12 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Further investigation of inhibitors of MRSA pyruvate kinase: Towards the conception of novel antimicrobial agents.
Simon Fraser University
Optimization and structure-activity relationships of a series of potent inhibitors of methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as novel antimicrobial agents.
Simon Fraser University
Probing the active-site requirements of human intestinal N-terminal maltase-glucoamylase: Synthesis and enzyme inhibitory activities of a six-membered ring nitrogen analogue of kotalanol and its de-O-sulfonated derivative.
Simon Fraser University
Selectivity of 3'-O-methylponkoranol for inhibition of N- and C-terminal maltase glucoamylase and sucrase isomaltase, potential therapeutics for digestive disorders or their sequelae.
Simon Fraser University
Probing the active-site requirements of human intestinal N-terminal maltase glucoamylase: the effect of replacing the sulfate moiety by a methyl ether in ponkoranol, a naturally occurringa-glucosidase inhibitor.
Simon Fraser University
A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo.
Simon Fraser University
Synthesis of a biologically active isomer of kotalanol, a naturally occurring glucosidase inhibitor.
Simon Fraser University
Synthesis and inhibition studies of sulfur-substituted squalene oxide analogues as mechanism-based inhibitors of 2,3-oxidosqualene-lanosterol cyclase.
Simon Fraser University
Carbocycles related to oseltamivir as influenza virus group-1-specific neuraminidase inhibitors. Binding to N1 enzymes in the context of virus-like particles.
Simon Fraser University
Characterization of the binding site for a novel class of noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists.
Pfizer
Muscarinic receptor binding sites of the M4 subtype in porcine lung parenchyma.
Case Western Reserve University