBI
Karolinska Institutet
Small molecule therapeutics for tauopathy in Alzheimer's disease: Walking on the path of most resistance.EBI
Karolinska Institutet
Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability.EBI
Karolinska Institutet
Development of a novel fluorine-18 labeled deuterated fluororasagiline ([(18)F]fluororasagiline-D2) radioligand for PET studies of monoamino oxidase B (MAO-B).EBI
Karolinska Institutet
Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 1: Triazoles, triazolopyrimidines, triazinoindoles, quinoline hydrazones and arylpiperazines.EBI
Karolinska Institutet
Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 2: Pyridone- and pyrimidinone-derived systems.EBI
Karolinska Institutet
Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors.EBI
Karolinska Institutet
Discovery and structure-activity relationship of P1-P3 ketoamide derived macrocyclic inhibitors of hepatitis C virus NS3 protease.BDB
Schering-Plough Research Institute