27 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Azaphilones from an Acid Mine Extremophile Strain of a Pleurostomophora sp.
Memorial Sloan-Kettering Cancer Center
Experimental and structural testing module to analyze paralogue-specificity and affinity in the Hsp90 inhibitors series.
Memorial Sloan-Kettering Cancer Center
Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associatedµ opioid receptor (MOR-1) splice variants.
Memorial Sloan-Kettering Cancer Center
Generation of novel radiolabeled opiates through site-selective iodination.
Memorial Sloan-Kettering Cancer Center
Diversity-oriented synthesis: exploring the intersections between chemistry and biology.
Memorial Sloan-Kettering Cancer Center
Discovery and development of heat shock protein 90 inhibitors.
Memorial Sloan-Kettering Cancer Center
Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase.
Memorial Sloan-Kettering Cancer Center
Role of metalation in the topoisomerase IIa inhibition and antiproliferation activity of a series ofa-heterocyclic-N4-substituted thiosemicarbazones and their Cu(II) complexes.
Memorial Sloan-Kettering Cancer Center
Structure-activity relationships of 6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)pyrido[2,3-d]pyrimidin-7-ones: toward selective Abl inhibitors.
Memorial Sloan-Kettering Cancer Center
Synthesis and biological evaluation of a fluorine-18 derivative of dasatinib.
Memorial Sloan-Kettering Cancer Center
Synthesis of a red-shifted fluorescence polarization probe for Hsp90.
Memorial Sloan-Kettering Cancer Center
Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90.
Memorial Sloan-Kettering Cancer Center
Evaluation of 8-arylsulfanyl, 8-arylsulfoxyl, and 8-arylsulfonyl adenine derivatives as inhibitors of the heat shock protein 90.
Memorial Sloan-Kettering Cancer Center
Synthesis of novel fluorescent probes for the molecular chaperone Hsp90.
Memorial Sloan-Kettering Cancer Center
Recent developments of small molecule γ-secretase modulators for Alzheimer's disease.
Memorial Sloan-Kettering Cancer Center
Development of CBAP-BPyne, a probe for γ-secretase and presenilinase.
Memorial Sloan-Kettering Cancer Center
Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70.
Memorial Sloan-Kettering Cancer Center
Sandmeyer reaction repurposed for the site-selective, non-oxidizing radioiodination of fully-deprotected peptides: studies on the endogenous opioid peptide α-neoendorphin.
Memorial Sloan-Kettering Cancer Center
Development of clickable active site-directed photoaffinity probes for γ-secretase.
Memorial Sloan-Kettering Cancer Center
Stereo-controlled synthesis of novel photoreactive gamma-secretase inhibitors.
Memorial Sloan-Kettering Cancer Center
Similarity between rat brain nicotinic alpha-bungarotoxin receptors and stably expressed alpha-bungarotoxin binding sites.
Mcgill University