35 articles for thisTarget
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Strategy for designing selectivea-l-rhamnosidase inhibitors: Synthesis and biological evaluation of l-DMDP cyclic isothioureas.

University of Toyama
Structural Insight into the Interactions between Death-Associated Protein Kinase 1 and Natural Flavonoids.

University of Toyama
In silico and pharmacological screenings identify novel serine racemase inhibitors.

University of Toyama
Inhibitory activities of propolis and its promising component, caffeic acid phenethyl ester, against amyloidogenesis of human transthyretin.

University of Toyama
Docking and SAR studies of calystegines: binding orientation and influence on pharmacological chaperone effects for Gaucher's disease.

University of Toyama
Synthesis and biological evaluation of N-(2-fluorophenyl)-2ß-deoxyfuconojirimycin acetamide as a potent inhibitor fora-l-fucosidases.

University of Toyama
Rational design and synthesis of 4-substituted 2-pyridin-2-ylamides with inhibitory effects on SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2).

University of Toyama
Sesquiterpenes from the rhizomes of Curcuma heyneana.

University of Toyama
Synthesis and evaluation of novel photoreactive alpha-amino acid analog carrying acidic and cleavable functions.

University of Toyama
a-1-C-butyl-1,4-dideoxy-1,4-imino-l-arabinitol as a second-generation iminosugar-based orala-glucosidase inhibitor for improving postprandial hyperglycemia.

University of Toyama
Cytochrome P450 3A4 inhibitory constituents of the wood of Taxus yunnanensis.

University of Toyama
Isolation of glycosidase-inhibiting hyacinthacines and related alkaloids from Scilla socialis.

University of Toyama
Design, synthesis, and biological evaluation of novel (1-thioxo-1,2,3,4-tetrahydro-ß-carbolin-9-yl)acetic acids as selective inhibitors for AKR1B1.

University of Toyama
Docking and SAR studies of D- and L-isofagomine isomers as humanß-glucocerebrosidase inhibitors.

University of Toyama
6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2.

University of Toyama
2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease.

University of Toyama
Synthesis and evaluation of A-seco type triterpenoids for anti-HIV-1protease activity.

University of Toyama
Possible involvement of radical intermediates in the inhibition of cysteine proteases by allenyl esters and amides.

University of Toyama
Synthesis of poison-frog alkaloids 233A, 235U, and 251AA and their inhibitory effects on neuronal nicotinic acetylcholine receptors.

University of Toyama
Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.

University of Toyama
Design and Pharmacological Chaperone Effects of

University of Toyama
Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis.

University of Toyama
Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis.

University of Toyama
Design and synthesis of pyrido[2,3-d]pyrimidine derivatives for a novel PAC1 receptor antagonist.

University of Toyama
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University of Toyama
Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors.

University of Toyama
Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis.

University of Toyama
Transthyretin Amyloidogenesis Inhibitors: From Discovery to Current Developments.

University of Toyama
Synthesis of a novel and potent small-molecule antagonist of PAC1 receptor for the treatment of neuropathic pain.

University of Toyama
Crown Ethers as Transthyretin Amyloidogenesis Inhibitors.

University of Toyama
Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening.

University of Toyama
Inhibition of the dimerization and active site of HIV-1 protease by secondary metabolites from the Vietnamese mushroom Ganoderma colossum.

University of Toyama
Synthesis of dammarane-type triterpene derivatives and their ability to inhibit HIV and HCV proteases.

University of Toyama
Anti-HIV-1 protease activity of lanostane triterpenes from the vietnamese mushroom Ganoderma colossum.

University of Toyama
Design and synthesis of novel anti-hyperalgesic agents based on 6-prenylnaringenin as the T-type calcium channel blockers.

University of Toyama